Oral supplementation of the nutraceutical decarboxy carcinine HCl for rhytids and skin rejuvenation by Célia Kalil, Luciane Zagonel, Valéria Barreto Campos, Christine Chaves Prato, Clarissa Reinehr, Patrícia França, Pedro Vargas

“…Further studies with larger sample sizes, extended follow-up periods, and advanced analytical methods are recommended to confirm these preliminary results.…”
Get full text

Shared genetic architecture between leukocyte telomere length and Alzheimer’s disease by Zhi Cao, Qilong Tan, Hongxi Yang, Chenjie Xu

“…We applied the bivariate causal mixture model (MiXeR) to calculate the number of shared genetic causal variants, and the conditional/conjunctional false discovery rate (condFDR/conjFDR) framework to identify specific shared loci between LTL and AD. Bidirectional two-sample Mendelian randomization (MR) were used to explore the causal associations between LTL and AD. …”
Get full text

Agro-physiological and transcriptome profiling reveal key genes associated with potato tuberization under different nitrogen regimes in aeroponics. by Rasna Zinta, Jagesh Kumar Tiwari, Tanuja Buckseth, Umesh Goutam, Rajesh Kumar Singh, Ajay Kumar Thakur, Vinod Kumar, Shwetank Singh, Manoj Kumar

“…Additionally, transcriptome analysis produced high-quality data ( ≥ Q20), ranging from 4.35 to 5.46 Gb per sample. Statistically significant genes (p ≤  0.05) were identified based on the reference potato genome. …”
Get full text

Determinants of acceptability of schistosomiasis mass drug administration among primary school children in Busega District, Northwestern Tanzania. by Irene Yunzu Edward, Patricia Maritim, Choolwe Jacobs, Adam Silumbwe, Hussein Mohamed, Joseph Mumba Zulu, Hikabasa Halwiindi

“…<h4>Results</h4>The study sample comprised 615 primary school children, 60.16% girls and 39.84% boys. …”
Get full text

Unlocking health insights: exploring intention to adopt district health information systems in Bahir Dar City, northwest Ethiopia by Habtamu Alganeh Guadie, Amarech Kindie, Hunegnaw Almaw Derseh, Desta Debalkie Atnafu

“…Model fitness was assessed using the Hosmer–Lemeshow goodness-of-fit test, with statistical significance set at a p-value &lt; 0.05 and a 95% confidence interval.ResultsA total of 342 participants completed the study, resulting in a response rate of 92.9%. The sample included 176 (51.5%) women, of whom 147 (43%) were nurses. …”
Get full text

Effects of a cognitive modulator in the theta and alpha asymmetry during a typewriting task: a sensorimotor integration perspective Efeitos de um modulador cognitivo na assimetria... by Marlo Cunha, Sergio Machado, Luiz Cláudio Miana, Dionis Machado, Victor Hugo Bastos, Bruna Velasques, Maurício Cagy, Luis F. Basile, Roberto Piedade, Pedro Ribeiro

“…This study aimed to elucidate cortical mechanisms and to identify the areas where occur such mechanisms due to interaction between bromazepam and motor learning. The sample was composed of 45 healthy subjects randomly distributed in 3 groups: placebo (n=15), bromazepam 3 mg (n=15) or bromazepam 6 mg (n=15). …”
Get full text

Participatory Action for Optimizing Health Literacy and Access to Manage Hypertension: Pre-post Evaluation in a Marginalized Community of India by Reetu Passi, Manmeet Kaur, Madhu Gupta, Savita Kumari, Rajesh Kumar

“…We measured changes in health literacy, HTN knowledge, risk factors, medication adherence, and HTN control in a sample of 510 randomly selected adults in pre and post-intervention design using chi-square and t -test. …”
Get full text

Client experiences of a task-shifting supported self-management intervention for depression in Vietnam by Leena W. Chau, Hayami Lou, Jill K. Murphy, Vu Cong Nguyen, Will Small, Hasina Samji, John O’Neil

“…Methods This paper is situated within a randomized controlled trial that demonstrated the effectiveness of the SSM intervention in adult populations across eight provinces in Vietnam. …”
Get full text

تحليل العلاقة بين الخداع الاستراتيجي والسلوك الانتهازي: دراسة استطلاعية لآراء عينة من العاملين في بعض الجامعة العراقية... by وائل حاتم ناصر

“…The relationship analysis between the Strategic Deception and Opportunistic Behavior: an exploratory study the opinions of a sample of workers in some Iraqi University Abstract The current study aims to acknowledge the type of the relationship between the Strategic deception, and Opportunistic behavior in the work. …”
Get full text

Using the socioecological model to explore factors associated with obesity among reproductive age women by Amanda Gilbert, Alicia Persaud, Sarah Farabi, Sarah Farabi, Cindy Schwarz, Debra Haire-Joshu, Rachel G. Tabak

“…Associations with interpersonal and environmental level factors were not statistically significant, which may be due to limited sample size or measures available to assess these levels. …”
Get full text

Clinical Profile and Outcomes of Central Microbial Keratitis in the Philippines by Ma. Dominga B. Padilla, MD, Ruben Lim Bon Siong, MD, George Michael N. Sosuan, MD

“…They underwent uniform sample collection and culture techniques as described in the ACSIKS. …”
Get full text

A cost-effectiveness analysis of two psychological treatments for controlled drinking in individuals with alcohol use disorder by Sergio Flores, Egill Jónsson-Bachmann, Stina Ingesson-Hammarberg, Anders Hammarberg, Camilla Nystrand, Filipa Sampaio

“…This model simulated a sample of patients with AUD over five years, calculating the costs and outcomes for both treatments. …”
Get full text

Aachen smoking cessation and harm reduction (ASCHR) trial study protocol – scientific evaluation of a psychological-telemedical counseling concept for smoking cessation in patients... by Sebastian Scheliga, Mara Derissen, Knut Kröger, Rainer Röhrig, Lea Schomacher, Hannah Schick, Rainer Beckers, Hinrich Böhner, Ute Habel

“…Anticipating a dropout rate of around 35%, the planned sample size is at least N = 1032 study participants. …”
Get full text

Miodynamic and Radiographic Evaluation in Recreative Athletes with Patellofemoral Pain by Abiel Eugenio Garza-Borjón, Mirna González-González, José Fernando de la Garza-Salazar, Mario Simental-Mendía, Carlos Acosta-Olivo

“…<i>Materials and Methods:</i> We conducted a prospective experimental study with a stratified, non-randomized, and non-blinded population sample with group matching, including an experimental group with PFP and a control group with no pain. …”
Get full text

The Relationship Between Orthodontic Malocclusion and Morphological Features of Sella Turcica Bridging and Ponticulus Posticus by Roberta Lekavičiūtė, Diana Šopagienė, Dainius Razukevičius, Giedrė Trakinienė, Kristina Lopatienė

“…<i>Materials and Methods</i>: The study sample consisted of 300 randomly selected pre-orthodontic treatment patients aged 7–40 years. …”
Get full text

Contrast-Enhanced CT-Based Radiomics Nomogram for Prediction of Pathologic T3a Upstaging in Clinical T1 RCC by Di Yin, Keruo Wang, Hongyi Xu, Yunfei Guo, Baoxin Qian, Dengyi Duan, Yiming Li, Wenyi Zhang, Zhengyang Li, Yang Zhao

“…<b>Methods</b>: A total of 169 cT1 patients with RCC with preoperative contrast-enhanced CT (CECT) and clinical data were enrolled in this study. Afterwards, the sample was split randomly into training and testing sets in a 7:3 ratio. …”
Get full text

Suboptimal Health Status and Stress: An Observational Study on Medical Students in Islamabad, Pakistan by Maryam Iqbal, Sumaira Masood, Manayal Arshad, Maryam Eman, Saad Ali, Maryam Ramzan, Omer Shafique, Ali Yar Ahmad, Amin Nauman

“…Methods: A total of 210 medical students were randomly selected. They were asked to fill in questionnaires. …”
Get full text

New Challenging Systemic Therapies for Juvenile Scleroderma: A Comprehensive Review by Chiara Sassetti, Claudia Borrelli, Martha Mazuy, Cristina Guerriero, Donato Rigante, Susanna Esposito

“…The overall evidence base is constrained by small sample sizes, a lack of controlled pediatric trials, and reliance on adult extrapolation. …”
Get full text

Therapeutic effects of olive leaf tea (Olea europaea L.) on gastrointestinal symptoms and body composition in adults with small intestinal bacterial overgrowth by Ayesha Zafar, Waqas Ahmed, Sajid Khan Tahir, Abdul Momin Rizwan Ahmad, Abdul Momin Rizwan Ahmad, Sanaullah Iqbal

“…The area under the curve, chi-square, independent, and paired sample t-tests were performed for data analysis.ResultsIn the intervention group, there was a significant decrease observed in GSRS score (from 19 to 6.8), symptomatic score (4.1 to 1.7), H2/CH4 peak (20.8–5.7 ppm), mean H2 (p = 0.0041) and mean H2 + CH4 production (p = 0.0043), with 88% GBT normalization rate (p = 0.001), as compared to the control group. …”
Get full text

Efficacy, safety, and immunogenicity of biosimilars compared with the biologic etanercept in patients with rheumatoid arthritis: a systematic review and meta-analysis by Aurélio Matos Andrade, Juliana da Motta Girardi, Erica Tatiane da Silva, Jakeline Ribeiro Barbosa, Daniella Cristina Rodrigues Pereira

“…Results This systematic review selected 6 eligible studies with a sample population of n = 2355. The main efficacy outcomes showed that both drugs did not present statistically significant differences in ACR20, ACR50, and ACR70 responses within 6 months (RR 1.00; 95% CI = 0.94 to 1.07; RR 1.09; 95% CI = 0.94 to 1.26; RR 1.04; 95% CI = 0.82 to 1.31, respectively), with I 2 ranging from 55 to 63% and 0.04 ≤ P ≥ 0.08. …”
Get full text