Screening for primary aldosteronism in 1,181 Swedish primary care patients with hypertension by Nikita Makhnov, Nikita Makhnov, Nikita Makhnov, Jakob Skov, Jakob Skov, Tobias Åkerström, Tobias Åkerström, Fredrik Axling, Daniel Andernord, Mikael Bergenheim, Mikael Bergenheim, Mauritz Waldén, Per Hellman, Per Hellman

“…Plasma aldosterone and ARR were compared under different stages of the diagnostic process. All patients with PA were offered adrenal venous sampling, or, in certain cases, adrenocortical-specific positron emission tomography. …”
Get full text

Tumor and peritumoral tissue hormonal background features in patients with rare types of endometrial cancer by E. M. Frantsiyants, V. A. Bandovkina, A. P. Menshenina, T. I. Moiseenko, M. A. Rogozin, Yu. A. Pogorelova, I. V. Kaplieva, E. I. Surikova, I. V. Neskubina, N. D. Cheryarina, E. V. Verenikina

“…The local levels of estrogens and androgens were determined in the tumor tissue, the perifocal zone, endometrial tissue unaffected by the tumor process, and the fallopian tube tissue in patients with SEIC and CCEC. …”
Get full text

Enhanced Proximal Caries Remineralization Using Cav-Aid^®, a Novel Fluoride Delivery Device: An In Vitro Study by Chase David Hardy, Bennett Tochukwu Amaechi, Kannan Kanthaiah, Amos Chinedu Obiefuna, Mahalakshmi Vijayaraghavan, Nahid Iftikhar, Kyumin Whang, Maria-Jose Cervantes Mendez, Stanislaus Dyda

“…Methods: Initial caries lesions were produced on bovine enamel blocks by subjecting the blocks to a 3-day demineralization process by plaque growth in a mixed-species microbial caries model. …”
Get full text

Combined effect of chitosan and gamma ray on quality of chilled fresh pork by WANG Jingjing, XU Chao, YANG Tilong, LIU Xunyue, DING Xingcheng

“…However, the major problem associated with chilled pork is its susceptibility to contamination by pathogenic bacteria in the process of slaughtering, processing and transportation. …”
Get full text

The lncRNA LOC100257036 and vvimiR156 modulate gibberellin signaling through AGAMOUS during cluster formation in Sistan Yaghooti grape by Shahla Sahraei, Nafiseh Mahdinezhad, Abbasali Emamjomeh, Kaveh Kavousi, Mahmood Solouki, Massimo Delledonne

“…Furthermore, pathway analysis indicated that majority of genes in the treated samples were primarily linked to metabolic pathways and secondary metabolite biosynthesis in comparison to the control group. …”
Get full text

Cobalt Chloride-simulated Hypoxia Promoted Ossification of the Posterior Longitudinal Ligament Through the HIF1A–BMP4 Axis by Shihao Lu, Junbin Liu, Junzhe Sheng, Aochen Xu, Zichuan Wu, Chen Xu, Jiabin Yuan, Yang Liu

“…This study reports the potential involvement of HIF1A in the development of OPLL and investigates the regulatory role of the HIF1A-BMP4 axis in this process.…”
Get full text

Providing a General Model for the Successful Implementation of Digital Transformation in Organizations by Haidar Ahmadi, Najme Parsaei, Seyyed Hamed Hashemi, Hamidreza Nematollahi

“…The participants of this research are professors and specialists in the fields of digital transformation and management, carefully selected through purposeful sampling to ensure they meet specific criteria that qualify them to provide insightful information. …”
Get full text

Microstructure and corrosion properties of 625 Ni-based alloy surfacing layer on the inner-wall of oil pipe prepared by twin tungsten electrode TIG welding with heat wire by Juan PU, Sutong SHI, Hongbing WEI, Mingfang WU, Huawei SUN, Weimin LONG

“…Two Inconel 625 Ni-based alloy surfacing layers were prepared on the inner wall of high-strength steel in oil pipeline by using double tungsten electrode TIG technology with hot wire that was controlled by independent power supply. The samples obtained from the oil pipeline were solution treated at the temperature of 800 ℃ and 900 ℃, respectively. …”
Get full text

Microalgae-based treatment of produced water: A comparison between synthetic and a representative real produced water by Hussain Ali Al Subaie, Nur Farahah Khairuddin, Muhammad Nawaz Tahir, Muslim Aqeel Alhaddad, Mohammed Omar Faruque, Shaikh Abdur Razzak, Basheer Chanbasha, Ahsan Mushir Shamsi, Muhammad Shahzad Kamal, Wasif Farooq

Get full text

Assessing the impact of resistance training on renal function of female wistar rats under cross-sex hormone therapy by Isadora Gonçalves Almeida, Isabela Borges M. Silveira, Isabela Borges M. Silveira, Emily Rocha Cordeiro, Letícia Maria Monteiro, Letícia Maria Monteiro, Nathalia Beserra da Silva, Nathalia Beserra da Silva, Rogerio Argeri, Rogerio Argeri, Debora C. K. Lichtenecker, Magnus R. Dias da Silva, Magnus R. Dias da Silva, Guiomar Nascimento Gomes

“…At the end of the protocol, the animals were placed in metabolic cages for urine collection, followed by blood sampling for biochemical analysis.ResultsTestosterone-treated groups showed increased plasma creatinine levels, though urea concentrations were unchanged. …”
Get full text

Balancing Innovation and Ethics by Anisa Patel

“…After the lab receives the sample, scientists use DNA sequencing, the process of determining the sequence of nucleotides, to map out the genetics of a person. …”
Get full text

Balancing Innovation and Ethics by Anisa Patel

“…After the lab receives the sample, scientists use DNA sequencing, the process of determining the sequence of nucleotides, to map out the genetics of a person. …”
Get full text

Difference analysis in the content of the total phenols, flavonoid, and anthocyanin of 149 accessions of hawthorn gremplasm resources by ZHAO Baipeng, CUI Mingqi, SUN Xinyu, WANG Yu, WANG Xiangxu, LIU Yuexue, ZHANG Xiao

“…After the extraction process, the samples were centrifuged at 12 000 r·min-1 for 10 minutes at 4 ℃ to separate the supernatant from the solid residue. …”
Get full text

Effects of combined soluble gas stabilization, modified atmosphere packaging and cold plasma on controlling chilled chicken breasts spoilage by Jing Li, Chen Xu, Yifeng Lu, Xiaoming Wang, Shuangshuang Jin, Yun Bai, Xia Wang, Xinglian Xu, Minyi Han

“…Simultaneously, the effect of SGS, MAP, and CP combinational treatments significantly extended the storage time of chilled chicken breasts while maintaining the physicochemical qualities of samples. Compared to the control group, the TVC of chicken breast treated with SGS, MAP, and CP treatments decreased by 0.58 (lg(CFU/g)) at 0 day. …”
Get full text

Investigating the mechanism of inositol against paclitaxel chemoresistance on triple-negative breast cancer by using 7T multiparametric MRI and mitochondrial changes by Wentao Xuan, Wangmin Li, Lixin Ke, Yuanyu Shen, Xiaolei Zhang, Yue Chen, Zhiliang Ye, Caiyu Zhuang, Shiyan Xie, Renhua Wu, Yan Lin

“…Inositol’s inhibition of this process makes it a potential therapy. Multiparametric MRI provides an early and effective assessment of these innovations. …”
Get full text

Fusobacterium mortiferum and its metabolite 5-aminovaleric acid promote the development of colorectal cancer in obese individuals through Wnt/β-catenin pathway by DKK2 by Jiaxin Deng, Jiawei Zhang, Mingli Su, Juan Li, Yuping Su, Qinghua Zhong, Jiancong Hu, Yongcheng Chen, Sen Liao, Dezheng Lin, Xuefeng Guo

“…Additional mechanistic studies revealed that 5-AVA interacts with the demethylase KDM6B, affecting the demethylation process of DKK2 and subsequently activating the Wnt/β-catenin signaling pathway. …”
Get full text

Bioactive Sphingolipids, Complement Cascade, and Free Hemoglobin Levels in Stable Coronary Artery Disease and Acute Myocardial Infarction by T. Jadczyk, K. Baranski, M. Syzdol, E. Nabialek, W. Wanha, R. Kurzelowski, M. Z. Ratajczak, M. Kucia, B. Dolegowska, M. Niewczas, J. Zejda, W. Wojakowski

“…Complement cascade (CC) and bioactive sphingolipids (BS) are postulated to be involved in this process. Aim. The aim of this study was to evaluate plasma levels of CC cleavage fragments (C3a, C5a, and C5b9), sphingosine (SP), sphingosine-1-phosphate (S1P), and free hemoglobin (fHb) in AMI patients treated with primary percutaneous coronary intervention (pPCI) and stable coronary artery disease (SCAD) undergoing CABG. …”
Get full text

Modulation of intracellular kinase signaling to improve TIL stemness and function for adoptive cell therapy by Hao Feng, Ling Qiu, Zixiao Shi, Yao Sheng, Peipei Zhao, Di Zhou, Fei Li, Hailin Yu, Yanan You, Hui Wang, Ming Li, Shurong Zhu, Yan Du, Jun Cui, Jingwei Sun, Yarong Liu, Hua Jiang, Xin Wu

“…This calls for a robust expansion process to produce a large number of cells for clinical usage while at the same time maintaining favorable anti‐tumor function and memory phenotype. …”
Get full text

A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas. by Olivia Adams, Félice A Janser, Bastian Dislich, Sabina Berezowska, Magali Humbert, Christian A Seiler, Dino Kroell, Julia Slotta-Huspenina, Marcus Feith, Katja Ott, Mario P Tschan, Rupert Langer

“…Immunohistochemistry for the autophagy markers LC3B and p62 was applied on tumor tissue from 149 EAC patients treated with neoadjuvant chemotherapy, including pre- and post-therapeutic samples (62 matched pairs). …”
Get full text

Overall leukocyte levels link risk factors to Von Willebrand factor and Neutrophil Extracellular Traps in stroke thrombi: a Structural Equation Modeling analysis by Lin Shi, Chunxiao Wei, Guowei Ye, Panpan Zhao, Shiqiang Ma, Yiming Qi, Yiming Qi, Ruolin Zhou, Ruolin Zhou, Yaru Zhang, Yaru Zhang, Yan Zhang, Lingjie Meng, Weihang Xu, Chao Li, Shouchun Wang, Li Sun

“…This study uses overall leukocyte levels to identify potential links between risk factors and VWF, NETs in thrombi.MethodsThrombi samples and clinical data from 61 stroke patients treated at our hospital between 2017 and 2023 were collected. …”
Get full text