Supersaturated Gel Formulation (SGF) of Atorvastatin at a Maximum Dose of 80 mg with Enhanced Solubility, Dissolution, and Physical Stability by Jin Woo Park, Sa-Won Lee, Jun Hak Lee, Sung Mo Park, Sung Jun Cho, Han-Joo Maeng, Kwan Hyung Cho

“…PEG 200 demonstrated very high solubility for ATR (>60%, <i>w</i>/<i>w</i>), and the combined use of TPGS and PEG 200 formed an organogel state and suppressed ATR precipitation, showing 15-fold higher dispersion solubility in buffer solution at pH 1.2 compared to the formulation with PEG 200 alone. The optimal SGF composition (ATR/PEG 200/TPGS = 10/60/30, <i>w</i>/<i>w</i>) exhibited an over 95% dissolution rate within 2 h at pH 1.2, compared to less than 50% for the original commercial product. …”
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Influence of the nature of organic solvents on the process of separation of antioxidative additive in a transformer oil by a gas-chromatographic method by Duy Hung Nguyen, Yu. V. Snigireva, A. V. Taneeva, V. F. Novikov

“…In this case, the most optimal separation selectivity, approaching one, is characteristic of the Ionol – Butanol-1 pair. …”
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Liquefied dimethyl ether as alternative extraction solvent for high γ-oryzanol rice bran oil: Systematic HSP theory and experimental evaluation by Phannipha Daisuk, Seiichi Takami, Masaki Honda, Motonobu Goto, Chonlatep Usaku, Artiwan Shotipruk

“…Oils extracted with LDME and hexane displayed similar fatty acid compositions and no adverse effects on RB protein and carbohydrate structures after LDME extraction were observed. …”
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Effect of Acoustic Pressure on Temozolomide-Loaded Oleic Acid-Based Liposomes and Its Safety to Brain Tissue by Vasilisa D. Dalinina, Vera S. Shashkovskaya, Iman M. Khaskhanova, Daria Yu. Travnikova, Nelly S. Chmelyuk, Dmitry A. Korzhenevskiy, Vsevolod V. Belousov, Tatiana O. Abakumova

“…In this study, we developed liposomal formulations with optimized temozolomide (TMZ)’s loading and analyze its response to focused ultrasound (FUS). …”
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New Insights into Common Bean (<i>Phaseolus vulgaris</i> L.) Sprouts: Pilot Studies on the Formulation of a Cosmeceutical Based on Micellar Extracts Bean Sprouts by Katarzyna Wojciechowska, Ewelina Rostkowska, Grażyna Ginalska, Łukasz Zimmer, Ewa Poleszak

“…For the in vivo efficacy tests, the cream, which exhibited optimal physicochemical properties and long-term stability, was selected and tested on a group of 45 volunteers. …”
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Synthesis of Acrylic Acid Polymer Hydrogel Nano Fe3O4 to Remove Ammonia from Sugarcane Field Waste by Amirhosein Fazilati, Nader Mokhtarian, Ali Mohammad Latifi, Mohammad Fazilati

“…The inflation rate of these hydrogels was selected to be 991.52 (mg/g) under optimal conditions, and the nanomagnetic hydrogel adsorption capacity remained constant at a pH range of 4 to 9, while when the pH was below four or above 9, the capacity of adsorption shows a slight decrease. …”
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Preparation of all solid-state electrolyte lithium ion batteries by multi-layer co-fired process by Shieh Derrick, Wang Sea-Fue, Chi Po-Wei, Hsu Yung-Fu, Wu Kuen Maw

“…Future work will be focused on optimizing the cell by adjusting experimental parameters for enhanced performance.…”
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Preliminary Qualitative Analysis of Plant Samples by High-performance Thin-layer Chromatography for the Presence of Steroid Sapogenins of Some Representatives of the Dioscoreacae,... by A. E. Sukhanov, I. A. Krylov, V. V. Sepp, K. S. Bakulin

“…This work is exploratory in nature, assessing the presence of certain saponins by their sapogenins in selected extracts. We will optimize the HPLC separation procedure and choose other detection methods to unambiguously assess the co-presence of the studied sapogenins with approximately the same staining shades after derivatization and matching retention indices: there are pairs of steroidal sapogenins that have the same retention, we decided to group them in mixtures so that there would be separation within the group and subsequent comparison with the original extracts would make it possible to identify those or other sapogenins in such extracts.…”
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Polycomplex Carrier for Buccal Mucoadhesion Delivery of Metronidazole by R. I. Moustafine, V. V. Budnikov, S. G. Abdullina, Sh. F. Nasibullin, R. A. Saleev

“…As a result of studies on the physicochemical and pharmaceutical properties, there was selected the optimal composition of a polycomplex carrier (IPEC 2) based on Eudragit® EPO and Noveon® AA-1, which is characterized by the required bioadhesive properties and the ability of providing controlled release of drug from the tablet matrix (with weight ratio MD/IPEC-2 1:0.5) in conditions mimicking oral cavity environment, which provides the necessary mode of buccal delivery of metronidazole in accordance with Fick's law of diffusion.Conclusion. …”
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Thin GB14 coatings on implants using HVSFS by Maria Carolina Lanzino, Long-Quan R. V. Le, Janka Wilbig, Wolfgang Rheinheimer, Michael Seidenstuecker, Jens Günster, Andreas Killinger

“…Increasing stand-off distance while reducing gas stoichiometry enabled the production of calcium alkali orthophosphate coatings with fewer cracks, higher porosity and a hardness level comparable to that of state-of-the-art tricalcium phosphate (TCP) coatings. The sample with optimized properties in terms of achieved microstructure and topography was selected for in vitro testing using MG63 osteosarcoma cells to evaluate cell proliferation and adhesion. …”
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Biochar Quality During Slow Pyrolysis from Oil Palm Empty Fruit Bunches and Its Application as Soil Ameliorant by Amsar Maulana, Mimien Harianti, Salma Athiyya, Teguh Budi Prasetyo, Moli Monikasari, Irwan Darfis, Dewi Rezki, Herviyanti Herviyanti

“…The optimal utilization of oil palm empty fruit bunch (OPEFB) waste holds significant potential for biomass bioconversion via slow pyrolysis, presenting a promising alternative for producing high-quality biochar as a soil ameliorant. …”
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In vitro machine learning-based CAR T immunological synapse quality measurements correlate with patient clinical outcomes. by Alireza Naghizadeh, Wei-Chung Tsao, Jong Hyun Cho, Hongye Xu, Mohab Mohamed, Dali Li, Wei Xiong, Dimitri Metaxas, Carlos A Ramos, Dongfang Liu

“…To improve their efficacy and expand their applicability to solid tumors, scientists optimize different CARs with different modifications. …”
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Toxicity comparison of two nanocarriers, magnetic mesoporous silica and polyoxometalate, using in vitro methods in PC-3 cells by Elaheh Valizadehkakhki, Farrokhzad Mohammadi Zonoz, Amir Shokouh Saljooghi, Maryam Moghaddam Matin, Zahra Sadat Ahmadi Koopaee

“…SPION@silica, with its favorable safety profile, emerges as a promising candidate for targeted drug delivery, though its lower tumor suppression efficacy warrants further optimization.…”
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Greenness assessment profile of experimentally designed chromatographic method for the simultaneous analysis of ofloxacin and racecadotril in the presence of racecadotril impuritie... by Nada Nabil, Ghada A. Sedik, Hala E. Zaazaa, Sally S. El-Mosallamy

“…Experimental design using face-centred composite design was utilized during method optimization to obtain the highest level of resolution with the fewest number of experimental trials for the determination of ofloxacin (OFLU) and racecadotril (RAC) in the presence of RAC impurities. …”
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Comparative Analysis of Generative Artificial Intelligence Systems in Solving Clinical Pharmacy Problems: Mixed Methods Study by Lulu Li, Pengqiang Du, Xiaojing Huang, Hongwei Zhao, Ming Ni, Meng Yan, Aifeng Wang

“…MethodsForty-eight clinically validated questions were selected via stratified sampling from real-world sources (eg, hospital consultations, clinical case banks, and national pharmacist training databases). …”
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Fabrication of PSf/P84-blended membranes with low P84 content: Characteristics and gas separation performance by Victor Kayadoe, Nurul Widiastuti, Triyanda Gunawan, Wan Norhayati Wan Salleh, Hamzah Fansuri, Taufik Qodar Romadiansyah, Agus Wedi Pratama

“…The highest N2/CH4 selectivity (6.29, 253 % increase) was observed with the 1:0.10 composition. …”
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First-principles insights into Sn/Sc/Ag/Ni-doped Al2Cu structural, electronic, mechanical, and thermodynamic properties by Yuhua Jin, Sijun Yang, Xuefeng Lu, Yu Ni, xiao Li

“…It proposes integrated electronic-mechanical-thermodynamic criteria for element selection under high-temperature service conditions, while validating critical alloy design parameters via Sc-doped instability cases, providing theoretical guidance for developing heat-resistant copper-aluminum composites.…”
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Quantitative determination of the components of the mixture – ear drops “Melavet” by the method of high-performance liquid chromatography by V. V. Parchenko, D. Datsiuk, V. Hunchak, V. Martynyshyn

“…During the research, a highly sensitive technique for the simultaneous determination of the components of the model mixture “Melavet” ear drops 10 ml by the method of high-performance liquid chromatography was developed. The optimal conditions for the simultaneous determination of the components of the mixture in one sample are selected. …”
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How spatial resolution mediates canopy spectral diversity as a proxy for marsh plant diversity by Yi Fu, Yunlong Yao, Lei Wang, Huaihu Yi, Yuanqi Shan

“…Spectral reflectance variations comprehensively capture differences in the biochemical composition and morphological characteristics among plant species, making them a promising approach for monitoring and estimating plant diversity. …”
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Unraveling the synergistic influence of Nb, V, and Ce on corrosion and high temperature performance of austenitic alloys by J. Ramirez, F. Zuñiga, S. Shiva Samhitha, Srivathsava Surabhi, A. Ríos R, J.P. Sanhueza, A.F. Jaramillo, A.G. Onate, M.F. Meléndrez, D. Rojas

“…Thermodynamic modeling (Thermo-Calc) was employed to optimize the composition, and their production was carried out from stainless steel scrap and ferroalloys in the open atmosphere induction melting process to contribute to the circular economy. …”
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