Efficacy of Air and Oxygen Micro-nano Bubble Waters Against Colletotrichum gloeosporioides and Impacts on Postharvest Quality of ‘Fan Retief’ Guava Fruit by Harold K. Malahlela, Zinash A. Belay, Rebogile R. Mphahlele, Oluwafemi James Caleb

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Molecular and immunological features associated with long-term benefits in metastatic NSCLC patients undergoing immune checkpoint blockade by Pedro Rocha, Rafael Bach, Laura Masfarré, Sharia Hernandez, Nil Navarro-Gorro, Adrià Rossell, Xavier Villanueva, Mario Giner, Ignacio Sanchéz, Miguel Galindo, Raúl Del Rey-Vergara, Albert Iñañez, Beatriz Sanchéz-Espiridion, Wei Lu, Ariadna Acedo-Terrades, Pau Berenguer-Molins, Albert Sánchez-Font, Roberto Chalela, Victor Curull, Álvaro Taus, Max Hardy-Werbin, Mark Sausen, Andrew Georgiadis, James White, Jennifer B Jackson, Laura Moliner, Sergi Clavé, Beatriz Bellosillo, Ana Rovira, Ignacio Wistuba, Luisa M Solis Soto, Júlia Perera-Bel, Edurne Arriola

“…At a baseline, LTR patients exhibited higher serum levels of proteins related with apoptosis (CASP8, PRKRA), chemotaxis, immune proteasome, processing of MHC class I (S100A4, PSMD9, RNF41) and immune homeostasis (HAVCR1, ARG1) (p < 0.05). …”
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<i>Microchloropsis gaditana</i> as a Natural Antimicrobial with a One Health Approach to Food Safety in Farmed Salmon by Nelson Díaz, Susana Muñoz, Alberto Medina, Carlos Riquelme, Ivonne Lozano-Muñoz

“…A spray-dried <i>M. gaditana</i> concentrate (Mg) was elaborated and given to Atlantic salmon for a period of 49 days, and serum and fillet samples were collected. Our results showed a significant increase in the nutritional quality improving the levels of EPA+ Docosapentaenoic acid (DPA) (23%) and Vitamin D₃ (106%) of the fillets treated with Mg. …”
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Molecular and immune landscape of tumours in geriatric patients with non-small cell lung cancer, melanoma and renal cell carcinoma by Abdul Rafeh Naqash, April K Salama, Emil Lou, Andrew Elliott, Wafik S El-Deiry, Chul Kim, Stephen V Liu, Anwaar Saeed, Hirva Mamdani, Khalil Choucair, Dipesh Uprety, Phillip Walker, Himisha Beltran, Matthew James Oberley, Azhar Saeed, Lujia Chen

“…Then, using next-generation sequencing and programmed death-ligand 1 (PD-L1) assessment, we evaluated gene expression differences between age groups and across tumour types, with a focus on ageing-related processes such as DNA damage response (DDR), immune checkpoint (IC) and metabolism-related genes. …”
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The physicochemical and microbiological quality of meat produced in a traditional slaughterhouse in Mansoura City, Egypt by Mahmoud Ahmed Mahros, Hend Ali Elshebrawy, Samir Mohammed Abd-Elghany, Mohammed Mohammed Elgazzar, Kálmán Imre, Adriana Morar, Viorel Herman, Khalid Ibrahim Sallam

“…In the Mansoura slaughterhouse, animals are subjected to various stressors and treated with cruelty, in addition to unhygienic treatment and handling of animal carcasses. …”
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Wind Power Forecasting Based on Multi-Graph Neural Networks Considering External Disturbances by Xiaoyin Xu, Zhumei Luo, Menglong Feng

“…Meanwhile, real-time performance analysis confirms the model’s operational viability as it maintains excellent prediction accuracy (RMSE < 15) even at high data arrival rates (100 samples/second) while ensuring processing latency below critical thresholds (10 ms) under typical system loads.…”
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Antimicrobial resistance transmission in the environmental settings through traditional and UV-enabled advanced wastewater treatment plants: a metagenomic insight by Absar Talat, Yasir Bashir, Nadeem Khalil, Connor L. Brown, Dinesh Gupta, Asad Ullah Khan

“…Results The dominance of Proteobacteria or Pseudomonadota, characterized the samples from both WWTPs and carried most ARGs. Acinetobacter johnsonii, a prevailing species, exhibited a diminishing trend with wastewater treatment, yet its persistence and association with antibiotic resistance underscore its adaptive resilience. …”
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Research on the expression of E-cadherin in lung cancer tumors with different histological structures by E. N. Kolesnikov, O. N. Stateshny, D. A. Kharagezov, E. A. Mirzoyan, T. G. Ayrapetova, A. G. Milakin, K. D. Iozefi

“…The obtained data have been processed using the Statistica 13.0 program (StatSoftInc., USA). …”
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Potential immunomodulatory effects of the extract from Artemisia frigida Willd on loaches infested with Aeromonas hydrophila revealed by microRNA analysis by Yue Zhao, Yue Zhao, Yue Zhao, Yuqing Qiu, Lishang Dai, Hong Wang

“…Bioinformatics analysis identified 924 and 923 conserved miRNAs in control and AF (Artemisia frigida) treated samples, respectively, and 30 (26 upregulated and 4 downregulated) differentially expressed miRNAs were screened. …”
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On the performance of electrocoagulation treatment of high-loaded gray water: kinetic modeling and parameters optimization via response surface methodology by Khalid Bani-Melhem, Mohammad Alnaief, Zakaria Al-Qodah, Mohammad Al-Shannag, Haitham Elnakar, Nawzat AlJbour, Muhammad Alu’datt, Mohammad Alrosan, Ezelden Ezelden

“…Moreover, the research examines the kinetics involved in the removal of COD, color, and turbidity from HLGW. Various HLGW samples were treated at different current densities over a 90-min EC period. …”
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Institutional, neighborhood, and life stressors on loneliness among older adults by Kazumi Tsuchiya, Amy Danielle Thierry, Harry Owen Taylor

“…Future research and interventions should consider the differing stress appraisal processes across groups and to support the development of resources and policies to ameliorate loneliness among diverse older adults.…”
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Impact of contract farming on householders' income, intensification, and land productivity in Ethiopia: evidence from smallholder malt barley producers in the highlands of the Cent... by Tamrat Gebiso Challa, Ephrem Boka Dube, Ibsa Dawid, Eihab Fathelrahman

“…IntroductionContract farming (CF) is an agreement between farmers and processing and/or marketing firms for the production and supply of agricultural products under forward agreements, frequently at predetermined prices. …”
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Vancomycin-resistant enterococci and coagulase-negative staphylococci prevalence among patients attending at Felege Hiwot Comprehensive Specialized Hospital, Bahir Dar, Ethiopia. by Degu Ashagrie, Chalachew Genet, Bayeh Abera

“…Simultaneously urine, venous blood and wound swab were collected and processed following standard bacteriological technique. …”
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The role of glutathione S-transferase mu 2 in mitigating fatty acid–induced hepatic inflammation in dairy cows by Jinxia Li, Chenchen Zhao, Dandan Qi, Fanrong Kong, Menglin Liu, Jie Gao, Enzhu Li, Wenwen Gao, Xiliang Du, Yuxiang Song, Xinwei Li, Haihua Feng, Lin Lei

“…Targeting GSTM2 may offer new strategies to treat or prevent fatty liver disease in dairy cows.…”
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The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy by Stefaniya K. Boneva, Julian Wolf, Malte Jung, Gabriele Prinz, Toco Y. P. Chui, Jacqueline Jauch, Anne Drougard, J. Andrew Pospisilik, Anja Schlecht, Felicitas Bucher, Richard B. Rosen, Hansjürgen Agostini, Günther Schlunck, Clemens A. K. Lange

“…Conclusion Our results strongly indicate a critical role for vitreous hyalocytes in key pathophysiological processes of proliferative diabetic retinopathy: inflammation, angiomodulation and erythrophagocytosis. …”
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Hypoxic mesenchymal stem cell-derived exosomal circDennd2a regulates granulosa cell glycolysis by interacting with LDHA by Wenxin Li, Minjun Lu, Junyu Shang, Jiamin Zhou, Li Lin, Yueqin Liu, Dan Zhao, Xiaolan Zhu

“…Results Our findings revealed depletion of circDennd2a in serum samples and GCs from individuals suffering from POI. …”
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LncRNA-mRNA co-expression network in the mechanism of butylphthalide treatment for ischemic stroke by Yangfang An, Lingyun Huang, Jun Li, Zhuo Chen, Jizhang Cai, Biao Wang, Qiong Zhou

“…Methods Peripheral blood samples were collected from ischemic stroke patients treated with butylphthalide and from control subjects. mRNA and lncRNA expression profiles were obtained using microarray scanning, and differentially expressed lncRNAs (DElncRNAs) were validated by qRT-PCR. …”
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Comparative Evaluation of Susceptibility Results from the Liofilchem Antifungal Multodiscs and the VITEK® 2 Susceptibility Tests for Candida Species Causing Bloodstream Infections... by Mrs Rochelle Charvis, Dr Glendee Reynolds Campbell, Dr Neil McKnight, Mrs. Alrica Bruce-Mowatt

“…Results: Candida species were isolated from 38 of the 7853 blood culture samples processed during the period (0.5% prevalence). …”
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Polineoplasia in patients with cervical cancer in the Chelyabinsk region of Russia by S. A. Bekhtereva, A. S. Domogirova, A. V. Vazhenin, I. A. Aksenova

“…Using the method of continuous sampling, we carried out a retrospective analysis of the case histories of patients with PMC of the female reproductive system treated in the SBEO CRCOD for 15 years (1999-2013).Results. …”
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Urine proteomics defines an immune checkpoint-associated nephritis signature by Cassian Yee, Jamie S Lin, James P Long, Shailbala Singh, Yanlan Dong

“…Thus, there is an urgent need for non-invasive biomarkers that can rapidly and accurately distinguish ICI-AIN from other causes of AKI.The urine and plasma proteome contain actively secreted proteins that provide real-time insights into dynamic physiological processes. However, identification of effective biomarkers of disease using established technologies such as proximity ligation assays (PLA) and bead-based immunoassays is challenging due to their limited sensitivity and loss of precision in multiplex analysis.To address this, we employed cutting-edge NUcleic acid Linked Immuno-Sandwich Assay (NULISA) technology to measure protein expression in urine and plasma samples from AKI patients undergoing ICI therapy. …”
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