EXPERIMENTAL STUDY OF FURCATION AREA AND PROSPECTS OF ITS COMPLEX TREATMENT by Yu.V. Sidash, O.P. Kostyrenko, V.N. Petrushanko

“…A significant percentage of periodontitis occurs in the area of furcations of multi-rooted teeth, sometimes alone, but more often as combined with apical periodontitis. …”
Get full text

Identificación de personas a través del cotejo de radiografías panorámicas y periapicales. Comparación de características observadas en 30 pacientes Identification of people throug... by Clarisa Yanina Gómez, Pamela Borgo Cosentino, Alan Diego Briem Stamm

“…A comparison was conducted between AM and PM samples, in all cases confronting a panoramic radiograph with one or more periapical radiographs. …”

Identifying bellwether sewershed sites for sustainable disease surveillance in Bengaluru, India: a longitudinal studyResearch in context by Rebecca Fern Daniel, Subash K. Kannan, Namrta Daroch, Sutharsan Ganesan, Farhina Mozaffer, Vishwanath Srikantaiah, Lingadahalli Subrahmanya Shashidhara, Rakesh Mishra, Farah Ishtiaq

“…We aimed to identify ‘bellwether’ sewershed sites for sustainable disease surveillance in Bengaluru, India. Methods: We conducted this longitudinal study from December 2021 to January 2024 at 26 centralised sewershed sites in Bengaluru city (∼11 million inhabitants). …”
Get full text

A pilot study exploring long-read nanopore metagenomics sequencing for heteroresistance detection in clinical specimens by Miss Siphiwe Matukane, Miss Khensani Hattingh, Dr Kristien Nel Van Zyl, Dr Mae Newton-Foot, Prof Andrew Whitelaw

“…This study explored ONT sequencing and compared two analysis pipelines for detecting resistant bacterial subpopulations. Methods: Confirmed culture-negative, antibiotic-free, and E. coli DNA-free urine samples were pooled and spiked with well-characterised resistant and susceptible E. coli isolates to simulate 10%, 5%, and 2% heteroresistance. …”
Get full text

Sialyltransferase gene signature as a predictor of prognosis and therapeutic response in kidney renal clear cell carcinoma by Huiyu Liu, Changwei Zhou, Zaichun Yan, Hairong Yang, Yun Zhao, Rui Tian, Xuejun Bo, Leizuo Zhao, Wei Ren

“…This study aimed to develop a prognostic model based on sialyltransferase-related genes (SRGs) to predict the prognosis and treatment response of patients with KIRC. Methods We utilized RNA-Seq data of KIRC from The Cancer Genome Atlas (TCGA) database, selecting samples with survival data and clinical outcomes. …”
Get full text

Contamination risk and drug resistance analysis of Klebsiella pneumoniae in a medical institution in Minghang District， Shanghai， 2021‒2023 by ZHANG Sijia, ZHANG Xing, TIAN Liang, ZHOU Yibin, WEN Xiaosa, WANG Jing, XU Zhiyin, WU Min

“…ObjectiveTo investigate the contamination status, transmission risk and drug resistance of Klebsiella pneumoniae (KP) on the object surfaces in the surrounding environment of hospitalized patients infected with carbapenem-resistant Klebsiella pneumoniae (CRKP) , so as to provide a scientific guidance for the prevention and control of healthcare-associated infection.MethodsSamples from the surfaces of objects in the surrounding environment of CRKP infected patients living in the intensive care unit (ICU) and hand specimens from healthcare workers were collected for KP isolation and identification, as well as drug susceptible test in a medical institution located in Minhang District, Shanghai from 2021 to 2023. …”
Get full text

Comparison of Biocompatibility of 3D-Printed Ceramic and Titanium in Micropig Ankle Hemiarthroplasty by Si-Wook Lee, Donghyun Lee, Junsik Kim, Sanghyun An, Chul-Hyun Park, Jung-Min Lee, Chang-Jin Yon, Yu-Ran Heo

“…In micro-CT analysis, the adhesive tissue score of the ceramic artificial sample was better than that of the titanium sample (average threshold = 3027.18 ± 405.92). …”
Get full text

How to Implement Digital Clinical Consultations in UK Maternity Care: the ARM@DA Realist Review by Catrin Evans, Georgia Clancy, Kerry Evans, Andrew Booth, Benash Nazmeen, Candice Sunney, Mark Clowes, Nia Wyn Jones, Stephen Timmons, Helen Spiby

“…Phase 2 involved testing these theories by looking in-depth at more evidence. In phase 3, the quality and relevance of the evidence was assessed and more information gathered where necessary. …”
Get full text

Longitudinal correlates of quitting e-cigarettes in the United States by Mayank Sakhuja, Shayna Farris, Tara Licciardello Queen, Marissa G. Hall, Ebbie Kalan, Paschal Sheeran, Kurt M. Ribisl, Noel T. Brewer

“…To inform future programs and policies, we sought to identify longitudinal correlates of quitting e-cigarette use in the United States (US). Methods: The study design was longitudinal. A nationally representative sample of 1138 US adults and adolescents who used e-cigarettes took a baseline online survey between Nov 2022 and Jan 2023. …”
Get full text

Four 2×2 factorial trials of smartphone CBT to reduce subthreshold depression and to prevent new depressive episodes among adults in the community–RESiLIENT trial (Resilience Enhan... by Toshi A Furukawa, Pim Cuijpers, Tatsuo Akechi, Masaru Horikoshi, Yan Luo, Hisashi Noma, Takeo Nakayama, Helen Christensen, Naoki Kondo, Norito Kawakami, Aran Tajika, Ronald C Kessler, Shingo Fukuma, Masatsugu Sakata, Rie Toyomoto, James M S Wason

“…Guided internet cognitive–behavioural therapies (iCBT) appear promising but there is room for improvement because we do not yet know which of various iCBT skills are more efficacious than others, and for whom. In addition, there has been no platform for iCBT that can accommodate ongoing evolution of internet technologies.Methods and analysis Based on our decade-long experiences in developing smartphone CBT apps and examining them in randomised controlled trials, we have developed the Resilience Training App Version 2. …”
Get full text

Acupuncture treatment is associated with a decreased risk of dementia in patients with rheumatoid arthritis in Taiwan: A propensity-score matched cohort study by Hou-Hsun Liao, Ming-Cheng Huang, Yu-Chen Lee, Cheng-Li Lin, Mei-Yao Wu, Peter Karl Mayer, Hung-Rong Yen

“…Background: The purpose of this study was to understand whether acupuncture can decrease the risk of dementia in patients with rheumatoid arthritis (RA). Methods: Using the registry from the National Health Insurance Research Database of Taiwan, we carried out a 1:1 propensity-score matched cohort study to analyze patients with RA diagnosed between 2000 and 2010. …”
Get full text

Bacterial diversity in longan orchard alluvial soil is influenced by cultivation time and soil properties by Nguyen Khoi Nghia, Kovacs Emoke Dalma, Kovacs Melinda Haydee, Le Thi Xa, Lois Wright Morton, Hüseyin Barış Tecimen, Javad Robatjazi, Jegan Sekar, Hendra Gonsalve W. Lasar, Trung Thanh Nguyen, Nguyen Minh Phuong, Chau Thi Anh Thy, Do Thanh Luan, Nguyen Thi Kieu Oanh

“…This study investigated the structure of soil bacterial communities and their associations with soil physicochemical properties in longan orchards.MethodsSoil samples were collected from longan orchards cultivated for 15 (N15), 20 (N20) and 30 years (N30) in Vinh Long Province, Vietnam. …”
Get full text

Expectations regarding regenerative medicine and attitudes toward invasive surgical therapies in patients with Parkinson’s disease: A cross-sectional survey by Mika Watabe, Atsushi Shima, Kiyoaki Takeda, Yuta Terada, Yusuke Sakato, Akira Nishida, Ikko Wada, Haruhi Sakamaki-Tsukita, Kenji Yoshimura, Daisuke Kambe, Koji Furukawa, Masanori Sawamura, Etsuro Nakanishi, Yosuke Taruno, Hodaka Yamakado, Ryosuke Takahashi, Nobukatsu Sawamoto

“…Allogeneic iPS cells are considerably more practical, despite potential concerns regarding tumor formation post-transplantation. …”
Get full text

Accelerometer-derived physical activity patterns and incident type 2 diabetes: a prospective cohort study by Dan-Qing Liao, Hao-Jie Chen, Hong-Min Li, Jian Gao, Xu-Lian Tang, Li-Ying Du, Shu-Min Lai, Wen-Fang Zhong, Hong-Xuan Huang, Zhi-Yuan Xiong, Pei-Liang Chen, Ling Kuang, Bing-Yun Zhang, Jin Yang, Qing-Mei Huang, Dan Liu, Pei-Dong Zhang, Chen Mao, Zhi-Hao Li

“…However, the association between the “weekend warrior” (WW) pattern—characterized by concentrated moderate-to-vigorous PA (MVPA) over one to two days—and T2D remains unclear. Methods This prospective cohort study aims to utilize device-measured PA data to investigate the associations between PA patterns and T2D. …”
Get full text

Single‐cell RNA‐sequencing and spatial transcriptomic analysis reveal a distinct population of APOE− cells yielding pathological lymph node metastasis in papillary thyroid cancer... by Guohui Xiao, Rongli Xie, Jianhua Gu, Yishu Huang, Min Ding, Dongjie Shen, Jiqi Yan, Jianming Yuan, Qiong Yang, Wen He, Siyu Xiao, Haizhen Chen, Dan Xu, Jian Wu, Jian Fei

“…Abstract Background Thyroid cancer is one of the most common endocrine tumors worldwide, especially among women and the metastatic mechanism of papillary thyroid carcinoma remains poorly understood. Methods Thyroid cancer tissue samples were obtained for single‐cell RNA‐sequencing and spatial transcriptomics, aiming to intratumoral and antimetastatic heterogeneity of advanced PTC. …”
Get full text

Applicability of a serodiagnostic line blot for idiopathic inflammatory myopathy: the muscle biopsy is not all by Pedro Nogueira Fontana, Pedro Nogueira Fontana, Vinícius Gomes da Silva, Roseli Corazzini, Natália Merten Athayde, Ana Marina Dutra Ferreira da Silva, Igor Brockhausen, Carolina da Cunha Correia, Cláudia Ferreira da Rosa Sobreira, Pedro José Tomaselli, Flávio Petean, Rodrigo de Oliveira, Pablo Vinícius Feitoza, Michel Moraes Soane, Natália Saraiva, Rafaela Hidalgo, Cláudia Fideles, David Feder, Alzira Alves de Siqueira Carvalho

“…While MSAs are considered specific for their respective IIM subclass, MAAs can be present in more than one subclass and in other conditions. This study compares results of a multispecific line blot assay with the final diagnosis of IIM patients based on clinical features and muscle biopsy to draw conclusions for the test's applicability in the diagnostic workflow.MethodsSamples from patients (n = 50) diagnosed with various forms of IIM, including patients (n = 5) with other myopathies, were analyzed using the EUROLINE Autoimmune Inflammatory Myopathies 16 Ag (IgG), an anti-HMGCR (IgG) line blot, and the Anti-cN-1A ELISA (IgG, all EUROIMMUN).ResultsMSA and MAA were detected in 74.0% (37/50) of sera and were concordant with the final diagnosis in 64.8% (24/37), discordant in 16.2% (6/37) and not evaluable in 18.9% (7/37) of cases. …”
Get full text

A systematic review of the predictive factors for the recurrence of acute pancreatitis by Daniela Pacella, Adriano De Simone, Adolfo Pisanu, Gianluca Pellino, Lucio Selvaggi, Valentina Murzi, Eleonora Locci, Giulia Ciabatti, Laura Mastrangelo, Elio Jovine, Matteo Rottoli, Giacomo Calini, Stefano Cardelli, Fausto Catena, Carlo Vallicelli, Raffaele Bova, Gabriele Vigutto, Fabrizio D’Acapito, Giorgio Ercolani, Leonardo Solaini, Alan Biloslavo, Paola Germani, Camilla Colutta, Pasquale Lepiane, Rosa Scaramuzzo, Savino Occhionorelli, Domenico Lacavalla, Maria Grazia Sibilla, Stefano Olmi, Matteo Uccelli, Alberto Oldani, Alessio Giordano, Tommaso Guagni, Davina Perini, Francesco Pata, Bruno Nardo, Daniele Paglione, Giusi Franco, Matteo Donadon, Marcello Di Martino, Salomone Di Saverio, Luca Cardinali, Grazia Travaglini, Dario Bruzzese, Mauro Podda

“…Analyzing the risk factors that may contribute to the recurrence of Biliary and Alcoholic Pancreatitis (BAP and AAP), future research can be driven toward new solutions for preventing and treating this pancreatic disease. Methods A systematic review was conducted selecting studies from BiomedCentral, PubMed, Scopus and Web of Science by two independent reviewers. …”
Get full text

Learning together for mental health: feasibility of measures to assess a whole-school mental health and wellbeing intervention in secondary schools by Oliver Lloyd-Houldey, Joanna Sturgess, Neisha Sundaram, Steven Hope, Semina Michalopoulou, Elizabeth Allen, Lee Hudson, Stephen Scott, Dasha Nicholls, Deborah Christie, Rosa Legood, Chris Bonell, Russell Viner

“…Design and methods We conducted a feasibility study which included assessment of the indicative primary and secondary outcomes measures and procedures to be used in a future Phase III trial. …”
Get full text

RETRACTED: Identification of novel candidate targets for suppressing ovarian cancer progression through IL-33/ST2 axis components using the system biology approach by Geovanny Genaro Reivan Ortiz, Carmen Iulia Ciongradi, M. V. N. L. Chaitanya, Jayasankar Narayanan, Mohamed Mohany, Salim S. Al-Rejaie, José Luis Arias-Gonzáles, Ioan Sârbu, Marjan Assefi, Shaik Vaseem Akram, Yusuf Döğüş, Abolfazl Bahrami, Reza Akhavan-Sigari, Reza Akhavan-Sigari

“…IL-33/ST2 signaling has drawn a lot of attention since it acts as a pro-tumor alarmin and encourages spread by altering TM.Methods: Differentially expressed genes (DEGs) of the OvC tumor microenvironment were found in the GEO database, qRT-PCR, western blotting, and immunohistochemistry, and their presence and changes in healthy and tumor tissue content were examined. …”
Get full text

Usefulness of Combining NT-proBNP Level and Right Atrial Diameter for Simple and Early Noninvasive Detection of Pulmonary Hypertension Among Adult Patients with Atrial Septal Defec... by Anggoro Budi Hartopo, Dyah Wulan Anggrahini, Muhammad Gahan Satwiko, Arditya Damarkusuma, Armalya Pritazahra, Muhammad Reyhan Hadwiono, Vera Christina Dewanto, Salvatore Di Somma, Noriaki Emoto, Lucia Kris Dinarti

“…The objective of this study is to assess the value of NT-proBNP, along with simple TTE parameter, to screen PH among adults with ASD. Methods: This was a cross-sectional study. The subjects were adult ASD-PH patients from the COHARD-PH  registry (n=357). …”
Get full text