Dermatopontin promotes abdominal aortic aneurysm progression via the IL-1β-COL1A1 axis by YIN Huarun, ZHAO Ning, WU Zhiyuan, LI Yongjun, YIN Hongchao

“…Conclusions DPT promotes AAA progression by activating IL-1α/IL-1β inflammatory cytokines and inhibits COL1A1-mediated extra cellular matrix (ECM) remodeling.Integrin α3β1 is potentially involved in the regulation process.…”
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Microstructure Changes and Improvement in the Mechanical Properties of As-Cast AlSi7MgCu0.5 Alloy Induced by the Heat Treatment and ECAP Technique at Room Temperature by Miloš Matvija, Martin Fujda, Ondrej Milkovič, Marek Vojtko, Róbert Kočiško, Miroslav Glogovský

“…The crystal structure of present phases was confirmed by hard X-ray diffraction at Deutsches Elektronen-Synchrotron (DESY) in Hamburg and by the selected area electron diffraction (SAED) performed inside the transmission electron microscope (TEM). The heat-treated alloy was processed by ECAP at room temperature following route A. …”
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Morphological and Molecular Evaluation of a Gel Based on Hyaluronic Acid and Spermidine for Oral Regenerative Purposes by Dolaji Henin, Elena Canciani, Daniela Carmagnola, Stefano Ferrero, Gaia Pellegrini, Mariachiara Perrotta, Riccardo Sirello, Claudia Dellavia, Nicoletta Gagliano

“…HGFs were also analyzed through a wound healing assay. Gingival samples were obtained to set OCs and were treated with different HA-SP formulations (HA 0.2%; 1:0.5 HA-SP ratio; 1:5 HA-SP ratio) to evaluate the beneficial addition of SP to HA for epithelial tissue. …”
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Enhancing stroke prediction models: A mixing of data augmentation and transfer learning for small-scale dataset in machine learning by Imam Tahyudin, Ade Nurhopipah, Ades Tikaningsih, Puji Lestari, Yaya Suryana, Edi Winarko, Eko Winarto, Nazwan Haza, Hidetaka Nambo

“…We implemented the Synthetic Minority Over-sampling Technique for Nominal and Continuous to generate the artificial dataset. …”
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Expression of epithelial–mesenchymal transition driver brachyury and status of tumor-infiltrating CD8+ and FOXP3+ lymphocytes in predicting treatment responses to neoadjuvant chemo... by Kwan Ho Lee, Eun Young Kim, Yong Lai Park, Sung-Im Do, Seoung Wan Chae, Chan Heun Park

“…This retrospective study included a series of 44 consecutive patients treated between January 2011 and December 2015. All patient samples were obtained using core needle biopsy before neoadjuvant chemotherapy. …”
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Efficiency of four types of biochar to improve soil properties and decrease soil detachment in vulnerable hillslopes to rill erosion by Fateme Sedaghatkish, Safoora Asadi Kapourchal, Misagh Parhizkar

“…However, few studies have explored the impacts of different types of biochar on soil detachment rates in the hillslope rill erosion process due to overland flow in deforested areas. …”
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Modern Trends of Radiotherapy Cancer Oral Cavity by V. A. Titova, G. P. Snigireva, V. Y. Petrovsky, E. N. Telisheva

“…EGFRvIII weren’t revealed in one of analysed samples of tumor. The positive effect from target therapy erbitux wasn’t registered at one of two treated patients without mutations of EGFR.…”
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The influence of base glass thermal history and heat treatment on the ionic conductivity optimization in Li2O-Al2O3-TiO2-P2O5 glass-ceramics by Amirreza Fadaei, Pourya LotfiPoor, Omid Banapour Ghaffari, Bijan Eftekhari Yekta, Sara Ahmadi

“…Electrochemical impedance spectroscopy (EIS) demonstrated the highest ionic conductivity for samples treated at 850 °C, with values of 1.17 × 10−3 S/cm for G1-850 and 9.72 × 10−4 S/cm for G2-850. …”
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Possible Role of N-Methyl-D-Aspartate Glutamate Receptors in The Induction of Acrosome Reaction in Human Sperm by Hamid Reza Momeni, Elham Farjad, Abolghasem Naiemi, Tahereh Etemadi, Mohammad Hussein Abnosi, Niloufar Darbandi

“…Objective: Acrosome reaction is a receptor and Ca2+-dependent process. N-Methyl-D- aspartate (NMDA) glutamatereceptors are expressed in the human sperm and are involved in the Ca2+ influx. …”
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ARHGAP25: a novel player in the Pathomechanism of allergic contact hypersensitivity by Domonkos Czárán, Péter Sasvári, Kende Lőrincz, Krisztina Ella, Virág Gellén, Roland Csépányi-Kömi

“…After five days, ears were treated with 1% TNCB for elicitation. Swelling of the ears caused by edema formation was evaluated by measuring the ear thickness. …”
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Effects of cinnamic acid treatment on aroma of Kyoho grape during low temperature storage by HU Yulong, TIAN Shufen, WANG Chaoxia, WANG Rong, MA Chuang, JIANG Jianfu

“…The entire spraying process followed strict operational standards to ensure uniformity and consistency till drip. …”
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Clonal Micropropagation of Wild Berry Plants of the Genus Rubus by Sergey S. Makarov, Mikhail T. Upadyshev, Natalia R. Sungurova, Olga N. Tyukavina, Elena I. Kulikova, Irina B. Kuznetsova

“…In case of etiolated shoots (79–100%), it was the samples treated with 0.2% silver nitrate, 0.01% Nika 2, and 5% Lysoformin 3000 for 10 min. …”
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Mitigating Microfiber Pollution in Laundry Wastewater: Insights from a Filtration System Case Study in Galle, Sri Lanka by Mahagama Gedara Yohan Lasantha Mahagamage, Sachith Gihan Gamage, Rathnayake Mudiyanselage Shehan Kaushalya Rathnayake, Premakumara Jagath Dickella Gamaralalage, Matthew Hengesbugh, Thejani Abeynayaka, Chathura Welivitiya, Lahiru Udumalagala, Chathura Rajitha, Supun Suranjith

“…This study focused on a fully automatic front-loading washing machine (23 kg capacity) with a load of 12 kg of polyester–cotton blend serviettes (black and red). Samples (1 L each) were taken from both treated and untreated wastewater during four wash cycles, with a total of 100 L of water used for the process. …”
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Fabrication and wetting characteristics of copper thin film: An active layer for SPR-based sensor applications by Mohammad Kamal Hossain, Abdullah Aljishi, Firoz Khan, Anwar Ul-Hamid, Md Mosaddequr Rahman

“…A red shift in absorption edges (from 464 to 616 nm), a decrease in energy band gaps (from 2.38 to 1.54 eV) and an increase in Urbach energies (from 193 to 272 meV) were observed for those samples annealed at higher temperatures. Sessile drop tests were carried out to find the wetting contact angle (WCA) and to demonstrate the hydrophobicity of the thin film of pristine Cu and those treated at high temperatures. …”
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Determination of flumazenil in serum by liquid chromatography-mass spectrometry: Application to kinetics study in acute diazepam overdose by Đorđević Snežana, Jović-Stošić Jasmina, Kilibarda Vesna, Šegrt Zoran, Perković-Vukčević Nataša

“…Samples were prepared by solid-phase extraction on Oasis HLB cartridges with ethylacetate as extracting agens. …”
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Study on the Preparation and Corrosion Properties of Hydrotalcite Composite Permeation Layer via Plasma Electrolytic Carbonitriding by YANG Zhuolin, ZHAI Yanbo, CENG Shunke, PENG He, LE Chunpeng, WEI Ziwei

“…In order to improve the corrosion resistance of steel materials treated by plasma electrolytic infiltration，annealed 20 steel was used as the experimental substrate.Micro-nanopores formed during the plasma electrolytic carbonitriding process were utilized as containers to load magnesium-iron layered double hydroxides (Mg-Fe-LDHs) as a corrosion inhibitor，and the effects of Mg-Fe-LDHs on the corrosion performance of 20 steel were investigated.First，formamide was used as the carbon and nitrogen source，and KCl was used as the conductive salt.These components were mixed with deionized water to form an electrolyte.Then，the samples were treated at a constant DC pulse voltage of 220 V for 9 min to produce a carbonitrided layer (denoted as PEC/N samples).Subsequently，the PEC/N samples were immersed in a Mg-Fe-LDHs precursor solution containing urea，MgSO4 and Na2CO3，and hydrothermally crystallized at 140 ℃for 10 h to obtain a composite infiltration layer (denoted as PEC/N-LDHs samples).The performance of the composite infiltration layers was analyzed using a microhardness tester，scanning electron microscopy (SEM)，X-ray diffraction (XRD) and electrochemical testing.Results showed that the microhardness of the composite infiltration layer reached approximately 900 HV，which was 4.6 times higher than that of the substrate.The carbonitrided layer of the PEC/N samples was about 20 μm，with a smooth and flat cross-section but a rough，porous and honeycomb-like surface.After hydrothermal synthesis of LDHs，the surface became smooth，lacking a visible honeycomb structure，and a large number of flake-like crystalline deposits appeared on the surface.The XRD spectra of the PEC/N samples showed absorption peaks corresponding to Fe3C，Fe5C2，α-Fe and Fe3N phases.After the in-situ loading of Mg-Fe-LDHs，new absorption peaks corresponding to the (003)，(006) and (009) crystal planes of Mg-Fe-LDHs appeared in the XRD spectra of the PEC/N-LDHs samples.Combined with SEM morphology analysis，it was confirmed that Mg-Fe-LDHs were successfully loaded，presenting a flake-like structure.Compared with 20 steel，the PEC/N samples exhibited improved corrosion potential (Ecorr) and corrosion current density (Jcorr)，reaching－0.451 V and 75.22 μA/cm2，respectively，although the lowfrequency impedance modulus (｜Z ｜0.01 Hz) showed no significant increase，reaching only 998.5 Ω·cm2.After loading Mg-Fe-LDHs，the PEC/N-LDHs samples demonstrated further improvements，with Ecorr，Jcorr and ｜Z ｜0.01 Hz reaching－0.355 V，39.11 μA/cm2 and 6 586.0 Ω·cm2，respectively，showing significant enhancement compared to both 20 steel and PEC/N samples.These results indicated that plasma electrolytic carbonitriding treatment of 20 steel could produce a carbonitrided layer with high hardness.Additionally，the hydrothermal loading of LDHs further improved the corrosion resistance of the composite infiltration layer without affecting its hardness.The PEC/N-LDHs composite infiltration layer thus achieved both high hardness and superior corrosion resistance.…”
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Metagenomics combined with activity-based proteomics point to gut bacterial enzymes that reactivate mycophenolate by Joshua B. Simpson, Josh J. Sekela, Amanda L. Graboski, Valentina B. Borlandelli, Marissa M. Bivins, Natalie K. Barker, Alicia A. Sorgen, Angie L. Mordant, Rebecca L. Johnson, Aadra P. Bhatt, Anthony A. Fodor, Laura E. Herring, Hermen Overkleeft, John R. Lee, Matthew. R. Redinbo

“…Mycophenolate mofetil (MMF) is an important immunosuppressant prodrug prescribed to prevent organ transplant rejection and to treat autoimmune diseases. MMF usage, however, is limited by severe gastrointestinal toxicity that is observed in approximately 45% of MMF recipients. …”
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Characteristic of Viral and Bacterial Contaminationin Objects of the Infection Hospital Environment of the Hospital for the Treatment of Patients with COVID-19 During the Pandemic... by I. A. Egorov, S. S. Smirnova, V. A. Mishchenko, I. V. Vialykh, A. Yu. Markarian, N. N. Zhuikov, S. V. Romanov, A. V. Ponomareva, I. V. Chistiakova, A. S. Kiliachina, O. Yu. Averianov, V. A. Smirnova, А. N. Bolshakova, E. V. Vernik, N. A. Pushkareva, A. V. Semenov

“…Sample collection was performed during three days (Tuesday, Thursday, Sunday) at 20 unified sampling points: in the area where patients general hospital area as well as from the outer surface of personal protective equipment for medical personnel (overalls, gloves). …”
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Likelihood of Leveraging Augmented Reality Technology to Promote HIV Prevention and Treatment Among Adolescent Girls and Young Women in Cameroon: Cross-Sectional Survey by Zhao Ni, Intan Maharani Sulistyawati Batubara, Jackson Jr Nforbewing Ndenkeh, Georges Bediang, Habakkuk Yumo, Xuehong Zhang, Sunyong Oh, Yuchen Zhao, LaRon E Nelson

“…The study findings will lay the groundwork for developing AR-based interventions to prevent and treat HIV in Cameroon and beyond. MethodsThis was a cross-sectional survey conducted in Yaounde, Cameroon, in which 637 adolescent girls and young women were recruited using a combination of multistage cluster and snowball sampling techniques. …”
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UV-ageing effects on polystyrene microplastics surface polarity and transport in soils by Leila Shafea, Marc-O. Goebel, Susanne K. Woche, Stephan Peth

“…ATR-FTIR results revealed that UV irradiation induced a transformation of PS-MP surfaces with especially the appearance of a carbonyl (C=O) peak due to C-H bond breaking during the oxidation process. The increasing presence of oxygen-containing functional groups in UV-treated PS-MP led to an increasing negative surface charge and zeta potential and enhanced PS-MP transport through the quartz sand column. …”
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