Impaired Sequential Working Memory in Patients With Young Onset Parkinson's Disease by Guanyu Zhang, Shuo Zhang, Zhenzhen Zhao, Jinghong Ma, Piu Chan, Zheng Ye

“…Objectives The aim of this study is to evaluate the sequential working memory in patients with YOPD. …”
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Integrated transcriptome profiling and in vitro analysis reveals MLN4924’s role in inducing ferroptosis in acute myeloid leukemia by Jinli Jian, Yuancheng Guo, Xiao Tang, Long Zhao, Bei Liu

“…In vivo efficacy was evaluated in NOD/SCID mice bearing AML xenografts treated with MLN4924, followed by tumor tissue analysis of GSH and Fe2+ levels, immunohistochemistry (IHC), and Western blotting for SLC7A11/GPX4 axis components.Results: Transcriptome sequencing and bioinformatics analyses identified SLC7A11 and GPX4 as key MLN4924 target genes, both of which are glutathione-related proteins. …”
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Detection of Asymptomatic Sickle Cell Hemoglobin Carriers and Fetal Hemoglobin Regulating Genetic Variants in African Descendants from Oaxaca, Mexico by María De Los Ángeles Romero-Tlalolini, Sergio Roberto Aguilar-Ruiz, Rafael Baltiérrez-Hoyos, Jaime Vargas-Arzola, Luis Alberto Hernández-Osorio, Verónica Rocío Vásquez-Garzón, Héctor Ulises Bernardino-Hernández, Honorio Torres-Aguilar

“…SNVs in the hemoglobin subunit beta gene (HBB) were identified by the β-globin mutation detection assay (β-GMDA) and ARMS-PCR, respectively, and validated by Sanger sequencing. The association between genotypes and HbF concentrations was evaluated using Spearman’s correlation coefficient. …”
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Biosynthesis and Characterization of Silver Nanoparticles Produced by Phormidium ambiguum and Desertifilum tharense Cyanobacteria by Amira L. Hanna, Hayam M. Hamouda, Hanan A. Goda, Mahmoud W. Sadik, Farahat S. Moghanm, Adel M. Ghoneim, Muneefah A. Alenezi, Sultan F. Alnomasy, Pravej Alam, Tarek R. Elsayed

“…Therefore, these Ag-NPs were characterized and evaluated for antibacterial and antioxidant activity. …”
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Characterization of Bacillus velezensis LH023 Isolated From Grass Carp Intestines and Its Beneficial Effects on Growth, Immunity, and Gut Microbiota in Aquaculture by Lihan Liu, Jiaming Huang, Yiling Huang, Zhendong Qin, Fubin Zhang

“…In this study, Bacillus velezensis was isolated from the intestines of grass carp and identified as LH023 via 16S rRNA sequencing and morphological analysis. To evaluate its potential as a feed additive in aquaculture, LH023 was supplemented at two concentrations (107, 7 × 107 and 108, 7 × 108 CFU/g) in a 6-week feeding trial, alongside a control group. …”
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Isolation of phages active against Pseudomonas aeruginosa and Staphylococcus epidermidis from human breast milk, an underexplored microbiome by Dr Steven De Soir, Dr. Jeroen Waegemans, Professor Rob Lavigne, Dr. Jean-Paul Pirnay, Dr. Maya Merabishvilli, Professor Jeremy Barr, Professor Françoise Van Bambeke, Dr. Daniel De Vos

“…Phage characterization was performed with genetic sequencing, host range evaluations along with metabolic assays (Omnilog Biotyper) delineating possible therapeutic potential of the isolated phages. …”
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JAK2 inactivating mutations promotes endometrial cancer progression by targeting HIF-1α by Zheng Chen, Xuan Zheng, Weijian Zeng, Juan Wang, Qin Lin

“…Methods The genetic alterations of JAK2 in different cancer types were explored using sequencing dataset deposited at TCGA database. JAK2 mutations were detected in EC formalin-fixed paraffin-embedded (FFPE) samples using Sanger sequencing. …”
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Informative value of whole-body magnetic resonance imaging with diffusion-weighted images for the detection of bone marrow infiltration in patients with multiple myeloma (literatur... by N. S. Lutsik, L. P. Mendeleeva, G. A. Yatsik

“…This article provides an overview of the possibilities of MRI with anatomical sequences and with DWI for diagnosing, monitoring and evaluating the response to treatment in patients with MM. …”
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Circ‐myh8/KAT7 Affects PANoptosis in Pulmonary Arterial Smooth Muscle Cells: Involvement of Super‐Enhancers in FOSL2 Expression by Jingya Zhang, Xinru Wang, Xu Wang, Songyue Li, Jianli Hou, Yibin Zhang, Xinyue Song, Shukun Cao, Ya Xu, Jing Qi, Baoshan Zhao, Xiaodong Zheng, Yan Xing

“…Methods Chromatin immunoprecipitation (ChIP)‐sequencing was integrated with RNA sequencing to identify SE‐regulated target genes in hypoxic PASMCs. …”
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Changes in texture and lignin during different developmental stages of mulberries and transcriptome analysis by WANG Binbin, DAI Xianglong, DU Kaiqun, SHEN Zixin, WANG Hui, GAO Yanxia

“…The texture indicators (hardness, adhesiveness, cohesiveness, elasticity, gumminess, and chewiness) were measured using a texture analyzer, lignin content was determined using the concentrated sulfuric acid method, and transcriptome sequencing was performed. The QRT-PCR experiments were conducted, and redundancy analysis (RDA) was used to analyze the correlation between lignin, berry texture, and lignin biosynthesis-related genes, as well as to evaluate the relationships among various factors. …”
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Molecular Identification of Endophytic Bacteria Isolated From Allium cepa L. Waste as Antibiofilm Agent Against S.mutans by Ekajayanti Kining, Dian Firdiani, Sogandi, Muh. Achyar Ardat

“…Morphological and Gram-staining analyses were conducted alongside molecular identification through 16S rRNA sequencing. Antibacterial and antibiofilm assays were performed to evaluate the biological activity of isolate EA1. …”
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The nitrogen-fixing strains of Enterobacter cloacae isolated from mung bean (Vigna radiata L.) enhance mung bean nodulation and growth by Awoke Zenebe, Fikadu Hailemichael, Asnake Beshah, Ruya Giray, Ebru Toksoy Oner, Asmamaw Tesfaw

“…This study aimed to isolate, characterize and evaluate nitrogen-fixing Enterobacter strains derived from mung bean samples collected from four districts in Ethiopia. …”
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The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. by Benjamin F Voight, Hyun Min Kang, Jun Ding, Cameron D Palmer, Carlo Sidore, Peter S Chines, Noël P Burtt, Christian Fuchsberger, Yanming Li, Jeanette Erdmann, Timothy M Frayling, Iris M Heid, Anne U Jackson, Toby Johnson, Tuomas O Kilpeläinen, Cecilia M Lindgren, Andrew P Morris, Inga Prokopenko, Joshua C Randall, Richa Saxena, Nicole Soranzo, Elizabeth K Speliotes, Tanya M Teslovich, Eleanor Wheeler, Jared Maguire, Melissa Parkin, Simon Potter, N William Rayner, Neil Robertson, Kathleen Stirrups, Wendy Winckler, Serena Sanna, Antonella Mulas, Ramaiah Nagaraja, Francesco Cucca, Inês Barroso, Panos Deloukas, Ruth J F Loos, Sekar Kathiresan, Patricia B Munroe, Christopher Newton-Cheh, Arne Pfeufer, Nilesh J Samani, Heribert Schunkert, Joel N Hirschhorn, David Altshuler, Mark I McCarthy, Gonçalo R Abecasis, Michael Boehnke

“…Here, we describe the Metabochip and its component SNP sets, evaluate its performance in capturing variation across the allele-frequency spectrum, describe solutions to methodological challenges commonly encountered in its analysis, and evaluate its performance as a platform for genotype imputation. …”
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The coconut palm in China: distribution, germplasm, and sustainable development through genomic and biotechnological approaches by Zhihua Mu, Hui Peng, Senarath P. N. C. Jayarathna, ⁠Mallawa T. N. Indrachapa, Chongxi Yang, Shuya Yang, Junjie Zhou, Weiqi Xu, Yue Jiang, ⁠Vijitha R. M. Vidhanaarachchi, Yong Xiao, Jie Luo

“…Although the coconut industry in China is relatively small, there is increasing emphasis on identifying and evaluating coconut germplasm through advanced genomic tools. …”
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Effects of dietary supplementation with a microalga (Schizochytrium sp.) on the hemato-immunological, and intestinal histological parameters and gut microbiota of Nile tilapia in n... by Felipe Pinheiro de Souza, Ed Christian Suzuki de Lima, Angela Maria Urrea-Rojas, Suelen Aparecida Suphoronski, César Toshio Facimoto, Jailton da Silva Bezerra Júnior, Thalita Evani Silva de Oliveira, Ulisses de Pádua Pereira, Giovana Wingeter Di Santis, Carlos Antonio Lopes de Oliveira, Nelson Mauricio Lopera-Barrero

“…Alterations in intestinal morphology were evaluated. The gut microbiota was evaluated with next-generation sequencing. …”
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Neuroprotective and probiotic potential of Lactiplantibacillus plantarum AM2 in cognitive impairment by Walid A. Lotfy, Amira M. Ali, Heba M. Abdou, Khaled M. Ghanem

“…Abstract This study aimed to isolate and characterize an acetylcholine-producing probiotic strain and to evaluate its potential anti-Alzheimer properties in D-galactose rat model. …”
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The battle against dental caries: defeating biofilm formed by bacterial isolates using vanillin and plant essential oils: in vitro and ex vivo approaches by Manar M. Ahmed, Nehal E. Yousef, Momen Askoura, Galal Yahya, Amira M. El-Ganiny

“…The antibiofilm activity of tested compounds (rose and jasmine oils, propolis, vanillin, and vinegar) was evaluated against isolates with highest biofilm-forming capacity. …”
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Demonstrating the clinical utility of genomic profiling using cerebrospinal fluid to inform management of central nervous system tumors – a meta analysis of the literature by Sakshi Khurana, Qian Nie, Kala F. Schilter, Honey V. Reddi

“…Key data fields such as DNA input, technologies used, biomarkers evaluated, types of CNS tumors, sensitivity and specificity, and performance outcomes were analyzed. …”
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Hypolipidemic Effect and Mechanism of Bifidobacterium animalis NX-6 on a Zebrafish Model of Hyperlipidemia by HE Yingxi, XU Xinzhu, LIN Shuxian, SHENG Wen, XU Suhua, GUO Lina

“…Its safety and potential benefits were evaluated at the genetic level through whole-genome sequencing. …”
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Seasonality, molecular epidemiology, and virulence of Respiratory Syncytial Virus (RSV): A perspective into the Brazilian Influenza Surveillance Program. by Lucas A Vianna, Marilda M Siqueira, Lays P B Volpini, Iuri D Louro, Paola C Resende

“…Gene G sequencing and phylogenetic reconstruction demonstrated local genetic diversity.…”
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