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generalllte » generallllte (Expand Search), generatelllte (Expand Search)
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Fecal microbiota transplantation restores gut microbiota diversity in children with active Crohn’s disease: a prospective trial
Published 2025-03-01“…The combination of these six functional genera distinguished healthy children from those with CD (area under the curve = 0.96). …”
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The duodenal mucosa associated microbiome, visceral sensory function, immune activation and psychological comorbidities in functional gastrointestinal disorders with and without se...
Published 2022-12-01“…Frequently, patients with functional gastrointestinal disorders (FGIDs) report intolerance of wheat products. …”
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Gastric microbiome composition in obese patients and normal weight subjects with functional dyspepsia
Published 2024-06-01“…Results: There was no significant difference in the α-diversity scores, while distinct gastric microbial compositions were detected in both groups. …”
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Loquat-tea intercropping enhances rhizosphere microbial diversity and functional profiles in tea soil ecosystems
Published 2025-08-01“…The analysis of community differences showed that unclassified_c_acidobacteria was in pp_cs group, demonstrating the highest LDA score (4.4 score). Functional annotation via the Kyoto Encyclopedia of Genes and Genomes (KEGG) revealed that metabolic pathways were predominant across all treatments, with 36,111,608 reads assigned to metabolism. …”
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Linking dietary fiber to human malady through cumulative profiling of microbiota disturbance
Published 2025-02-01“…By leveraging microbiota disturbance similarities, we (1) classified 32 types of dietary fibers into six functional subgroups, revealing correlations with fiber solubility; (2) established associations among 161 diseases, uncovering shared microbiota disturbance patterns that explain disease co‐occurrence (e.g., type II diabetes and kidney diseases) and distinct microbiota patterns that discern symptomatically similar diseases (e.g., inflammatory bowel disease and irritable bowel syndrome); (3) designed a body‐site‐specific microbiota disturbance scoring scheme, computing a disturbance score (DS) for each disease and highlighting the pronounced capacity of Crohn's disease to disturb gut microbiota (DS = 14.01) in contrast with food allergy's minimal capacity (DS = 0.74); (4) identified 1659 fiber‐disease associations, predicting the potential of dietary fiber to modulate specific microbiota changes associated with diseases of interest; (5) established murine models of inflammatory bowel disease to validate the preventive and therapeutic effects of arabinoxylan that notably perturbed the Bacteroidetes and Firmicutes phyla, as well as the Bacteroidetes and Lactobacillus genera, aligning with our model predictions. …”
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Clinical correlation between intestinal flora profiles and the incidence of postmenopausal osteoporosis
Published 2025-12-01“…Purpose This study aimed to explore the characteristics of intestinal microflora polymorphism in postmenopausal women, and to determine the pathophysiological changes of gene polymorphism of intestinal flora and bone metabolism in postmenopausal osteoporosis (PMOP) patients.Methods A total of 104 postmenopausal women with PMOP or normal bone density were included. Lifestyle, hip T-score, bone metabolism indexes (25(OH)D, PTH, β-CTX, PINP), intestinal mucous membrane barrier function (diamine oxidase, D-lactic acid, LPS), gene polymorphisms, and characteristics of gut microbiota were examined.Results Women with PMOP had reduced physical activity, less dietary protein and calcium intake, lower levels of 25(OH)D, hip T-score, and BMD, but PMOP group had increased total energy and fat intake, and higher levels of PTH, β-CTX, diamine oxidase, D-lactic acid, and LPS (p < .05 for all), as compared with normal subjects. …”
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Dietary resistant starch protects against post-antibiotic intestinal damage by restoring microbial homeostasis and preserving intestinal barrier function in meat duck
Published 2025-07-01“…Additionally, RS inclusion enriched beneficial bacterial genera, including Coprobacter, Odoribacter, and Faecalibacterium (LDA score > 3). …”
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Dietary supplementation with Bacillus subtilis PB6 alleviates diarrhea and improves growth performance and immune function in weaned piglets fed a high-protein diet
Published 2025-02-01“…This study aimed to evaluate the effects of dietary supplementation with Bacillus subtilis PB6 on growth performance, diarrhea scores, nutrient digestibility, immune function, and gut microbiota in weaned piglets fed a high-protein diet. …”
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Distinct gut microbiota profiles and network properties in older Korean individuals with subjective cognitive decline, mild cognitive impairment, and Alzheimer’s disease
Published 2025-08-01“…All three groups shared 71 common bacterial genera with distinct taxonomic profiles across cognitive states. …”
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Gut dysbiosis is associated with increased blood–brain barrier permeability and cognitive impairment in elderlies with coronary heart disease
Published 2025-08-01“…Hippocampal BBB permeability (Ktrans) was significantly elevated in MCI patients (6.04 ± 3.02 vs. 3.90 ± 1.03 × 10−3 min−1, p = 0.006) and inversely correlated with the relative abundance of Faecalibacterium (Spearman’s r = −0.466, p = 0.002) and Oscillospira (Spearman’s r = −0.322, p = 0.043). Conversely, these genera showed positive correlations with Montreal Cognitive Assessment-Basic (MoCA-B) scores (Faecalibacterium: r = 0.596, p < 0.001; Oscillospira: r = 0.369, p = 0.019).ConclusionElderlies with CHD and MCI demonstrate significant gut dysbiosis, characterized by reduced microbial diversity and depletion of SCFA-producing taxa, notably butyrate producers. …”
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肠道微生物群紊乱与急性轻型缺血性卒中患者不良功能预后的相关性研究 Correlation between Gut Microbiota Dysbiosis and Poor Functional Prognosis in Patients with Acute Mild Ischemic Stroke...
Published 2024-12-01“…Abstract: Objective To investigate the relationship between gut microbiota and clinical prognosis in acute mild ischemic stroke (MIS) patients by establishing a cohort of patients with MIS, and to identify intervention targets for poor functional prognosis. Methods Patients with acute MIS (NIHSS score≤5 points) were prospectively and continuously enrolled in this study. …”
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Gut microbiota in chronic obstructive pulmonary disease varies by CT-verified emphysema status
Published 2025-12-01“…Nine of these genera belonged to the family Lachnospiraceae. Lung function, blood counts and COPD assessment test score correlated with several genera’s relative abundance. …”
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Effect of Dendrobium Officinale on Radioactive Oral Mucositis of Nasopharyngeal Carcinoma and Changes of Oral Microecology
Published 2025-01-01“…The use of Dendrobium officinale in nasopharyngeal carcinoma patients with radiotherapy-induced oral mucositis showed little difference in microbial diversity and abundance, but there were significant differences among oral bacteria genera. Conclusions: Dendrobium officinale is effective in the treatment of radiotherapy-induced oral mucositis, which may be related to the improvement of salivary gland function and regulation of the oral microenvironment. …”
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Assessment of metal residues in soil and evaluate the plant accumulation in copper mine tailings of Dongchuan, Southwest China
Published 2025-02-01“…Salix balfouriana with the highest comprehensive membership function score of 5.298 was identified as the preferred species for ecological restoration in the Dongchuan Cu tailing area. …”
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Research on gut microbiota characteristics of PBC patients at different ALBI grades based on machine learning
Published 2024-11-01“…BackgroundThe Albumin-Bilirubin (ALBI) score and grade are widely used to stratify patients with primary biliary cholangitis (PBC) into different disease statuses and risk levels. …”
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Growth performance and gut health of nursery pigs fed diet containing sodium butyrate or enzymatically hydrolyzed yeast product
Published 2025-03-01“…Dietary EYP increased (P < 0.05) the relative abundance of Sporobacter and Desulfovibrio genera in the cecum. Dietary EYP increased (P < 0.05) the relative abundance of Verrucomicrobia phylum and Odoribacter, Enterococcus, and YRC22 genera in feces. …”
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AIpollen: An Analytic Website for Pollen Identification Through Convolutional Neural Networks
Published 2024-11-01“…For the optimization algorithm, we opted for the Adam optimizer and utilized the cross-entropy loss function. Additionally, we implemented ELU activation function, data augmentation, learning rate decay, and early stopping strategies to enhance the training efficiency and generalization capability of the model. …”
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Circadian rhythm perturbation causes IBS-like characteristics and altered fecal metabolome in mice
Published 2025-05-01“…Abstract Background Circadian rhythm disturbance is associated with functional gastrointestinal disorders such as irritable bowel syndrome (IBS). …”
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Distinct gut microbiota and metabolomic profiles in HBV-related liver cirrhosis: insights into disease progression
Published 2025-05-01“…Genera such as Alistipes and Lachnospira were notably depleted, while Fusobacterium and Enterococcus were enriched in patients with Model for End-Stage Liver Disease (MELD) scores ≥ 21 or Child-Turcotte-Pugh C grade. …”
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