Three Weeks on a Ketogenic Diet Reduces Free Testosterone and Free Estradiol in Middle-Aged Obese Men and Women by Mads Svart, Nikolaj Rittig, Thien Vinh Luong, Nigopan Gopalasingam, Esben Thyssen Vestergaard, Lars Gormsen, Esben Søndergaard, Henrik Holm Thomsen, Claus H. Gravholt

“…This investigation integrated samples from two distinct studies. Study I was a randomized, controlled, crossover trial with ten healthy, young male participants receiving either a weight-adjusted ketone ester or control (water, CTR) and vice versa following an overnight fast. …”
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Emerging threat of artemisinin partial resistance markers (pfk13 mutations) in Plasmodium falciparum parasite populations in multiple geographical locations in high transmission re... by Bosco B. Agaba, Jye Travis, David Smith, Simon P. Rugera, Maria G. Zalwango, Jimmy Opigo, Charles Katureebe, Ruth Mpirirwe, Dembo Bakary, Martin Antonio, Beshir Khalid, Joseph Ngonzi, Moses R. Kamya, Pontiano Kaleebu, Peter Piot, Qin Cheng

“…Three mutations were identified within the sequenced samples; pfk13 C469Y in 32/238 (13.5%) samples, pfk13 A675V in 14/238 (5.9%) and pfk13 S522C in (1/238 (0.42%) samples across the four surveyed regions. …”
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Assess, Prevent, and Manage Pain; Both Spontaneous Awakening and Breathing Trials; Choice of Analgesia/Sedation; Delirium: Assess, Prevent, and Manage; Early Mobility; Family Engag... by Alvin D. Jeffery, PhD, RN, CCRN-K, NPD-BC, FNP-BC, Jennifer A. Werthman, PhD, RN, Valerie Danesh, PhD, RN, Mary S. Dietrich, PhD, Lorraine C. Mion, PhD, RN, Leanne M. Boehm, PhD, RN, ACNS-BC, FCCM

“…This multicenter, exploratory, cross-sectional study used data from two ICU-based randomized controlled trials that measured daily bundle adherence. …”
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Prevalence and determinants of incomplete or not at all vaccination among children aged 12–36 months in Dabat and Gondar districts, northwest of Ethiopia: findings from the primary... by Tadesse Awoke Ayele, Kassahun Alemu, Haileab Fekadu Wolde, Destaw Fetene Teshome, Asmamaw Atnafu, Gashaw Andargie, Mezgebu Yitayal, Getu Debalkie Demissie, Endalkachew Dellie, Telake Azale, Bisrat Misganaw Geremew, Adane Kebede, Tsegaye Gebremedhin, Terefe Derso

“…Thus, this study aimed to assess the prevalence and determinants of incomplete or not at all vaccination among children aged 12–36 months in Dabat and Gondar districts, Northwest Ethiopia.Study design The study is community-based cross-sectional study.Study setting Dabat and Gondar Zuria districts, Northwest Ethiopia.Participants Mothers/caregivers with children aged 12–36 months were enrolled in the study. Participants were randomly selected through systematic sampling and a total of 603 participants were included in the analysis.Methods A binary logistic regression analysis was done. …”
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Efficacy of Intermittent Fasting in the Management of Chronic Plaque Psoriasis: A Phase IIb Clinical Trial by Shekhar Neema, Biju Vausdevan, Pratibha Misra, Senkadhir Vendhan, MK Sibin, Seema Patrikar

“…Limitations: The small sample size and loss to follow-up are major limitations of the study. …”
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Tuberculosis preventive therapy for people living with HIV: A systematic review and network meta-analysis. by Mercedes Yanes-Lane, Edgar Ortiz-Brizuela, Jonathon R Campbell, Andrea Benedetti, Gavin Churchyard, Olivia Oxlade, Dick Menzies

“…Of these, 20 studies (reporting 16 randomized trials) were included. The median sample size was 616 (interquartile range [IQR], 317 to 1,892). …”
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Microscopic and Molecular Identification of <i>Eimeria</i> Species in Domestic Rabbits (<i>Oryctolagus cuniculus</i>) in Romania by Beatrice Ana-Maria Jitea (Sîrbu), Sorin Morariu, Mirela Imre, Tiana Florea, Cătălin Bogdan Sîrbu, Iasmina Luca, Simona Dumitru, Gheorghe Dărăbuș

“…The samples were collected from rabbits raised in individual household settings, under various management systems—both in individual cages and in common ground-based enclosures. …”
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Development of a SNP Panel for Geographic Assignment and Population Monitoring of Jaguars (Panthera onca) by Gabriele Zenato Lazzari, Henrique Vieira Figueiró, Caroline Charão Sartor, Emiliano Donadio, Sebastián Di Martino, Hope M. Draheim, Eduardo Eizirik

“…We used whole‐genome data from an additional 18 jaguars to further test these panels, which provided insights into kinship relationships and allowed inference of geographic origin of samples collected outside the spatial scope of the original sample set. …”
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Unveiling causal relationship between white matter tracts and psychiatric disorders by Yifan Yu, Tianye Jia, Xiao Lin, Yanping Bao, Suhua Chang, Jie Sun, Teng Gao, Jie Shi, Sizhi Ai, Kai Yuan

“…Thus, we employed two-sample bidirectional Mendelian randomization to explore the causality between WMTs and 10 psychiatric disorders. …”
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A Black Sticky Rice-Derived Functional Ingredient Improves Anxiety, Depression, and Stress Perception in Adult Volunteers by Pattamaporn Natthee, Jintanaporn Wattanathorn, Wipawee Thukham-mee, Pongsatorn Paholpak, Poonsri Rangseekajee, Nawanant Piyavhatkul, Suphayanakorn Wattanathorn, Supaporn Muchimapura, Terdthai Tong-Un

“…Our results show that the novel functional ingredient can improve anxiety, depression, and stress perception partly by decreasing oxidative stress and inflammation; however, randomized, double-blind, placebo-controlled studies with a larger sample size should be performed to confirm this benefit.…”
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Socio-demographic correlates of health behaviors of children and adolescents during the COVID-19 pandemic: a cross-sectional study by Viviane Richard, Elsa Lorthe, Roxane Dumont, Andrea Loizeau, Hélène Baysson, María-Eugenia Zaballa, Julien Lamour, Rémy P. Barbe, Klara M. Posfay-Barbe, Idris Guessous, Silvia Stringhini, SEROCoV-KIDS study group

“…Abstract This study aimed to assess the socio-demographic correlates of health behaviors and their changes during the COVID-19 pandemic. A population-based sample of children (3–17 years) was randomly selected between 12/2021 and 06/2022 in Geneva, Switzerland. …”
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Dopamine receptor DRD1 expression (mRNA, protein level) in peripheral blood lymphocytes and prognosis of antipsychotic therapy by A. M. Zabotina, A. S. Zhuravlev, M. N. Grunina, R. F. Nasyrova, E. V. Volkova, A. A. Tyurin, O. V. Limankin, A. P. Otmakhov, E. M. Krupitsky, N. G. Neznanov, A. E. Taraskina

“…Peripheral blood lymphocytes (PBL) are the research object of neurotransmission receptors.The objective was to study DRD1 gene expression (mRNA, protein level) in PBL as a possible biomarker of olanzapine and haloperidol therapy prognosis.Methods and Materials. Sample: 106 patients diagnosed with schizophrenic spectrum disorder. …”
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The Impact of Reich’s Vegetotherapy on Emotional Regulation and Postural Balance in Military Personnel: A Non-Pharmacological Approach to Combat Stress by Sana Khadhrani, Imed Touhemi, Amri Hammami, Chiraz Goumni, Jihen Khalfoun, Mohanad Omar, Rebai Haithem, Abderraouf Ben Abderrahman

“…Further research with larger sample sizes is necessary to validate these results and explore its broader applications.…”
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Luteolin attenuates inflammation and apoptosis in LPS-induced ALI mice by activating the HGF/c-Met pathway by Jihong Bi, Yan Li, Lin Lu, Tingting Yin, Shaohua Mao, Run Zhang, Juan He, Xing Ni, Kai Wang, Jirui Bi

“…ObjectiveTo investigate the protective effects of luteolin on ALI induced by lipopolysaccharide (LPS) in male mice and to explore the underlying mechanisms.MethodsA two-sample Mendelian randomization (MR) analysis was conducted to assess the causal relationship between hepatocyte growth factor (HGF) and acute respiratory distress syndrome (ARDS). …”
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An online vignette experiment on stigma and help-seeking attitudes towards five mental health problems in adolescents and emerging adults by Diana Lemmer, Markus Moessner, Nicolas Arnaud, Harald Baumeister, Agnes Mutter, Sarah-Lena Klemm, Elisa König, Paul Plener, Christine Rummel-Kluge, Rainer Thomasius, Michael Kaess, Stephanie Bauer

“…BN elicited more blame than DEP, whereas the reverse pattern emerged for distrust. However, this sample generally held positive MH attitudes. The results highlight the importance of addressing disorder-specific stigma and may inform the development of targeted anti-stigma and help-seeking campaigns. …”
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The Effect of Dialysate Bicarbonate Concentration or Oral Bicarbonate Supplementation on Outcomes in Patients on Maintenance Dialysis: A Systematic Review and Meta-Analysis by Ashlee M. Azizudin, Samuel A. Silver, Amit X. Garg, Zoe K. Friedman, Andrea C. Cowan, Catherine M. Clase, Amber O. Molnar

“…Most studies reporting nutritional outcomes (n = 21) reported no significant differences with dialysate bicarbonate concentration or oral bicarbonate supplementation but were small in sample size (largest study n = 200). Meta-analysis of parallel-group randomized trials comparing dialysate bicarbonate >35 mmol/L with ≤35 mmol/L found a mean difference of 3.5 mmol/L (95% confidence interval [CI] −0.6 to 7.7) in pre-dialysis serum bicarbonate. …”
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Prevalence of chronic obstructive pulmonary disease in high-risk populations at low, intermediate, high altitudes: a population based cross-sectional study in Yunnan Province, Chin... by Geyi Wen, Jinliang Meng, Huadan Wang, Puxian Peng, Yanyan Xu, Ruiqi Wang, Zhengmao Yan, Bangyan Du, Aihan Wen, Guohong Luo, Wenlong Cui, Songyuan Tang, Yunhui Zhang

“…Methods This cross-sectional study employed a multi-stage randomized cluster sampling method and enrolled 11,095 adult residents aged ≥ 20 years at different elevations in Yunnan Province, China. …”
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Nitrous oxide prediction through machine learning and field-based experimentation: A novel strategy for data-driven insights by Muhammad Hassan, Khabat Khosravi, Travis J. Esau, Gurjit S. Randhawa, Aitazaz A. Farooque, Seyyed Ebrahim Hashemi Garmdareh, Yulin Hu, Nauman Yaqoob, Asad T. Jappa

“…The dataset comprised 401 samples from potato fields in Prince Edward Island (PEI) and 122 samples from New Brunswick (NB), including measurements of N2O and H2O and related input variables such as soil moisture (SM), temperature ST, electrical conductivity (EC), wind speed, solar radiation, relative humidity, precipitation, air temperature (AT), dew point, vapor pressure deficit, and reference evapotranspiration. …”
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FTIR-based molecular fingerprinting for the rapid classification of dengue and chikungunya from human sera using machine learning: an observational studyResearch in context by Souvik Das, Subhanita Roy, Aritri Bir, Arindam Ghosh, Tarun Kanti Bhattacharyya, Pooja Lahiri, Basudev Lahiri

“…Additionally, t-SNE and Silhouette analyses demonstrated superior clustering performance with FTIR, with clear separation of Chikungunya samples (average Silhouette score 0.385) compared to Raman, where clustering was less distinct. …”
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Integrated single-cell and transcriptomic analysis of bone marrow-derived metastatic neuroblastoma reveals molecular mechanisms of metabolic reprogramming by Jing Chu, Rong Qin, Shu-Jing Wang, Qiang Wang, Qiang Wu

“…Single-cell transcriptomic analysis of bone marrow–derived NB samples identified nine distinct cell subpopulations with diverse intercellular communication networks. …”
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