Artificial intelligence-based radiogenomics reveals the potential immunoregulatory role of COL22A1 in glioma and its induced autoimmune encephalitis by Bingchao Yan, Bingchao Yan, Qian Chen, Dacheng Wang, Leili Ding, Leili Ding, Jingfeng Qu, Renfei Du, Renfei Du, Wenjie Shi, Ulf D. Kahlert, Zhengquan Yu

“…Gene expression was validated by immunohistochemistry using our clinical samples. Immune infiltration was evaluated using five algorithms (MCP-counter, EPIC, TIMER, QUANT and IPS). …”
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Electronic cigarette use in relation to changes in smoking status and respiratory symptoms by Linnéa Hedman<sup>+<sup>, Gustaf Lyytinen<sup>+<sup>, Helena Backman, Magnus Lundbäck, Caroline Stridsman, Anne Lindberg, Hannu Kankaanranta, Lina Rönnebjerg, Eva Rönmark, Linda Ekerljung

“…Methods A prospective, population-based study of random samples of the population (age 16–69 years) was performed within The Obstructive Lung Disease in Northern Sweden (OLIN) study and West Sweden Asthma Study (WSAS). …”
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Identification and validation of expression and functions of ferroptosis-related gene HILPDA in early-onset preeclampsia placentas by Qianghua Wang, Xuegu Wang, Jiaojiao Fei, Chuanyue Jiang, Yafen Tao, Nana Yang, Huijuan Chen, Chengli Dou, Biao Ding, Danli Du, Xiang Li

“…Experimental validation included Western blot on clinical placental samples and siRNA-mediated knockdown in HTR-8/SVneo trophoblasts to assess migration.ResultsWe observed HILPDA upregulation and confirmed its diagnostic accuracy (AUC=0.71) in EOPE placentas. …”
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Tanshinone Content Prediction and Geographical Origin Classification of <i>Salvia miltiorrhiza</i> by Combining Hyperspectral Imaging with Chemometrics by Yaoyao Dai, Binbin Yan, Feng Xiong, Ruibin Bai, Siman Wang, Lanping Guo, Jian Yang

“…Partial least squares discriminant analysis (PLS-DA) and support vector machine (SVM) models were employed to discriminate 420 <i>Salvia miltiorrhiza</i> samples collected from Shandong, Hebei, Shanxi, Sichuan, and Anhui Provinces. …”
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Prevalence and genotyping of Enterocytozoon bieneusi in cattle from Shanxi and Inner Mongolia, China by Wen-Jun Fan, Shan Zhang, Li-Feng Wang, Yu-Lin Ding, Hai-Xia Liu, Ming-Yuan Wang, Yan Wang, Hai-Liang Chai, Zhan-Sheng Zhang, Chao Yi, Wen-Xiong Han, Xuewen Su, Li Zhao, Yong-Hong Liu

“…In this study, the internal transcribed spacer (ITS) gene of E. bieniusi was assessed. Fecal samples (n = 1338) were randomly collected from 15 intensive and free-range cattle farms in Northern Shanxi and Central Inner Mongolia between 2021 and 2022. …”
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UNIPDES - An internet-based transdiagnostic intervention for college students’ psychological symptoms: Evaluation of its development, usability and effectiveness: Study protocol by Ömer Özer, Gizem Öztemür, Ali Ercan Altinöz, Burak Köksal, Uğur Doğan, Sedat Batmaz, Recep Gür, Ahmet Altinok

“…Participants will be randomly assigned to either guided, unguided, or control groups. …”
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Connaissances, attitudes et pratiques des prescripteurs sur l’antibiothérapie et la résistance aux antibiotiques dans la région de la Kara au Togo en 2024 by Séwa Kokou, Mébiny-Essoh Agballa Tchalla Abalo, Rébecca Kinde, Somiabalo Payakissim Atèkpè, Abalo Mazamesso Palanga, Bassotom Lakougnon, Ditorguéna Bassokla Wasungu, Lawaratou Okotan, Zakariaou Bouraïma, Nounguéboame Douti, Kossi Kamékpo, Mabinou Yékplé, Améto Adzo Kogbetsè, Kamaloudine Kpékpassi, Léname Bounti, Barema Redah, Koudjo Elom Adanlekponsi, Mawaba Peleke Hilim, Akawulu N’Djao, Dzidzova Amenyido Nyameko, Yenduban Douti, Aboudramane Lambonkale, Koffi Akolly, Monfaye Sabi, Sibabe Agoro, Koumavi Didier Ekouevi

“…It included 451 healthcare workers from three levels of care selected by simple random sampling from a database of 833 prescribers in the region. …”
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Advice on better utilization of validation data to adjust odds ratios for differential exposure misclassification (recall bias) by Igor Burstyn, George Luta

“…that probabilistic bias analysis should be carried out to account simultaneously for uncertainty in misclassification probabilities and random sampling errors (3). When this is done, probabilistic bias analysis does not guarantee the correction or adjustment for misclassification of exposure, but it merely produces a collection of alternative estimates via a Monte-Carlo simulation. …”
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Creating Chemiluminescence Signature Arrays Coupled with Machine Learning for Alzheimer’s Disease Serum Diagnosis by Biyue Zhu, Yanbo Li, Shi Kuang, Huizhe Wang, Astra Yu, Jing Zhang, Jun Yang, Johnson Wang, Shiqian Shen, Xuan Zhai, Jiajun Xie, Chongzhao Ran

“…Inspired by the bat echolocation mechanism, we propose an “echoes” approach for creating chemiluminescence signatures via screening of a compound library, and serum samples of Alzheimer’s disease (AD) were used for our proof-of-concept study. …”
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The effects of nutrition education with Pecha Kucha method on prevention of malnutrition in cancer patients undergoing radiotherapy: a randomised controlled study by Gülcan Bahcecioglu Turan, Fatma Karaaslan, Zülfünaz Özer

“…These patients were randomly assigned to either the experimental group (n = 30) or the control group (n = 30). …”
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The role of psychosocial factors in the interprofessional management of women with chronic pelvic pain: A systematic review by Susanne G. R. Klotz, Clarissa Kolbe, Miriam Rueß, Christian A. Brünahl

“…Only one study used a randomized controlled design, the other study used a non‐randomized controlled group. …”
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Use of Viremia to Evaluate the Baseline Case Fatality Ratio of Ebola Virus Disease and Inform Treatment Studies: A Retrospective Cohort Study. by Oumar Faye, Alessio Andronico, Ousmane Faye, Henrik Salje, Pierre-Yves Boëlle, N'Faly Magassouba, Elhadj Ibrahima Bah, Lamine Koivogui, Boubacar Diallo, Alpha Amadou Diallo, Sakoba Keita, Mandy Kader Konde, Robert Fowler, Gamou Fall, Simon Cauchemez, Amadou Alpha Sall

“…This study provides baseline CFRs by viremia group, which allow appropriate adjustment when estimating efficacy in treatment studies. In randomized controlled trials, stratifying analysis on viremia groups could reduce sample size requirements by 25%. …”
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Evaluating the necessity of booster sessions in relapse prevention for depression: a longitudinal study by Jón Ingi Hlynsson, Jón Ingi Hlynsson, Tómas Kristjánsson, Gerhard Andersson, Gerhard Andersson, Gerhard Andersson, Per Carlbring, Per Carlbring, the ACTUA research group

“…This study therefore evaluated the long-term effectiveness of relapse prevention treatment booster sessions for major depression.MethodIn a two-arm, parallel-group, maintenance-phase randomized controlled trial (RCT) with repeated longitudinal measures, the sample consisted of participants in Sweden who had received acute treatment for depression (internet-based behavioral activation or physical activity) and were then randomly assigned to either an 8-week relapse prevention program (n = 119) or control group (n = 143). …”
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Efficacy and safety of eszopiclone combined with drug therapy in the treatment of insomnia after stroke: A network meta-analysis and systematic review. by Ruo-Yang Li, De-Liang Zhu, Ke-Yu Chen

“…In the future, more multicentre, large sample, double-blind randomized controlled trials are needed to supplement and demonstrate the results of this study.…”
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Optimizing Endodontic Surgery: A Systematic Review of Guided Tissue Regeneration, Grafting, and Platelet Concentrates vs. No Intervention by Mohammad Sabeti, Natalie Black, Mohsen Ramazani, Nafiseh Zarenejaddivkolahei, Mahmood Moosazadeh

“…However, more research will be needed with larger sample sizes and longer follow-up times.…”
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Screening Mammography for Young Women in Israel: Between Guidelines and Common Practice by Neta Essar Schvartz, Michal Rotem-Green, Dikla Kruger, Anat Gaver, Inbar Safra, Danielle Mira Harari, Nadav Niego, Mordechai Alperin

“…Findings In this cross-sectional study of a randomly selected sample of 1,287 referral letters, given to women aged 18 to 50 y, only 10.9% were adherent with the guidelines when examined with a strict approach and 30.6% with a forgiving approach. …”
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Association between housing status and mental health and substance use severity among individuals with opioid use disorder and co-occurring depression and/or PTSD by Lauren Kelly, Grace M. Hindmarch, Katherine E. Watkins, Colleen M. McCullough, Beth Ann Griffin, Lisa S. Meredith, Sapna Mendon-Plasek, Miriam Komaromy, Sarah B. Hunter

“…Results Among the 797 patients randomized, 13% of the sample was currently unhoused, 24% was unstably housed, and 63% was stably housed. …”
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Effect of feedback-integrated reflection, on deep learning of undergraduate medical students in a clinical setting by Zainab Maqsood, Madiha Sajjad, Raheela Yasmin

“…Objective To evaluate the impact of feedback-integrated reflection versus reflection alone on higher-order MCQ scores among undergraduate medical students in a gynecology clinical setting. Methods A randomized controlled trial was conducted with 68 final-year medical students randomly assigned to a study group (feedback-integrated reflection) and a control group (reflection alone). …”
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Validation of the Global Scales of Early Development (GSED) tool in rural Western Kenya by Joshua Jeong, Juliet K. McCann, Silas Onyango, Michael Ochieng

“…The GSED-LF was administered to all children (N = 647). In a randomly selected sub-sample of children (N = 116), the Bayley Scales of Infant and Toddler Development (Bayley-III) and the Caregiver Reported Early Development Instruments (CREDI) were also administered to compare their scores with those from the GSED-LF. …”
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From gaps to guidelines: a process for providing guidance to bridge evidence gaps by Olga Yaroslavtseva, Judith Gargaro, Eleni M. Patsakos, Aishwarya Nair, Robert Teasell, Mark T. Bayley

“…Randomized controlled trials in this field often have limitations, such as smaller sample sizes and gender and racial disparities in enrollment, that reduce the level of evidence they can provide. …”
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