-
6241
Distribution and phenotypic effect of Wolbachia in natural population of Indian Drosophila
Published 2025-01-01“…Methods: The distribution and strain identification of Wolbachia was done by PCR and Sanger sequencing method in Indian Drosophila host species. …”
Get full text
Article -
6242
Paternal microbiota manipulation influences offspring microbial colonization and development in a sex role-reversed pipefish
Published 2025-08-01“…After pregnancy, the microbiota of developing offspring was characterized using 16 S rRNA sequencing of the V3-V4 region. Paternal antibiotic and spike treatments influenced the microbial composition of the brood pouch and offspring microbiome development. …”
Get full text
Article -
6243
Recombinase-mediated reprogramming and dystrophin gene addition in mdx mouse induced pluripotent stem cells.
Published 2014-01-01“…We next used Bxb1 integrase to add the therapeutic full-length dystrophin cDNA to the iPSC in a site-specific manner. Unwanted DNA sequences, including the reprogramming genes, were then precisely deleted with Cre resolvase. …”
Get full text
Article -
6244
Study protocol for a multi-center stepped-wedge cluster randomized trial to explore the usability and outcomes among young people living with HIV in Kiambu and Kirinyaga counties o...
Published 2025-01-01“…The primary outcome will be patient activation, with secondary outcomes including self-reported adherence, social engagement and viral suppression. We will also evaluate the portal's functionality, usability, fidelity, and costs. …”
Get full text
Article -
6245
Integrated deep network model with multi-head twofold attention for drug–target interaction prediction
Published 2025-06-01“…This model leverages convolutional and recurrent neural networks to extract both local and sequential features from drug molecular structures and target protein sequences. The MHTA mechanism enhances the model’s ability to focus on different aspects of drug and target features independently, effectively capturing intricate interaction patterns. …”
Get full text
Article -
6246
The saNeuroGut Initiative: Investigating the Gut Microbiome and Symptoms of Anxiety, Depression, and Posttraumatic Stress
Published 2025-01-01“…Methods: Participants completed validated, online self-report questionnaires to evaluate symptoms of state anxiety, trait anxiety, depression, and PTSD. …”
Get full text
Article -
6247
A Satisfaction Study of Waterfront Public Spaces in Winter Cities from a Demand Perspective: A KANO-IPA Model Analysis Based on Northeastern China
Published 2025-01-01“…We used the KANO model to classify the attributes of spatial demand indicators, then applied IPA analysis to evaluate them, and finally calculated priority indices to quantify their priority sequences. …”
Get full text
Article -
6248
Melanoma genomics – will we go beyond BRAF in clinics?
Published 2024-09-01“…Abstract In the era of next-generation sequencing, the genetic background of cancer, including melanoma, appears to be thoroughly established. …”
Get full text
Article -
6249
A Long-Tail Fault Diagnosis Method Based on a Coupled Time–Frequency Attention Transformer
Published 2025-05-01“…To capture dependencies in long sequences, a multi-head self-attention mechanism is then implemented in the time domain. …”
Get full text
Article -
6250
Quantifying indoor fungal aerosol levels in slums: implications for public health
Published 2025-05-01“…Six different fungal species were isolated, Aspergillus being the predominant one, and their sequences were submitted in GenBank with Accession nos. …”
Get full text
Article -
6251
Virological characterization of a new isolated strain of Andes virus involved in the recent person-to-person transmission outbreak reported in Argentina.
Published 2025-06-01“…The pathogenicity and transmissibility potential of ARG-Epuyén were evaluated in hamsters, the only animal model for Hantavirus Pulmonary Syndrome. …”
Get full text
Article -
6252
Grammatical Processing in Schizoprenia: Analysis on Sentence Structure
Published 2022-03-01“…The narrative skills of the subjects in the study were evaluated with four oral expression tests, which were narrative picture test, story picture sequencing test, semi-structured speech test, and free speech test. …”
Get full text
Article -
6253
A new approach combining CNN, RNN, and an improved Otsu threshold method for detecting hand gestures in people with thumb finger size problems and hand tremors
Published 2025-03-01“…The performance of the novel Otsu method has been evaluated and compared using accuracy and sensitivity metrics, yielding significant results.…”
Get full text
Article -
6254
Characterization of the salivary microbiome of adults with inflammatory bowel disease
Published 2025-12-01“…This study aimed to evaluate the oral microbiome of adults with IBD and of matched controls.Methods Saliva samples and data were obtained from a Canadian population cohort (n = 320). …”
Get full text
Article -
6255
Effect of enhanced early life nutrition on the M. longissimus thoracis et lumborum transcriptome of crossbred beef heifer calves
Published 2025-07-01“…This study aimed to evaluate the impact of enhanced dietary intake during early calf-hood on the transcriptional profile of skeletal muscle tissue. …”
Get full text
Article -
6256
A Complex Clinical Situation in Polycystic Ovary Syndrome: HAIR-AN Syndrome ‘‘Case Report’’
Published 2025-01-01“…We used next-generation sequencing (NGS) to screen 70 genes for mutation and identify relevant genetic variations. …”
Get full text
Article -
6257
Metabolomic and transcriptomic analyses of drought resistance mechanisms in sorghum varieties
Published 2025-07-01“…To this end, this study evaluated the phenotypes of two sorghum varieties (GL98 and GL220) under drought stress and normal conditions, and sequenced their transcriptomes and metabolomes. …”
Get full text
Article -
6258
Can <i>Caenorhabditis elegans</i> Serve as a Reliable Model for Drug and Nutraceutical Discovery?
Published 2025-05-01“…<i>Caenorhabditis elegans</i> has proved to be a valuable model as a result of its genetic and physiological similarities to higher organisms, fully sequenced genome, short life cycle, and transparency. …”
Get full text
Article -
6259
Automatic mouse ultrasound detector (A-MUD): A new tool for processing rodent vocalizations.
Published 2017-01-01“…This algorithm improved the efficiency of processing USV files, as it was 4-12 times faster than manual segmentation, depending upon the size of the file. We evaluated A-MUD error rates using manually segmented sound files as a 'gold standard' reference, and compared them to a commercially available program. …”
Get full text
Article -
6260
Improving UAV-Based Detection of Low-Emission Smoke with an Advanced Dataset Generation Pipeline
Published 2025-03-01“…The proposed method was evaluated using a dataset of 634 stabilized UAV video sequences (10 s each), covering diverse environmental conditions, including winter scenes and oblique views. …”
Get full text
Article