Diagnostic value of SFRP1 as a favorable predictive and prognostic biomarker in patients with prostate cancer. by Lei Zheng, Dongchen Sun, Wentao Fan, Zhiwei Zhang, Quanlin Li, Tao Jiang

“…The aim of this study was to examine whether the expression of SFRP1 and β-catenin is associated with the clinical-pathologic features of patients with prostate cancer (PCa), and to evaluate their potential roles as predictive and prognostic biomarkers. …”
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Pathological Insights into Liquid Biopsy: Role of Circulating Tumor DNA in Oral Cancer Prognosis and Therapy by Raima Kalhoro, Fatima Sarfraz, Shahzaman Memon, Ayesha Atique, Sajid Ali Majeedano, Muqaddas Fatima, Kanwal Ehsan Khan

“…This study aimed at Pathological Insights into Liquid Biopsy by evaluating the role of circulating tumor DNA in oral cancer Prognosis and Therapy. …”
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RelVid: Relational Learning with Vision-Language Models for Weakly Video Anomaly Detection by Jingxin Wang, Guohan Li, Jiaqi Liu, Zhengyi Xu, Xinrong Chen, Jianming Wei

“…Weakly supervised video anomaly detection aims to identify abnormal events in video sequences without requiring frame-level supervision, which is a challenging task in computer vision. …”
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The prevalence of Listeria monocytogenes and Staphylococcus aureus and their virulence genes in bulk tank milk in Kosovo by Ibrahim Mehmeti, Hysen Bytyqi, Skender Muji, Ingolf F Nes, Dzung B Diep

“…Microbiological quality is an important aspect in evaluating the quality of milk. Methodology: A total of 603 bulk tank milk samples from 221 farms distributed across ten different regions were collected for milk quality assessment. …”
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Morphology and Phylogeny of Cytospora erumpens, Unreported Species Isolated from Apple Trunk in Korea by Jun-Woo Choi, Gwang-Jae Lim, Chang-Gi Back, In-Kyu Kang, Seung-Yeol Lee, Hee-Young Jung

“…The cultural and morphological characteristics of the isolated strain were evaluated using potato dextrose and malt extract agar (MEA). …”
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Immuno-informatics analyses of important esophageal cancer associated viruses for multi-epitope vaccine design by Zafer Saad Al Shehri

“…Notably, several oncogenic viruses have been implicated in EC pathogenesis, prompting the exploration of epitope-based vaccines through immunoinformatics.MethodsUsing immunoinformatics and bioinformatics approaches, we designed a novel multi-epitope vaccine targeting viral agents associated with EC. Protein sequences of ten viral candidates were retrieved from the UniProt database and evaluated for antigenicity using the VaxiJen server. …”
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Optimization of TaqMan-based quantitative PCR diagnosis for Entamoeba histolytica using droplet digital PCR. by Akira Kawashima, Yasuaki Yanagawa, Takayuki Chikata, Rieko Shimogawara, Daisuke Mizushima, Kiyoto Tsuchiya, Kenji Yagita, Hiroyuki Gatanaga, Koji Watanabe

“…Shotgun metagenomic sequencing suggested microbial-independent false positive reactions contributed to these discrepancies, although specific reactants were unidentified.…”
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Clinical manifestations in Egyptian Pompe disease patients: Molecular variability and enzyme replacement therapy (ERT) outcomes by Mohamed Abdelghafar Hussein, Heba ElTaher, Ranim Mahmoud, Donia Sobh, Mohammad Al-Haggar

“…The diagnosis was confirmed by molecular genetic testing using PCR amplification and sequencing of the acid alpha-glucosidase (GAA) gene. …”
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Recognition of field-grown tobacco plant type characteristics based on three-dimensional point cloud and ensemble learning by JIA Aobo, DONG Tianhao, ZHANG Yan, ZHU Binglin, SUN Yanguo, WU Yuanhua, SHI Yi, MA Yuntao, GUO Yan

“…To develop an efficient method for quantifying tobacco plant types in the field, the three-dimensional (3D) point clouds of individual plant of five tobacco cultivars were reconstructed based on multi-view image sequences using the structure from motion method. According to the plant type characteristic indexes commonly used, ten phenotypic parameters such as plant height, top width, bottom width, and maximum width of leaf layer were automatically extracted based on the 3D point cloud of tobacco plant, and the calculation accuracy was evaluated based on the plant height and maximum width of leaf layer measured manually in situ in the field. …”
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The frequencies of CYP2C19*2, *3, and *17 alleles and their impact on the clinical efficacy of doubled maintenance dose of clopidogrel in Syrian patients with coronary artery disea... by Nour Haj Saleh, Lama A. Youssef

“…CYP2C19 genotypes were determined by PCR, followed by Sanger sequencing. Clinical outcomes, including major acute cardiovascular events (MACE) and bleeding events, were monitored over 18–24 months. …”
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Study on heterogeneity of vascularity and cellularity via multiparametric MRI habitat imaging in breast cancer by Xiaolei Zhang, Xiaoyan Chen, Yao Fu, Han Zhou, Yan Lin

“…Abstract Background This study aimed to visually analyze the heterogeneity of vascularity and cellularity across different sub-regions of breast cancer using habitat imaging (HI) to predict human epidermal growth factor receptor 2 (HER2) expression and evaluate the effectiveness of neoadjuvant therapy (NAT) in breast cancer patients. …”
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Survival benefits of Cytoreductive Nephrectomy in patients with metastatic renal cell carcinoma: evidence from a SEER-based retrospective cohort study. by Xiongwu Peng, Lingxing Duan, Qi Wu, Shiping Wu, Wenfeng Wang, Runlin Shi

“…Further prospective studies are warranted to optimize patient selection and treatment sequencing.…”
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A multi-objective evolutionary algorithm for detecting protein complexes in PPI networks using gene ontology by Mustafa N. Abbas, David Broneske, Gunter Saake

“…This allows us to evaluate how perturbations in protein interactions affect the algorithm’s performance compared to other approaches. …”
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Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure by Zhenyu Zhao, Zhixi Hu, Lin Li

“…The changes in gut microbiota structure were analyzed by 16S rRNA high-throughput sequencing, the content of short-chain fatty acids (SCFAs) was detected by targeted metabolomics technology, and cardiac function and energy metabolism-related indicators were evaluated.ResultsMyocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.ConclusionShenfu Injection in treating HF may improve myocardial energy metabolism and intestinal health by regulating gut microbiota, especially the abundance of SCFAs-producing bacteria Akkermansia and Blautia, thereby exerting therapeutic effects. …”
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The chemosynthetic biofilm microbiome of deep-sea hydrothermal vents across space and time by Ashley Grosche, Matteo Selci, Francesco Smedile, Donato Giovannelli, Sara Borin, Nadine Le Bris, Costantino Vetriani

“…Transcripts from 16S rRNA-based amplicon sequencing revealed that Campylobacterota of the Sulfurimonas and Sulfurovum genera dominated newly-formed biofilms across all biological regimes. …”
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Alterations in Gut Microbiome Composition and Barrier Function Are Associated with Reproductive and Metabolic Defects in Women with Polycystic Ovary Syndrome (PCOS): A Pilot Study. by Lisa Lindheim, Mina Bashir, Julia Münzker, Christian Trummer, Verena Zachhuber, Bettina Leber, Angela Horvath, Thomas R Pieber, Gregor Gorkiewicz, Vanessa Stadlbauer, Barbara Obermayer-Pietsch

“…<h4>Methods</h4>16S rRNA gene amplicon sequencing was performed on stool samples from 24 PCOS patients and 19 healthy controls. …”
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Predictions of Multilevel Linguistic Features to Readability of Hong Kong Primary School Textbooks: A Machine Learning Based Exploration by Zhengye Xu, Yixun Li, Duo Liu

“…Model performance was evaluated by prediction accuracy and the mean absolute error between predicted and actual readability. …”
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Quantifying Systematic Uncertainties in White Dwarf Cooling Age Determinations by Praneet Pathak, Simon Blouin, Falk Herwig

“…We provide a table of our simulation results that can be used to evaluate the systematic model uncertainty based on a white dwarf’s T _eff and mass. …”
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Statistical Optimization of Solid-State Fermentation by Aspergillus oryzae for Valorization of Olive Cake and Its Application as a Poultry Feed by Abdalla Sayed Mohamed Korayem, Fafy A. Mohammed, Samah H. Abu-Hussien, Fatma M. Abosamra, Salma Nour El-Dein, Hassan. A.F. Rahmy

“…These isolates were evaluated for their ability to valorize OC as poultry feed by reducing fiber content and increasing protein content under solid-state fermentation. …”
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Interleukin-6 gene polymorphism in Saudi population with recurrent aphthous stomatitis by Samah Jameel Saeed Shabana, Muhammad Hamid Zaini Mutawakkil, Hassan Mamdouh Aly El–Ashmaoui, Fathya Mohammed Abdel-Qawi Zahran

“…The genotypes of IL-6 gene −174G/C polymorphisms were determined using polymerase chain reaction and sequencing. Results: Four SNPs were analyzed, one known mutation which been evaluated as a risk factor for RAS, and three new mutations were investigated. …”
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