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In-depth characterization of Klebsiella pneumoniae carbapenemase (KPC)-encoding plasmids points at transposon-related transmission of resistance genes
Published 2025-03-01“…Core genome multi-locus sequence typing analysis (cgMLST) identified two distinct genetic clusters: a sequence type (ST) 307 cluster (n = 5) and a ST101 cluster (n = 2). …”
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2162
Establishment of a nomogram-based prognostic model (LASSO-Cox regression) for predicting platelet storage lesions under different storage conditions
Published 2025-03-01“…Through microRNA sequencing, we identified 13 differentially expressed miRNAs with platelets storage lesions (PSLs). …”
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2163
Impact Mechanisms of Different Ecological Forest Restoration Modes on Soil Microbial Diversity and Community Structure in Loess Hilly Areas
Published 2024-11-01“…Moreover, the soil microbial diversity and community structure, functional gene diversity, and differences in the restoration modes were deeply analyzed by meta-genomic sequencing technology, and the inherent driving correlation and mechanisms among these indicators were discussed. …”
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2165
Ultrasound and genetic findings in a case series of fetuses presenting vertebral defects
Published 2025-08-01“…WES followed by Sanger sequencing validation identified a novel frameshift duplication mutation TBX6 NM_004608.4: c.989_990dup p.…”
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2166
Low Voltage Ride Through Coordination Control Strategy of DFIG with Series Grid Side Converter
Published 2025-05-01“…The present study confirms the viability of implementing positive and negative sequences of voltage separation control in the SGSC during both grid faults and steady state. …”
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2167
A Stroll Through Saffron Fields, Cannabis Leaves, and Cherry Reveals the Path to Waste-Derived Antimicrobial Bioproducts
Published 2025-07-01“…Full-proteome multiple sequence alignments across the bacterial strains were used to identify conserved, strain-specific proteins, and molecular docking simulations were applied to predict binding interactions between the most abundant compounds in the extracts and their targets. …”
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2168
The Dialogue study: Protocol for a randomized clinical trial evaluating the efficacy of virtual reality-based psychotherapy plus treatment as usual versus treatment as usual for ea...
Published 2025-01-01“…While this preliminary evidence is promising, further research is needed to evaluate the efficacy of an avatar-based intervention for eating disorders. …”
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2170
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Comparative genomic analysis of resistance and virulence genes in staphylococcus epidermidis and their impact on clinical outcome of musculoskeletal infections
Published 2025-07-01“…The logistic regression model’s performance was evaluated by Nagelkerke’s R, which resulted in 47.21%. …”
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Genetic variation in patent foramen ovale: a case-control genome-wide association study
Published 2025-01-01“…Single-nucleotide polymorphisms (SNPs) associated with PFO were further validated by Sanger sequencing and subsequently were evaluated in a validation cohort. …”
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2174
Deciphering Immunometabolic Landscape in Rheumatoid Arthritis: Integrative Multiomics, Explainable Machine Learning and Experimental Validation
Published 2025-01-01“…Mendelian randomization (MR) and mediation analyses were applied to evaluate causal relationships among plasma metabolites, immune cells, and RA. …”
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2175
Adaptive Practicing Design to Facilitate Self-Regulated Learning
Published 2025-04-01Get full text
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2176
The Role of Urinary Microbiome Analysis in the Diagnostic Approach and Management of Urinary Incontinence: A Systematic Review
Published 2025-02-01“…This systematic review aimed to evaluate the current evidence on the urinary microbiome’s role in diagnosing and managing UI, focusing on variations in microbial composition across UI subtypes. …”
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2177
A Study on the Changing Law of Bacterial Communities in the Milk of Bactrian Camels with Subclinical Mastitis
Published 2025-06-01“…However, research on shifts in milk bacterial communities following subclinical mastitis in camels is limited. We evaluated changes in bacterial communities following subclinical mastitis in Bactrian camels. …”
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Dietary <i>Pleurotus citrinopileatus</i> Polysaccharide Improves Growth Performance and Meat Quality Associated with Alterations of Gut Microbiota in Arbor Acre Broilers
Published 2024-10-01“…This study aimed to evaluate the impact of <i>Pleurotus citrinopileatus</i> polysaccharide (PCP, including PCP250, PCP500, PCP750, and PCP1000 mg/kg) on the growth performance, meat quality, and microbial composition of Arbor Acre (AA) broilers (total 180) by metabolomics and high-throughput sequencing. …”
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A novel molecular classification system for head and neck squamous cell carcinoma: predicting treatment response and metastatic potential through multi-omics analysis
Published 2025-04-01“…Methods We integrated single-cell and bulk RNA sequencing data from 59,376 cells across ten datasets using Scissor and scSTAR packages. …”
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A novel NBN germline mutation as the likely inherited etiology of various cancer types in an Iranian family
Published 2025-05-01“…Sanger sequencing and co-segregation analysis were performed for the variant’s confirmation. …”
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