Barium Abundances of Common Stars in the Gaia-ESO Survey and the LAMOST Medium-resolution Survey by Tian-Yi Chen, Jian-Rong Shi, Hong-Liang Yan, Shuai Liu, Chun-Qian Li, Xiao-Jin Xie, Ze-Ming Zhou, Yao-Jia Tang, Ming-Yi Ding

“…We derive the Ba abundances from three Ba ii absorption lines at λλ 5853, 6141, and 6496 Å of R = 47,000 UVES spectra through the spectral synthesis method using the local thermodynamic equilibrium (LTE) and NLTE assumptions. …”
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Safety, Adequacy, and Accuracy of Transvaginal Ultrasound-Guided Tru-Cut Biopsy of Gynaecologic Tumours: A Retrospective Single-Centre Study by Munachiso Iheme Ndukwe, Dominik Karasek, Denisa Pohanková, Ivan Praznovec, Petra Bretova, Martin Stepan, Dominik Habes, Jan Laco, Akaninyene Eseme Ubom, Milan Vosmik, Igor Sirak

“…<b>Objective:</b> To evaluate the safety, adequacy, and accuracy of tru-cut biopsy of gynaecologic tumours in a population of Czech women. <b>Methods:</b> A four-year retrospective study of ultrasound-guided tru-cut biopsy of gynaecologic tumours was conducted in the Department of Obstetrics and Gynaecology, Charles University, Hradec Kralove, Czech Republic. …”
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Microbiological profile and antibiotic susceptibility of body fluids or swabs of acute leukemia patients with sepsis in a tertiary care hospital by Arka Karmakar, Atreyi Chakraborty, Krishnendu Bandyopadhyay, Biswajit Biswas, Sankar Kumar Das, Atanu Roy, Sayan Chatterjee, Mayank K Vidyarthi, Chayanik Ghosh, Pradip K Bej, Jeker Ali, Akashleena Datta

“…Aims and Objectives: To identify the bacteria and fungi causing sepsis in children with acute leukemia and study their antimicrobial profile. Materials and Methods: This descriptive observational study with a cross-sectional study design involved 100 consecutive children admitted to the inpatient department with acute leukemia and clinical sepsis with an acute rise of pediatric sequential organ failure assessment score of more than 2. …”
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Reassessing the relationship between major depressive disorder and blood lipids: a comprehensive Mendelian randomisation study by Lin He, Zhiqiang Li, Jianhua Chen, Chengwen Gao, Yongyong Shi, Yifeng Xu, Qian Zhang, James B Potash, Genmin Sun, Disong Xia, Baiqiang Xue, Xuemin Jian, Lixia Peng, Baokun Wang, Chuanhong Wu, Xiangzhong Zhao, Hui Cao, Yanqin Wen

“…However, the causal dynamics between MDD and dyslipidaemia remain elusive.Aims To comprehensively disentangle the genetic causality between MDD and various phenotypes of blood lipids, thereby facilitating the advancement of management strategies for these conditions.Methods We conducted a two-sample univariable Mendelian randomisation (MR) analysis using different models, including the inverse variance weighted (IVW) method and causal analysis using the summary effect (CAUSE) estimates, as well as a multivariable MR analysis. …”
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Protocol for a multicentre, randomised, parallel-control, superiority trial comparing administration of clotting factor concentrates with a standard massive haemorrhage protocol in... by Neil Parry, Andrew Beckett, Jo Carroll, Homer Tien, Jeannie Callum, Andrew Petrosoniak, Damon Scales, Luis Teodoro da Luz, Keyvan Karkouti, Paul T Engels, Hans-Peter Hucke, Deep Grewal, Bruce Schwartz, Henry Peng

“…However, there is a knowledge gap on their use compared with the standard of care, the transfusion of plasma.Methods and analysis The factors in the initial resuscitation of severe trauma 2 trial is a multicentre, randomised, parallel-control, single-blinded, phase IV superiority trial. …”
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A splice donor variant in SLAMF1 is associated with canine atopic dermatitis by Oliver P. Forman, Jamie Freyer, Abigail Kerr, Julia D. Labadie, Michael Denyer, Debbie J. Gow, Janet Alexander, Michelle Daya, Yaindrys Rodriguez Olivera, Cecilia Lozoya, Christian Leutenegger, Christian Savard, Jason T. Huff, Rebecca Chodroff Foran

“…Further analysis of additional genome sequences and RNA samples from the MARS PETCARE BIOBANK confirmed that the SLAMF1 splice variant is a strong potential contributor to an increased risk of atopic dermatitis.DiscussionThe discovery represents the first compelling genetic variant associated with CAD to be validated in more than one breed of dog. …”
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OM‐85, a Bacterial Lysate, Reduces Pulmonary Nodule Malignant Probability: A Retrospective Study by Mengting Sun, Yuqing Ni, Xueling Wu, Hao Tian, Yijun Song, Yinzhou Feng, Yunxin Guo, Yong Zhang, Jun Yin, Charles A. Powell, Chunxue Bai, Yuanlin Song, Dawei Yang

“…This retrospective study investigated the efficacy of OM‐85, a standardized lysate of human respiratory bacteria, in the treatment of high‐risk pulmonary nodules detected by computed tomography (CT) in patients with chronic bronchitis. Methods This study included 72 patients (93 enrolled nodules) who underwent treatment with OM‐85 and a matched control group of 90 patients (111 control nodules). …”
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Fire ant-venom anaphylaxis prevalence in the general population and patients with systemic mastocytosis by Jeremy C. McMurray, Jeremy C. McMurray, Brandon J. Schornack, Brandon J. Schornack, Karla E. Adams, Robert L. McCoy, Amanda K. Marshall, Janet A. Brunader, Irina Maric, Dean D. Metcalfe, Nathan A. Boggs, Nathan A. Boggs

“…The aim was to determine fire ant-venom anaphylaxis prevalence among Tricare beneficiaries and those with systemic mastocytosis.MethodsWe queried the beneficiary immunotherapy prescription database for patients who received immunotherapy with Hymenoptera venom or fire ant whole-body extract and the Tricare beneficiary population health registry database for patients with an ICD−10 code for Hymenoptera venom allergy (HVA). …”
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Surveillance towards preventing paediatric incidence of respiratory syncytial virus attributable respiratory tract infection in primary and secondary/tertiary healthcare settings i... by Adam Finn, David Lewis, James Dodd, Matthew Taylor, Maia Lesosky, Paul Stephen McNamara, Helen Hill, Emma Carter, Kelly Davies, Fred Fyles, Carla Solorzano, Daniela M Ferreira, Gregory Duncan, Lauren McLellan, Mathieu Bangert, Natalya Vassilouthis, Andrea M Collins

“…Such data will contribute to informing public health strategies to prevent RSV-associated infection, including use of preventative medications.Methods and analysis Parents/carers of children &lt;3 years of age with RTI symptoms will consent for a respiratory sample (nasal swab) to be taken. …”
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Assessing Torquetenovirus (TTV) as a Biomarker for Immune Responses to SARS-CoV-2 mRNA Vaccines in People Living with HIV and Healthy Individuals by Claudia Minosse, Pietro Giorgio Spezia, Valentina Mazzotta, Giulia Matusali, Silvia Meschi, Francesca Colavita, Davide Mariotti, Stefania Notari, Alessandra Vergori, Daniele Focosi, Enrico Girardi, Andrea Antinori, Fabrizio Maggi

“…This study aimed to evaluate whether pre-vaccine TTV VL could predict humoral and cellular immune responses to SARS-CoV-2 mRNA vaccines in people living with HIV (PLWH) and healthy individuals (HP). <b>Methods</b>: TTV VL was measured via real-time PCR in serum samples collected before the second and third doses of mRNA vaccines in 93 PLWH and 48 HP (second dose) and 255 PLWH and 48 HP (third dose). …”
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The Synergistic Effect of Intradialytic Concurrent Training and Melatonin Supplementation on Oxidative Stress and Inflammation in Hemodialysis Patients: A Double-Blind Randomized C... by Houssem Marzougui, Imen Ben Dhia, Ines Mezghani, Rami Maaloul, Salma Toumi, Khawla Kammoun, Mohamed Nejib Chaabouni, Fatma Ayadi, Mohamed Ben Hmida, Mouna Turki, Omar Hammouda

“…Background: This study aimed to investigate the effects of intradialytic concurrent (resistance–endurance) training combined with melatonin (MEL) supplementation on oxidative stress, inflammation, and cellular damage in hemodialysis (HD) patients. Methods: Thirty-two HD patients were randomly assigned to three groups: Exercise (EX)-MEL, EX-Placebo (PLA), and Control (C)-PLA. …”
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Electronic cigarette use in relation to changes in smoking status and respiratory symptoms by Linnéa Hedman<sup>+<sup>, Gustaf Lyytinen<sup>+<sup>, Helena Backman, Magnus Lundbäck, Caroline Stridsman, Anne Lindberg, Hannu Kankaanranta, Lina Rönnebjerg, Eva Rönmark, Linda Ekerljung

“…The aim was to study the association between e-cigarette use and, changes in smoking status and changes in respiratory symptoms. Methods A prospective, population-based study of random samples of the population (age 16–69 years) was performed within The Obstructive Lung Disease in Northern Sweden (OLIN) study and West Sweden Asthma Study (WSAS). …”
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Development and validation of hierarchical signature for precision individualized therapy based on the landscape associated with necroptosis in clear cell renal cell carcinoma by Gao-Sheng Yao, Jun-Shang Dai, Jun-Shang Dai, Liang-Min Fu, Liang-Min Fu, Juan Lin, Zhi-Ping Tan, Lei Dai, Wei Chen, Jun-Hang Luo, Jun-Hang Luo, Jin-Huan Wei

“…Here, we systematically evaluate the role of necroptosis in clear cell renal cell carcinoma (ccRCC) and analyze its regulatory patterns.MethodsFirst, we evaluated the expression and enrichment of necroptotic factors in ccRCC using gene set enrichment analysis (GSEA) and survival analysis in the expression profile from The Cancer Genome Atlas (TCGA) to demonstrate the overall mutation of necroptotic pathway genes. …”
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Integrative genomic and single-cell framework identifies druggable targets for colorectal cancer precision therapy by Yanggang Hong, Yanggang Hong, Jiajun Li, Jiajun Li, Nuo Xu, Wanyi Shu, Feng Chen, Yuze Mi, Haigang Geng, Haigang Geng, Qian Li

“…Despite therapeutic advances, there is a critical need to identify novel, effective, and safe drug targets to improve precision treatment strategies.MethodsWe developed a multi-layered framework integrating Mendelian randomization (MR), colocalization analysis, genome-wide association study (GWAS) data, and expression quantitative trait loci (eQTLs) to prioritize causal and druggable genes in CRC. …”
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Integrating TSPO-PET imaging with metabolomics for enhanced prognostic accuracy in multiple sclerosis by Jens Kuhle, Laura Airas, Daniel C Anthony, David Leppert, Eline Willemse, Fay Probert, Johanna Oechtering, Markus Matilainen, Marcus Sucksdorff, Daniel E Radford-Smith, Abi G Yates, Tereza Kacerova, Marjo Nylund, Aleksandra Maleska Maceski

“…This study investigates whether combining TSPO imaging with metabolomics enhances predictive accuracy in a similar setting.Methods Blood samples were collected from 87 MS patients undergoing PET imaging with the TSPO-binding radioligand 11C-PK11195 in Finland. …”
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Association of body mass index and outcomes in surgical and transcatheter aortic valve replacement by Bennet S. Cho, MD, Troy N. Coaston, BS, Amulya Vadlakonda, BS, Sara Sakowitz, MPH, MS, Syed Shaheer Ali, Esteban Aguayo, MD, Peyman Benharash, MD

“…This study assessed the nuanced relationship between BMI and clinical outcomes in a nationally representative cohort undergoing aortic valve replacement. Methods: Adult (≥18 years) admissions for elective SAVR or TAVR from the 2016–2021 National Inpatient Sample were analyzed. …”
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The features of Tat protein of human immunodeficiency virus type 1 (Retroviridae: <i>Lentivirus: Lentivirus humimdef1</i>) non-A6 variants, characteristic for the Russian Federatio... by Anna I. Kuznetsova, Anastasiia A. Antonova, Aleksey V. Lebedev, Ekaterina N. Ozhmegova, Anastasia V. Shlykova, Ilya A. Lapovok, Oxana V. Galzitskaya

“…A limitation of this study is the small sample of sequences.…”
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Exploring the role of ELOVLs family in lung adenocarcinoma based on bioinformatic analysis and experimental validation by Zihan Wang, Wenjing Cui, Long Liang, Jingge Qu, Yuqiang Pei, Danyang Li, Ying Luo, Yue Zhang, Yifan Qiu, Yongchang Sun

“…The aim of our study is to explore whether there are genes related to the pathogenesis of LUAD in the ELOVLs family, and even to guide clinical medication and potential prognostic indicators. Methods Gene expression profiling interactive analysis (GEPIA), human protein atlas (HPA), cBioPortal, Kaplan–Meier (KM) plotter, single-sample Gene Set Enrichment Analysis (ssGSEA) algorithm and SubMap algorithms were utilized to analyze the role of ELOVLs in the LUAD. …”
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Effect of charcoal-containing toothpastes on roughness and color stability of bulk-fill resin composites by Waldemir Francisco Vieira Junior, Rafaella Queiróz Costa, Leonardo Santos Barros, Mariana Mayume Mori, Cecilia Pedroso Turssi, Fabiana Mantovani Gomes França, Núbia Inocencya Pavesi Pini, Roberta Tarkany Basting

“… Objective: To evaluate the effects of different commercially available charcoal-based toothpastes (CBTs) on the roughness and color of bulk-fill resin composites (RCs). Materials and Methods: Disc-shaped samples (6 × 2 mm) were made with nanofilled (NF) bulk-fill (Filtek One, 3M Oral Care) or nanohybrid (NH) bulk-fill (Aura, SDI) RCs. …”
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Construction of mitochondrial signature (MS) for the prognosis of ovarian cancer by Miao Ao, You Wu, Kunyu Wang, Haixia Luo, Wei Mao, Anqi Zhao, Xiaomeng Su, Yan Song, Bin Li

“…This study focuses on exploring the mitochondria-related genes for the prognosis of OV. Methods RNA expression profiles and single-cell data were acquired from The Cancer Genome Atlas (TCGA), International Cancer Genome Consortium (ICGC), and Gene Expression Omnibus databases for screening and validating mitochondria-related differentially expressed genes (DEGs). …”
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