Polycomplex Carrier for Buccal Mucoadhesion Delivery of Metronidazole by R. I. Moustafine, V. V. Budnikov, S. G. Abdullina, Sh. F. Nasibullin, R. A. Saleev

“…As a result of studies on the physicochemical and pharmaceutical properties, there was selected the optimal composition of a polycomplex carrier (IPEC 2) based on Eudragit® EPO and Noveon® AA-1, which is characterized by the required bioadhesive properties and the ability of providing controlled release of drug from the tablet matrix (with weight ratio MD/IPEC-2 1:0.5) in conditions mimicking oral cavity environment, which provides the necessary mode of buccal delivery of metronidazole in accordance with Fick's law of diffusion.Conclusion. …”
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Thin GB14 coatings on implants using HVSFS by Maria Carolina Lanzino, Long-Quan R. V. Le, Janka Wilbig, Wolfgang Rheinheimer, Michael Seidenstuecker, Jens Günster, Andreas Killinger

“…Increasing stand-off distance while reducing gas stoichiometry enabled the production of calcium alkali orthophosphate coatings with fewer cracks, higher porosity and a hardness level comparable to that of state-of-the-art tricalcium phosphate (TCP) coatings. The sample with optimized properties in terms of achieved microstructure and topography was selected for in vitro testing using MG63 osteosarcoma cells to evaluate cell proliferation and adhesion. …”
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Biochar Quality During Slow Pyrolysis from Oil Palm Empty Fruit Bunches and Its Application as Soil Ameliorant by Amsar Maulana, Mimien Harianti, Salma Athiyya, Teguh Budi Prasetyo, Moli Monikasari, Irwan Darfis, Dewi Rezki, Herviyanti Herviyanti

“…The optimal utilization of oil palm empty fruit bunch (OPEFB) waste holds significant potential for biomass bioconversion via slow pyrolysis, presenting a promising alternative for producing high-quality biochar as a soil ameliorant. …”
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Greenness assessment profile of experimentally designed chromatographic method for the simultaneous analysis of ofloxacin and racecadotril in the presence of racecadotril impuritie... by Nada Nabil, Ghada A. Sedik, Hala E. Zaazaa, Sally S. El-Mosallamy

“…Experimental design using face-centred composite design was utilized during method optimization to obtain the highest level of resolution with the fewest number of experimental trials for the determination of ofloxacin (OFLU) and racecadotril (RAC) in the presence of RAC impurities. …”
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Comparative Analysis of Generative Artificial Intelligence Systems in Solving Clinical Pharmacy Problems: Mixed Methods Study by Lulu Li, Pengqiang Du, Xiaojing Huang, Hongwei Zhao, Ming Ni, Meng Yan, Aifeng Wang

“…MethodsForty-eight clinically validated questions were selected via stratified sampling from real-world sources (eg, hospital consultations, clinical case banks, and national pharmacist training databases). …”
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Fabrication of PSf/P84-blended membranes with low P84 content: Characteristics and gas separation performance by Victor Kayadoe, Nurul Widiastuti, Triyanda Gunawan, Wan Norhayati Wan Salleh, Hamzah Fansuri, Taufik Qodar Romadiansyah, Agus Wedi Pratama

“…The highest N2/CH4 selectivity (6.29, 253 % increase) was observed with the 1:0.10 composition. …”
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Characteristics and risk profile of the over fifty adult congenital heart surgical population, a retrospective cohort by Matthanja Bieze, Oliver Poole, Arshia Delfani, Jane Heggie, Jane Heggie, Marcus Salvatori

“…No difference was seen in 1-year mortality (P = 0.415).ConclusionWith careful patient selection and preoperative optimization, surgical risks remain low, even in aging ACHD patients. …”
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Approach to automating viral genome assembly by Ms Anastasiia Paremskaia, Dr Andrei Deviatkin, Dr Pavel Volchkov

“…However, the remaining portion of this segment shows no homology. In this case, the optimal solution would be to select the most suitable reference from a representative database. …”
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Quantitative determination of the components of the mixture – ear drops “Melavet” by the method of high-performance liquid chromatography by V. V. Parchenko, D. Datsiuk, V. Hunchak, V. Martynyshyn

“…During the research, a highly sensitive technique for the simultaneous determination of the components of the model mixture “Melavet” ear drops 10 ml by the method of high-performance liquid chromatography was developed. The optimal conditions for the simultaneous determination of the components of the mixture in one sample are selected. …”
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How spatial resolution mediates canopy spectral diversity as a proxy for marsh plant diversity by Yi Fu, Yunlong Yao, Lei Wang, Huaihu Yi, Yuanqi Shan

“…Spectral reflectance variations comprehensively capture differences in the biochemical composition and morphological characteristics among plant species, making them a promising approach for monitoring and estimating plant diversity. …”
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Machine learning in additive manufacturing——NiTi alloy’s transformation behavior by Lidong Gu, Kongyuan Yang, Hongchang Ding, Zezhou Xu, Chunling Mao, Panpan Li, Zhenglei Yu, Yunting Guo, Luquan Ren

“…To investigate the accuracy of the model, this study utilized various process parameters to fabricate NiTi alloys with different compositions from Ni50.8Ti49.2 alloy powder. Using this model, the study identified a novel, larger window of optimal LPBF processing that allows for controllable complex phase transitions.…”
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Harnessing loblolly pine (Pinus taeda L.) for sustainable biofuels and bioenergy: A review of biomass feedstock potential, conversion technologies, and forest management in the US by Chioma Edwina Ogbuka, Pradip Saud, Marco Yáñez, Rajan Parajuli, Sagar Godar Chhetri, Matthew Pelkki

“…However, gaps remain, particularly in integrating technological and silvicultural optimizations. This study reviewed the existing literature on the potential of loblolly pine as a sustainable alternative feedstock for bioenergy production, including conversion technologies, cellular composition, derivative products, genetic improvement, and forest management practices. …”
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Biological and physical fitness adaptations in soccer players after jump training: a systematic scoping review by Rohit Kumar Thapa, Exal Garcia-Carrillo, Andrew Sortwell, Paul J. Byrne, José Afonso, Rodrigo Ramirez-Campillo

“…Methods Included studies incorporated: (i) soccer players; (ii) jump-training interventions; and (iii) outcomes related to physical fitness (e.g. endurance). Selection was not based on comparator groups and/or study designs. …”
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Research on fault monitoring of belt conveyor based on FBG sensor by Xinqiu FANG, Yang WU, Yang SONG, Ningning CHEN, Yulong FENG, Haotian FENG, Dexing HE, Fukang QIAO

“…The influencing factors on sensitivity and accuracy are analyzed within the sensing model, guiding the determination of the structural dimensions of the sensing elements. Nylon 6 is selected as the optimal material for fabrication.Finally, experimental validation is performed to assess the structural effectiveness, sensitivity, and stability of the FBG-based equal-strength cantilever beams. …”
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Genetic Evaluation of Early Growth Traits in Yunnan Semi-Fine Wool Sheep by Yaqian Wang, Hongyuan Yang, Xiaoqi Zhao, Xiaojun Ni, Yuanchong Zhao, Zhengrong You, Qingwei Lu, Sen Tang, Guobo Quan, Xuefeng Fu

“…This study not only identified the optimal animal models for early growth traits in Yunnan semi-fine wool sheep, offering a precise basis for estimating genetic parameters but also provides theoretical guidance for genetic selection and breed improvement in this population.…”
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Hybrid Soybean as Green Manure for Improving Soil Properties and Subsequent Crop Growth by Haibo Qi, Bangrui Li, Junmei Fan, Wei Zhao, Yiming Ma, Yuan Suo, Mingjiu Wang, Yong Wang

“…The diversity and richness of soil bacterial communities increased significantly, accompanied by alterations in community structure and composition. These changes enhanced soil fertility and optimized the microbial community structure, promoting the growth of subsequent crops. …”
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Effесt of Chеmiсаl Cоmposition оn thе Miсrоstruсture, Hаrdnеss, аnd Elесtrical Conductivity Profiles of the Bi-Gе-X (Gа, Cu, Zn) Allоys by A. Djordjević, M. Zečević, D. Minić, M. Kolarević, D. Manasijević, V. Ristić

“…In all three investigated ternary systems an isothermal section at 25°C was selected for experimental testing. Based on the optimized thermodynamic parameters for the constitutive binary systems, the calculation was performed. …”
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Rhizosphere-associated bacterial and fungal communities of two maize hybrids under increased nitrogen fertilization by Qing Liu, HongCui Dai, Hao Cheng, Guodong Shao, Liang Wang, Hui Zhang, Yingbo Gao, Kaichang Liu, Xiaomei Xie, Junhua Gong, Xin Qian, Zongxin Li

“…Our findings illustrate the relationship between the appropriate selection of crop hybrids and management measures in optimizing rhizosphere microbial community assembly and promoting nitrogen use, which is necessary for sustainable food security.…”
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Effects of dietary faba bean (Vicia faba L.) inclusion on carcass characteristics, meat quality, and blood biochemistry in Awassi lambs by Belal S. Obeidat, Nawras L. Al Shabuol, Linda Alyahya

“…Conclusion: The inclusion of 20% FB in the diet of Awassi lambs improved carcass composition and meat quality without negatively affecting animal health. …”
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Standardization of the Pharmaceutical Substance of Lithium Salt Gamma-lactone of 2,3-dehydro-l-gulonic Acid as a Radio-sensitizing Agent by M. S. Tretyakova, S. V. Krivoshchekov, E. V. Plotnikov, E. V. Dorozhko, O. A. Voronova, M. S. Larkina, K. S. Brazovskiy, M. V. Belousov

“…A draft specification for the pharmaceutical substance of the lithium salt gamma-lactone 2,3-dehydro-L-gulonic acid has been developed. The optimal parameters for the control of the composition and physico-chemical characteristics and quantitative determination of the pharmaceutical substance have been determined, which is the main task for the pharmaceutical development of the drug. …”
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