Hepatorenal Protective Effects of Hydroalcoholic Extract of Solidago canadensis L. against Paracetamol-Induced Toxicity in Mice by Omid Rahimi, Nilufar Asadi Louie, Alireza Salehi, Firouz Faed Maleki

“…On the seventh day (24 hours after paracetamol injection), blood samples were collected to measure the serum level of creatinine, uric acid, blood urea nitrogen (BUN), total protein, albumin, alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), and total and direct bilirubin, and liver and kidney tissues were also sampled for histopathological examination. …”
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Non-targeted Metabolomics-based Exploration of
Radiation-induced Metabolic Alterations in Mouse Lung Epithelial Cells by Hao FAN, Xiangwei GE, Xin ZHOU, Yao LI, Qiaowei LIU, Yi HU

“…Metabolomic analysis of the samples was performed by liquid chromatograph mass spectrometer (LC/MS). …”
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Hand washing in operating room: a procedural comparison by Alessia Stilo, Gianmarco Troiano, Lucia Melcarne, Maria Eufemia Gioffrè, Nicola Nante, Gabriella Messina, Pasqualina Laganà

“…Then, we measured the number of colony forming units per mL (CFU/mL) and calculated the percentage of microbial load reduction. RESULTS 211 samples have been considered for statistical analysis: in 42 samples, in fact, initial microbial load was lower than after washing. …”
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Anti-Early Stage of Bacterial Recolonization Effect of Curcuma longa Extract as Photodynamic Adjunctive Treatment by Doosadee Hormdee, Weena Rinsathorn, Subin Puasiri, Paiboon Jitprasertwong

“…Samples of the subgingival microbiota were obtained in each visit. …”
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Evaluating the Hepatoprotective Potential of Ginger Ethanolic Extract Against Lambda-Cyhalothrin-Induced Toxicity in Male Rats by Mustafa Q Mustafa, Zainab JM Jawad

“…Additionally, liver samples were collected for histopathological‎ ‎examination‎.‎ …”
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Meta-Transcriptomic Response to Copper Corrosion in Drinking Water Biofilms by Jingrang Lu, Ian Struewing, Nicholas J. Ashbolt

“…This study was conducted to evaluate the impact of upstream Cu pipe materials on downstream viable community structures, pathogen populations, and metatranscriptomic responses of the microbial communities in drinking water biofilms. Randomly transcribed cDNA was generated and sequenced from downstream biofilm samples of either unplasticized polyvinylchloride (PVC) or Cu coupons. …”
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Integrative multi-omics data from early development to identify the genes and cell types underlying attention-deficit/hyperactivity disorder by Shufen Jiao, Li Bao, Xiaowen Lu, Yong Wu, Yichen Li

“…Methods We applied the summary data-based Mendelian randomization (SMR) approach to integrate expression quantitative trait loci (eQTL) data derived from bulk post-mortem tissues, fetal brain tissues, and single-cell types from induced pluripotent stem cell (iPSC)-derived neurons and post-mortem brain samples with ADHD GWAS data. …”
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Detection of Methicillin Resistant Staphylococcus aureus (MRSA) from Hospital Instruments by Aminu, A.I., Abdullahi, S., Usman M.I.

“…It is a descriptive hospital based study and 74 samples were randomly collected from swabbed instruments from five Hospitals in Kano, Nigeria. …”
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Gene frequencies and polymorphism of the MNS blood group system in the Han population of voluntary blood donors in Suzhou by XU Zihao, FU Xiaoyan, LIU Zhen, JIANG Jia, JIN Yiming

“…[Methods] A total of 8 034 whole blood samples were randomly collected from Han blood donors at our station from October 2023 to June 2024. …”
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19- THE PROTECTIVE ROLE OF CALCIUM CHLORIDE AND VITAMIN C FOR THYROID FUNCTION IN ADULT MALE RATS EXPOSED TO SODIUM FLUORIDE by Sumayah Faruq Kasim, Jassim M. A. Alkalby

“…At the end of the experiment, animals were sacrificed under anesthesia. Blood samples were taken and the serum was separated for the study of the thyroid hormones, and tissue samples of the thyroid gland were taken for histological changes. …”
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Enhancing Feed Efficiency and Growth in Early-Fattening Hanwoo Steers Through High-Energy Concentrate Feeding by Emmanuel Onche, Hyunjin Cho, Andrian Deguinion Rangandang, Namkyu Kang, Suheon Kim, Hongdae Kim, Seongwon Seo

“…Body weights were measured every four weeks. In week 12, rumen samples were collected, followed by fecal and blood samples. …”
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Seroepidemiological Study of Human Toxoplasmosis in Females in Ardabil City, 2019-2020 by Roya Houshmandi Khaneghahi, Shahram Habibzadeh, Farhad Pourfarzi, Behnam Mohammadi Ghalehbin

“…The designed questionnaire was completed and blood samples were taken. Serum samples were tested using an ELISA kit to detect anti-Toxoplasma IgG antibody. …”
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Correlations between three ELISA protocols measurements of RTS,S/AS01-induced anti-CSP IgG antibodies. by Robert M Mugo, Benedict Orindi, Faiz M Shee, Duncan Bellamy, Jedidah Mwacharo, Katie J Ewer, Philip Bejon, Francis M Ndungu

“…<h4>Methods</h4>196 plasma samples were randomly selected from the 447 samples collected during the RTS,S/AS01 phase IIb trial in 2007 from Kenyan children aged between 5-17 months. …”
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Impact of sodium metabisulfite on the structural, hematological, and enzyme dynamics in liver and spleen of Wistar rats by Nathaniel Amedu, Habeebullahi Abdur-Rahman

“…The administration was conducted orally over a period of 28 days, after which the rats were euthanized for tissue collection. Blood samples were obtained to analyze red blood cell (RBC) count, hemoglobin (Hb) count, platelets (PLT) count, and white blood cell (WBC) count, while liver and spleen tissue samples were collected for alkaline phosphatase (ALP), alanine aminotransferase (ALT), and aspartate aminotransaminase (AST) assays, along with histopathological examination using haematoxylin and eosin staining. …”
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Effects of sinomenine on PI3K/mTOR signaling pathway and mesangial hyperplasia in rats with adriamycin-induced nephropathy by Liu Yue, Li Peng-yuan, Zhang Qing-hua, Yan Dan

“…Objective To explore the effect of sinomenine on the signal pathway of phosphatidyl-3 kinase（PI3 K）/mammalian target of rapamycin（mTOR）and mesangial hyperplasia in renal tissue of rats with adriamycin-induced nephropathy and elucidate its protective mechanism.Methods A total of 50 SD rats were selected, 10 rats were randomly injected with normal saline via caudal vein as control group, the other 40 rats were injected with adriamycin 5 mg/kg via caudal vein for 7 days to prepare nephrotic syndrome（NS）model.After successful modeling, the rats were randomly divided into the groups of model（NS）,sinomenine low-dose（25 mg/kg）,medium-dose（50 mg/kg）and high-dose（100 mg/kg）（n=10 each）.Control and NS groups received normal saline through abdominal cavity and sinomenine groups were given corresponding doses of drugs once daily for 28 days.At 24 hours after the last administration, blood and urine samples of rats in each group were collected and rats sacrificed, renal tissue samples harvested, serum creatinine（Scr）and urea nitrogen（BUN）were measured by enzyme-linked immunosorbent assay（ELISA）;24-hour urine protein was detected by Coomassie brilliant blue staining; hematoxylin-eosin staining（HE）was utilized for analyzing the pathological changes of kidney and mesangial matrix index（M/G）;transmission electron microscopy for observing the thickening of glomerular basement membrane of kidney; Western blot for detecting the expressions of p-PI3 K/PI3 K,p-mTOR/mTOR,fibronectin（FN）and type IV collagen（COL4）in renal tissue.Results As compared with control group, there were pathological damages such as the increase of glomerular mesangial matrix, the expansion of renal tubule lumen and severe thickening of glomerular basement membrane.M/G and renal function indicators Scr, BUN,24-hour urine protein and renal tissue were elevated.The protein expressions of p-PI3 K,p-mTOR,FN and COL4 rose markedly in NS group（P<0.05）.As compared with NS group, sinomenine high/medium/low dose groups alleviated pathological damage such as glomerular basement membrane thickening, M/G,Scr, BUN,24-hour urine protein, renal tissue p-PI3 K,expressions of mTOR,FN and COL4 proteins declined markedly in sinomenine low/medium/high-dose groups（P<0.05）.As compared with low-dose sinomenine group, glomerular basement membrane thickening was the least pathologically damaged and M/G,Scr, BUN,24-hour urine protein, renal tissue p-PI3 K,p-mTOR,FN and COL4 declined markedly in sinomenine medium/high-dose group（P<0.05）.Conclusions Sinomenine may inhibit the activation of PI3 K/mTOR signaling pathway, reduce the proliferation of glomerular mesangial cells and delay the process of nephrotic syndrome.…”
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Study of the effect of food on the bioavailability, safety and tolerability of Aterixen^® 100 mg tablet in healthy volunteers by V. B. Vasilyuk, Yu. A. Dzhurko, A. A. Globenko, L. N. Schitov, V. N. Shabrov, M. A. Pasko, O. V. Kovchan, A. V. Kapashin, A. I. Bashkatova

“…In each study period, serial blood samples were collected before and throughout 12 h after administration of the study drug. …”
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Reproductive Characteristics of the Pond-Farmed Sultan Fish (Leptobarbus hoevenii) by Sajeenuth Srithongthum, Hsein-Loong Au, Thumronk Amornsakun, Poramat Musikarun, Wen Jye Mok, Nur Fatihah Abdul Halid, Gunzo Kawamura, Leong Seng Lim

“…Twenty male and female pond-farmed L. hoevenii broodstock were obtained to measure their total length (TL), body weight (BW) and gonad weight to calculate the GSI. Ten females were randomly sampled from the 20 to determine their fecundity. …”
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Demographic characteristics, incidence and severity of onion basal rot in the Upper East Region of Ghana by Aminu Osman, Muntala Abdulai, Salim Lamini, Kwadwo Gyasi Santo

“…A survey was conducted in 2022 in three purposefully sampled districts and a municipality in the region to determine the incidence and severity of the disease and to assess the perception and knowledge of farmers on the spread and control of the disease in the Region. …”
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Quality of antidiabetic medicines in 13 sub-Saharan African countries: a cross-sectional surveyResearch in context by Marie Antignac, Roland N'Guetta, Philippe Henri Secretan, Bernard Do, Meo Stephane Ikama, Jean Bruno Mipinda, Ibrahim Ali Toure, Jean Laurent Takombe, Yves Lubenga, Mouhamadoul Mounir Dia, El Bou Isselmou Boukhary Ould, Maxwell Dalaba, Naby Moussa Balde, Amadou Kake, Ely Cheikh Ibrahima Sy, Pauline Cavagna, Marie Cécile Perier, Eugène Sobngwi, Pr Badara Cisse, Christian Boitard, J.P. Empana, I. Bara Diop, Maimouna Ndour Mbaye, Xavier Jouven

“…Out of the 1673 (of 4951 collected) drug samples randomly tested, 28·0% (n: 468, 95% CI [22·3–33·0]) failed to meet standards related to the expected content of active ingredients (B: 27·2% 95% CI [21·5–32·0]; C: 0·8% 95% CI [0·2–3·5]), with more samples showing underdosage (19·31% 95% CI [14·8–24·3]) than overdosage (8·67% 95% CI [5·3–12·5]). …”
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Blockade of the JNK Signalling as a Rational Therapeutic Approach to Modulate the Early and Late Steps of the Inflammatory Cascade in Polymicrobial Sepsis by Gabriele Pizzino, Alessandra Bitto, Giovanni Pallio, Natasha Irrera, Federica Galfo, Monica Interdonato, Anna Mecchio, Filippo De Luca, Letteria Minutoli, Francesco Squadrito, Domenica Altavilla

“…Two other animals were sacrificed 4 or 18 hours after surgical procedures; lung and liver samples were collected for biomolecular and histopathologic analysis. …”
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