Subtype cluster analysis unveiled the correlation between m6A- and cuproptosis-related lncRNAs and the prognosis, immune microenvironment, and treatment sensitivity of esophageal c... by Ming Zhang, Yani Su, Pengfei Wen, Xiaolong Shao, Peng Yang, Peng An, Wensen Jing, Lin Liu, Zhi Yang, Mingyi Yang

“…This study seeks to elucidate the impact of m6A- and cuproptosis-related long non-coding RNAs (m6aCRLncs) on the prognosis of patients with EC.MethodsThe EC transcriptional data and corresponding clinical information were retrieved from The Cancer Genome Atlas (TCGA) database, comprising 11 normal samples and 159 EC samples. Data on 23 m6A regulators and 25 cuproptosis-related genes were sourced from the latest literature. …”
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A Localized Evaluation of Surface Water Quality Using GIS-Based Water Quality Index along Satpara Watershed Skardu Baltistan, Pakistan by Ali Muhammad, Donghui Shangguan, Ghulam Rasool, Amjad Ali Khan, Asim Qayyum Butt, Ayesha Hussain, Muhammad Ahsan Mukhtar

“…A total of fifty-one surface water samples were collected from various parts of the Satpara watershed during the fall season of 2023. …”
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ChatGPT4’s diagnostic accuracy in inpatient neurology: A retrospective cohort study by Sebastian Cano-Besquet, Tyler Rice-Canetto, Hadi Abou-El-Hassan, Simon Alarcon, Jason Zimmerman, Leo Issagholian, Nasser Salomon, Ivan Rojas, Joseph Dhahbi, Michael M. Neeki

“…Further studies with larger sample sizes and independent third-party evaluations are recommended to confirm these findings and assess the impact of LLMs on patient health.…”
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Developing a European Psychotherapy Consortium (EPoC): Towards Adopting a Single-Item Self-Report Outcome Measure Across European Countries by Miguel M. Gonçalves, Wolfgang Lutz, Brian Schwartz, João Tiago Oliveira, Suoma E. Saarni, Orya Tishby, Julian A. Rubel, Jan R. Boehnke, Adrian Montesano, Dario Paiva, Davide Ceridono, Emmanuelle Zech, Jochem Willemsen, Samuli I. Saarni, Katarina Kompan Erzar, Luís Janeiro, Omar C. G. Gelo, Paula Errázuriz, Pawel Holas, Rafał Styła, Tatjana Rožič, Tom Rosenström, Vera Békés, Zsolt Unoka, Michael Barkham

“…[Background] Complementing the development of evidence-based psychological therapies, practice-based evidence has developed from patient samples collected in routine care, addressing questions relevant to patients and practitioners, and thereby expanding our knowledge of psychological therapies and their impact. …”
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Higher education students' perceptions of ChatGPT: A global study of early reactions. by Dejan Ravšelj, Damijana Keržič, Nina Tomaževič, Lan Umek, Nejc Brezovar, Noorminshah A Iahad, Ali Abdulla Abdulla, Anait Akopyan, Magdalena Waleska Aldana Segura, Jehan AlHumaid, Mohamed Farouk Allam, Maria Alló, Raphael Papa Kweku Andoh, Octavian Andronic, Yarhands Dissou Arthur, Fatih Aydın, Amira Badran, Roxana Balbontín-Alvarado, Helmi Ben Saad, Andrea Bencsik, Isaac Benning, Adrian Besimi, Denilson da Silva Bezerra, Chiara Buizza, Roberto Burro, Anthony Bwalya, Cristina Cachero, Patricia Castillo-Briceno, Harold Castro, Ching Sing Chai, Constadina Charalambous, Thomas K F Chiu, Otilia Clipa, Ruggero Colombari, Luis José H Corral Escobedo, Elísio Costa, Radu George Crețulescu, Marta Crispino, Nicola Cucari, Fergus Dalton, Meva Demir Kaya, Ivo Dumić-Čule, Diena Dwidienawati, Ryan Ebardo, Daniel Lawer Egbenya, MoezAlIslam Ezzat Faris, Miroslav Fečko, Paulo Ferrinho, Adrian Florea, Chun Yuen Fong, Zoë Francis, Alberto Ghilardi, Belinka González-Fernández, Daniela Hau, Md Shamim Hossain, Theo Hug, Fany Inasius, Maryam Jaffar Ismail, Hatidža Jahić, Morrison Omokiniovo Jessa, Marika Kapanadze, Sujita Kumar Kar, Elham Talib Kateeb, Feridun Kaya, Hanaa Ouda Khadri, Masao Kikuchi, Vitaliy Mykolayovych Kobets, Katerina Metodieva Kostova, Evita Krasmane, Jesus Lau, Wai Him Crystal Law, Florin Lazăr, Lejla Lazović-Pita, Vivian Wing Yan Lee, Jingtai Li, Diego Vinicio López-Aguilar, Adrian Luca, Ruth Garcia Luciano, Juan D Machin-Mastromatteo, Marwa Madi, Alexandre Lourenço Manguele, Rubén Francisco Manrique, Thumah Mapulanga, Frederic Marimon, Galia Ilieva Marinova, Marta Mas-Machuca, Oliva Mejía-Rodríguez, Maria Meletiou-Mavrotheris, Silvia Mariela Méndez-Prado, José Manuel Meza-Cano, Evija Mirķe, Alpana Mishra, Ondrej Mital, Cristina Mollica, Daniel Ionel Morariu, Natalia Mospan, Angel Mukuka, Silvana Guadalupe Navarro Jiménez, Irena Nikaj, Maria Mihaylova Nisheva, Efi Nisiforou, Joseph Njiku, Singhanat Nomnian, Lulzime Nuredini-Mehmedi, Ernest Nyamekye, Alka Obadić, Abdelmohsen Hamed Okela, Dorit Olenik-Shemesh, Izabela Ostoj, Kevin Javier Peralta-Rizzo, Almir Peštek, Amila Pilav-Velić, Dilma Rosanda Miranda Pires, Eyal Rabin, Daniela Raccanello, Agustine Ramie, Md Mamun Ur Rashid, Robert A P Reuter, Valentina Reyes, Ana Sofia Rodrigues, Paul Rodway, Silvia Ručinská, Shorena Sadzaglishvili, Ashraf Atta M S Salem, Gordana Savić, Astrid Schepman, Samia Mokhtar Shahpo, Abdelmajid Snouber, Emma Soler, Bengi Sonyel, Eliza Stefanova, Anna Stone, Artur Strzelecki, Tetsuji Tanaka, Carolina Tapia Cortes, Andrea Teira-Fachado, Henri Tilga, Jelena Titko, Maryna Tolmach, Dedi Turmudi, Laura Varela-Candamio, Ioanna Vekiri, Giada Vicentini, Erisher Woyo, Özlem Yorulmaz, Said A S Yunus, Ana-Maria Zamfir, Munyaradzi Zhou, Aleksander Aristovnik

“…The paper presents the most comprehensive and large-scale global study to date on how higher education students perceived the use of ChatGPT in early 2024. With a sample of 23,218 students from 109 countries and territories, the study reveals that students primarily used ChatGPT for brainstorming, summarizing texts, and finding research articles, with a few using it for professional and creative writing. …”
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How public health teams navigate their different roles in alcohol premises licensing: ExILEnS multistakeholder interview findings by Rachel O’Donnell, Andrea Mohan, Richard Purves, Nason Maani, Matt Egan, Niamh Fitzgerald

“…Conclusions In engaging with alcohol licensing, public health stakeholders adapted their approaches, sometimes resulting in a diminished focus on public health goals. Sampling did not include lower-activity areas, in which experiences might differ. …”
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Precision computerised cognitive behavioural therapy (cCBT) intervention for adolescents with depression (SPARX-UK): protocol for the process evaluation of a pilot randomised contr... by Charlotte Lucy Hall, Chris Hollis, Kareem Khan, Peter Fonagy, Kirsty Sprange, Cathy Creswell, Yi Yang, Vibhore Prasad, Kapil Sayal, Nitish Jawahar, Ellen Townsend, Dorothee Auer, Praveetha Patalay, Aja Murray, Yvonne Kelly, Boliang Guo, Christopher R Tench, Paul Stallard, Louise Arseneault, Sieun Lee, Sally Merry, Charlotte Hall, Jo Gregory, Rory O’Connor, Emma Nielsen, Edmund Sonuga-Barke, Hannah Wright, Petr Slovak, Emily Lloyd, Josimar De Alcantara Mendes, Carolyn Ten Holter, Marina Jirotka, Aaron Kandola, Sonia Livingstone, Kasia Kostryka-Allchorne, Jake Bourgaize, Mariya Stoilova, Marianne Etherson, Chris Greenhalgh, Jim Warren, Vajisha Wanniarachchi, Kevin Glover, Mathijs Lucassen, Karolina Stasiak, Camilla Babbage, Adam Parker, Joanna Lockwood, Elvira Perez Vallejos, Rebecca Woodcock, Sarah Doherty, Lucy-Paige Willingham, Camilla May Babbage, Matthew Jeffery, Peiyao Tang, Holly Griffiths, Lily Roberts, A. Jess Williams, Lucy Hitcham

“…The findings from this process evaluation will also inform the decision about whether and how to proceed with a full randomised controlled trial, as well as the development of more effective interventions which can be personalised more precisely via varying levels of human support. …”
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MRD4U: A path to development for personalized liquid biopsy for children with central nervous system tumors by Anthony R. Miller, Tithi Shah, Corinne N. Strawser, Adithe Rivaldi, Sarah A. Wilson, Huachun Zhong, Jocelyn M. Lucyshyn, Elizabeth AR Garfinkle, Makenna McCoy, Seth Cummins, Alejandro Otero Bravo, Peter Chang, Gregory L. Wheeler, David M. Gordon, Benjamin J. Kelly, Caitlyn Evanovich, Samara L. Potter, Elizabeth A. Varga, Diana P. Rodriguez, Richard K. Wilson, Catherine E. Cottrell, Ralph Salloum, Sara Khan, Maryam Fouladi, Elaine R. Mardis, Margot A. Lazow, Katherine E. Miller

“…Ultimately, this strategy may inform clinical decision-making and enable earlier therapeutic intervention.…”
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Rapid, sensitive, and species-independent detection of Crimean Congo hemorrhagic fever virus nucleoprotein and GP38 antibodiesResearch in context by Elif Karaaslan, Cheng-Feng Chiang, Gülter Öncü Kurutaş, Orçun Barkay, Nesibe Selma Çetin Güler, Merve Yazıcı Kalkan, Hanife Nur Karakoç Parlayan, Özlem Akdoğan, Aysel Kocagül Çelikbaş, Firdevs Aksoy, Umut Devrim Binay, Nurcan Baykam, Gürdal Yılmaz, Mohammad M. Sajadi, Scott D. Pegan, John D. Klena, Joel M. Montgomery, Faruk Karakeçili, Ahmet Kalkan, Mehmet Ziya Doymaz, Christina F. Spiropoulou, Éric Bergeron

“…National Institute of Allergy and Infectious Diseases (1R01AI180125-01A1): sample acquisition. Funding sources did not have a role in the writing or decision to submit the publication.…”
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Integrating Gut Microbiome and Metabolomics with Magnetic Resonance Enterography to Advance Bowel Damage Prediction in Crohn’s Disease by Huang L, Meng J, Lin S, Peng Z, Zhang R, Shen X, Zheng W, Zheng Q, Wu L, Wang X, Wang Y, Mao R, Sun C, Li X, Feng ST

“…This allowed us to observe signs of inflammation, such as thickened bowel walls, swelling in the surrounding tissues, abnormal blood vessel patterns, as well as other structural damage.Gut Bacteria Analysis: We examined stool samples to understand the variety and balance of the gut bacteria.Metabolite Testing: We analyzed both stool and blood samples to measure metabolic markers.We studied 309 individuals with Crohn’s disease and compared them with 30 healthy volunteers. …”
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Clinical trial and real-world evidence of circulating tumor DNA monitoring to predict recurrence in patients with resected colorectal cancer by H.T. Nguyen, V.-A. Nguyen Hoang, T.V. Nguyen, N.A.L. Trinh, T.H. Pham, D.N. Le, H.H. Ho, T.D. Nguyen, H.D. Nguyen, T.S.L. Thi, N. Nguyen, D.H. Tran, M.T. Le, T.C. Dinh, T.S. Nguyen, K.C.N. The, H. Mai, M.T. Chu, D.H. Pham, N.H.T. Phuc, D.N. Vinh, D.-N. Nguyen, X.-V. Nguyen, D.S. Nguyen, T.T.D. Thi, H. Giang, H.-N. Nguyen, L.N. Tu

“…Materials and methods: In our prospective clinical trial, 92 patients with stage I-IVA CRC and eligible for curative-intent surgery were recruited. Blood samples were collected before surgery, after surgery and during surveillance. ctDNA analysis was carried out using a personalized tumor-informed approach. …”
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Serum proteomics of adults with acute liver failure provides mechanistic insights and attractive prognostic biomarkers by Katharina Remih, Franziska-Maria Hufnagel, Anna Sophie Karl, Valerie Durkalski-Mauldin, William Martens Lee, Constantine J. Karvellas, Zemin Su, Jody A. Rule, Petra Tomanová, Laura Krieg, Isabel Karkossa, Kristin Schubert, Martin von Bergen, Frank Tacke, Sonja Luckhardt, Nicole Ziegler, Aimo Kannt, Bastian Engel, Richard Taubert, Robert John Fontana, Pavel Strnad

“…More sensitive and specific prognostic scores are urgently needed to facilitate decision-making regarding liver transplantation in patients with ALF. …”
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Effects of previous steroid treatment on ischemic stroke outcomes: a propensity score-matched hospital analysis by Yasser Alatawi, Eman A. Alraddadi, Eman A. Alraddadi, Abdullah A. Alhifany, Faisal E. Alzahrani, Faisal E. Alzahrani, Saud M. Alknawy, Saud M. Alknawy, Nawaf M. Aljohani, Nawaf M. Aljohani, Husun K. Kecheck, Husun K. Kecheck, Alanoud K. Alaslab, Alanoud K. Alaslab, Aser F. Alamri, Aser F. Alamri, Ahmed Aljabri, Daniyah A. Almarghalani, Daniyah A. Almarghalani, Faisal F. Alamri, Faisal F. Alamri

“…Future studies with larger sample sizes and more detailed data on steroid use and stroke outcomes are required. …”
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Interventions that challenge established and accepted clinical practice: lessons learnt from a process evaluation of the STOP-APE trial by Agnieszka Ignatowicz, Sheila Greenfield, Pooja Gaddu, Clare Prince, Mark Toshner, Graham Robinson, Jonathan Rodrigues, Susan Jowett, Simon Noble, Michael Newnham, Alice Turner, Daniel Lasserson

“…These complexities are deeply intertwined, influencing both clinical decision-making and patient recruitment for those studies. …”
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Julius Kruopis – the pioneer of applied statistics in Lithuania by Vilijandas Bagdonavičius, Vydas Čekanavičius, Rūta Levulienė, Pranas Vaitkus

“…For example, the problem of making an optimal decision when choosing a distribution from several possible alternative distributions was examined. …”
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Understanding patient pathways to Mother and Baby Units: a longitudinal retrospective service evaluation in the UK by Nikolina Jovanović, Žan Lep, Giles Berrisford, Aysegul Dirik, Julia Barber, Bukola Kelani, Olivia Protti

“…More research is needed to determine whether this is due to clinical decisions or gaps in the care system.…”
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Effectiveness of biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: the BATCH RCT by Cherry-Ann Waldron, Philip Pallmann, Simon Schoenbuchner, Debbie Harris, Lucy Brookes-Howell, Céu Mateus, Jolanta Bernatoniene, Katrina Cathie, Saul N Faust, Josie Henley, Lucy Hinds, Kerry Hood, Chao Huang, Sarah Jones, Sarah Kotecha, Sarah Milosevic, Helen Nabwera, Sanjay Patel, Stéphane Paulus, Colin VE Powell, Jenny Preston, Huasheng Xiang, Emma Thomas-Jones, Enitan D Carrol

“…Incremental cost-effectiveness ratio per duration of intravenous antibiotics hour avoided from bootstrapped samples was £467.62 per intravenous antibiotic hour avoided. …”
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Assessing the Role of Mining in Ghorveh County on the Sustainability of Surrounding Villages by Akram Nasiri, Jafar Tavakkoli

“…Then utilizing a questionnaire, Field data was collected. The sample size included 330 householders of investigated villages that were studied in two groups of working and non-working in the mine. …”
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Interpretive structural modeling of the implementation of the comprehensive scientific map of Iran by Bahram Akbari, Abouzar Alidadi Talkhestani, Mohammad Reza Navab Esfahani, Meysam Alipour

“…The statistical population of the research includes experts and officials implementing the country's scientific map, from which a sample size of 20 people was purposefully selected, and their opinions were used in responding to the structural-interpretive equations.Findings: The final model has been developed in two layers and consists of 5 dimensions, including "human factors," "infrastructural factors," "management factors," "process factors," and "external factors." …”
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International Migration and Its Consequences Affecting Population Management in Isfahan Province: A Grounded Theory Study by Mohammad Hosain Ghanbari Jahromi, Javad Esteki, Hamid Nazari

“…Data were collected through semi-structured individual interviews, employing purposeful sampling. This method allowed for in-depth exploration of participants' experiences and perspectives regarding migration to Isfahan. …”
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