Cancer Accumulation and Anticancer Activity of “CROX (Cluster Regulation of RUNX)” PIP in HER2‐Positive Gastric Cancer Evaluated by Chicken Egg Cancer Model by Tatsuya Masuda, Takayoshi Watanabe, Yasutoshi Tatsumi, Jason Lin, Kazuhiro Okumura, Toshinori Ozaki, Hiroshi Sugiyama, Yasuhiko Kamikubo

“…ABSTRACT Background We have focused on pyrrole‐imidazole (PI) polyamide compounds, which preferentially bind to their target DNA sequences. To validate our “CROX (Cluster Regulation of RUNX)” strategy, we have created a novel PI polyamide‐based inhibitor against RUNX termed Chb‐M’. …”
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Role of Magnetic Resonance Spectroscopy and Diffusion-weighted Imaging in the Evaluation of Supratentorial Brain Tumours with Histopathology Correlation at a Tertiary Care Hospital... by Kotireddy Pavan Kumar Reddy, Rajalingam Venkat Sai, R. Archana, Sarala Devi, Sunitha Bajaj, Valluru Naga Lakshmi Vaishali

“…Thus, the study aimed to evaluate the effectiveness of these non-invasive diagnostic methods in patients with suspected intracranial lesions. …”
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Production and purification of recombinant proteins VP2 and VP3 of the <i>Alongshan</i> virus of the <i>Jingmenvirus</i> group and evaluation of their immunochemical properties by Ekaterina V. Bondarenko, Elena A. Ermolaeva, Ivan S. Kholodilov, Aleksander G. Litov

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A landscape review with novel criteria to evaluate microbial drivers for cancer: priorities for innovative research targeting excessive cancer mortality in sub-Saharan Africa by Rebecca Toumi van Dorsten, Rebecca Toumi van Dorsten, Rebecca Toumi van Dorsten, Robert F. Breiman, Robert F. Breiman

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Peripheral Blood T‐Cell Receptor Repertoire Diversity as a Potential Biomarker in the Diagnosis and Treatment Evaluation of Colorectal and Lung Cancers: A Prospective Observational... by Jilong Ma, Yuanbiao Wang, Zhixin Zhang, Xinyi Cai, Xudong Xiang, Yan Chen, Fengqiong Sun, Jian Dong

“…This study aimed to evaluate the potential D50 value in the diagnosis and treatment evaluation of colorectal cancer (CRC) and nonsmall‐cell lung cancer (NSCLC). …”
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Evaluation of the Application Effects of <i>Siniperca chuatsi</i> in Biofloc Systems: A Comparative Study on the Use of Bamboo Flour and Rice Straw as Carbon Sources by Huiling Zhang, Zhaojie Deng, Shijun Chen, Xi Xiong, Wenhui Zeng, Fang Chen, Huanjiao Tan, Xuran Chen, Canmin Yang, Yuhui He, Dizhi Xie, Lian Gan

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Design and biological evaluation of substituted 5,7-dihydro-6H-indolo[2,3-c]quinolin-6-one as novel selective Haspin inhibitors by Sreenivas Avula, Xudan Peng, Xingfen Lang, Micky Tortorella, Béatrice Josselin, Stéphane Bach, Stephane Bourg, Pascal Bonnet, Frédéric Buron, Sandrine Ruchaud, Sylvain Routier, Cleopatra Neagoie

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Microbiome profiling in patients with Bladder Pain Syndrome/Interstitial cystitis by Puck Oude Elferink, Aida Javan Balegh Marand, John Heesakkers, Ellen van den Munckhof, Wilco Knetsch, Frank Martens, Mohammad Sajjad Rahnama’i, Dick Janssen

“…The small pilot that was done to evaluate microbiome stability over time in a single BPS/IC patient, showed remarkable stability of microbiome composition during a one-year follow-up.…”
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The neutrophil extracellular trap-related gene FPR1 (formyl peptide receptor 1) as a potential prognostic and therapeutic target in osteosarcoma by Shihao Li, Qiong Yuan, Yuanyuan Zhang, Haiyang Zhang

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Comparative evaluation of push-out bond strength after root perforation repair using recently introduced bioceramic and calcium silicate-based materials – An in vitro study by Gurinder Kaur, Deepak Kurup, Deepyanti Dubey, Ajit Hindlekar, Ganesh Ranganath Jadhav, Priya Mittal, Siddharth Shinde

“…Aim: This study was planned to comparatively evaluate the push-out bond strength (PBS) after perforation (PF) repair using mineral trioxide aggregate (MTA) repair high plasticity (HP), Biodentine, and EndoSequence Bioceramic (BC) root repair material (ERRM). …”
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Unveiling the heterosis pattern of modern maize breeding in Southwest China through population structure and genetic diversity analysis by Peng Ma, Hua Zhang, Hongxia Shui, Xuecai Zhang, Xiuquan Wang, Shibin Gao, Haiying Zhang, Zhi Nie, Chunyan Qing, Tingqi Lu, Qihua Pang, Wenzheng Pei, Hongmei Chen, Chenyan He, Bowen Luo, Dan He

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A Genome Scaffold Algorithm for Extending Repetitive and Nonrepetitive Contigs by Shuaibin Lian, Gang Zheng, Ke Gong, Xiaoli Zhang, Jiantao Guo

“…The next generation sequencing platform produces massive short reads data. …”
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Identification of multiomics and immune infiltration-associated biomarkers for early gastric cancer: a machine learning-based diagnostic model development study by Kewei Du, Wenfei Hu, Shan Gao, Jianxin Gan, Chongge You, Shangdi Zhang

“…Methods We employed serum proteomics combined with bioinformatics to identify genes differentially expressed in the serum of non-metastatic GC patients. Single-cell RNA sequencing (ScRNA-seq) and immune infiltration analysis were performed to evaluate the relationship between gene expression and immune cell function. …”
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Simulation-Based Hierarchical Heuristic for Printed Circuit Board Assembly Optimization in a Spin-Head Surface Mounter by Longlong Xu, Yarong Chen

“…This article proposes a simulation-based hierarchical heuristic (SHH) method to optimize nozzle assignment, feeder assignment, and component sequencing in a single spin-head gantry type surface mounter. …”
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Inherited glycosylphosphatidylinositol deficiency disorders: a new group of inherited metabolic disorders by Michał Patalan, Alicja Leśniak, Justyna Paprocka, Agnieszka Zubkiewicz-Kucharska, Kaja Giżewska-Kacprzak, Marta Glińska, Lidia Babiak-Choroszczak, Maria Giżewska, Robert Śmigiel

“…The current state of knowledge connects the highly differentiated course of clini­cal presentation with the heterogenic molecular background evaluated in the next-generation sequencing methods. …”
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CoPaD-Mark: A Coded Parallelizable Deep Learning-Based Scheme for Robust Image Watermarking by Andy M. Ramos, Cecilio Pimentel, Daniel P. B. Chaves

“…This code&#x2019;s message is constructed by combining a chaotic binary sequence with the original watermark bits. The inclusion of chaotic sequences adds randomness and complexity to the encoding process, enhancing robustness against attempts to alter the watermark. …”
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Wilson’s Disease Caused by Previously Undescribed Homozygous Nucleotide Variant of the <i>ATP7B</i> Gene: Clinical Cases by Denis K. Chernevskiy, Alla E. Lavrova, Ekaterina Yu. Konovalova, Elena Yu. Borisova, Natalia A. Doroshchuk, Olga S. Groznova

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Genetic insights into progressive myoclonic epilepsies: A case study of KCTD7 mutation in an Iranian-Azeri-Turkish family by Haneieh Honarmand, Mortaza Bonyadi, Mohammad Barzegar

“…A 5-year-old boy and his 8-year-old sister, presenting with PME-related electroclinical features such as myoclonic seizures and progressive cognitive and motor decline, underwent comprehensive clinical evaluations, including pedigree analysis, laboratory tests, and EEG assessments, followed by Whole-Exome Sequencing (WES) to identify potential disease-causing mutations. …”
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Respiratory transmission potential of severe fever with thrombocytopenia syndrome bunyavirus: evidence from intranasal exposure in a humanized mouse model by Dafeng Lu, Yifang Han, Ruowei Xu, Chunfang Wang, Mingke Qin, Jianwei Shi, Fuqiang Ye, Jinhai Zhang, Zhenghan Luo, Yuhe Wang, Hong Lin, Peiqi Jia, Jin Zhu, Chunhui Wang

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Identification of a novel AGO2 variant causing LESKRES in a Chinese family with intellectual disability by Shufa Yang, Wei Song, Yousheng Yan

“…BackgroundLessel-Kreienkamp syndrome (LESKRES, MIM #619149), an autosomal dominant genetic disorder caused by variants in AGO2 (MIM*606229), primarily leads to neurodevelopmental symptoms.ObjectiveThis study aims to investigate the genetic etiology of a family with intellectual disability.MethodsWhole-exome sequencing (WES) was used to initially identify the pathogenic variants responsible for the intellectual disability in the family, and Sanger sequencing was employed for confirmation. …”
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