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341
Impact of metagenomics next-generation sequencing on etiological diagnosis and early outcomes in sepsis
Published 2025-04-01“…Abstract Background Clinical implications of metagenomics next-generation sequencing (mNGS) in sepsis have not been fully evaluated. …”
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342
Databank of genomic sequences of pathogenic microorganisms and its role in the implementation of epidemiological surveillance
Published 2025-01-01“…To deposit information obtained in the course of molecular genetic studies in Russia, the Virus Genome Aggregator of Russia (VGARus) databank was created.Aim. To evaluate data on the variability of genetic sequences of the Epstein-Barr virus (EBV), obtained as a result of Russian studies, and the possibility of their integration into the VGARus database forsubsequent use in epidemiological surveillance.Material and methods. …”
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343
Targeted next-generation sequencing-based detection of microsatellite instability in colorectal carcinomas.
Published 2021-01-01“…In the present study, we developed a computational method and panel markers to assess microsatellite instability (MSI) using a targeted next-generation sequencing (NGS) platform and compared the performance of our computational method, mSILICO, with that of mSINGS to detect MSI in CRCs. …”
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344
Immunomodulatory effects of PACAP sequence modifications in juvenile white shrimp Litopenaeus vannamei
Published 2024-12-01“…In this study, the immunomodulatory effects of C. gariepinus PACAP-38 and four PACAP sequence modified peptides in juvenile L. vannamei were evaluated. …”
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345
Characterization of Streptococcus pneumoniae isolates from India with special reference to their sequence types
Published 2013-02-01“…In the present study we evaluated antimicrobial susceptibilities, serotypes, and sequence types of pneumococcal isolates recovered in New Delhi, India. …”
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346
Single-cell sequencing reveals the role of SALL4 in cervical cancer development
Published 2025-07-01“…Methods Single-cell sequencing technology was utilized to analyze the cellular characteristics of cervical cancer tumor cell populations, and transcriptomic data were integrated to assess the differential expression of SALL4. …”
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347
Deciphering the Population Characteristics of Leiqiong Cattle Using Whole-Genome Sequencing Data
Published 2025-01-01“…In this study, we conducted genomic comparisons using whole-genome sequencing data from the two subgroups of Leiqiong cattle and three commercial breeds to assess their population structures. …”
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348
Clinical Utility of Next-Generation Sequencing-Based Molecular Panel in Thyroid Nodules
Published 2025-03-01“…Despite being recommended by the ATA 2015 guidelines, the utility of molecular testing in India is hindered by challenges related to availability and cost-effectiveness, thereby limiting its widespread adoption. We aimed to evaluate the clinical utility of next-generation sequencing (NGS)-based molecular testing in Indian patients with ITNs. …”
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349
A method for comparing MRI sequences of the knee for segmentation based on morphological features.
Published 2024-01-01“…<h4>Background</h4>In magnetic resonance imaging (MRI) segmentation research, the choice of sequence influences the segmentation accuracy. This study introduces a method to compare sequences. …”
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350
Exploring the impact of deubiquitination on melanoma prognosis through single-cell RNA sequencing
Published 2024-12-01“…Thus, identifying novel prognostic biomarkers and therapeutic targets is essential.MethodsWe utilized single-cell RNA sequencing data (GSE215120) from the Gene Expression Omnibus (GEO) database, preprocessing it with the Seurat package. …”
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351
Molecular sequencing and phylogenetic analysis of bioaerosols in hospital wards with different ventilation conditions
Published 2022-01-01“…., centrally air-conditioned and non-central air-conditioned) in determining bioaerosols load was evaluated by using both culture and non-culture based (Flow cytometry) approaches. …”
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352
Whole Genome Sequencing Reveals Clade‐Specific Genetic Variation in Blacklegged Ticks
Published 2025-02-01“…In this study, we performed whole genome nanopore sequencing of individual (n = 1) blacklegged ticks across their geographical range (Minnesota, Pennsylvania, and Texas) to evaluate genetic divergence among populations. …”
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353
THERAPEUTIC IMPLICATIONS OF TARGETED SEQUENCING AND miRNA-SEQ OF B CELL LYMPHOMAS
Published 2022-08-01“…Objective: Next-generation sequencing (NGS)-based approaches facilitated the identification of genomic and transcriptomic alterations associated with the development of B-cell lymphomas. …”
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354
Streamlining of Simple Sequence Repeat Data Mining Methodologies and Pipelines for Crop Scanning
Published 2024-09-01“…Over the past 50 years, DNA markers have rapidly changed, moving from hybridization-based and second-generation-based to sequence-based markers. Simple sequence repeats (SSRs) are the ideal markers in plant breeding, and they have numerous desirable properties, including their repeatability, codominance, multi-allelic nature, and locus specificity. …”
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355
Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci.
Published 2014-01-01“…By sequencing the coding sequence and 5' and 3' untranslated regions of 78 genes at 17 GWAS loci associated with one or more of six metabolic traits (serum levels of fasting HDL-C, LDL-C, total cholesterol, triglycerides, plasma glucose, and insulin), and conducting both single-variant and gene-level association tests, we obtained a more complete understanding of phenotype-genotype associations at eight of these loci. …”
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356
Juvenile Dermatomyositis Outcome Prediction Using Magnetic Resonance Imaging STIR Sequences
Published 2024-01-01“…We explored a Short Tau Inversion Recovery (STIR) sequence Magnetic Resonance Imaging (MRI) protocol as a non-invasive baseline investigation to assess the present outcome in a cohort of JDM patients. …”
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357
Dose sensitivity of MAGIC-f polymer gel using different MRI sequences
Published 2022-12-01“…This study aims to evaluate the dose sensitivity of MAGIC-f gel irradiated by high-energy photon beams, comparing quantification using different MRI sequences. …”
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358
Quantification of Lactobacillus spp. and Bifidobacterium spp. in hospitalized children with Pierre Robin Sequence
Published 2024-11-01“…Participants: Six children, one male and five females, who were hospitalized for the management of their condition, were evaluated during the first (M1) and second (M2) months of life. …”
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359
Seismic performance of K-EBF structures considering aftershock sequences and link failure
Published 2024-10-01“…Aiming at the problems that the failure of members can change the stress state of the structure, and the building may be severely damaged or even collapsed due to aftershock sequences, the effect of aftershock sequences and link failure on the seismic performance of K-eccentrically braced steel frames (K-EBF) was investigated. …”
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360
Complete Genome Characterization of Canine Adenovirus From Türkiye With Next‐Generation Sequencing
Published 2025-01-01“…To address this gap, we analysed next‐generation sequencing data obtained from our previous study to provide the complete genome sequence of the canine adenovirus‐2 strain. …”
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