Impacts of soil physical and mechanical behaviors under different tillage depths for agrotechnical operation in Bukito, Sidama, Ethiopia by Samuel Ketena, Girma Gebresenbet, Kishor Purushottam Kolhe, Miheret Dananto, Yared Seifu, Markos Mathwos

“…The objective was to identify these properties under varying agro-technical soil depth conditions. Randomized Complete Block Design (RCBD) field experimental design was spotted to take soil samples using appropriate sample equipment and further lab analysis was conducted. …”
Get full text

Assessment of adverse childhood experiences in women: a study of reliability and predictive validity of self-reporting versus medical records abstraction in an American population by Walter A Rocca, Kent R Bailey, Liliana Gazzuola Rocca, Carin Y Smith, Michelle M Mielke, Kejal Kantarci, Dmitry Esterov, Ekta Kapoor, Jennifer R Geske

“…Objective To study the reliability and validity of adverse childhood experiences (ACE) scores measured using a questionnaire versus abstraction of medical records, and to test whether the scores vary by history of bilateral oophorectomy, or by age and presence of anxiety or depressive symptoms at the time of questionnaire administration.Design The study involved a reliability component and a predictive validity component.Setting A population-based sample in Olmsted County, Minnesota, was derived from the Mayo Clinic Cohort Study of Oophorectomy and Aging-2.Participants We included 198 women who underwent premenopausal bilateral oophorectomy for a non-malignant indication between 1988 and 2007 and 174 referent women of the same age randomly sampled from the general population (total of 372 women). …”
Get full text

Effects of Yeast β-Glucan Supplementation on Calf Intestinal and Respiratory Health by Jiamin Wang, Fang Yan, Meng Xiong, Jieru Dong, Wenqian Yang, Xiurong Xu

“…Obviously, the PO group sample points were more clustered. In conclusion, this study highlights the potential of yeast β-glucan-induced trained immunity to improve calf health during the suckling period. …”
Get full text

Improving Large Language Models’ Summarization Accuracy by Adding Highlights to Discharge Notes: Comparative Evaluation by Mahshad Koohi Habibi Dehkordi, Yehoshua Perl, Fadi P Deek, Zhe He, Vipina K Keloth, Hao Liu, Gai Elhanan, Andrew J Einstein

“…MethodsTo test our hypothesis, we randomly sampled 15 discharge notes from the MIMIC III database and highlighted their detailed information using an interface terminology we previously developed with machine learning. …”
Get full text

Evaluation of Setting Time, Compressive Strength, Microleakage and Antibacterial Properties of Nano Hydroxyapatite Incorporated GIC: An In-vitro Study by Akshada Chougaonkar, Updesh Masih, Abhilasha Manker, Neelesh Gautam, Nidhi Soni

“…For antibacterial properties, 50 samples (n=10) were taken for each strain, i.e., Strain A: S. mutans and Strain B: L. fermentum and the disk diffusion method was employed. …”
Get full text

Exploring the role of topography in the sputtering process of tungsten by GyM helium plasma by Andrea Uccello, Gabriele Alberti, Matteo Pedroni, Anna Cremona, Francesco Ghezzi, Miriam Saleh, Espedito Vassallo, Luigi Bana, David Dellasega, Matteo Passoni, Carlo Tuccari, Davide Vavassori, Antti Hakola, Marcin Rasinski, Juri Romazanov, the GyM Team

“…Surfaces with varying roughness, from sub-nanometer to approximately 1 µ m, and different textures, including random-like and regular configurations, were studied. …”
Get full text

Identification and predictive machine learning models construction of gut microbiota associated with lymph node metastasis in colorectal cancer by Yongzhi Wu, Chengen Deng, Zigui Huang, Yongqi Huang, Chuanbin Chen, Mingjian Qin, Zhen Wang, Fuhai He, Shenghai Liu, Rumao Zhong, Jun Liu, Chenyan Long, Jungang Liu, Weizhong Tang, Xiaoliang Huang

“…By conducting 16S rRNA sequencing on fecal samples from 147 CRC patients and combining it with the linear discriminant analysis effect size algorithm, we successfully identified significant differences in the gut microbiota between patients with LNM and those with no lymph node metastasis (NLNM). …”
Get full text

Transition experiences of adolescents and young adults working with a patient navigator by Daniella San Martin-Feeney, Sophie Samborn, Brooke Allemang, Megan Patton, Zoya Punjwani, Ken Pfister, Laurel Ryan, Gregory M.T. Guilcher, Lorraine Hamiwka, Scott Klarenbach, Eddy Lang, Kerry McBrien, Alberto Nettel-Aguirre, Danièle Pacaud, Jorge Pinzon, Shannon D. Scott, Lonnie Zwaigenbaum, Curtis Perrott, John Andersen, Gail Andrew, Andrew S. Mackie, Susan Samuel, Gina Dimitropoulos

“…Methods: A qualitative study was conducted within a pragmatic randomized controlled trial. A purposive sample was recruited of AYA with diverse diagnostic and demographic characteristics who worked with the PN and/or their caregivers. …”
Get full text

Efficacy and Safety of 10‐Day Versus 14‐Day Bismuth‐Containing Quadruple Therapy for Helicobacter pylori Eradication: A Systematic Review and Meta‐Analysis by Najam Gohar, Zoya Ejaz, Faizan Ahmed, Abdul Rafay Ahmed, Muhammad Abdullah Humayun, Momna Nisar, Muhammad Ali Mushtaq, Aanusha Ghouri, Fatima Zafar, Hira Khalid, Sania Afzal, Hammad Khan, Huzaifa Ahmed Cheema, Muhammad Shahzil, Essam Rashad, Rehmat Ullah Awan, Prasun K. Jalal

“…Future research comparing similar drug doses with larger sample sizes and longer patient follow‐ups can improve the quality of results.…”
Get full text

Mass treatment with azithromycin for trachoma: when is one round enough? Results from the PRET Trial in the Gambia. by Emma M Harding-Esch, Ansumana Sillah, Tansy Edwards, Sarah E Burr, John D Hart, Hassan Joof, Mass Laye, Pateh Makalo, Ahmed Manjang, Sandra Molina, Isatou Sarr-Sissoho, Thomas C Quinn, Tom Lietman, Martin J Holland, David Mabey, Sheila K West, Robin Bailey, Partnership for Rapid Elimination of Trachoma (PRET) study group

“…<h4>Methods</h4>In a community randomized trial with a factorial design, we randomly assigned 48 communities in four Gambian districts, in which the prevalence of trachoma was known or suspected to be above 10%, to receive annual mass treatment with expected coverage of 80-89% ("Standard"), or to receive an additional visit in an attempt to achieve coverage of 90% or more ("Enhanced"). …”
Get full text

Endoscopic Ultrasound-Guided Fine Needle Biopsy with Stylet and Suction Versus No Stylet No Suction for the Diagnosis of Pancreatic and Non-Pancreatic Lesions by Ahmed MA, Ahmed MY, Shaaban HE, Abou Elenin SEA, El-Habashi AA, Belabbes F, Tag-Adeen M, Abdellatef A, Okasha HH

“…Each lesion was sampled twice using an EUS-FNB 22-gauge Franseen-tip needle (Acquire; Boston Scientific, USA); one sample was collected with stylet and suction, while the other with no stylet no suction technique. …”
Get full text

Evaluation of aggrephagy markers in myofibrillar myopathies by Eliana Iannibelli, Alessandra Ruggieri, Antonello Maruotti, Franco Salerno, Marta Cheli, Alessandra Carnazzi, Lucia Nicolini De Gaetano, Giorgia Riolo, Sara Bortolani, Pietro Riguzzi, Sara Vianello, Gioia Merlonghi, Luca Bello, Matteo Garibaldi, Massimiliano Filosto, Stefano Carlo Previtali, Giorgio Tasca, Gaetano Vattemi, Paola Tonin, Elena Pegoraro, Sara Gibertini, Lorenzo Maggi

“…Our study aims to investigate the potential pathogenic role of aggrephagy in 52 muscle samples from an Italian MFM multicentric cohort. We measured, the percentage of positive areas of key aggrephagy proteins by immunofluorescence staining, of sequestosome 1 (p62/SQSTM1), Neighbor of BRCA1 Gene 1 (NBR1), and ubiquitinated proteins (FK2) in 11 DES-, 6 DNAJB6-, 5 FLNC-, 18 MYOT- and 12 TTN-mutated patients. …”
Get full text

Early Immunological and Inflammation Proteomic Changes in Elderly COVID-19 Patients Predict Severe Disease Progression by Shiyang Liu, Wen Xu, Bo Tu, Zhiqing Xiao, Xue Li, Lei Huang, Xin Yuan, Juanjuan Zhou, Xinxin Yang, Junlian Yang, De Chang, Weiwei Chen, Fu-Sheng Wang

“…Olink proteomic analysis was performed on admission serum from 40 propensity score-matched samples, with differentially expressed proteins (DEPs) validated by cytometric bead array (CBA) in 178 patients. …”
Get full text

Systematic review and meta-analysis of polycystic ovary syndrome and mental health among Black Asian Minority Ethnic populations by Gayathri Delanerolle, Salma Ayis, Vanya Barzilova, Peter Phiri, Priyanka Jagadeesan, Yutain Zeng, Sandali Ranaweera, Ashish Shetty, Nyla Haque, Debasish Kar, Kingshuk Majumder, Shanaya Rathod, Vanessa Raymont, Jian Qing Shi, Dharani K. Hapangama

“…The finalised dataset was analysed using statistical methods such as random-effect models, subgroup analysis, and sensitivity analysis. …”
Get full text

The characteristics of tissue microbiota in different anatomical locations and different tissue types of the colorectum in patients with colorectal cancer by Lei Liu, Jianguo Shi, Hui Wang, Hansong Du, Jia Yang, Kai Wei, Zhuohui Zhou, Moli Li, Shuai Huang, Lifang Zhan, Guolong Li, Yongling Lv, Hexiao Shen, Wei Cai

“…In this study, we collected 57 samples from 19 CRC patients, comprising cancerous tissue, paracancerous tissue, and normal mucosa. …”
Get full text

Handling of missing component information for common composite score outcomes used in axial spondyloarthritis research when complete-case analysis is unbiased by Christos Polysopoulos, Stylianos Georgiadis, Lykke Midtbøll Ørnbjerg, Almut Scherer, Daniela Di Giuseppe, Merete Lund Hetland, Michael John Nissen, Gareth T. Jones, Bente Glintborg, Anne Gitte Loft, Johan Karlsson Wallman, Karel Pavelka, Jakub Závada, Ayten Yazici, Maria José Santos, Adrian Ciurea, Burkhard Möller, Brigitte Michelsen, Pawel Mielnik, Johanna Huhtakangas, Heikki Relas, Katja Perdan Pirkmajer, Ziga Rotar, Ross MacDonald, Bjorn Gudbjornsson, Irene van der Horst-Bruinsma, Marleen van de Sande, Myriam Riek

“…In the case of an unbiased CC approach, these two methods yielded representative samples of the distribution arising from a mixture of the original and modified composite scores, which, however, could not be considered the same as the distribution of the original score. …”
Get full text

Defining within-host SARS-CoV-2 RNA viral load kinetics during acute COVID-19 infection within different respiratory compartments and their respective associations with host infect... by Shirley Sze, Erol Gaillard, Manish Pareek, Iain Stephenson, Daniel Pan, Benjamin J Cowling, Laura Gray, Christopher A Martin, Caroline Williams, Mayuri Gogoi, Amani Al-Oraibi, Laura B Nellums, Joshua Nazareth, T. Déirdre Hollingsworth, Pip Divall, Michael Barer, Eve Fletcher, Natalia Grolmusova, Jonathan Decker, James Hay, Rebecca F. Baggaley, Anne L Wyllie, Tristan William Clark, Jonathan Nguyen Van-Tam

“…We seek to summarise existing data on the longitudinal RNA viral load kinetics of SARS-CoV-2 sampled from different parts of the respiratory tract (nose, nasopharynx, oropharynx, saliva and exhaled breath) and how this may vary with age, sex, ethnicity, immune status, disease severity, vaccination, treatment and virus variant.Methods and analysis We will conduct a systematic review and meta-analysis, using studies identified through MEDLINE and EMBASE (via Ovid). …”
Get full text

Plasma Proteomic Assessment of Calcific Aortic Valve Disease in Older Adults by Anna E. Bortnick, Thomas R. Austin, Emily Hamerton, Valborg Gudmundsdottir, Valur Emilsson, Lori L. Jennings, Vilmundur Gudnason, David S. Owens, Daniele Massera, Line Dufresne, Ta‐Yu Yang, James C. Engert, George Thanassoulis, Russell P. Tracy, Robert E. Gerszten, Bruce M. Psaty, Jorge R. Kizer

“…The potential causal associations of replicated proteins were tested in 2‐sample Mendelian randomization using identified cis protein quantitative trait loci in consortia having computed tomography‐quantified AVC or AS as outcomes. …”
Get full text

Impact of renin angiotensin system inhibitors on survival of patients with metastatic non-small cell lung cancer by Nadiye Sever, Emil Yunusov, Abdussamet Çelebi, Alper Yaşar, Nargiz Majidova, Erkam Kocaaslan, Pınar Erel, Yeşim Ağyol, Ali Kaan Güren, Selver Işık, Rukiye Arıkan, Özlem Ercelep, Osman Köstek, İbrahim Vedat Bayoğlu, Murat Sarıc

“…MAIN OUTCOMES AND MEASURES: Survival difference between mNSCLC patients with and without antihypertensive treatment. SAMPLE SIZE: 300 patients with mNSCLC RESULTS: Among patients receiving concomitant antihypertensive treatment, 107 (35.7%) were prescribed angiotensin-converting enzyme inhibitors (ACEi) or angiotensin II receptor blockers (ARB), 64 (21.3%) beta-blockers and 36 (11%) calcium channel blockers. …”
Get full text

Comprehensive integration of diagnostic biomarker analysis and immune cell infiltration features in sepsis via machine learning and bioinformatics techniques by Liuqing Yang, Liuqing Yang, Liuqing Yang, Rui Xuan, Rui Xuan, Rui Xuan, Dawei Xu, Dawei Xu, Dawei Xu, Aming Sang, Aming Sang, Aming Sang, Jing Zhang, Jing Zhang, Jing Zhang, Yanfang Zhang, Xujun Ye, Xinyi Li, Xinyi Li, Xinyi Li

“…Through docking analysis, we further validated the interaction between flavonoids and CD40LG. Lastly, blood samples were collected from healthy individuals and sepsis patients, with and without the administration of Xuebijing, for the extraction of peripheral blood mononuclear cells (PBMCs). …”
Get full text