A study on the pharmacokinetic bioequivalence of oral tablet formulations of riluzole among healthy volunteers utilizing HPLC-MS/MS by Fei Yu, Rui Wang, Keli Wang, BoYang Lin, Xuan Zhou, Linghong Chen, Li Ma, Zheng Liao, Wanggang Zhang

“…Venous blood samples (4 mL) were collected 22 times from each subject, starting before dosing (0 h) and ending 48 h after. …”
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An Integrated Study of Ramie (Boehmeria nivea), and Its Wild, Cultivated, and Feral Forms by Ying Zhao, Richard I. Milne, Jie Liu, Zhi‐Peng Li, Xiao‐Gang Fu, Ke Li, Amos Kipkoech, Zeng‐Yuan Wu

“…Here, 78 wild and feral individuals were sampled from 12 Chinese provinces, plus 11 cultivated individuals from farmland. …”
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A Comprehensive Study of Spatial Distribution, Pollution Risk Assessment, and Source Apportionment of Topsoil Heavy Metals and Arsenic by Honghua Chen, Xinxin Sun, Longhui Sun, Yunce An, Ying Xiao, Jintao Zhang, Yunpeng Hong, Xiaodong Song

“…Finally, source apportionment was conducted using random forest (RF), absolute principal component score–multiple linear regression (APCS-MLR), correlation analysis, and spatial distribution of soil HMs and As. …”
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Sero-epidemiological survey of Coxiella burnetii in livestock and humans in Tana River and Garissa counties in Kenya. by Damaris Mwololo, Daniel Nthiwa, Philip Kitala, Tequiero Abuom, Martin Wainaina, Salome Kairu-Wanyoike, Johanna F Lindahl, Enoch Ontiri, Salome Bukachi, Ian Njeru, Joan Karanja, Rosemary Sang, Delia Grace, Bernard Bett

“…<h4>Methods</h4>Data were collected through a cross-sectional study. Serum samples were taken from 2,727 animals (466 cattle, 1,333 goats, and 928 sheep) and 974 humans and screened for Phase I/II IgG antibodies against C. burnetii using enzyme-linked immunosorbent assay (ELISA). …”
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Osteopontin as a diagnostic and NTZ-response biomarker of multiple sclerosis: a systematic review and meta-analysis by Adela González-Jiménez, Adela González-Jiménez, Elena Urcelay, Elena Urcelay, Laura Espino-Paisán, Laura Espino-Paisán

“…This article presents a systematic review and meta-analysis of the association between OPN levels in CSF and blood and the presence of MS.MethodsWe searched PubMed, Embase, and Cochrane databases for articles measuring OPN concentrations in peripheral blood and CSF samples from MS patients, published before July 12, 2024. …”
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ATTITUDES, PREFERENCES, AND CHARACTERISTICS OF OHIO'S SPRING TURKEY HUNTERS, 1985–2001 by David A. Swanson, Robert J. Stoll Jr., W. Lloyd Culbertson

“…As hunter numbers increased, so have problems and issues with managing the spring hunt. Random samples of Ohio spring turkey hunters were mailed a questionnaire immediately following the 1985, 1989, 1996, and 2001 spring turkey seasons. …”
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Preliminary analysis of salivary microbiota in catathrenia (nocturnal groaning) using machine learning algorithms by Min Yu, Yujia Lu, Wanxin Zhang, Xu Gong, Zeliang Hao, Liyue Xu, Yongfei Wen, Xiaosong Dong, Fang Han, Xuemei Gao

“…Ten patients (6 M/4 F) underwent post-treatment PSG. Salivary samples were collected, and microbial characteristics were analyzed using 16S rRNA gene sequencing. …”
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Microbiome characteristics associated with lymph node metastasis in laryngeal squamous cell carcinoma by Fangxu Yan, Shibo Chen, Xin Xia, Yue Fan, Shuting Yu, Xiao Zhang, Xingming Chen

“…Based on repeated stratified 3 cross-validation, random forest models were used to identify metastasis-associated genera. …”
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Influence of Rice–Crayfish Co-Culture Systems on Soil Properties and Microbial Communities in Paddy Fields by Dingyu Duan, Dingxuan He, Liangjie Zhao, Chenxi Tan, Donghui Yang, Wende Yan, Guangjun Wang, Xiaoyong Chen

“…Soil and water samples were collected post-harvest and pre-transplanting to assess soil properties, extracellular enzyme activity, and microbial community structure. …”
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An ensemble strategy for piRNA identification through hybrid moment-based feature modeling by Mansoor Ahmed Rasheed, Tamim Alkhalifah, Fahad Alturise, Yaser Daanial Khan

“…Use of independent set testing accross species evaluates the generalizability and adaptability of the model for diverse data samples. The proposed method TranspoRed achieved exquisite results on diverse datasets for humans, mouse and Drosophila. …”
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Examining acquired brain injury-associated symptoms and fluid-based biomarkers in females surviving intimate partner violence: An observational pilot study protocol by Michelle Patch, Allison Jacobi-Dorbeck, Tamar Rodney, Gabor Kelen, Jacquelyn C Campbell, Leah H Rubin, Chelsea Wagner, Nancy Perrin, Jessica Gill

“…Analyses will include random effects regression, product moment correlations, and descriptive statistics. …”
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Research on High-Accuracy, Lightweight, Superfast Model for Nitrogen Diagnosis and Plant Growth in Lettuce (<i>Lactuca sativa</i> L.) by Xuyang Li, Iftikhar Hussain Shah, Xiaohao Gong, Muhammad Azam, Wu Jinhui, Pengli Li, Yidong Zhang, Qingliang Niu, Liying Chang

“…Traditional methods for nitrogen diagnosis in lettuce, such as laboratory-based analysis of plant samples, are labor-intensive, time-consuming, and lack real-time monitoring capabilities. …”
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A new risk assessment model of venous thromboembolism by considering fuzzy population by Xin Wang, Yu-Qing Yang, Xin-Yu Hong, Si-Hua Liu, Jian-Chu Li, Ting Chen, Ju-Hong Shi

“…Adjusting the distribution of negative samples in the training set based on the ‘fuzzy population’ would exacerbate the instability of performance of five ML models, which limited the application of ML methods in clinic. …”
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Remotely sensed spectral indicators of bird taxonomic, functional and phylogenetic diversity across Afrotropical urban and non-urban habitats by Adewale G. Awoyemi, Tunrayo R. Alabi, Juan Diego Ibáñez-Álamo

“…Random Forest Regressions and Generalized Linear Mixed Effect Models were used to identify the topmost ranked indicator of each avian diversity component, and its variation between urban and non-urban areas. …”
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Anoikis in prostate cancer bone metastasis gene signatures and therapeutic implications by Wei Xia, Miao Ye, Bo Jiang, Gang Xu, Guancheng Xiao, Qingming Zeng, Ruohui Huang

“…Specific anoikis-related genes (ARGs) were identified, and Random Survival Forest analysis and multivariate Cox regression were employed to develop anoikis-linked features. …”
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Efficaciousness of dexmedetomidine in children undergoing cleft lip and palate repair: a systematic review and meta-analysis by Li Pan, Jiale Quan, Chunwei Lian, Dengfeng Liu, Yin Gao, Jiefan Liu, Xiangwei Li, Congcong Huang

“…However, further verification with larger samples and higher-quality RCTs is needed.…”
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Machine learning combined multi-omics analysis to explore key oxidative stress features in systemic lupus erythematosus by Hongwei Zhou, Xiaoqing Li, Yanyu Zhang, Feng Wei, Zhiyu Liu, Yan Zhao, Xubo Zhuang, Xia Liu, Haizhou Zhou

“…Peripheral blood plasma samples from confirmed SLE patients and healthy controls (HC) were analyzed using liquid chromatography-mass spectrometry (LC-MS) for metabolomics profiling and to evaluate OS and antioxidant stress (AOS) levels. …”
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Tryptophan metabolites profile predict remission with dietary therapy in pediatric Crohn’s disease by Rotem Sigall Boneh, Nikki van der Kruk, Eytan Wine, Charlotte M. Verburgt, Tim G. J. de Meij, Mark Löwenberg, Krisztina B. Gecse, Nicolette Wierdsma, Joep P. M. Derikx, Wouter J. de Jonge, Geert D’Haens, Mohammed Ghiboub, Johan E. Van Limbergen

“…We performed a targeted quantitative analysis of 21 tryptophan-metabolites in baseline ( t  = 0) fecal samples from both groups, utilizing liquid chromatography coupled with quadrupole mass spectrometry. …”
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The influence of rhizosphere soil microorganisms and environmental factors on gentiopicroside content in the roots and rhizomes of Gentiana scabra Bunge from Liaoning Province by Jianming Hou, Haibo Yin, Haibo Yin, Dan Wang, Jiayi Luo, Wenqi Yang, Tingguo Kang

“…Through high-throughput sequencing technology, and with the help of PLS-DA and RDA, the impacts of rhizosphere soil microorganisms and environmental factors on the quality of G. scabra were explored in depth.ResultsAlpha diversity shows that the diversity of bacterial communities varies significantly, while the regularity of fungi is weak; beta diversity shows that samples from different producing areas can be effectively grouped according to community structure. …”
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Machine learning-based prediction of adverse pregnancy outcomes in antiphospholipid syndrome using pregnancy antibody levels by Wanqing Liu, Ju Huang, Jun Xiao, Shanling Yan

“…Six machine learning models were developed: Light Gradient Boosting Machine (LGBM), CatBoost, Extreme Gradient Boosting (XGBoost), Logistic Regression (LR), Random Forest (RF), and Multi-Layer Perceptron (MLP). …”
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