Anti-Inflammatory Effects of <i>Weissella cibaria</i> SDS2.1 Against <i>Klebsiella pneumoniae</i>-Induced Mammary Gland Inflammation by Meiyi Ren, Tianxiong Jin, Jingdi Tong, Deyuan Song, Qinna Xie, Xiaohan Li, Yan Li, Kangping Liu, Jian Gao, Mingchao Liu, Jia Cheng

“…The safety of <i>W. cibaria</i> SDS2.1 was assessed through comprehensive analyses, including antibiotic resistance profiling, hemolysis assays, cell cytotoxicity tests, and whole-genome sequencing. Furthermore, its ability to protect against cellular and tissue damage caused by <i>K. pneumoniae</i>-induced mastitis was evaluated using both in vitro and in vivo models. …”
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Intrapleural dual blockade of IL-6 and PD-L1 reprograms CAF dynamics and the tumor microenvironment in lung cancer-associated malignant pleural effusion by Qinpei Cheng, Xueying Zuo, Zimu Wang, Wanjun Lu, Yuxin Jiang, Jiaxin Liu, Xinying Li, Qiuli Xu, Suhua Zhu, Xin Liu, Yong Song, Ping Zhan, Tangfeng Lv

“…This study investigates the role of IL-6 in regulating immune suppression and tumor progression in MPE and evaluates the efficacy of dual IL-6 and PD-L1 blockade. …”
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Optimized Production of Virus-like Particles in a High-CHO-Cell-Density Transient Gene Expression System for Foot-and-Mouth Disease Vaccine Development by Ana Clara Mignaqui, Alejandra Ferella, Cintia Sánchez, Matthew Stuible, Romina Scian, Jorge Filippi, Sabrina Beatriz Cardillo, Yves Durocher, Andrés Wigdorovitz

“…We further tested the system’s capacity to express different serotypes and chimeric constructs, incorporating VP1 sequences from various FMDV strains. Immunogenicity was evaluated in swine using VLPs from the A2001 Argentina strain as a model. …”
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Molecular characterization of heavy metal-tolerant bacteria and their potential for bioremediation and plant growth promotion by Saira Abbas, Saira Abbas, Sobia Zulfiqar, Muhammad Arshad, Nauman Khalid, Nauman Khalid, Amjad Hussain, Amjad Hussain, Iftikhar Ahmed

“…The biosorption potential of 23 phylogenetically diverse strains was evaluated. Molecular identification was carried out through 16S rRNA gene sequencing, and plant growth-promoting genes (acdS and nifH) were screened. …”
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Integrative snRNA‐seq, molecular docking and dynamics simulations identifies Lasmiditan as drug candidate for Alzheimer's disease by Martin Nwadiugwu, Md Selim Reza, Boluwatife Afolabi, Demetrius M. Maraganore, Hui Shen, Hongwen Deng

“…Methods Multi‐cohort single‐nucleus RNA sequencing (snRNA‐seq) data from the prefrontal cortex were analysed to identify DERs. …”
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Chamomile Tincture and Lidocaine Hydrochloride Gel Ameliorates Periodontitis: A Preclinical Study by Jiahui Sun, Huiyi Wang, Junhong Xiao, Qiudong Yang, Heyu Liu, Zhengkun Yang, Yuqi Liu, Xin Huang, Liu Yang, Li Ma, Zhengguo Cao

“…Clinical, micro-computed tomography (micro-CT), biological, and histological evaluations were performed, focusing on osteoclastogenesis, osteogenesis, and inflammatory cytokine production. …”
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Identification and Antibacterial Characterization of Endophytic Fungi from Artemisia sieberi by Ibtisam Mohammed Ababutain, Sahar Khamees Aldosary, Amal Abdulaziz Aljuraifani, Azzah Ibrahim Alghamdi, Amira Hassan Alabdalall, Eida Marshid Al-Khaldi, Sumayh A. Aldakeel, Noor B. Almandil, Sayed AbdulAzeez, J. Francis Borgio

“…Antibacterial activity of the ethyl acetate extract was evaluated using well diffusion method on the selected isolate. …”
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Dual roles of IRE1α inhibition in reversing mitochondrial ROS-induced CD8+ T-cell senescence and exerting direct antitumor effects in multiple myeloma by Jingjing Wang, Jian Hou, Junying Wang, Zhiqiang Liu, Mengping Chen, Yike Wan, Honghui Huang, Fajun Nan

“…The effects of XBP1s and SLC38A2 on mitochondrial reactive oxygen species (mtROS) were evaluated by flow cytometry under loss-of-function experiments. …”
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Immunodynamic axis of fibroblast-driven neutrophil infiltration in acute pancreatitis: NF-κB–HIF-1α–CXCL1 by Qiang Wang, Xiao Zhang, Chenglong Han, Zhenyi Lv, Yi Zheng, Xuxu Liu, Zhiwei Du, Tianming Liu, Dongbo Xue, Tao Li, Liyi Wang

“…An AP model was induced by cerulein, and a control group was set up. Single-cell sequencing technology was used to reveal the cell atlas of AP pancreatitis tissue. …”
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The Impact of FSHR Polymorphisms (rs6165 and rs6166) on Ovarian Response to Stimulation in Infertile Women with Diminished Ovarian Reserve by Hoang TTT, Trinh ST, Nguyen NN, Ho MN, Pham MD, Hoang NT, Trieu ST, Ho HS

“…FSHR rs6165 and rs6166 were genotyped by Next-Generation Sequencing (NGS) assays, with Sanger sequencing for validation. …”
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Ralationship between polymorphisms and diplotypes of HLA-G 3’UTR and fetuses with abnormal chromosomes or unexplained pregnancy loss (UPL) by Danping Xu, Yiyang Zhu, Jun Wang, Heqin Guan, Xiuzhen Shen

“…The classification and regression tree (CART) analysis was used to evaluate the role of HLA-G diplotypes in predicting fetal outcomes. …”
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Study on immunogenicity of recombinant ferritin hemagglutinin of canine distemper virus by Dongyu Liu, Bing Liu, Jinling Guo, Yanan Zhao, Dandan Yang, Yudie Zhang, Congmei Wu, Yuhe Yin

“…Methods In this study, H protein sequences were analyzed by conservation analysis and prediction of multiple immune cell epitopes, three possible epitope sequences were identified. …”
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Promoter demethylation of cerebellin 2 by ten-eleven translocation 3 contributes to peripheral sensitization in trigeminal neuropathic pain of mice by Xin-Ying Guan, Bao-Tong Yuan, Meng-Na Li, Tian Wang, Lin-Peng Zhu, Si-Yuan Song, Lu-Lu Ji, Yong-Jing Gao, Ling-Jie Ma

“…DNA methylation of Cbln2’s promoter region was examined using methylation-specific PCR (MSP) and bisulfite sequencing PCR (BSP). Neuronal excitability was assessed through whole-cell patch-clamp recordings. …”
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Correlation of intestinal bacteria, fungi and dietary nutrient intake in NAFLD patients with spleen deficiency syndrome by Guiru Lin, Wanyi Ou, Jianmei Yang, Dongliang Chen, Yuanfei Wang, Aiping Wu, Lilian Gao, Wan Qu, Chenli Lin, Chenli Lin, Yinji Liang, Yinji Liang

“…The current study aimed to investigate the interrelationships of intestinal bacteria, fungi and dietary nutrient intake in NAFLD patients with SDS.MethodsThe NAFLD TCM Patient Reported Outcome (PRO) Scale was administered to evaluate the TCM clinical symptoms of NAFLD patients. …”
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Identification of biomarkers for Laryngeal squamous cell carcinoma through Mendelian randomization and integrated bioinformatics analysis by Pengjian Zhang, Weizhang Chen, Kai Chen, Yuanhang Ye, Weijun Wu

“…Additionally, copy number variation (CNV) data were retrieved from the UCSC Xena database, and single-cell RNA sequencing (scRNA-seq) data from two LSCC samples were obtained from the GSE150321 dataset. …”
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Ultrasound-Mediated Non-Specific Splenic Immunopotentiation to Elicit Broad-Spectrum Anti-Neoplastic Effects by Dong W, Wang G, Li S, Wang Q, Li W, Liu H, Liang Y, Zhou Z, He X, Guo W, Yuan J, Chai Y, Geng J, Li Z

“…Particularly, NK cells are much more indispensable and important in responding to FUS stimulation for cancer suppression than CD8 T cells. RNA sequencing of NK and CD8 T cells, as well as in vitro experiments revealed that FUS firstly regulated calcium-related signaling pathways to further modulate others, such as PI3K-AKT, Rap1, and Hippo pathways to promote immune cell proliferation, migration and activation to suppress cancer cell deterioration. …”
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RehabHand&#x2014;A New Physical Rehabilitation Training Dataset: Construction and Benchmark Performances of the Relevant Hand Tasks by Sinh Huy Nguyen, Hoang Bach Nguyen, Thi Thu Hong Le, Chi Thanh Nguyen, Thi Thanh Huyen Nguyen, Quynh Tho Chu, Thi Lan Le, Thanh Hai Tran, Hai Vu

“…These videos are segmented into 431 sequences that present instances of each exercise at a certain time. …”
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Microbiological aspects and clinical impact of lower lung field tuberculosis: An observational cohort study in Peru by Qi Tan, Chuan-Chin Huang, Roger Calderon, Leonid Lecca, Milagros Mendoza, Gabriela Reyes Rocha, Karen Tintaya, Ximena Tovar, Jia-Yih Feng, Sheng-Wei Pan, Yen-Han Tseng, Jhong-Ru Huang, Zibiao Zhang, Megan B. Murray

“…We used logistic regression to evaluate the associations between LLF TB and microbiological determinants and treatment outcomes. …”
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Dinuclear Gallium(III) Complex With 1,3-Propanediamine-N,N′-Diacetate: Structural Characterization, Antimicrobial Activity, and DNA/BSA Interactions by Bojana V. Pantović, Darko P. Ašanin, Žiko Milanović, Franc Perdih, Tatjana Ilic-Tomic, Dušanka D. Radanović, Iztok Turel, Miloš I. Djuran, Biljana Đ. Glišić

“…The antimicrobial potential of Complex 1 was evaluated alongside previously synthesized gallium(III) complexes, Na[Ga(1,3-pdta)]·3H2O (2) and Ba[Ga(1,3-pndta)]2·3H2O (3), with 1,3-pdta4− (1,3-propanediamine-N,N,N′,N′-tetraacetate) and 1,3-pndta4− ((±)-1,3-pentanediamine-N,N,N′,N′-tetraacetate), respectively. …”
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Construction of TRIF-knockout NA and BHK-21 cell lines and effect on rabies virus proliferation efficiency by Weitao HUANG, Jiaqi LI, Yao PENG, Xiangping YIN, Xiaofeng GUO, Jun LUO

“…The expanded cell populations were subsequently validated by PCR amplification, sequencing, and Western blot identification, TRIF-knockout NA and BHK-21 cell lines were established. …”
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