STABILITY (Symptomatic Review during Biologic Therapy) of Inflammatory Bowel Disease Patients Receiving Infusion Therapy Improves Clinical Outcomes by Kelli Morgan, James Morris, Qiang Cai, Phillip Kilgore, Urska Cvek, Marjan Trutschl, Katelynn T. Lofton, Meher Sindhoora Mavuram, Prerana Ramesh, Nhi Dao, Ahmed Alhaque, Jonathan Steven Alexander

“…To further investigate the impact of STABILITY, we conducted a comparative analysis between IBD patients undergoing STABILITY infusion therapy and LSUHS patients solely on self-injectable biologics. Our paired data analysis showed significant improvements in disease severity in female IBD patients (1.69 ± 0.13 vs. 1.41 ± 0.12, <i>p</i> = 0.0001) and male IBD patients (1.58 ± 0.16 vs. 1.2 ± 0.135, <i>p</i> = 0.004), in UC patients (1.833 ± 0.4.2 vs. 1.444, <i>p</i> = 0.043), in all CD patients (1.59 ± 0.11 vs. 1.29 ± 0.01, <i>p</i> = 0.0001), in male CD patients (1.52 ± 0.167 vs. 1.15 ± 0.15, <i>p</i> = 0.016), in female CD patients (1.66 ± 0.15 vs. 1.4 ± 0.13, <i>p</i> = 0.0003), in female UC patients (1.82 ± 0.32 vs. 1.45 ± 0.31, <i>p</i> = 0.0379), and marginally in male UC patients (<i>p</i> = 0.0781). …”
Get full text

Spatial Distribution of Domestic Violence in Kermanshah City by zhila ghazvineh, bagher saroukhani, Alieh shekarbigi

“…High levels of unemployment and low income, migration and the spread of marginalization, which are widespread in urban poor areas, have had a direct impact on violence. …”
Get full text

Plasma-wall interaction impact of the ITER re-baseline by R.A. Pitts, A. Loarte, T. Wauters, M. Dubrov, Y. Gribov, F. Köchl, A. Pshenov, Y. Zhang, J. Artola, X. Bonnin, L. Chen, M. Lehnen, K. Schmid, R. Ding, H. Frerichs, R. Futtersack, X. Gong, G. Hagelaar, E. Hodille, J. Hobirk, S. Krat, D. Matveev, K. Paschalidis, J. Qian, S. Ratynskaia, T. Rizzi, V. Rozhansky, P. Tamain, P. Tolias, L. Zhang, W. Zhang

“…Boundary plasma (SOLPS-ITER) and integrated core–edge (JINTRAC) simulations, including W erosion and transport, clearly indicate the tendency for a self-regulating W sputter source in limiter configurations and highlight the importance of on-axis electron cyclotron power deposition to prevent W core accumulation in the early current ramp phase. …”
Get full text

The Strategy of Young Citizens in the Field of Unanswered Demands: A Qualitative Study in Yazd City by Fezzeh Abolhasani, Mahnaz Farahmand, Hossein Afrasiabi, Seyed Reza Javadian

“…Understanding these strategies is crucial for developing responsive and inclusive policies that can address the evolving needs and concerns of the citizenry.The citizens' statements pointed to a complex societal landscape marked by poverty, marginalization, unequal access to resources, dominance of ideology over public space, marginalization of certain groups, and inefficiency and misconduct of institutions. …”
Get full text

Altered brain network dynamics during rumination in remitted depression by Su Shu, Wenwen Ou, Mohan Ma, Hairuo He, Qianqian Zhang, Mei Huang, Wentao Chen, Aoqian Deng, Kangning Li, Zhenman Xi, Fanyu Meng, Hui Liang, Sirui Gao, Yilin Peng, Mei Liao, Li Zhang, Mi Wang, Jin Liu, Bangshan Liu, Yumeng Ju, Yan Zhang

“…Additionally, the findings suggest that heightened self-focus linked to rumination may impair the brain's ability to efficiently allocate attentional resources.…”
Get full text

Spatial Analysis of the Concentration of Knowledge-Based Firms in Iran by Najmoddin Yazdi, Mahdi Fateh-rad, Jamal Kadkhodapour, Siamak Tahmasbi

“…The results indicated that the distribution of knowledge-based firms was predominantly concentrated in metropolitan areas with no significant clusters forming in marginal regions, which had not reaped the associated benefits. …”
Get full text

Evaluation of parenting interventions for those with additional health and social care needs during pregnancy: THRIVE a multi-arm RCT with embedded economic and process components by Marion Henderson, Anja Wittkowski, Katie Buston, Karen Crawford, Alice MacLachlan, Alex McConnachie, Emma McIntosh, Claudia-Martina Messow, Catherine Nixon, Rosaleen O’Brien, Shona Shinwell, Daniel Wight, Yiqiao Xin, Rachel Calam, Ruth Dundas, James Law, Helen Minnis, Lucy Thompson, Philip Wilson

“…Results From the 964 referrals received, 488 participants were recruited to THRIVE (marginally below the aspired 500) and completed baseline assessments. …”
Get full text

INTERBLOCK ZONES IN THE CRUST OF THE SOUTHERN REGIONS OF EAST SIBERIA: TECTONOPHYSICAL INTERPRETATION OF GEOLOGICAL AND GEOPHYSICAL DATA by K. Zh. Seminsky, N. O. Kozhevnikov, A. V. Cheremnykh, E. V. Pospeeva, A. A. Bobrov, V. V. Olenchenko, M. A. Tugarina, V. V. Potapov, R. M. Zaripov, A.S. Cheremnykh

“…We used structural geological methods for studying faults and fractures, morphostructural analysis (including interpretation of satellite images), self-potential (SP) and resistivity profiling, magnetotelluric (MT) sounding, radon emanation survey, and hydrogeological studies of water occurrences. …”
Get full text

Clinical and cost-effectiveness of paramedics working in general practice: a mixed-methods realist evaluation by Matthew Booker, Sarah Voss, Nicky Harris, William Hollingworth, Nouf Jeynes, Hazel Taylor, Kirsty Garfield, Helen Baxter, Jonathan Benger, Andy Gibson, Trudy Goodenough, Justin Jagosh, Kim Kirby, Cathy Liddiard, Alyesha Proctor, Sarah Purdy, Behnaz Schofield, Hannah Stott, Grace Scrimgeour, Nicola Walsh

“…The case study design included sites that were by definition self-selecting, which may have decided to take part due to a desire to demonstrate the perceived effectiveness of PGP. …”
Get full text

Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…There were 64 intervention participants and 79 controls at 6 months but on combinations of societal costs and self-completed HRQoL measures, only 25 cases were available for analysis. …”
Get full text

Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT by Graham Devereux, Seonaidh Cotton, Mintu Nath, Nicola McMeekin, Karen Campbell, Rekha Chaudhuri, Gourab Choudhury, Anthony De Soyza, Shona Fielding, Simon Gompertz, John Haughney, Amanda Lee, Graeme MacLennan, Alyn Morice, John Norrie, David Price, Philip Short, Jorgen Vestbo, Paul Walker, Jadwiga Wedzicha, Andrew Wilson, Olivia Wu, Brian Lipworth

“…These findings indicate that including bisoprolol alongside usual care for people with COPD is marginally more costly and less effective than placebo; bisoprolol intervention would be termed as ‘dominated’. …”
Get full text