The efficacy of total hip arthroplasty in patients with systemic lupus erythematosus: a systematic review and meta-analysis by Jun Lu, Jiangting Yu, Xiaoping Wang, Tingting Hua

“…Risk of bias was assessed using the Cochrane Risk of Bias tool for randomized trials and the Newcastle-Ottawa Scale for observational studies. …”
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Effects of Pomegranate Seed Oil on Lower Extremity Ischemia-Reperfusion Damage: Insights into Oxidative Stress, Inflammation, and Cell Death by Ümmü Gülşen Bozok, Aydan İremnur Ergörün, Ayşegül Küçük, Zeynep Yığman, Ali Doğan Dursun, Mustafa Arslan

“…<i>Materials and Methods</i>: The sample size was determined, then 32 rats were randomly allocated to four groups: Control (C), ischemia–reperfusion (IR), low-dose PSO (IR + LD, 0.15 mL/kg), and high-dose PSO (IR + HD, 0.30 mL/kg). …”
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The Effects of a Nursing Program Applying Zinc Oxide Mixed with Petroleum Jelly and Centella Asiatica Mixed with Aloe Vera on Skin Indicators Among Older Patients in Semi-Intensive... by Chaisomsee S, Banharak S, Sommana C, Tuntiyasawasdikul S, Sim-im S, Ransinyo K, Limpawattana P, Deesui W, Pimpun P, Somkamsri T, Seeharach O

“…However, further studies with larger sample sizes and more rigorous research designs are needed to validate these findings comprehensively. …”
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Effect of osteopathic manipulative treatment on comorbid depressive symptoms in patients with chronic low back pain: study protocol for a randomised controlled trial by Meike Shedden-Mora, Robert Schleip, Francesco Cerritelli, Tobias Schmidt, Lucas Bohlen, Michael Eggart, Bruno Müller-Oerlinghausen, Jürgen Lorenz, Torsten Liem, Jorge E Esteves

“…Participants will be randomly allocated (1:1 ratio) to receive six 45 min treatment sessions of either OMT (standard-OMT group) or sham treatment imitating OMT (sham-OMT group). …”
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Effect of community-based health insurance on the use of health service and perceived quality of care in Bacho Woreda, central Ethiopia: A mixed method study by Chala Damena Heyi, Anagaw Derseh, Berhan Tassew

“…Quantitative data was collected using a structured questionnaire among a randomly selected sample of 386 (126 member and 240 non-members) household heads. …”
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Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study. by Myrsini Kaforou, Victoria J Wright, Tolu Oni, Neil French, Suzanne T Anderson, Nonzwakazi Bangani, Claire M Banwell, Andrew J Brent, Amelia C Crampin, Hazel M Dockrell, Brian Eley, Robert S Heyderman, Martin L Hibberd, Florian Kern, Paul R Langford, Ling Ling, Marc Mendelson, Tom H Ottenhoff, Femia Zgambo, Robert J Wilkinson, Lachlan J Coin, Michael Levin

“…Individuals were randomized into training (80%) and test (20%) cohorts. …”
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Cross-cultural adaptation and validation of the Sinhala version of SarQoL® for assessing quality of life in older women with sarcopenia by Nirmala Rathnayake, Thilina Abeygunasekara, Gayani Liyanage, Sewwandi Subasinghe, Warsha De Zoysa, Dhammika Palangasinghe, Sarath Lekamwasam

“…The finalized Sinhala version of SarQoL® was administered to a randomly selected sample of 295 older women (≥ 65 years) who regularly attended medical clinics at a tertiary care hospital in Sri Lanka. …”
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Impact of probiotics on sleep quality and mood states in patients with insomnia: a systematic review and meta-analysis by Yi Liu, Yunfeng Yu, Shenghua Lu, Kang Tan, Pengfei Jiang, Pei Liu, Qinghua Peng, Qinghua Peng

“…This meta-analysis evaluated the effects of probiotics on sleep quality and mood in patients with insomnia.MethodsEight public databases were searched to identify relevant randomized controlled trials (RCTs) published before December 2024. …”
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Restorativeness mediates the effect of a brief virtual reality mindfulness exposure with a multi-ethnic group in a natural environment on global identity salience: a pilot study wi... by Claudia Russo, Luciano Romano, Davide Clemente, Alessia Congiu, Roberta Rodelli, Claudia Navarini, Angelo Panno

“…This study aimed to verify, in a sample of adolescents, the indirect effect of the exposure to a VR video of a group of multi-ethnic youths practicing a brief mindfulness session – compared to a VR video of a group of multi-ethnic youths involved in a volleyball play – on global identity through restorativeness.MethodsA quasi-experimental between-subjects design was adopted, involving 94 Italian adolescents randomly assigned to one of two conditions: (i) a 360-degree VR video showing a group of multi-ethnic youths practicing mindfulness in a natural environment or (ii) a 360-degree VR video showing a group of multi-ethnic youths playing volleyball in the same environment. …”
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Prevalence and characteristics of upfront diuretic resistance in acute heart failure: The P‐Value‐AHF study by Julia Baumberger, Sabine Dinges, Eleonora Lupi, Thomas Wolters, Melina Stüssi‐Helbling, Pietro E. Cippà, Antonio Bellasi, Lars C. Huber, Mattia Arrigo

“…Urine output was measured over the following 2 h and in patients with urine volume <300 mL, urine sodium concentration was additionally measured in a spot sample. Upfront diuretic resistance was defined as urine volume <300 mL in 2 h and urine sodium concentration <70 mmol/L. …”
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Effects of clear aligners treatment in growing patients: a systematic review by Vincenzo D’Antò, Vittoria De Simone, Silvia Caruso, Paolo Bucci, Rosa Valletta, Roberto Rongo, Rosaria Bucci

“…The “Risk of Bias 2” (RoB 2) and the “Risk of Bias in Non-randomized Studies of Interventions” (ROBINS-I) tools were applied to assess the methodological quality of the included studies. …”
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Melanoma Vaccines: Comparing Novel Adjuvant Treatments in High-Risk Patients by Joseph C. Broderick, Alexandra M. Adams, Elizabeth L. Barbera, Spencer Van Decar, Guy T. Clifton, George E. Peoples

“…Both trials had roughly equivalent sample sizes (<i>n</i> = 187 and <i>n</i> = 157, respectively) with similar demographics and disease characteristics. …”
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Efficacy of Levobupivacaine versus Ropivacaine for Tonsillar Pillar Block in Patients Undergoing Tonsillectomy: A Randomised Clinical Trial by Vishnu Sadanandan, Antony John Charles, Srinivasan Parthasarathy

“…All continuous variables were reported as mean and Standard Deviation (SD), while categorical variables were compared using the Chi-square test or Fisher’s-exact test with Yates correction, wherever necessary. Results: The sample comprised 30 patients in each group. The mean ages of the participants were 16.86 and 17.55 years, respectively. …”
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The Effect of Red Ginger Extract, Klanceng Honey, and Their Combination on Blood Sugar, Cholesterol, and Blood Viscosity of Patients With Diabetes Mellitus by Mardi Hartono, Sunarto Sunarto, Supriyo Supriyo, Sudirman Sudirman, Maslahtul Inayah

“…Further studies with larger sample sizes and longer treatment periods may be useful to obtain more precise results.…”
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Implementation and impact of mhealth in the management of diabetes mellitus in Africa: A systematic review and meta-analysis. by Franklin Okechukwu Dike, Jean Claude Mutabazi, Ezekiel Musa, Blessing Chinenye Ubani, Ahmed Sherif Isa, Chidiebele Malachy Ezeude, Henry Iheonye, Isah Idris Ainavi

“…Therefore, we recommend more well-designed randomized controlled trials to investigate the implementation and efficacy of mHealth in the management of diabetes mellitus in Africa.…”
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A New Computer-Based Cognitive Measure for Early Detection of Dementia Risk (Japan Cognitive Function Test): Validation Study by Hiroyuki Shimada, Takehiko Doi, Kota Tsutsumimoto, Keitaro Makino, Kenji Harada, Kouki Tomida, Masanori Morikawa, Hyuma Makizako

“…However, most studies have small sample sizes, with fewer than 100 individuals, and are based on case-control or cross-sectional designs. …”
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Career Development Programs and Employee Performance in Kanungu District, South Western Uganda by Ainebyona, Alex, Moses, Agaba

“…The study espoused a cross sectional research design. The study used a sample of 164 respondents who were both purposively and randomly selected. …”
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Metagenomic Insight into Cecal Microbiota Shifts in Broiler Chicks Following <i>Eimeria</i> spp. Vaccination by Dimitrios Marinos Karadedos, Tilemachos Mantzios, Despoina Eugenia Kiousi, Margaritis Tsifintaris, Ilias Giannenas, Panagiotis Sakkas, Georgios A. Papadopoulos, Gunther Antonissen, Aglaia Pappa, Alex Galanis, Vasilios Tsiouris

“…Performance parameters were recorded on a weekly basis, coccidiosis gross lesions in the intestine were evaluated on days 23 and 29, and microbiota samples were collected on day 23. Broilers in the challenged group exhibited significantly (<i>p</i> ≤ 0.05) increased coccidiosis gross lesions in the intestine at both sampling periods (7 and 19 days post-infection, dpi), whereas vaccination significantly (<i>p</i> ≤ 0.05) minimized the severity of lesions at both time points. …”
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Macroalgae Compound Characterizations and Their Effect on the Ruminal Microbiome in Supplemented Lambs by Adriana Guadalupe De la Cruz Gómez, Huitzimengari Campos-García, German D. Mendoza, Juan Carlos García-López, Gregorio Álvarez-Fuentes, Pedro A. Hernández-García, José Alejandro Roque Jiménez, Oswaldo Cifuentes-Lopez, Alejandro E Relling, Héctor A. Lee-Rangel

“…Results: The tagged 16S rRNA amplicon sequencing and statistical analysis revealed that the dominant ruminal bacteria shared by all four sample groups belonged to phyla <i>Firmicutes</i> and <i>Bacteroidota</i>. …”
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Evaluating the Therapeutic Efficacy of rTMS Combined with Low-Dose Antipsychotic Medication in Somatic Symptom Disorder by Wu J, Wang T, Jiang X

“…However, due to the small sample size of this study, further prospective, randomized controlled studies with larger samples are needed.Plain Language Summary: Given the limited efficacy of existing treatments for schizophrenia spectrum disorders (SSD), this study aimed to assess whether combining repetitive transcranial magnetic stimulation (rTMS) with low-dose antipsychotic medication could enhance therapeutic outcomes. …”
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