Effects of sedatives on diaphragm activity monitored by ultrasound: a systematic review and meta-analysis by Jiaren Luo, Luhao Wang, Bilin Wei, Zhikun Huang, Huifang Zheng, Bin Gu, Fei Pei, Zenan Chang, Yang Liu, Xiangdong Guan, Xuyu Zhang, Zimeng Liu

“…This meta-analysis aims to launch this problem by systematically analyzing the available evidence. Methods The EMBASE, PubMed, and Web of Science databases were searched. …”
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The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Project Cohort and Biobank from 2010 Through 2023—A Cohort Profile Update by Kristensen FPB, Nicolaisen SK, Nielsen JS, Christensen DH, Højlund K, Beck-Nielsen H, Rungby J, Friborg SG, Brandslund I, Christiansen JS, Vestergaard P, Jessen N, Olsen MH, Andersen MK, Hansen T, Brøns C, Vaag A, Thomsen RW, Sørensen HT

“…Median T2DM duration at enrollment was 1.3 years, and median BMI was 31.6 kg/m2 for women and 30.5 kg/m2 for men. 18.3% were smokers, 5.7% consumed more than 14/21 units of alcohol weekly (women/men), and 17.9% reported leisure-time physical inactivity. …”
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Effectiveness of Group Problem Management Plus, a brief psychological intervention for adults affected by humanitarian disasters in Nepal: A cluster randomized controlled trial. by Mark J D Jordans, Brandon A Kohrt, Manaswi Sangraula, Elizabeth L Turner, Xueqi Wang, Pragya Shrestha, Renasha Ghimire, Edith Van't Hof, Richard A Bryant, Katie S Dawson, Kedar Marahatta, Nagendra P Luitel, Mark van Ommeren

“…Our objective was to test the effectiveness of a brief group psychological treatment delivered by trained facilitators without prior professional mental health training in a disaster-prone setting.<h4>Methods and findings</h4>We conducted a cluster randomized controlled trial (cRCT) from November 25, 2018 through September 30, 2019. …”
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Malformaciones pulmonares congénitas: ¿Qué impacto tiene la presencia de síntomas preoperatorios en el resultado quirúrgico? by María López-Díaz, Ester Fernández Díaz, Indalecio Cano Novillo, Elena Bergón, Rocío Morante Valverde, Alberto Galindo Izquierdo, Juan L. Antón-Pacheco

“…Conclusions: Postoperative complications were not significantly more frequent in the symptomatic group of patients. …”
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Effects of ginger supplementation in individuals with mild to moderate joint pain I: ratings of pain, functional capacity, and markers of inflammation by Jacob Broeckel, Landry Estes, Megan Leonard, Broderick Dickerson, Drew E. Gonzalez, Martin Purpura, Ralf Jäger, Ryan Sowinski, Christopher J. Rasmussen, Richard B. Kreider

“…The purpose of this study was to determine whether a specialized ginger extract effects pain perception, functional capacity and markers of inflammation.Methods 30 men and women (56.0 ± 9.0 years, 164.4 ± 14 cm, 86.5 ± 20.9 kg, 31.0 ± 7.5 kg/m2) with a history of mild to severe joint and muscle pain and inflammation participated in a randomized, placebo-controlled, parallel-arm, intervention trial. …”
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Ecofriendly colorimetric indicators for freshness monitoring of sliced mango fruit (Mangifera indica L.) by Fikrte Woldeyes Hailu, Solomon Workneh Fanta, Alemayehu Ambaw Tsige, Mulugeta Admasu Delele

“…In addition, linkages between indicators and fruit quality parameters were examined. Methods Mangoes cv. ‘Keitt’ used Intelligent indicators Three indicators were developed from filter paper and anthocyanin from butterfly pea flower at 100% (BP), butterfly pea flower at 50% (BP7) and red cabbage at 100% (RC) For sample preparation, 150 g of cut mangoes were kept in polyethylene terephthalate trays with indicators and stored at 20 ± 2 °C and 40 ± 4% relative humidity for 3 days. …”
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Cognitive function and associations with demographic, socioeconomic, health and behavioural factors among older adult men and women in rural Bangladesh: a population-based cross-se... by Edward Fottrell, Harry Costello, Naveed Ahmed, Carina King, Sanjit Kumer Shaha, Tasmin Nahar, Malini Pires, Andrew Copas, Hassan Haghparast-Bidgoli, Joanna Morrison, Abdul Kuddus, Kishwar Azad

“…This study describes the burden of cognitive impairment and associations with demographic, health and behavioural factors among older adults in rural Bangladesh. Methods: We conducted a population-based cross-sectional study of a random sample of men and women aged 60 years and above in 96 rural villages in Bangladesh. …”
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Analysis of the Rights and Obligations of Stakeholders in China’s National Park Concession System by Le ZHONG, Zhicong ZHAO

“…Following the principle of equality of stakeholders’ rights and obligations, this research aims to provide a comprehensive theoretical and practical framework to guide ongoing research and the systematic construction of China’s national park concession system.MethodsThis research is designed to investigate the overarching and universal challenges associated with the establishment of the national park concession system in China. …”
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Congenital lung malformations: Do preoperative symptoms have an impact in surgical outcomes? by María López-Díaz, Ester Fernández Díez, Indalecio Cano Novillo, Elena Bergón, Rocío Morante Valverde, Alberto Galindo Izquierdo, Juan L. Antón-Pacheco

“…The aim of our study was to analyze the association of preoperative symptoms with surgical outcomes in patients with CLMs treated by means of minimally invasive surgery (MIS). Patients and methods: Retrospective study of patients with CLM treated with MIS in our hospital between 2003 and 2023. …”
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Prevalence, spermatozoa, hormonal, and genetic evaluation of rare mosaic klinefelter syndrome patients in southern China by Derong Li, Yuqing Lai, Yujuan Liao, Jinjie Pan, Yudi Luo, Yunning Liang, Bowen Luo, Lingling Zhu, Guosheng Deng, Xiang Li, Keng Feng, Feifei Lei, Liuping Lan

“…However, due to the low prevalence and limited sample size, more data is necessary to confirm these findings.…”
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Overtime Histological Changes in the Lungs after Intoxication with Baclofen Alone or in Combination with Ethanol (Experimental Study) by O. L. Romanova, M. L. Blagonravov, P. G. Dzhuvalyakov, V. I. Torshin, A. V. Ershov, E. Kh. Barinov

“…The aim of the study was to evaluate the overtime histological changes in the lungs after intoxication with baclofen alone or in combination with ethanol.Materials and methods. The experiment was carried out on 35 male Wistar rats weighing 290-350 g and aged 20 weeks. …”
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Efficacy and tolerability of Seizar (lamotrigine) in the treatment of epilepsy (experience of Svt. Luka’s Institute of Child Neurology and Epilepsy) by O. A. Pylaeva, K. Yu. Mukhin

“…Objective: to review efficacy and tolerability of Seizar in patients with various forms of epilepsy based on long-term experience of using this drug in our center. Materials and methods. We analyzed therapeutic effects of Seizar in 22 patients aged between 3 and 34 years (mean age 15.3 years) treated in Svt. …”
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Nonlinear Relationship Between the Elderly’s Perception of Green Spaces and Their Activity Characteristics by Yuanjing WU, Yongyi YOU, Wei ZHOU, Siren LAN

“…To address this gap, this research employs the extreme gradient boosting (XGBoost) model to investigate the nonlinear relationship between the elderly’s perception of urban park green spaces and their activity characteristics, aiming to inform age-friendly park design and evidence-based green space planning strategies.MethodsThis research is based on 779 valid questionnaires collected from five representative urban parks in Fuzhou, a city experiencing rapid demographic aging and urban expansion. …”
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Impacts of pre-pregnancy exposure to per- and polyfluoroalkyl substances on menstrual characteristics among women undergoing assisted reproductive technology by Huyi TAO, Yujie CAO, Yitao PAN, Jiuru ZHAO, Zhiwei LIU, Yu GAO, Ying TIAN

“…ResultsIn the pre-pregnancy serum samples of the study population, 15 PFAS were detected in more than 60% of the samples, including perfluoroheptanoic acid (PFHpA), perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), perfluoroundecanoic acid (PFUnDA), perfluorododecanoic acid (PFDoDA), perfluorobutanesulfonic acid (PFBS), perfluorohexanesulfonic acid (PFHxS), perfluoroheptanesulfonic acid (PFHpS), perfluorooctanesulfonic acid (PFOS), 6:2 chlorinated polyfluorinated ether sulfonate (6:2 Cl-PFESA), 8:2 chlorinated polyfluorinated ether sulfonate (8:2 Cl-PFESA), perfluoro-2-propoxypropanoic acid (HFPO-DA), perfluoro-2-methoxyacetic acid (PFMOAA), and perfluoro-(3,5,7,9,11-pentaoxadodecanoic) acid (PFO5DoDA). …”
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Antioxidant Effects of Curcumin on the Motility and Structural and Biochemical Parameters of Epididymal Sperm in Shal Rams after the Freezing-Thawing Process by Ramin Farhadi, Abbas Farshad, Jalal Rostamzadeh, Abouzar Najafi

“…The use of this technique requires sperm freezing, a process during which superior genes are widely expanded and more progeny can be obtained from a male animal with high genetic characteristics. …”
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Content and Occurrence State of Niobium and Rare Earth Elements in Hornblendite of Dagele, East Kunlun by the Electron Probe Technique by Jiandong LIU, Bingzhang WANG, Wufu LI, Tingting JIN, Xinyuan ZHANG, Chuntao WANG, Jinshan CAO, Ying ZHENG, Zhongguo ZHAO

“…The analyzed sample (21DGb11) of apatite-bearing phlogopite hornblendite is situated in the central region of the complex. …”
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Blood immunophenotyping of multiple sclerosis patients at diagnosis identifies a classical monocyte subset associated to disease evolution by Stéphane Rodriguez, Stéphane Rodriguez, Laura Couloume, Juliette Ferrant, Juliette Ferrant, Nicolas Vince, Marion Mandon, Marion Mandon, Rachel Jean, Rachel Jean, Celine Monvoisin, Simon Leonard, Simon Le Gallou, Simon Le Gallou, Nayane S. B. Silva, Nayane S. B. Silva, Sonia Bourguiba-Hachemi, David Laplaud, David Laplaud, Alexandra Garcia, Romain Casey, Romain Casey, Romain Casey, Romain Casey, Helene Zephir, Anne Kerbrat, Gilles Edan, Emmanuelle Lepage, Eric Thouvenot, Eric Thouvenot, Aurelie Ruet, Aurelie Ruet, Guillaume Mathey, Guillaume Mathey, Pierre-Antoine Gourraud, Pierre-Antoine Gourraud, Karin Tarte, Karin Tarte, Celine Delaloy, Patricia Amé, Patricia Amé, Mikael Roussel, Mikael Roussel, Laure Michel, Laure Michel, Laure Michel

“…IntroductionMyeloid cells trafficking from the periphery to the central nervous system are key players in multiple sclerosis (MS) through antigen presentation, cytokine secretion and repair processes.MethodsCombination of mass cytometry on blood cells from 60 MS patients at diagnosis and 29 healthy controls, along with single cell RNA sequencing on paired blood and cerebrospinal fluid (CSF) samples from 5 MS patients were used for myeloid cells detailing.ResultsMyeloid compartment study demonstrated an enrichment of a peculiar classical monocyte population in 22% of MS patients at the time of diagnosis. …”
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Interplay between tumor mutation burden and the tumor microenvironment predicts the prognosis of pan-cancer anti-PD-1/PD-L1 therapy by Wuyuan Liao, Wuyuan Liao, Wuyuan Liao, Xinwei Zhou, Xinwei Zhou, Hansen Lin, Hansen Lin, Zihao Feng, Zihao Feng, Xinyan Chen, Yuhang Chen, Yuhang Chen, Minyu Chen, Minyu Chen, Mingjie Lin, Mingjie Lin, Gaosheng Yao, Gaosheng Yao, Jinwei Chen, Jinwei Chen, Haoqian Feng, Haoqian Feng, Yinghan Wang, Yinghan Wang, Zhiping Tan, Zhiping Tan, Youyan Tan, Jun Lu, Jun Lu, Pengju Li, Pengju Li, Jinhuan Wei, Jinhuan Wei, Li Luo, Li Luo, Liangmin Fu, Liangmin Fu, Liangmin Fu

“…This study aimed to explore the complex interplay between TMB and the tumor microenvironment (TME) and to identify novel predictive biomarkers that can enhance the precision of ICI therapy across multiple cancer types.MethodsWe systematically collected and analyzed genomic and clinical data from patients receiving anti-PD-1/PD-L1 immunotherapy across multiple cohorts. …”
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Analyzing the Reproductive Characteristics of the Naked Carp Gymnocypris Przewalskii (Kessler) Based on the Oxygen Isotopes of Otolith Core Using SHRIMP by Ling ZHOU, Linbo QIAN, Sumei ZHAO, Xiulan ZHANG, Yinglie LIU, Qiaoling TANG, Jie YUAN

“…Otolith δ18O provides a method for fish population identification, migration and environment exploration of spawning ground. …”
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A significantly enhanced role for plant genetic resource centres in linking in situ and ex situ conservation to aid user germplasm access by Nigel Maxted, Anne-Françoise Adam-Blondon, Catherine Hazel Aguilar, Ana Maria Barata, Béla Bartha, Riccardo Bocci, Domenico De Paola, Heli S. Fitzgerald, Louis John Fresta, Pietro Fusani, Giovanni Giuliano, Filippo Guzzon, Philipp Holzherr, Vojtěch Holubec, José María Iriondo Alegría, Juozas Labokas, Lorenzo Maggioni, Joana Magos Brehm, Anna Palmé, Jade Phillips, Jaime Prohens, Lorenzo Raggi, Parthenopi Ralli, Dainis Rungis, Karuine Sarikyan, Jelka Šuštar-Vozlič, Imke Thormann, Goran Zdunić

“…The demand from breeders for a broader diversity is driving a more integrated approach that combines ex situ and in situ methods. …”
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