Integrating necroptosis into pan-cancer immunotherapy: a new era of personalized treatment by Yan Gao, Sheng Chen, Lei Li

“…MethodsA comprehensive pan-cancer analysis was performed using bulk RNA sequencing data to develop a necroptosis-related gene signature, termed Necroptosis.Sig. …”
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Securing Automotive Networks from DoS and Fuzzy Attacks with Optimized LSTM Models by W. Beniel Dennyson, C. Jothikumar

“…The model’s efficacy is demonstrated by evaluating various cyber-attacks from the Car-Hacking dataset. …”
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CYCLONE: recycle contrastive learning for integrating single-cell gene expression data by Han Ji, Xinwei He, Hongwei Li

“…Abstract Background Combining single-cell transcriptome sequencing results from several batches reduces batch effect, which improves our understanding of cellular identity and function. …”
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The Effect of Differentiation of Human Dental Pulp Stem Cells to Glial Cells on the Sensory Nerves of the Dental Pulp by Yan Liu, Yuxi Zou, Xinxin Liu, Yushan Wang, Jing Sun, Changyong Yuan, Penglai Wang

“…Simultaneous culture experiments were conducted to evaluate trigeminal neuron growth in the presence of SC-DPSCs. …”
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Subolesin gene structure and mRNA isoform diversity in South African R. microplus ticks: Relevance for understanding subolesin-based tick vaccines by Elsje Christine Rabie, Christine Maritz-Olivier

“…The mechanism behind the observed efficacy remains elusive and may be due to various isoforms being produced in tick cells. By means of RNA sequencing and mapping to the annotated genome of R. microplus, this study confirms the presence of a single subolesin gene along with four distinct transcripts, resulting in three protein variants. …”
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Synergistic effects of Rhizobium, Bacillus and Arbuscular Mycorrhizal fungi on enhancing cotton growth by Tasleem Sultana, Pavan Kumar Pindi

“…Microbial identification was performed using 16S rRNA gene sequencing. Biochemical evaluations of consortium-inoculated plants included measurements of protein, sugar, proline, and chlorophyll levels, along with IAA quantification. …”
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Genetic testing confirmed osteopetrosis with initial presentation of nystagmus by Kai-Yen Chiu, Yu-Yang Lin, Yao-Lin Liu, Ni-Chung Lee, Tzu-Hsun Tsai

“…The patient is currently being evaluated for possible hematopoietic stem cell transplantation. …”
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Reliable investigation of DNA methylation using Oxford nanopore technologies by Raj Doshi, Evan Kinnear, Sujan Chatterjee, Prasun Guha, Qian Liu

“…We also explored different methods to calculate coverage and methylation percentages. Our evaluations provide valuable recommendations for cross-ONT-chemistry methylation analysis and suggest better practices for robust methylation investigation.…”
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A hybrid framework of generative deep learning for antiviral peptide discovery by Huynh Anh Duy, Tarapong Srisongkram

“…The performance of the WGAN-GP model was comprehensively evaluated, confirming its ability to produce diverse and functional peptide sequences. …”
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SERPINA1 is a new frontier in cancer immunotherapy and drug targeting by pan-cancer analysis by Chen Fu, Yanyun Hu, Lei Yang, Weifeng Sun

“…The relationship between SERPINA1 expression and immune and drug sensitivity was also analyzed. Single-cell sequencing was used to validate the function and immunity in different cancers. …”
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Metagenomics as a Transformative Tool for Antibiotic Resistance Surveillance: Highlighting the Impact of Mobile Genetic Elements with a Focus on the Complex Role of Phages by Nikoline S. Olsen, Leise Riber

“…This review explores the potential of metagenomics, a sequenced-based approach to analyze entire microbial communities without the need for cultivation, as a transformative and rapid tool for improving AMR surveillance strategies as compared to traditional cultivation-based methods. …”
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Assessment of MRI Issues at 3 Tesla for a New Metallic Tissue Marker by Charlotte M. Cronenweth, Frank G. Shellock

“…MRI was performed at a relatively high specific absorption rate (whole body averaged SAR, 2.9-W/kg). MRI artifacts were evaluated using T1-weighted, spin echo and gradient echo pulse sequences. …”
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The use of artificial intelligence-based Siamese neural network in personalized guidance for sports dance teaching by Yi Xie, Yao Yan, Yuwei Li

“…The GCN module is responsible for extracting spatial features from the skeletal graph, while the SNN module evaluates the similarity between different skeletal sequences by comparing their features. …”
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Embedding and classifying test execution traces using neural networks by Foivos Tsimpourlas, Gwenyth Rooijackers, Ajitha Rajan, Miltiadis Allamanis

“…The classification accuracy of this approach is evaluated using subject programs from different application domains—1. …”
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Using Complexity and Spectral Analyses of Noninvasive LDF Signals in Patients with Metabolic Syndrome by Hsin Hsiu, Hsiao-Feng Hu, Yaw-Wen Chang

“…Beat-to-beat analysis was performed to obtain the mean blood flow (DC), and then approximate entropy (ApEn) values for the 10-minute DC sequences (DC_ApEn) were calculated to evaluate the signal complexity. …”
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Oncogene-driven lung cancer in the era of radiogenomics: current evidence and future developments by James Ryan, John Kavanagh, Niamh Coleman

“…In oncogene-driven lung cancer, next-generation sequencing (NGS) has uncovered actionable oncogenes such as EGFR, KRAS, ALK, BRAF, MET, HER2, and fusions in ROS1, and NTRK, which have revolutionized the management and outcomes of patients with these alterations. …”
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Performance of routine surveillance diagnostics of external ventricular drain-associated infections in a critical care setting: a retrospective cohort study by Marcus Ståhlberg, Jonas Blixt, Christer Mehle, Viveca Hambäck Hellkvist, Christian G. Giske, Eddie Weitzberg, David W. Nelson

“…We identify a large clinical problem with consequences on both a individual and population level, and recommend that future research focus on evaluating new techniques, such as fast bedside sequencing methods.…”
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Innate immune pathway activation to modulate mesenchymal stromal cell (MSC) interactions with synovium and cartilage by Peter Linde, Lyndah Chow, Isabella Sabino, Zoë Williams, Renata Impastato, Steven Dow, Lynn Pezzanite

“…IntroductionMesenchymal stromal cells (MSCs) have been evaluated as a local therapeutic option to treat osteoarthritis (OA) with conflicting clinical results. …”
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Pyroptosis of MCF7 Cells Induced by the Secreted Factors of hUCMSCs by Yang Jiao, Hongbo Zhao, Guodong Chen, Xiongbo Sang, Luhan Yang, Zongliu Hou, Wei Si, Bingrong Zheng

“…We evaluated the morphological changes, cell viability, cell cycle, apoptosis, DNA fragmentation, and interleukin-1β (IL-1β) secretion of CM-exposed MCF7 cells. …”
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Real-time quantitative PCR method for assessing wheat cultivars for resistance to Zymoseptoria tritici by Tika B. Adhikari, Boovaraghan Balaji, Stephen B. Goodwin

“…Furthermore, environmental factors and variations in disease-scoring systems among evaluators add to the complexity. To address these issues and quantify fungal growth during the initial stages of infection, we developed a real-time quantitative polymerase chain reaction (qPCR) method to monitor the T. aestivum - Z. tritici pathosystem.MethodsThe assay used specific primers designed from ß-tubulin gene sequences of Z. tritici to quantify fungal DNA in susceptible and resistant wheat cultivars and segregating recombinant-inbred lines (RILs) that were inoculated at seedling and adult-plant stages with low or high concentrations of inoculum. …”
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