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6521
Gut Microbiome as a Potential Marker of Hematologic Recovery Following Induction Therapy in Acute Myeloid Leukemia Patients
Published 2025-02-01“…Conclusions Despite certain study limitations, our findings suggest that evaluating GM features could serve as a potential marker for hematologic recovery. …”
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6522
The Synergistic Mechanism of <i>Chelidonium majus</i> Alkaloids on Melanoma Treatment via a Multi-Strategy Insight
Published 2024-11-01“…Computational predictions identified the top 50 targets, involved in key signaling pathways including cell cycle regulation, and melanogenesis. RNA sequencing further elucidated that the combinatory treatment modulated a broader spectrum of differentially expressed genes, implicating crucial biological processes including cell differentiation, and tyrosinase metabolism. …”
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6523
2-Dodecyl-6-methoxycyclohexa-2,5-dien-1,4-dione alleviates liver fibrosis and improves intestinal flora and bile acid metabolism
Published 2025-05-01“…HE staining, Masson staining, and Sirius staining were used to evaluate the effect of DMDD on liver fibrosis. The Illumina sequencing platform was used to detect intestinal flora and liver transcriptome information in mouse feces, and high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) technology was used to detect bile acid content changes in mouse feces.ResultsThe results show that DMDD can mitigate liver fibrosis-induced damage in mice, potentially through the suppression of the TGF-β/Smad signaling pathway. …”
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6524
Magnetic resonance imaging of the lumbar spine: can we reach a consensus and have norms? A plea to colleagues in radiology India
Published 2025-02-01“…Thirty-eight percent did not specify the sagittal image sequencing (right-to-left or left-to-right). Eighty-five percent of the sagittal images were profiled from right to left, and 15% were profiled from left to right. …”
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6525
Severely Symptomatic Cucurbits in Croatia Dominantly Harbor a Complex of Potyviruses Including the Emerging Moroccan Watermelon Mosaic Virus
Published 2025-07-01“…These results have critical implications for cucurbit disease management, indicating the need to re-evaluate resistance claims in commercial cultivars and implement stricter phytosanitary surveillance in Croatia. …”
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6526
Genome-Wide Association Study and Genomic Prediction of Essential Agronomic Traits in Diversity Panel of Soybean Varieties
Published 2025-05-01“…The population structure analysis, based on genotyping-by-sequencing (GBS) data, revealed seven subpopulations within the panel and significant gene flows among these subpopulations. …”
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6527
Refining prognostic stratification of atypical meningiomas: significance of chromosome 1p deletion and brain invasion
Published 2025-03-01“…The accuracy of FISH was validated by comparison with next-generation sequencing (NGS) results. Chromosome 1p deletion was significantly associated with parafalcine/tentorial location, high mitotic index, recurrence, and shorter recurrence-free survival (RFS). …”
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6528
Association of Active Human Herpesvirus-6, -7 and Parvovirus B19 Infection with Clinical Outcomes in Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Published 2012-01-01“…Viral genomic sequences were detected by PCR, virus-specific antibodies and cytokine levels—by ELISA, HHV-6 variants—by restriction analysis. …”
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6529
Rice Grain Storage Reduces Antibiotic Resistance Risks and Pathogens Through Enrichment of Antimicrobial Metabolites
Published 2025-01-01“…Metagenomic sequencing of rice grains stored for 1–3 years showed a decline in both ARGs and pathogens with increasing storage duration. …”
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6530
Mitochondrial Genetic Mutations in the Pale Grass Blue Butterfly: Possible DNA Damage via the Fukushima Nuclear Accident and Real-Time Molecular Evolution
Published 2025-04-01“…The pale grass blue butterfly <i>Zizeeria maha</i> has been used to evaluate the biological effects of the Fukushima nuclear accident in 2011. …”
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6531
A biofilm-targeting lipo-peptoid to treat Pseudomonas aeruginosa and Staphylococcus aureus co-infections
Published 2025-06-01“…Antimicrobial peptides and their synthetic analogues, peptoids, which target bacterial cell membranes as well as intracellular components, offer potential solutions. We evaluated the biological activities of novel peptoids TM11-TM20, which include an additional charged NLys residue, against multidrug-resistant Pseudomonas aeruginosa and Staphylococcus aureus, both in vitro and in vivo. …”
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6532
Generation of transchromosomic mice harboring HLA-A/B/C and human B2M via mouse artificial chromosome and triple BAC integration
Published 2025-07-01“…Bacterial artificial chromosomes (BACs) that carry human genomic sequences with regulatory elements enable the expression of transgenes at physiological levels in vivo. …”
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6533
LncRNA938/ TAF9/TTK axis promotes EMT and serves as a therapeutic target in hepatoblastoma
Published 2025-08-01“…Methods Bioinformatic analysis was performed using sequencing datas to evaluate clinical diagnostic and prognostic values of molecules. …”
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6534
Identification of Aspergillus westerdijkiae and its potential risk of Ochratoxin A synthesis in Cannabis inflorescences
Published 2024-03-01“…To determine mycotoxin formation, the genome of A. westerdijkiae was sequenced using the Illumina Novaseq platform in South Korea. …”
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6535
The effect of prolonged G-quadruplex stabilization on the functions of human cells
Published 2025-06-01“…Abstract Guanine-rich DNA sequences have a propensity to form G-quadruplex structures. …”
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6536
FetalMovNet: A Novel Deep Learning Model Based on Attention Mechanism for Fetal Movement Classification in US
Published 2025-01-01“…To evaluate FetalMovNet, we construct a new dataset containing fetal movements in US across seven different anatomical structures-head, body, arm, hand, heart, leg, and foot. …”
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6537
Human papillomavirus detection in Moroccan patients with bladder cancer
Published 2013-08-01“…The aim of the present study is to evaluate whether HPV have an etiological role in bladder carcinogenesis among Moroccan patients. …”
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6538
Revealing the Absence of Microbiota in Hypertrophic Mucosa of Inferior Turbinate
Published 2025-03-01“…Methods and Results: This prospective and cross-sectional study evaluated microbiota in hypertrophic inferior turbinate mucosa. …”
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6539
Machine learning model for early diagnosis of breast cancer based on PiRNA expression with CA153
Published 2025-08-01“…A serum tri-piRNA signature (piR-139966, piR-2572505, piR-2570061) was selected via piRNA sequencing, validated by qPCR, and then analyzed in combination with related clinical factors. …”
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6540
Harnessing electroacupuncture: a promising strategy against sleep deprivation-exacerbated post-cardiac arrest brain injury
Published 2025-08-01“…This study investigated the mechanisms by which SD exacerbates PCABI and evaluated the neuroprotective efficacy of electroacupuncture (EA). …”
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