Association between the immune-inflammation indicators and osteoarthritis - NHANES 1999–2018 by Yan Xue, Cheng Chang, Yajun Chen, Lang Jia, Han Wang, Zaoyang Liu, Jiang Xie

“…Methods: Extracted NHANES data (1999–2018) and selected a study population based on demographic, examination, and laboratory data. …”
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Pharmacokinetics of infigratinib and its active metabolites in Chinese patients with advanced gastric cancer harboring FGFR2 gene amplification by Jiajia Yuan, Lin Shen, Tian Shu Liu, HuiTing Xu, Jianwei Yang, Jia Wei, Haiping Jiang, Yanhong Deng, Hongming Pan, Yusheng Wang, Xiaotian Zhang, Zhi Peng, Changsong Qi, Lingli Zhang, Peiwen Hsu, Lin Song, Lei Mu, Qiao Sun, Jifang Gong, Cheng Lyu

“…Abstract Infigratinib, an FGFR1‐3 selective oral tyrosine kinase inhibitor, has shown clinical activity in cancers with FGFR alterations. …”
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Gravitational-wave Kicks Impact the Spins of Black Holes from Hierarchical Mergers by Angela Borchers, Claire S. Ye, Maya Fishbach

“…However, gravitational-wave kicks can eject remnants from their host environments, meaning only retained black holes can participate in subsequent mergers. We calculate the spin distribution of retained black holes in typical globular clusters, accounting for remnant kick velocities. …”
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Hypolipidemic Activity of the Polysaccharide L-rhamnopyranosyl-6-O-methyl-galacturonan in Combined Administration with HMG-CoA Reductase and Cholesterol Absorption Inhibitors by E. E. Buyko, V. V. Ivanov, O. A. Kaidash, O. Yu. Rybalkina, E. A. Kiseleva, S. V. Krivoshchekov, T. L. Kiseleva, A. M. Guriev, M. V. Belousov

“…Dyslipidemia treatment in many cases requires carefully selected combination of lipid-lowering drugs including bile acid sequestrants. …”
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Risk factors and an interpretability tool of in-hospital mortality in critically ill patients with acute myocardial infarction by Rui Yang, Tao Huang, Renqi Yao, Di Wang, Yang Hu, Longbing Ren, Shaojie Li, Yali Zhao, Zhijun Dai

“…The SHapley Additive exPlanations (SHAP) values were calculated to evaluate the feature’s importance. The SHAP plots were adopted to explain and interpret the results. …”
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Gut markers for metastatic melanoma receiving immunotherapy by Guoping Ou, Juhua Gou, Hongmu Ou, Hailin Zheng, Yuanying Zhu, Jingjing Li, Xiaohua Liu

“…Markers for Cox prediction model were selected according to the results of HR, VIF and LASSO regression. …”
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Nucleation kinetics, FTIR, DFT and Hirshfeld surface analysis of sodium hydrogen oxalate hydrate (NaHC2O4∙H2O) single crystal by Ramki Chakaravarthy, S. Suresh, R. Gomathi, Yirong Geng, Wei Ren, R. Ezhil Vizhi

“…For recrystallization, a few excellent and faultless seed crystals were selected and a transparent single crystal of NaHC2O4∙H2O measuring 18 × 10 × 5 mm3 was formed in 15 days. …”
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Molecular insights into antibiofilm inhibitors of Streptococcus mutans glucosyltransferases through in silico approaches by Lubna Atta, Ali Raza Siddiqui, Mamona Mushtaq, Sajida Munsif, Mohammad Nur-e-Alam, Aftab Ahmed, Zaheer Ul-Haq

“…Furthermore, MM/PBSA free energy calculations identified Compound V as the most favorable binder, with a binding free energy of −24.20 kcal/mol. …”
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Phenotyping in Green Lettuce Populations Through Multispectral Imaging by Jordhanna Marilia Silva, Ana Carolina Pires Jacinto, Ana Luisa Alves Ribeiro, Isadora Rodrigues Damascena, Livia Monteiro Ballador, Paulo Henrique Lacerra, Pablo Forlan Vargas, George Deroco Martins, Renata Castoldi

“…In breeding programs, selecting genotypes with high agronomic potential is essential to meet market demands and cultivation conditions. …”
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Extracellular vesicle digital scoring assay for assessment of treatment responses in hepatocellular carcinoma patients by Chen Zhao, Yi-Te Lee, Andrew Melehy, Minhyung Kim, Jacqueline Ziqian Yang, Ceng Zhang, Jina Kim, Ryan Y. Zhang, Junseok Lee, Hyoyong Kim, Yong Ju, Yuan-Jen Tsai, Xianghong Jasmine Zhou, Steven-Huy B. Han, Saeed Sadeghi, Richard S. Finn, Sammy Saab, David S. Lu, Jason Chiang, Jae-Ho Park, Todd V. Brennan, Steven A. Wisel, Manaf Alsudaney, Alexander Kuo, Walid S. Ayoub, Hyunseok Kim, Hirsh D. Trivedi, Yun Wang, Aarshi Vipani, Irene K. Kim, Tsuyoshi Todo, Justin A. Steggerda, Georgios Voidonikolas, Kambiz Kosari, Nicholas N. Nissen, Rola Saouaf, Amit G. Singal, Myung Shin Sim, David A. Elashoff, Sungyong You, Vatche G. Agopian, Ju Dong Yang, Hsian-Rong Tseng, Yazhen Zhu

“…Results HCC EV TR Scores, calculated from pre- and post-treatment plasma samples in the phase-2 case–control study, accurately differentiated post-treatment viable from nonviable HCC in the training (area under the ROC curve [AUROC] of 0.90, n = 49) and validation set (AUROC of 0.88, n = 51). …”
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Exploring the genomic potential of Kytococcus schroeteri for antibacterial metabolites against multi-drug resistant Mycobacterium tuberculosis by Fatiha Khan, Deng Li, Iqra Ahmad, Sumra Wajid Abbasi, Umar Nishan, Sheheryar Sheheryar, Arlindo Alencar Moura, Riaz Ullah, Mohamed A. Ibrahim, Mohibullah Shah, Wangshu Li

“…The RMSD, RMSF, and binding energy calculations indicated a stable interaction of the ligand with the receptor protein, which raised the possibility of novel drugs to combat antibiotic resistance. …”
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A facile approach for fabricating g-C3N4-based materials as metal-free photocatalysts by Monika Michalska, Jiri Pavlovsky, Eva Scholtzova, Peter Skorna, Vlastimil Matejka, Kamil Bochenek, Amrita Jain, Koki Chida, Takeharu Yoshii, Hirotomo Nishihara

“…Furthermore, theoretical calculations utilizing the Density Functional Theory (DFT) method were conducted to reinforce the experimental findings of the research. …”
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Ecotoxicity of lanthanides to Daphnia magna: insights from elemental behavior and speciation in a standardized test medium by Vignati, Davide A.L., Martin, Loïc A., Poirier, Laurence, Zalouk-Vergnoux, Aurore, Fouque, Chantal, Bojic, Clément, Hissler, Christophe, Cossu-Leguille, Carole

“…Thermodynamic speciation calculations confirm the possible formation of insoluble species, mainly LN carbonates. …”
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UNIPDES - An internet-based transdiagnostic intervention for college students’ psychological symptoms: Evaluation of its development, usability and effectiveness: Study protocol by Ömer Özer, Gizem Öztemür, Ali Ercan Altinöz, Burak Köksal, Uğur Doğan, Sedat Batmaz, Recep Gür, Ahmet Altinok

“…This protocol was created to assist college students in overcoming these obstacles and to assess, in comparison to a control group, the impact of a guided and unguided online intervention platform based on transdiagnostic CBT (UNIPDES) on depression, anxiety, and adjustment levels. The calculated sample size for the study will include 330 students, and the participants will be selected from five different universities located in Türkiye. …”
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A New Framework to Reduce Doctor’s Workload for Medical Image Annotation by Yang Deng, Yao Sun, Yongpei Zhu, Yue Xu, Qianxi Yang, Shuo Zhang, Zhanyu Wang, Jirang Sun, Weiling Zhao, Xiaobo Zhou, Kehong Yuan

“…First, by combining active learning and U-shape network, we employed a suggestive annotation strategy to select the most effective annotation candidates. We then exploited a fine annotation platform to alleviate annotating efforts on each candidate and utilized a new criterion to quantitatively calculate the efforts of doctors. …”
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Evaluation of Hookworm Diagnosis Techniques from Patients in Debre Elias and Sanja Districts of the Amhara Region, Ethiopia by Ayalew Jejaw Zeleke, Ayenew Addisu, Adane Derso, Yalewayker Tegegne, Meseret Birhanie, Tekeba Sisay, Mulugeta Aemero

“…The study subjects were selected conveniently. After the data was entered into Statistical Package for the Social Sciences (SPSS), sensitivity, specificity, predictive values, test accuracy, and agreement of the different hookworm diagnosis methods, namely, test tube flotation technique (TFT), McMaster (MM), formol-ether concentration (FEC), Kato-Katz (KK), and direct wet mount microscopy (DWMM), were calculated by using SPSS software. …”
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Intratumoral and peritumoral radiomics signature based on DCE-MRI can distinguish between luminal and non-luminal breast cancer molecular subtypes by Hao Xu, Ao Yang, Min Kang, Hua Lai, Xinzhu Zhou, Zhe Chen, Libo Lin, Peng Zhou, Heping Deng

“…The LASSO method was then used for selecting features, and the radiomic score (radscore) for each patient was calculated. …”
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Metal Clusters: Between Atom and Bulk by Ernst Schumacher, Fritz Blatter, Martin Frey, Uli Heiz, Ursula Röthlisberger, Martin Schär, Arthur Vayloyan, Chahan Yeretzian

“…Furthermore guidance of the experimental work by quantumchemical calculations, molecular dynamics simulations, and the combination of the two are important because «chemical intuition» does not lead far in a field where chemical thinking has barely begun to develop: The molecular science of metals! …”
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Computationally Efficient Hybrid Downscaling of Surf Zone Hydrodynamics: Methodology and Evaluation by E. R. Echevarria, S. Contardo, B. Pérez‐Díaz, R. K. Hoeke, B. Leighton, C. Trenham, L. Cagigal, F. J. Méndez

“…Abstract We present a hybrid surf‐zone model that combines numerical simulations and statistical/machine learning techniques, enabling accurate calculations of nearshore wave and hydrodynamic parameters with high computational efficiency. …”
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Effects of Anisotropic Microstructure and Load Ratio on Fatigue Crack Propagation Rate in Additively Manufactured Ti-6Al-4V Alloy by Elad Chakotay, Roni Z. Shneck, Oz Golan, Rami Carmi, Mor Mega, Igal Alon, Raziel Yakov, Arie Busiba

“…Additive manufacturing (AM) refers to advanced technologies for building 3D objects by adding material layer upon layer using either electron beam melting (EBM) or selective laser melting. AM allows us to produce lighter and more complex parts. …”
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