Hybrid peptides inspired by the RWQWRWQWR sequence inhibit cervical cancer cells growth in vitro by Natalia Ardila-Chantré, Claudia Marcela Parra-Giraldo, Yerly Vargas-Casanova, Andrea Carolina Barragán-Cardenas, Ricardo Fierro-Medina, Zuly Jenny Rivera-Monroy, Jhon Erick Rivera-Monroy, Javier Eduardo García-Castañeda

“…Some hybrid peptides exhibited significant, fast, and selective cytotoxic activity against the cancerous cells evaluated, specifically those containing sequences of anticancer peptides and cell-penetrating peptides. …”
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Genetic Variants Are Not Rare in ICD Candidates with Dilated Cardiomyopathy: Time for Next-Generation Sequencing? by Alexandra Sousa, Paulo Canedo, Manuel Campelo, Brenda Moura, Sérgio Leite, Márcia Baixia, Adriana Belo, Francisco Rocha-Gonçalves, José Carlos Machado, José Silva-Cardoso, Elisabete Martins, FATIMA Investigators

“…Molecular analysis included 15 genes (LMNA, MYH7, MYBPC3, TNNT2, ACTC1, TPM1, CSRP3, TCAP, SGCD, PLN, MYL2, MYL3, TNNI3, TAZ, and LDB3) using next-generation sequencing. Results. We evaluated 21 patients, 12 (57%) males and 9 (43%) with familial DCM, including 3 (14%) with a family history of premature unexplained SCD. …”
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Whole exome sequencing-based homologous recombination deficiency test for epithelial ovarian cancer by Ying-Cheng Chiang, Hsien-Neng Huang, Kuan-Ting Kuo, Wuh-Liang Hwu, Po-Han Lin

“…The WES-based HRD score was calculated using the scarHRD software. We first evaluated the concordance of the HRD status defined by the Myriad MyChoice CDx and then assessed the value of HRD on clinical prognosis in patients with EOC. …”
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Whole Genome Sequencing of Multidrug-Resistant Staphylococcus haemolyticus circulating in pregnant individuals in Brazil by Andre Rio Tinto, Dr Natália Costa, Dr Laura Oliveira, Prof. Sergio Fracalanzza, Prof. Lucia Teixeira, Dr Penelope Marinho, Prof. Tatiana Pinto

“…Antimicrobial susceptibility was evaluated according to CLSI. Whole genome sequencing was performed using the Illumina platform, and genomic data analysis was developed using CARD, ResFinder, PubMLST and BLAST databases. …”
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Clinical applications of and molecular insights from RNA sequencing in a rare disease cohort by Jamie C. Stark, Neta Pipko, Yijing Liang, Anna Szuto, Chung Ting Tsoi, Megan A. Dickson, Kyoko E. Yuki, Huayun Hou, Sydney Scholten, Kenzie Pulsifer, Meryl Acker, Meredith Laver, Harsha Murthy, Olivia M. Moran, Emily Bonnell, Nicole Liang, Jashanpreet Sidhu, Lucie Dupuis, Mohammad M. Ghahramani Seno, Care4Rare Canada Consortium, Marisa Chard, Rebekah K. Jobling, Jessie Cameron, Rose Chami, Michal Inbar-Feigenberg, Michael D. Wilson, David A. Chitayat, Kym M. Boycott, Lianna Kyriakopoulou, Roberto Mendoza-Londono, Christian R. Marshall, James J. Dowling, Gregory Costain, Ashish R. Deshwar

“…Abstract Background RNA sequencing (RNA-seq) is emerging as a valuable tool for identifying disease-causing RNA transcript aberrations that cannot be identified by DNA-based testing alone. …”
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WORLDWIDE GENETIC POLYMORPHISM OF CIRCUMSPOROZOITE PROTEIN IN PLASMODIUM VIVAX SEQUENCES: A SYSTEMATIC REVIEW by Marrara Pereira Sampaio, Marcelo Cerilo-Filho, Yasmin de Goés, Maria Naely Gomes Almeida, Rayanne Iane Correa, Nathália Faria Reis, Andréa Regina de Souza Baptista, Ricardo Luiz Dantas Machado

“…Out of 709 sequences analyzed, VK210 (n = 591) was the most prevalent worldwide, followed by VK247 (n = 116) and P. vivax-like (n = 2). …”
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Tracing the evolutionary pathway of SARS-CoV-2 through RNA sequencing analysis by Mostafa Rezapour, Sean V. Murphy, David A. Ornelles, Patrick M. McNutt, Anthony Atala

“…This study employed RNA sequencing (RNA-Seq) to analyze gene expression differences across multiple SARS-CoV-2 variants. …”
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Rapid inference of antibiotic susceptibility phenotype of uropathogens using metagenomic sequencing with neighbor typing by Amanda C. Carroll, Leanne Mortimer, Hiren Ghosh, Sandra Reuter, Hajo Grundmann, Karel Brinda, William P. Hanage, Angel Li, Aimee Paterson, Andrew Purssell, Ashley Rooney, Noelle R. Yee, Bryan Coburn, Shola Able-Thomas, Martin Antonio, Allison McGeer, Derek R. MacFadden

“…RASE analysis was performed on pathogen-specific reads from metagenomic sequencing. We evaluated the ability to predict (i) multi-locus sequence type (MLST) and (ii) susceptibility profiles. …”
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Impact of microbiological molecular methodologies on adaptive sampling using nanopore sequencing in metagenomic studies by Josephine Herbert, Stanley Thompson, Angela H. Beckett, Samuel C. Robson

“…As sequencing technologies continue to develop, and advances such as adaptive sampling become common techniques within the microbiological toolkit, it is essential to evaluate the benefits of such advancements to metagenomic studies, and the impact of methodological choices on research outcomes. …”
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Sleep Staging Using Compressed Vision Transformer With Novel Two-Step Attention Weighted Sum by Hyounggyu Kim, Moogyeong Kim, Wonzoo Chung

“…Automatic sleep staging is crucial for diagnosing sleep disorders, however, existing inter-epoch feature extraction schemes such as RNN-based networks or transformers often struggle with long sleep sequences due to overfitting. This study presents a novel automatic sleep staging method utilizing a pre-trained vision transformer with compression as a sequence encoder and a two-step attention to enhance the sleep-stage classification performance. …”
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MissPred: A Robust Two-Stage Radar Echo Extrapolation Algorithm for Incomplete Sequences by Ziqi Zhao, Chunxu Duan, Lin Song, Qilin Zhang, Wenda Zhu, Yi Liu

“…Existing extrapolation models typically assume complete radar echo sequences, but in practice, data loss frequently occurs due to equipment failures and communication disruptions. …”
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Time sequence of non-grain cultivated land restoration in Shandong Peninsula urban agglomeration, China by Jinhua Liu, Yuqing Wang, Zhongxiao Cong, Baokun Zhu, Keqiang Wang, Yan Zhao

“…Subsequently, a comprehensive time-sequence evaluation system was developed incorporating three key dimensions: restoration potential, urgency and agglomeration. …”
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An Optimized Dynamic Scene Change Detection Algorithm for H.264/AVC Encoded Video Sequences by Giorgio Rascioni, Susanna Spinsante, Ennio Gambi

“…This paper deals with the design and performance evaluation of a dynamic scene change detector optimized for H.264/AVC encoded video sequences. …”
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Review of 16S and ITS Direct Sequencing Results for Clinical Specimens Submitted to a Reference Laboratory by Michael Payne, Robert Azana, Linda M. N. Hoang

“…We evaluated the performance of 16S and internal transcribed spacer (ITS) region amplification and sequencing of rDNA from clinical specimens, for the respective detection and identification of bacterial and fungal pathogens. …”
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Advanced Bioluminescence Reporter with Engineered <i>Gaussia</i> Luciferase via Sequence-Guided Mutagenesis by Vinayakumar Gedi, Eun Hye Kim, Bohyun Oh, Young-Pil Kim

“…<i>Gaussia</i> luciferase (<i>G</i>Luc) is the preeminent secreted luciferase widely used in cell-based reporter assays. By employing sequence-guided mutagenesis informed by alignments of diverse copepod luciferase sequences, we identified key amino acids that significantly enhance bioluminescence (BL) intensity. …”
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Experience of implementing metagenomic next-generation sequencing in patients with suspected pulmonary infection in clinical practice by Yuting Lai, Binqi Chen, Sida Chen, Yan Shen

“…Metagenomic next-generation sequencing (mNGS) has emerged as a promising diagnostic tool for identifying pathogens responsible for pulmonary infections. …”
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Critical metals in coal and coal-bearing sequences: A comparison between China and the United States by Shifeng DAI

“…Critical metals hosted in coal and coal-bearing sequences have emerged as a cutting-edge research topic in coal geology, mineralogy, metallurgy, and mineral processing. …”
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Postcontrast Fluid-Attenuated Inversion Recovery (FLAIR) Sequence MR Imaging in Detecting Intracranial Pathology by Ajit Mahale, Shaloo Choudhary, Sonali Ullal, Merwyn Fernandes, Sonali Prabhu

“…Our study analysed FLAIR MRI sequence for evaluating postcontrast enhancement. Objectives. …”
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Haplotype-resolved chromosome-level genome sequence of Elsholtzia splendens (Nakai ex F.Maek.) by Sung Jin Moon, Sae Hyun Lee, Woo Hyun Sim, Han Suk Choi, Ju Seok Lee, Sangrea Shim

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The complete mitochondrial genome of Cenchrus fungigraminus indicates structural dynamics and sequence divergences in Poaceae family by Wentao Sheng, Wentao Sheng

“…A total of 235 dispersed, 93 simple sequence, and 38 tandem repeats were detected. Furthermore, 34 sequence fragments (17,634 bp) were transferred from the chloroplast to the mitochondria, accounting for 4.36% of the complete mitochondrial genome. …”
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