Predictive and Prognostic Implications of Mutation Profiling and Microsatellite Instability Status in Patients with Metastatic Colorectal Carcinoma by Jianhua Liu, Weiqiang Zeng, Chengzhi Huang, Junjiang Wang, Dongyang Yang, Dong Ma

“…The clinical value of these abnormalities was statistically analyzed, and prognostic value of different treatment regimens was also evaluated. Among 461 mCRC patients, mutations in RAS, BRAF, and MSI-high (MSI-H) status were observed in 45.3% (209/461), 5.6% (26/461), and 6.5% (30/461) of cases, respectively. …”
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Reduction in mitochondrial DNA methylation leads to compensatory increase in mitochondrial DNA content: novel blood-borne biomarkers for monitoring occupational noise by Jia-Hao Yang, Zhuo-Ran Li, Zhuo-Zhang Tan, Wu-Zhong Liu, Qiang Hou, Pin Sun, Xue-Tao Zhang

“…Method: We recruited 306 factory workers, using average binaural high-frequency hearing thresholds from pure-tone audiometry to assess noise exposure. MtDNA damage was evaluated through mitochondrial DNA copy number (mtDNAcn) and lesion rate, and mtDNA methylation changes were identified via pyrophosphate sequencing. …”
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Prognostic significance of clonal hematopoiesis in STEMI: a 10-year follow-up reveals high-risk gene mutations by Wen-Lang Fan, Jih-Kai Yeh, Li-Ching Hsieh, Ming-Lung Tsai, Ming-Yun Ho, Yi-Chun Huang, I-Chang Hsieh, Ming-Shien Wen, Chao-Yung Wang

“…Methods Whole-exome sequencing was performed in a cohort of 101 patients presenting with STEMI who underwent emergency percutaneous coronary intervention. …”
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Oral Administration of Propolis and Lysozyme Combination Improves Feline Oral Health and Modulates Systemic Inflammatory and Oxidative Responses by Longjiao Wang, Qianqian Chen, Weiwei Wang, Hao Dong, Xiaohan Chang, Lishui Chen, Ran Wang, Yaoxing Chen, Pengjie Wang, Shuxing Chen, Wei Xiong, Yixuan Li

“…Supragingival microbiota were analyzed via 16S rRNA gene sequencing, alongside assessments of volatile sulfur compounds (VSCs), oral health indices, and systemic inflammatory, oxidative, and immune markers. …”
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Effect of mobile app-based oral hygiene instructions on clinical parameters, oral bacterial diversity, and composition of subgingival microbiota in periodontitis patients by Melinda Rabekka Purba, Mardikacandra Manggala Putra, Benso Sulijaya, Adityo Widaryono, Valdy Hartono, Yoga Setiadharma, Aurelle Khadeeja Rizany, Fatimah Maria Tadjoedin, Marie Rossini Carmela T. Lachica

“…Various OHI approaches have been explored, including mobile apps.Objective To evaluate the mobile app-based OHI’s effect on periodontitis management by analyzing clinical parameters and subgingival microbiota.Methods Forty-four periodontitis patients were randomly assigned into two groups. …”
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First isolation and full-length genome analysis of a new RNA virus, Wenzhou sobemo-like virus 4 from Culex tritaeniorhynchus by Yuli Zhang, Yu Bi, Xiaohui Zou, Zhen Wu, Hengyi Sun, Jian Song, Guoyu Niu

“…Pairwise distance analysis indicated that 11 partially amplified sequences shared a high nucleotide identity. The objective of this study was to isolate and characterize WZSLV4 from mosquito populations in Shandong Province, China, and to evaluate its growth characteristics in different cell lines to better understand its biological properties and potential pathogenicity. …”
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Intestinal bacteria translocation promotes β-cell dysfunction in DIO mice by Xiang-Fang Yu, Chetali Gurung, Zhongjia Yu, Wei Xiao, Goher Kerem, Bin Teng, Jian V. Zhang, Zhe Su, Yongjin Zhou, Pei-Gen Ren

“…In this study, we aimed to precisely assess the changes in intestinal bacteria translocation (IBT) from gut to the pancreas using combinations of FISH, 16S rRNA amplicon sequencing, and deep learning-assisted methods to track IBT in diet-induced obese (DIO) and antibiotic-induced microbiota disruption (AIMD)-DIO mouse models. …”
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Transcriptome-wide RNA 5-methylcytosine profiles of human iPSCs and iPSC-derived cardiomyocytes by Szu-Ying Chen, Yi-Hsien Fang, Chen-Yu Huang, Jou-Hsien Wu, Yan-Shen Shan, Yen-Wen Liu, Po-Hsien Huang

“…The RNA m5C profiles in this dataset allow the evaluations of the m5C level and distribution of specific m5C loci and facilitate understanding of the m5C epitranscriptomic landscape in biological functions of hPSC-CM beyond in vivo transplantation barriers.…”
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Human-machine interaction in mechanical systems through sensor enabled wearable augmented reality interfaces by K. Balamurugan, G. Sudhakar, Kavin Francis Xavier, N. Bharathiraja, Gaganpreet Kaur

“…The dynamic gesture recognition system uses Random Forest as its lightweight machine learning model to achieve 93.4 % accuracy in mapping gestures to command sequences which represents a 14.6 % enhancement above conventional static models. …”
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Correlation between dominant bacterial community and non-volatile organic compounds during the fermentation of shrimp sauces by Ruichang Gao, Huijie Liu, Ying Li, Hongying Liu, Yue Zhou, Li Yuan

“…The quality of salt-fermented shrimp sauce was evaluated in this work by determining the total volatile basic nitrogen (TVB-N), the amino acid nitrogen (AAN), organic acid, 5'-nucleotide and free amino acids (FAA). …”
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Regulatory Effects of SLC7A2‐CPB2 on Lymphangiogenesis: A New Approach to Suppress Lymphatic Metastasis in HNSCC by Kai Song, Yanshi Li, Kai Yang, Tao Lu, Min Wang, Zhihai Wang, Chuan Liu, Ming Yu, Mengna Wang, Zhaobo Cheng, Min Pan, Guohua Hu

“…Methods Tissue samples (HNSCC) were examined by transcriptome sequencing, and the core genes associated with LNM were detected via bioinformatics analysis. …”
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Modified Huangqi Shengmai Yin enhances ruminal microbiome and metabolites activity in dairy cows with subclinical mastitis by Chenyibo Zhang, Baoling Zhang, Yuqiong Li, John P. Kastelic, Xiaoping Li, Xiaofang Tong, A. Yao, Chuang Xu, Bo Han, Jian Gao

“…After a 3-day treatment regimen, the therapeutic effects were evaluated. 16S diversity sequencing and metabolomics were used to elucidate the therapeutic mechanism of HSY.ResultsThe SCM was significantly alleviated after the 3-day treatment with HSY. …”
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Soil Fungal Diversity, Community Structure, and Network Stability in the Southwestern Tibetan Plateau by Shiqi Zhang, Zhenjiao Cao, Siyi Liu, Zhipeng Hao, Xin Zhang, Guoxin Sun, Yuan Ge, Limei Zhang, Baodong Chen

“…This study employed ITS high-throughput sequencing to evaluate soil fungal diversity, community composition, and co-occurrence networks across alpine meadows, desert steppes, and alpine shrublands in the southwestern Tibetan Plateau. …”
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A dataset of chronic nicotine-induced genes in breast cancer cellsUniversity of California San Diego Library Digital Collections by Samson Mugisha, Shreyas Labhsetwar, Devam Dave, Richard Klemke, Jay S. Desgrosellier

“…We then evaluated differential gene expression between chronic nicotine and control cells for each individual cluster or in the whole sample using PyDESeq2. …”
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Bifidobacterium animalis subsp. Lactis BX-BC08 modulates gut microbiota and secretes alpha-Ketoglutaric acid to alleviate MC903-induced atopic dermatitis by Jiamin Zhao, Ling Kui, Jinqun Huang, Jie Deng, Lingjun Liu, Chenwei Zhu, Yanqiang Shi, Chengyi Li, Yue Xiao, Jinshi Yu, Qing Li, Bin Yang, Bingfeng Leng, Hung Chan

“…Design The immunosuppressive and anti-inflammatory effects of BX-BC08 were evaluated in a MC903-induced AD mouse model. Gut microbiota composition was analyzed by metagenomic sequencing, while high-performance liquid chromatography-mass spectrometry (HPLC-MS) was employed to identify anti-inflammatory molecules produced by B. lactis BX-BC08. …”
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Neoadjuvant or concurrent atezolizumab with chemoradiation for locally advanced cervical cancer: a randomized phase I trial by Jyoti Mayadev, Dmitriy Zamarin, Wei Deng, Heather A. Lankes, Giulio Pesci, Hayeon Kim, Junzo P. Chino, Barbara Banbury, Ned Sherry, Elad Sharon, Sharad A. Ghamande, Catherine Ferguson, Loren Mell, Laura Holman, Cara Mathews, David O’Malley, Alexander Olawaiye, Elizabeth Hopp, Charles Leath, Larry Copeland, Robert Mannel, Roisin O’Cearbhaill, Carol Aghajanian, Russell J. Schilder

“…Abstract Combined immune checkpoint blockade (ICB) and chemoradiation (CRT) is approved in patients with locally advanced cervical cancer (LACC) but optimal sequencing of CRT and ICB is unknown. NRG-GY017 (NCT03738228) was a randomized phase I trial of atezolizumab (anti-PD-L1) neoadjuvant and concurrent with CRT (Arm A) vs. concurrent with CRT (Arm B) in patients with high-risk node-positive LACC. …”
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The effects of repeated fecal transplantation and activated charcoal treatment on gut dysbiosis induced by concurrent ceftriaxone administration in mice by Sarinya Kumpunya, Kornthara Kawang, Kraiwit Pollapong, Voraphoj Nilaratanakul

“…Gut microbiomes were analyzed using 16 S rRNA gene sequencing, and intestinal mucosal pathology was evaluated through H&E staining. …”
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Assessing the Impact of Force Feedback in Musical Knobs on Performance and User Experience by Ziyue Piao, Christian Frisson, Bavo Van Kerrebroeck, Marcelo M. Wanderley

“…To support our study, we developed the Bend-aid system, a web-based sequencer with pre-designed haptic modes for pitch modulation, integrated with TorqueTuner, a rotary haptic device that controls pitch through programmable haptic effects. …”
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Preparation of pH-Responsive Tanshinone IIA-Loaded Calcium Alginate Nanoparticles and Their Anticancer Mechanisms by Tianying Ren, Jing Wang, Yingxin Ma, Yichen Huang, Somy Yoon, Lijun Mu, Ru Li, Xuekun Wang, Lina Zhang, Pan Li, Lusha Ji

“…We also utilized RNA sequencing to further investigate the underlying anticancer mechanisms of Tan IIA/CA nanoparticles. …”
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Metagenomic and metabolomic analysis of gut microbiome's role in spinal cord injury recovery in rats by Jieqi Zhang, Xihan Ying, Rong Hu, Yi Huang, Ruoqi Wang, Lei Wu, Dexiong Han, Ruijie Ma, Kelin He

“…Fecal samples were collected for whole-genome metagenomic sequencing, and serum samples were analyzed using untargeted metabolomics. …”
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