Effect of exercise training on cardiac function and glucose metabolism in the ischemic border zone: insights from multi-modal imaging techniques by Jun Zhang, Jun Zhang, Jun Zhang, Chunrong Jin, Xiao Han, Xiao Han, Ping Wu, Ping Wu, Jianbo Cao, Jianbo Cao, Jianbo Cao, Sheng He, Sheng He, Li Li, Li Li, Ruonan Wang, Ruonan Wang, Min Zhang, Min Zhang, Yuxin Xiao, Yuxin Xiao, Hongju Guo, Tianshuo Zhang, Zhifang Wu, Zhifang Wu, Zhifang Wu, Sijin Li, Sijin Li, Sijin Li

“…Molecular and pathological analyses, including qPCR and Western blot, were conducted to evaluate mRNA and protein expression related to glucose metabolism. …”
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The role of vitamin D in sleep regulation: mechanisms, clinical advances, and future directions by Zhilong Cai, Shuoyu Rui, Nanqu Huang, Fei Feng, Yong Luo

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Effects of Somatic Mutations Are Associated with SNP in the Progression of Individual Acute Myeloid Leukemia Patient: The Two-Hit Theory Explains Inherited Predisposition to Pathog... by Soyoung Park, Youngil Koh, Sung-Soo Yoon

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Integrating datasets to dissect NFYC-AS1 RNA- and transcription-dependent functions: comparative transcriptome profiling of knockdown strategiesGene Expression Omnibus GEO by Giulia Pagani, Cecilia Pandini, Martina Tassinari, Paolo Gandellini

“…We describe in detail the strategies used to silence the asRNA and evaluate the consequences at the transcriptome level by RNA-sequencing. …”
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Daily intake of a dairy-based nutritional supplement improved self-reported gastrointestinal symptoms and modulated microbiota in adult Chinese volunteers by Klaudyna Borewicz, Yifan Zhao, Yaqiong Zhu

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Admixture and introgression obscure evolutionary patterns in lesser whitethroat complex (Curruca curruca; Passeriformes; Aves) by Raziyeh Abdilzadeh, Stefan Prost, Mansour Aliabadian, Arya Shafaeipour, Fumin Lei, Aleem Ahmed Khan, Urban Olsson

“…The results also show possible evidence of admixture from other populations in the LWT complex, extralimital to the sampled area, but the nature of this needs to be evaluated based on a larger data set.…”
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Spatial transcriptomics and scRNA-seq: decoding tumor complexity and constructing prognostic models in colorectal cancer by Wei Song, Yatao Wang, Min Zhou, Fengqin Guo, Yanliang Liu

“…Abstract Introduction Recent advancements in transcriptomic analysis, combined with single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics, have deepened our understanding of the tumor microenvironment and cellular heterogeneity, laying the groundwork for personalized therapies. …”
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Analysis of the Changes in Physicochemical Properties and Microbial Communities During Fermentation of Sweet Fermented Rice by Jiaqiong Wan, Ping Tian, Xiaozhen Liu, Hanyao Zhang

“…However, the physicochemical properties, microbial community composition, and metabolic pathway changes during the fermentation process of sweet wine have not been evaluated, and these changes can lead to unstable SFR quality. …”
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Case report: Inflammatory bowel disease in Hermansky-Pudlak syndrome type 3 due to novel variant in HPS3 by Jingqun Mai, Jingqun Mai, Zhu Zhang, Zhu Zhang, Bocheng Xu, Bocheng Xu, Shanling Liu, Shanling Liu, He Wang, He Wang, Hao Wang, Hao Wang, Shuo Yang, Shuo Yang

“…Colonoscopy and histopathological evaluations revealed extensive colonic inflammation characterized by erosion and lymphoid hyperplasia. …”
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Tape Strip Profiling of Checkpoint Inhibitor–Associated Dermatitis Highlights Pan-T-Cell Activation: A Pilot Study by Camille M. Powers, Madeline Kim, Annie Chang, Benjamin D. Hu, Brandon R. Block, Austin J. Piontkowski, Jeremy Orloff, Jade N. Young, Yeriel D. Estrada, Digpal S. Gour, Emma Guttman-Yassky, Nicholas Gulati

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Molecular Characterization, Antibiogram, and Virulence Gene Profiling of Proteus vulgaris Isolated From Cattle With Bovine Respiratory Disease in Bangladesh by Md. Abdur Rahman, Farah Zereen, Dipok Kumar Halder, Md. Al‐Amin, Md. Golzar Hossain, Masaru Shimada, Sukumar Saha

“…Identification was performed through Gram staining, biochemical assays and molecular techniques, including PCR and partial gene sequencing. Antibiotic susceptibility was evaluated using the disc diffusion method, and virulence genes were detected by PCR. …”
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Immune checkpoint inhibitor‐related molecular markers predict prognosis in extrahepatic cholangiocarcinoma by Bao Jin, Yuxin Wang, Baoluhe Zhang, Haifeng Xu, Xin Lu, Xinting Sang, Wenze Wang, Yilei Mao, Pengxiao Chen, Shun Wang, Zhirong Qian, Yingyi Wang, Shunda Du

“…Methods Whole‐exome sequencing (WES) on 37 tissue samples of EHCC were performed to evaluate genomic alterations, tumor mutational burden (TMB) and microsatellite instability (MSI). …”
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Metagenomic Profiling of Oral Microbiome Dynamics During Chemoradiotherapy in Head and Neck Squamous Cell Carcinoma Patients by Dominique A. Torozan, Cédric Christian Laczny, Kirsten Roomp, Paul Wilmes, Jochen Fleckenstein, Jochen G. Schneider

“…Saliva samples were characterized prior to, during, and nine months after CRT using metagenomic sequencing. We similarly characterized samples from seven healthy controls. …”
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Influences of gestational diabetes mellitus on the changes in the vaginal microbiota from antepartum to postpartum by Ying Liao, Ting Liu, Xinfang Zeng, Bin Xiao, Meiqun Xiao, Yuanfang Zhu, Qiying Song

“…Vaginal microbiota was detected using 16S rRNA gene sequencing. Results There was no significant difference in alpha and beta diversity between the GDM and non-GDM groups at each time point (all p > 0.05). …”
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Ecological prevalence and genomic characterization of Salmonella isolated from selected poultry farms in Jiangxi province, China by Xiaowu Jiang, Abubakar Siddique, Lexin Zhu, Lin Teng, Sajid Umar, Yan Li, Min Yue

“…Raw chicken is the leading cause of human salmonellosis. In this study, we evaluated the prevalence, antimicrobial resistance profiles, and genomic features of 143/1,800 (7.94%) Salmonella strains isolated from poultry farms in five major regions of Jiangxi province, China, between 2022 and 2023 using Whole genome sequencing (WGS). …”
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Phenotypic and genotypic characterization of Mycobacterium tuberculosis pyrazinamide resistance—India, 2018–2020 by Sembulingam Tamilzhalagan, Evanslin Santus Justin, Ashok Selvaraj, Karthick Venkateswaran, Arun Kumar Sivakumar, Suganthi Chittibabu, Heather P. McLaughlin, Patrick K. Moonan, Jonathan P. Smith, Sakthi Suba, Mukesh Kumar Sathya Narayanan, Christine S. Ho, Nishant Kumar, Srikanth P. Tripathy, Srikanth P. Tripathy, Siva K. Shanmugam, Patricia J. Hall-Eidson, Uma Devi Ranganathan

“…This nationwide study was conducted to explore the prevalence of mutations conferring PZA resistance, catalogue mutation diversity, investigate the associations of PZA resistance with specific lineages, examine co-resistance to 13 first- and second-line drugs, and evaluate the diagnostic accuracy of sequencing pncA and panD genes for predicting PZA resistance. …”
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Seasonal dynamics and risk assessment of antibiotic resistome in straw-retained agroecosystems by Yi Wu, Yi Fan, Yiheng Tao, Quankuan Guo, Shuang Pang, Wei Yang, Ximei Zhang

“…Here, we conducted a multi-site field study in the Sanjiang Plain, a seasonally frozen agricultural region of Northeast China, combining time-series soil sampling with metagenomic sequencing to reveal antibiotic resistome dynamics. …”
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Somatic NLRP3 mosaicism in patients with “mutation-negative” CAPS: insights from a single centre UK cohort by Sonia Melo Gomes, Juan I. Arostegui, Ana Mensa-Vilaro, Ebun Omoyinmi, Ebun Omoyinmi, Ying Hong, Dara McCreary, Dorota Rowczenio, Philip Hawkins, Paul Brogan, Paul Brogan

“…IntroductionKnowledge about mosaicism in cryopyrin-associated periodic syndromes (CAPS) has expanded significantly with the use of next generation sequencing technologies. The aim of this study was to assess the contribution of mosaicism in a paediatric cohort of patients with a clinical diagnosis of CAPS and no NLRP3 mutations identified through conventional DNA sequencing.MethodsMosaicism was assessed by amplicon-based deep sequencing (ADS) on DNA extracted from different tissues overtime. …”
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Influence of Autochthonous Lactic Acid Bacteria Cultures on the Microbiota and Biogenic Amine Production in Medium-Ripened Artisan Goat Cheese by Julia Mariano Caju de Oliveira, Adriane Elisabete Costa Antunes, Gustavo Felipe Correia Sales, Camila Neves Meireles Costa, Angela Matilde da Silva Alves, Kaíque Yago Gervazio de Lima, Celso José Bruno de Oliveira, Antônio Silvio do Egito, Karina Maria Olbrich dos Santos, Evandro Leite de Souza, Maria Teresa Bertoldo Pacheco, Maria Elieidy Gomes de Oliveira

“…This study evaluated the effects of adding the autochthonous cultures <i>Limosilactobacillus mucosae</i> CNPC007 (LM) and <i>Lactiplantibacillus plantarum</i> CNPC003 (LP), originally isolated from goat milk and goat cheese, respectively, on microbiological safety, microbiota composition (analyzed through 16S rRNA gene metataxonomic sequencing), and biogenic amine (BA) production in artisanal goat (<i>coalho</i>) cheese made from raw or pasteurized milk during 60 days of ripening at 10 °C. …”
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Multidimensional bioinformatics analysis of chondrosarcoma subtypes and TGF-β signaling networks using big data approaches by Shengke Li, Junteng Chen, Fuping He, Maosheng Wang, Jun Liu, Hui Xie

“…Pseudotime analysis charted differentiation trajectories, while machine learning models evaluated the classification accuracy of gene expression patterns. …”
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