Effects of vitamin D3 supplementation on the recovery of hospitalized burn patients: a randomized double-blind controlled trial by Elahe Ghadimi, Roozbeh Rahbar, Elham Jafarzade, Anahita Mansoori

“…Methods Fifty-four patients participated in a randomized controlled trial. Eighteen patients were randomly assigned to group C (control, received gelatin soft gel as placebo), 18 patients to group D1 (received 1000 IU/day vitamin D), and 18 patients to group D2 (received 3000 IU/day vitamin D). …”
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Physical activity interventions in adult kidney transplant recipients: an updated systematic review and meta-analysis of randomized controlled trials by Roseanne E. Billany, Nicolette C. Bishop, Ellen M. Castle, Matthew P. M. Graham-Brown, Sharlene A. Greenwood, Courtney J. Lightfoot, Thomas J. Wilkinson

“…Despite new literature, there is still a need for long-term larger sampled RCTs and more detailed reporting of intervention details and program adherence.…”
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Changes in gut microbiota following supplementation with chitosan in adolescents with overweight or obesity: a randomized, double-blind clinical trial by Somaye Fatahi, Mohammad Hassan Sohouli, Koroush Vahidshahi, Pejman Rohani, Majid Safa, Masoud Salehi, Mihnea-Alexandru Găman, Farzad Shidfar

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Fu’s subcutaneous needling approach versus electroacupuncture for knee osteoarthritis: protocol for comparative effectiveness and safety randomized controlled trial by Linan Liu, Linan Liu, Jian Sun, Hu Li, Hu Li, Zhaojian Zheng, Jin Lu, Qin Lyu, Tianyu Bai

“…However, studies on the difference in clinical efficacy of FSN in treating KOA still lack clinical validation with large samples. The purpose of this study was to provide high-level clinical evidence for the clinical management of KOA by comparing the multicenter differences between FSN and EA in the treatment of this disease.Methods and analysisThis study is a prospective, multicenter, randomized controlled trial to compare the efficacy and safety of FSN with EA in the treatment of KOA. …”
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Implementation and Evaluation of a Home-Based Pre-Exposure Prophylaxis Monitoring Option: Protocol for a Randomized Controlled Trial by Chase Cannon, Katherine Holzhauer, Matthew Golden

“…Among the 49 participants randomized to the HB-PrEP option, 33 (67%) chose to self-collect samples at home at least once, of whom 27 (82%) successfully returned test kits for HIV and STI testing. …”
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Measured Resection as Gap Balance Method in Mobile‐Bearing Medial Unicompartmental Knee Arthroplasty: A Randomized Controlled Trial by Qian Liu, Jianhua Ren, Wenhui Zhang, Tangzhao Liang, Zhe Wang, Siwei Xie, Yuhang Li, Jianfeng Hou, Kun Wang, Ronghan He

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Randomized Controlled Trial of a Novel Cementless vs. Cemented Total Knee Arthroplasty: Early Clinical and Radiographic Outcomes by Enze Zhao, Xiaoyan Zhu, Haiwei Tang, Zhenyu Luo, Weinan Zeng, Zongke Zhou

“…Continuous data were analyzed for significance using independent‐samples t‐test or the Mann–Whitney U test and categorical data were analyzed using chi‐squared or Fisher's exact test. …”
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Exploring the Impact of the Caring Contacts Intervention on the Stress and Distress of Veterans and Service Members: Protocol for a Randomized Controlled Trial by Barbara Wright, Anna Evanson, Cameron Casey, Keyne C Law, Andrew H Rogers, Katherine Anne Comtois

“…It reduces suicide risk among individuals with recent suicidal ideation or attempts and has demonstrated acceptability in military and veteran samples, but little is known about the mechanisms of Caring Contacts or its applicability to populations who are not suicidal. …”
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Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis. by Petroula Proitsi, Michelle K Lupton, Latha Velayudhan, Stephen Newhouse, Isabella Fogh, Magda Tsolaki, Makrina Daniilidou, Megan Pritchard, Iwona Kloszewska, Hilkka Soininen, Patrizia Mecocci, Bruno Vellas, Alzheimer's Disease Neuroimaging Initiative, Julie Williams, GERAD1 Consortium, Robert Stewart, Pak Sham, Simon Lovestone, John F Powell

“…Limitations of this study include the small proportion of lipid variance explained by the GRS, biases in case-control ascertainment, and the limitations implicit to Mendelian randomization studies. Future studies should focus on larger LOAD datasets with longitudinal sampled peripheral lipid measures and other markers of lipid metabolism, which have been shown to be altered in LOAD. …”
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How reliable is the labeling of a commercial phytosteroid product? A 12-week randomized double-blind training study by Joshua Dissemond, Tim Havers, Steffen Held, Stephan Geisler, Tihomir Kostov, Patrick Diel, Svea Türschmann, Maria K. Parr, Eduard Isenmann

“…Liver and kidney function, along with endocrine parameters, were measured via blood samples pre- and post-intervention. Additionally, the concentration of 20E and DSG in the product was measured by LC-MS/MS, and its biological activity was evaluated using C2C12 cells after the intervention. …”
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Strengthening the success rate of suprapubic aspiration in infants by integrating point-of-care ultrasonography guidance: A parallel-randomized clinical trial. by Sadroddin Mahdipour, Seyedeh Nastaran Seyed Saadat, Hamidreza Badeli, Afagh Hassanzadeh Rad

“…A sterile collection of urine samples using suprapubic aspiration (SPA) and bladder catheterization (BC) is helpful for rapid and accurate diagnosis of UTI in infants. …”
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Glucosamine supplementation contributes to reducing the risk of type 2 diabetes: Evidence from Mendelian randomization combined with a meta-analysis by Shuai Zhou, Peiwen Zhou, Tianshi Yang, Junzhuo Si, Wenyan An, Yanfang Jiang

“…Methods The glucosamine supplementation–related genome-wide association study dataset was obtained from the MRC Integrative Epidemiology Unit consortium, whereas type 2 diabetes–related genome-wide association study datasets were obtained from the FinnGen consortium (discovery) and Xue et al.’s meta-analysis (validation). Two-sample Mendelian randomization analyses were performed separately in the discovery and validation datasets, followed by meta-analysis and multivariable Mendelian randomization analyses to verify the robustness of the results of two-sample Mendelian randomization. …”
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Improving the Bioactivities of Apricot Kernels Through Fermentation: Investigating the Relationship Between Bioactivities, Polyphenols, and Amino Acids Through the Random Forest Re... by Zhiyu Zhao, Kevin Kantono, Rothman Kam, Thao T. Le, Eileen Kitundu, Tony Chen, Nazimah Hamid

“…The findings indicated that apricot kernels fermented with <i>Lactiplantibacillus plantarum</i> exhibited increased antioxidant activity, as assessed by the FRAP and CUPRAC methods, and an increased TPC compared to naturally fermented samples. The CUPRAC activity increased significantly from 1.03 to 1.82 mg of ascorbic acid per gram of sample on day 7, and the FRAP activity increased from 4.9 to 12.2 mg of ascorbic acid per gram of sample on day 3 of fermentation. …”
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Internet-based digital intervention to support the self-management of hypertension compared to usual care: results of the HALCYON randomized controlled trial by Björn Meyer, Antje Riepenhausen, Linda T. Betz, Kamila Jauch-Chara, Alexander Reshetnik

“…Results The study's statistical power was limited due to a smaller sample size (N = 102) than the a priori target sample size (N=676). …”
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Flood susceptibility estimation using randomization-based machine learning models. A case study at the Putna river basin, Romania by Romulus Costache

“…In this context, in the present study, the following 3 hybrid models were applied to determine flood susceptibility in Putna river basin, Romania: Randon Committee-Weights of Evidence (RC-WOE), Random SubSpace-Weights of Evidence (RSS-WOE) and Randomizable Filtered Classifier – Weights of Evidence (RFC – WOE). 14 flood predictors and 192 flood locations (divided into 70% training sample and 30% validating sample) were used as input data in the 3 models. …”
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Bridging the Energy Divide: An Analysis of the Socioeconomic and Technical Factors Influencing Electricity Theft in Kinshasa, DR Congo by Patrick Kankonde, Pitshou Bokoro

“…This study analyzes the determinants influencing electricity theft in Kinshasa, the Democratic Republic of Congo, using a logistic regression model applied to 385 observations, which includes random bootstrapping sampling for enhanced stability and power analysis validation to confirm the adequacy of the sample size. …”
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Morphometric characterization of the indigenous goats of Odisha, India by VENKATESH K M, GOWTHAMAN T, CHINMOY MISHRA

“…The results of the present study suggest that random forest analysis can also be used to classify animal populations, provided it is validated by a large sample size. …”
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Genetically Predict Diet‐derived Antioxidants and Risk of Neurodegenerative Diseases Among Individuals of European Descent: A Mendelian Randomization Study by Qing‐Qing Duan, Wei‐Ming Su, Xiao‐Jing Gu, Jiang Long, Zheng Jiang, Kang‐Fu Yin, Wei‐Chen Cai, Bei Cao, Li‐Yi Chi, Xia Gao, Ju‐Rong Li, Yong‐Ping Chen

“…In this study, we employed a two‐sample Mendelian randomization (MR) analysis to investigate the potential causal relationship between elevated circulating antioxidant levels and the risk of NDDs. …”
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Evaluation of the Role of PRP in Acute Tibial Shaft Fractures Fixation With IM Nail: A Double-Blinded Randomized Controlled Trial by Wittawat Boonyanuwat, BhupaAk Engkapawastr, Pinkawas Kongmalai

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Continuous prediction of human knee joint angle using a sparrow search algorithm optimized random forest model based on sEMG signals by Liuyi Ling, Zhu Lin, Bin Feng, Liyu Wei, Li Jin, Yiwen Wang

“…This study proposed a random forest (RF) model optimized by the sparrow search algorithm (SSA) for achieving continuous motion prediction of the lower limb knee joint based on surface electromyography(sEMG) under various motion modes. …”
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