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701
Machine learning discovery of the dielectric properties of strontium-containing condensed matter
Published 2025-06-01“…In this work, machine learning models were successfully developed to capture the relationship between composition and dielectric properties of strontium-containing dielectrics using different algorithms, with hyperparameter optimization performed via grid search. …”
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702
Predictive Analysis of Mechanical Properties in Cu-Ti Alloys: A Comprehensive Machine Learning Approach
Published 2024-07-01“…A machine learning-based approach is presented for predicting the mechanical properties of Cu-Ti alloys utilizing a dataset of various features, including compositional elements and processing parameters. The features encompass chemical composition elements such as Cu, Al, Ce, Cr, Fe, Mg, Ti, and Zr, as well as various thermo-mechanical processing parameters. …”
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703
Recovery of Volatile Fatty Acids from Fermentation Broth Using Ethyl Acetate as Solvent
Published 2025-07-01“…Experimental conditions were optimized by varying the pH (2.5–4.5) and stirring time (10–60 minutes). …”
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704
Non-traditional plant raw materials in the production technology of flour confec-tionery products
Published 2024-10-01“…This requires careful selection of ingredients and optimization of technological processes to ensure stability and high quality of products.…”
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705
Host-specific effects of Eubacterium species on Rg3-mediated modulation of osteosarcopenia in a genetically diverse mouse population
Published 2024-12-01“…Results Rg3 treatment altered gut microbiota composition aligned with osteosarcopenia phenotypes, which response varied depending on host genetics. …”
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706
Exploring non-invasive biomarkers for pulmonary nodule detection based on salivary microbiomics and machine learning algorithms
Published 2025-03-01“…Furthermore, the Bayesian optimization algorithm was used to optimize this best-performing model. …”
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707
Impacts of coffee parchment on growth, immunity, and gut microbiota of Nile tilapia (Oreochromis niloticus) in biofloc system
Published 2025-07-01“…Microbiota analysis revealed 69 shared ASVs across treatments, with CP supplementation causing clear shifts in bacterial composition. CP5 reduced Proteobacteria abundance and microbial richness and evenness, suggesting selective modulation of gut communities. …”
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708
Gas Chromatography-Mass Spectrometry of Volatile Organic Impurities in Whiskey
Published 2022-12-01“…The research revealed the optimal parameters of chromatographic separation and mass spectrometric detection. …”
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709
The use of machine learning methods in the development of nasal dosage forms with cerebroprotective action
Published 2021-07-01“…The use of machine learning models in pharmaceutical development will contribute to resource conservation and optimization of the composition of the formulation.…”
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710
Intelligent prediction and oriented design of high-hardness high-entropy ceramics
Published 2025-05-01“…This achievement is attributed to three key innovations: the construction of the feature space based on the Pearson correlation coefficient and genetic algorithm, along with algorithm selection and optimization through hyperparameter tuning; the novel combination of reduced-dimensionality component compositions with atomic/precursor descriptors, achieving a model R2 value of up to 0.898; the optimization of constituent elements using genetic algorithm and principal component analysis, providing direct guidance for the design of high-hardness high-entropy ceramics. …”
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711
Marine actinomycetes: A promising source of novel therapeutics and pharmaceutical bioactive compounds – A review
Published 2025-06-01“…Pretreatment techniques, selective media, and antibiotics in enrichment culture effectively isolate new actinomycetes that produce various secondary metabolites. …”
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712
The impact of the nucleosome code on protein-coding sequence evolution in yeast.
Published 2008-11-01“…Coding sequence evolution was once thought to be the result of selection on optimal protein function alone. Selection can, however, also act at the RNA level, for example, to facilitate rapid translation or ensure correct splicing. …”
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713
Synergistic Pd-La Catalysts on ATO for Clean Conversion of Methane into Methanol and Electricity
Published 2025-01-01“…Polarization curves and power density plots highlighted the Pd<sub>50</sub>La<sub>50</sub>/ATO catalyst, indicating an optimal palladium/lanthanum ratio for methanol optimization. …”
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714
Flowsheets for hydroxyacetone–phenol binary mixture separation: The use of special distillation methods
Published 2023-11-01“…The dependence of the composition and boiling point of the hydroxyacetone–phenol azeotrope on pressure was determined in a computational experiment (as the pressure increases, the azeotrope is enriched with phenol). …”
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715
Application of in-silico docking for green electrochemical quantification of prucalopride succinate in pharmaceutical, urine, and milk matrices
Published 2025-02-01“…So, three distinct polyvinyl chloride sensors modulated by ionophores of cyclodextrins (α-, β-, and γ-cyclodextrins) were built, and their composition was optimized for rapid in-situ estimation of prucalopride succinate in different matrices. …”
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716
P71 | THE EXTRACELLULAR VESICLE POPULATIONS UNDERWENT ALTERATIONS SUBSEQUENT TO THE PRETREATMENT OF ADIPOSE-DERIVED STEM CELLS WITH MELATONIN RECEPTOR AGONIST
Published 2025-08-01“…In this context, the use of tasimelteon, a selective melatonin receptor agonist, offers a novel approach to modulating melatonin receptor mediated pathways in ADSCs. …”
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717
Effect of the 16S rRNA Gene Hypervariable Region on the Microbiome Taxonomic Profile and Diversity in the Endangered Fish <i>Totoaba macdonaldi</i>
Published 2024-10-01“…However, this approach faces challenges including the co-amplification of host mitochondrial sequences and the variability in bacterial composition influenced by the selected 16S rRNA gene regions. …”
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718
A Comprehensive Review and Analysis of the Design Aspects, Structure, and Applications of Flexible Wearable Antennas
Published 2025-01-01“…Additionally, solutions for SAR optimization, including the use of metamaterials, electromagnetic band gap (EBG) structures, and frequency-selective surfaces (FSSs), are discussed. …”
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719
Review of machine learning-assisted multi-property design of high-entropy alloys: phase structure, mechanical, tribological, corrosion, and hydrogen storage properties
Published 2025-07-01“…It outlines the basic workflow, including data collection, data preprocessing, ML algorithm selection, hyperparameter optimization, model evaluation and model interpretability. …”
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720
Key considerations based on pharmacokinetic/pharmacodynamic in the design of antibody-drug conjugates
Published 2025-01-01“…Through the selection of target antigen, the optimization of the linker, the optimization of novel small molecule toxins as payload, the optimization of ADC, overcoming the multi-drug resistance of ADC, improving the ADC tumor penetration of ADC, surface modification of ADC and surface bystander effect of ADC provide a more comprehensive and accurate framework for designing new ADCs.ResultsWe’ve expounded comprehensively on applying pharmacokinetics or pharmacodynamics while designing ADC to obtain higher efficacy and fewer side effects. …”
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