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6841
Mung Bean Peptides Alleviate Dextran-Sulfate-Sodium-Induced Colitis Symptoms in Mice by Protecting the Intestinal Mechanical Barrier and Regulating Gut Microbiota
Published 2025-04-01“…In this study, the structural characteristics of MBPs were examined by determining various parameters, such as amino acid composition, molecular weight distribution, and peptide sequences, thereby structurally demonstrating their anti-inflammatory potential. …”
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6842
Co-administration of isoprenaline and phenylephrine induced a new HFrEF mouse model through activation of both SNS and RAAS
Published 2025-03-01“…The use of drug induced heart failure models has greatly facilitated basic research and reduced the disadvantages of time-consuming and labor-intensive surgical modeling.MethodsIn our experiments, we used a combination of isoprenaline (ISO) and phenylephrine (PE) for modeling; we aimed to evaluate whether it is superior to conventional drug-induced models, especially those induced by isoprenaline alone. …”
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6843
Assessing the Biodegradation of Low-Density Polyethylene Films by <i>Candida tropicalis</i> SLNEA04 and <i>Rhodotorula mucilaginosa</i> SLNEA05
Published 2024-12-01“…Biodegradation of these polymers relies on microorganisms capable of decomposing them, generally through the biodeterioration, biofragmentation, assimilation, and mineralization stages. This study evaluates the contribution and efficacy of indigenous soil yeasts isolated from a northeastern Algerian landfill in degrading low-density polyethylene (LDPE) plastic bag films. …”
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6844
Bacillus cereus is a key microbial determinant of intractable otitis media with effusion
Published 2025-05-01“…This study aimed to evaluate the microbial profile of MEE samples and to determine whether there were microbial differences between the MEE microbiota of patients with intractable OME and those with rapidly cured OME. …”
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6845
Laxative effect of Zengye granule by modulating the SCF/c-Kit pathway and gut microbiota in constipated mice
Published 2025-06-01“…The laxative effect was evaluated based on the discharge time of the first black stool, fecal number, fecal weight, intestinal propulsion rate, and intestinal moisture content. …”
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6846
Deglycosylated azithromycin alleviates cisplatin-evoked constipation in mice by altering host metabolome and gut microbiota composition
Published 2025-05-01“…The gut microbiota composition was analyzed using 16S rRNA sequencing, and metabolic changes were evaluated through untargeted metabolomics of fecal samples.ResultsDeg-AZM significantly enhanced intestinal motility in the mice with cisplatin-evoked constipation. …”
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6847
LncRNA APTR amplification serves as a potential glioma biomarker and promotes glioma progression via miR-6734-5p/ TCF7/LEF1 axis
Published 2025-06-01“…Correlations between APTR and patient prognosis were evaluated using Kaplan-Meier survival and COX regression analyses. …”
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6848
Snapshot Japan 2023: the first camera trap dataset under a globally standardised protocol in Japan
Published 2025-03-01“…There is an urgent need to develop global observation networks to quantify biodiversity trends for evaluating achievements of targets of Kunming-Montreal Global Biodiversity Framework. …”
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6849
Three-dimensional printing template for intraoperative localization of pulmonary nodules in the pleural cavityCentral MessagePerspective
Published 2022-12-01“…The precision of the nodule localization and associated complications were evaluated. Results: Twelve patients were finally included in this study. …”
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6850
Impact of Ozonated Water on the Fungal Colonies, Diversity and Fruit Quality of Grapevine in Northern Europe
Published 2025-05-01“…The fungal population on the phyllosphere of grapevine leaves and berries was evaluated using the serial dilution plating method. …”
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6851
An Integrative Genomics Approach for the Discovery of Potential Clinically Actionable Diagnostic and Prognostic Biomarkers in Colorectal Cancer
Published 2025-07-01“…The recent surge of next generation sequencing has enabled genomic analysis of colorectal cancer genomes. …”
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6852
Investigating the In Vivo Effects of Anti-Prion Protein Nanobodies on Prion Disease with AAV Vector
Published 2025-02-01“…In this study, we investigated the potential for in vivo expression of anti-PrP<sup>C</sup> nanobodies and evaluated their impact on prion disease. The coding sequences of three nanobodies were packaged into recombinant adeno-associated virus (rAAV) and were administered via intracerebroventricular (ICV) injection in newborn mice. …”
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6853
Genomic Selection in Alfalfa Across Multiple Ploidy Levels: A Comparative Study Using Machine Learning and Bayesian Methods
Published 2024-11-01“…Genomic selection (GS) based on genotyping-by-sequencing (GBS) data, if it achieves moderate to high accuracy, has the potential to significantly shorten breeding cycles for complex traits and accelerate genetic progress. …”
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6854
Chitosan oligosaccharide and Enteromorpha prolifera polysaccharides as additives affect the bacterial community and optimize the compost performance
Published 2025-07-01“…Here, we conducted composting experiments using agricultural wastes (cow manure, rice husks, and tomato residues) as substrates, and systematically evaluated the effects of chitosan oligosaccharide (COS) and Enteromorpha prolifera polysaccharides (EPP) supplementation through physicochemical analysis and high-throughput sequencing. …”
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6855
Neutrophil-to-Lymphocyte Ratio as a Microbiota-Dependent Indicator of Immune Dysfunction and a Long-Term Prognostic Factor in Patients with Cirrhosis
Published 2025-08-01“…Aim: to evaluate the neutrophil-to-lymphocyte ratio (NLR) as a microbiota-dependent indicator of immune dysfunction and a long-term prognostic factor in patients with cirrhosis.Materials and methods. …”
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6856
EnsembleNPPred: A Robust Approach to Neuropeptide Prediction and Recognition Using Ensemble Machine Learning and Deep Learning Methods
Published 2025-06-01“…To support this effort, computational prediction tools have emerged as a cost-effective approach for prioritizing candidate sequences for experimental validation. In this study, we propose EnsembleNPPred, an ensemble learning framework that integrates traditional machine learning (ML) models with a deep learning (DL) component. …”
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6857
Variant filters using segregation information improve mapping of nectar‐production genes in sunflower (Helianthus annuus L.)
Published 2025-06-01“…The resulting variant sets were evaluated in the context of nectar volume quantitative trait loci (QTL) mapping in sunflower (Helianthus annuus L.). …”
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6858
Production of recombinant norovirus VP1 protein and its antigenic and immunogenic properties
Published 2024-11-01“…Computer analysis of nucleotide and amino acid sequences, molecular cloning, polymerase chain reaction, electrophoresis of nucleic acids in agarose gel and proteins in polacrylamide gel, affinity chromatography, enzyme immunoassay. …”
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6859
Biocontrol Potential and Growth-Promoting Effects of Freshwater Trichoderma Strains against Plant Pathogenic Fungi in Red Pepper
Published 2025-06-01“…Forty-four Trichoderma strains isolated from freshwater environments were evaluated for their biocontrol potential against Phytophthora capsici and Fusarium solani, as well as for their siderophore production, phosphate solubilization, and enzymatic activities. …”
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6860
Mechanism and Efficacy of Etanercept in Treating Autoimmune-like Manifestations of Coronavirus Disease 2019 in elderly individuals
Published 2025-05-01“…This study aimed to evaluate the effects of etanercept, a TNF inhibitor, in elderly individuals with COVID-19 through observational analysis of compassionate use cases. …”
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