Meta-analysis of the efficacy of applying reduced surgery for the treatment of asymptomatic unresectable advanced gastric cancer by Xiong Li, Ting Lei, Liangyin Fu, Ruiyu Gao, Ning Cao, Yuanhui Gu, He Su, Tiankang Guo, Yang Che

“…The cumulative sample size was 1717 cases, including 701 cases in the reduced surgery group and 1016 cases in the non-surgical treatment group. …”
Get full text

Anemia Associated with Student Learning Achievement: Cross-Sectional Study by Taqwin Taqwin, Eka Purwita sari, Asrawati Asrawati, Hadriani Hadriani, Henrietta Imelda Tondong, Siti Hadijah Batjo, Sri Yanti Kusika, Niluh Nita Silfia

“…Methods: The type of research was a cross-sectional study conducted in June 2022 at one of the Aliyah madrasas in Palu City. Research samples from 34 adolescent girls were taken using a simple random technique. …”
Get full text

Identification and Validation of Four Serum Biomarkers With Optimal Diagnostic and Prognostic Potential for Gastric Cancer Based on Machine Learning Algorithms by Yi Liu, Bingxian Bian, Shiyu Chen, Bingqian Zhou, Peng Zhang, Lisong Shen, Hui Chen

“…These findings were then validated through the receiver operating characteristic (ROC) curve and Kaplan–Meier analysis, and were experimentally confirmed in GC samples by reverse transcription–polymerase chain reaction (RT‐PCR) and enzyme‐linked immunosorbent assay (ELISA). …”
Get full text

Trade-Offs of Plant Biomass by Precipitation Regulation Across the Sanjiangyuan Region of Qinghai–Tibet Plateau by Mingxue Xiang, Gang Fu, Junxi Wu, Yunqiao Ma, Tao Ma, Kai Zheng, Zhaoqi Wang, Xinquan Zhao

“…During the 2024 growing season, a total of 63 sites (including 189 plots and 945 quadrats) were sampled along five aridity classes: <400, 400–500, 500–600, 600–700, and >700 mm/y. …”
Get full text

A nomogram for predicting 3-year total weight loss percentage following LSG: insights from visceral adipose tissue inflammatory methylation sites by Zhehong Li, Liang Wang, Zheng Wang, Qiqige Wuyun, Buhe Amin, Dongbo Lian, Guangzhong Xu, Nengwei Zhang, Dezhong Wang

“…Comparative analyses of 850K methylation microarrays from VAT samples were performed to identify methylation sites associated with INF-related genes. …”
Get full text

Virtual simulator in oncology for teaching catheter care fully implemented for nursing students: experimental study by Maria das Graças Silva Matsubara Matsubara, Eliza Costa Cijevschi, Leticia Faria Serpa, Antônio Valerio Netto, Daiane Arruda Saraiva, Rita Tarcia

“…Methodology: an experimental, controlled, and randomized study conducted with 55 nursing students. …”
Get full text

Advancing the Use of Longitudinal Electronic Health Records: Tutorial for Uncovering Real-World Evidence in Chronic Disease Outcomes by Feiqing Huang, Jue Hou, Ningxuan Zhou, Kimberly Greco, Chenyu Lin, Sara Morini Sweet, Jun Wen, Lechen Shen, Nicolas Gonzalez, Sinian Zhang, Katherine P Liao, Tianrun Cai, Zongqi Xia, Florence T Bourgeois, Tianxi Cai

“…The pipeline first generates scalable disease outcomes by linking electronic health record data with registry data containing a small sample of labeled outcomes. It then applies causal analysis using these scalable outcomes to evaluate therapies for chronic diseases. …”
Get full text

A genome-wide pleiotropy study between atopic dermatitis and neuropsychiatric disorders by Charalabos Antonatos, Alexandros Pontikas, Adam Akritidis, Dimitra Mitsoudi, Sophia Georgiou, Alexander J. Stratigos, Aikaterini Zacharopoulou, Stamatis Gregoriou, Katerina Grafanaki, Yiannis Vasilopoulos

“…Pleiotropy-informed target prioritization facilitated the identification of novel pathophysiological mechanisms for AD and putative drug targets, such as members of TNF and JAK-STAT3 signaling. Mendelian randomization provided evidence of a causal relationship between genetic liability to MDD and BP in increased AD risk, independent of sample overlap. …”
Get full text

Promoting children's social reasoning about immigration-based exclusion and bystander behavior through literary discussions by Sara Egger, Luciano Gasser, Anna Frei, David Preisig, Hanna Beißert, Hanna Beißert, Hanna Beißert, Yvonne Dammert

“…IntroductionThe current study is the first to investigate the effect of an argument-based intervention about children's literature on social reasoning about immigrant-based exclusion.MethodsWith a one-year intervention study, we examined social reasoning regarding inclusion decisions, moral judgments, and various bystander behaviors. A sample of 758 children (M = 10.33 years, SD = 0.68, 48.5% female) from 41 fourth and fifth grade classes participated in the study. …”
Get full text

Hyperspectral Inversion of Soil Cu Content in Agricultural Land Based on Continuous Wavelet Transform and Stacking Ensemble Learning by Kai Yang, Fan Wu, Hongxu Guo, Dongbin Chen, Yirong Deng, Zaoquan Huang, Cunliang Han, Zhiliang Chen, Rongbo Xiao, Pengcheng Chen

“…In this study, we selected a typical copper (Cu) polluted area in the Pearl River Delta of Guangdong Province as the research site and collected Cu content data and indoor soil reflectance spectral data from 269 surface soil samples. First, the soil spectral data were preprocessed using Savitzky–Golay (SG) smoothing, multiplicative scattering correction (MSC), and continuous wavelet transform (CWT) to reduce noise interference. …”
Get full text

Zonal Estimation of the Earliest Winter Wheat Identification Time in Shandong Province Considering Phenological and Environmental Factors by Jiaqi Chen, Xin Du, Chen Wang, Cheng Cai, Guanru Fang, Ziming Wang, Mengyu Liu, Huanxue Zhang

“…On this basis, early-season winter wheat identification was conducted for each zone individually. Training samples were generated using the Time-Weighted Dynamic Time Warping (TWDTW) method. …”
Get full text

Violence Against Pre-hospital Emergency Medical Service Personnel in Guilan Province, Iran: A Cross-Sectional Study by Payman Asadi, Mohsen Esmaeili, Nazanin Noori Roodsari, Elham Gheysvandi, Enayatollah Homaie Rad

“…The mean age of the participants was 34.89±3.65 years and all of them were male. About 61.8% of the samples experienced some kind of physical or verbal violence in the past 3 months. …”
Get full text

Interpretable Multi-Sensor Fusion of Optical and SAR Data for GEDI-Based Canopy Height Mapping in Southeastern North Carolina by Chao Wang, Conghe Song, Todd A. Schroeder, Curtis E. Woodcock, Tamlin M. Pavelsky, Qianqian Han, Fangfang Yao

“…This study presents an explainable machine learning framework that integrates sparse GEDI LiDAR samples with multi-sensor remote sensing data to improve both the accuracy and interpretability of forest canopy height estimation. …”
Get full text

Effectiveness of eHealth interventions for reducing mental health conditions in employees: A systematic review and meta-analysis. by Elizabeth Stratton, Amit Lampit, Isabella Choi, Rafael A Calvo, Samuel B Harvey, Nicholas Glozier

“…However, there are good reasons why the efficacy identified in clinical or other samples may not generalize to employees, and many Apps are being developed specifically for this group. …”
Get full text

Examination of non-conventional dysplasias adjacent to colorectal adenocarcinoma in patients with IBD by Szintia Almási, Zsófia Balajthy, Bence Baráth, Zsófia Krisztina Török, Panna Szaszák, Tamás Lantos, Bence Kővári, Anita Sejben

“…As multiple recent publications reported evidence of a worse prognosis and more common flat morphology compared to conventional dysplasias, their recognition is of great importance, and stricter follow-up with random biopsy samples may be considered.…”
Get full text

Distribution and phylogenetic analysis of porcine parvoviruses in the wild boar population of Russia by Alina Komina, Nikita Krasnikov, Maria Simakova, Valentina Rykova, Elena Zhukova, Alexander Bulgakov, Anton Yuzhakov

“…Since wild boars are a reservoir for PPVs, the aim of this study was to investigate their prevalence and genetic diversity in the wild boar population. Tissue samples (spleen, lungs, and lymph nodes) collected from 108 wild boars from three regions of Russia during 2021–2024 were analyzed. …”
Get full text

Role of Aging in Ulcerative Colitis Pathogenesis: A Focus on ETS1 as a Promising Biomarker by Ni M, Peng W, Wang X, Li J

“…Finally, the expression levels of key genes were determined in a dextran sulfate sodium (DSS)-induced UC mouse model by qRT-PCR.Results: UC samples were classified into two subtypes (1 and 2), which displayed significant differences in the immune landscape and JAK/STAT signaling pathways. …”
Get full text

Three-dimensional linkage analysis with digital PCR for genome integrity and identity of recombinant adeno-associated virus by Tam Duong, Michele Firmo, Chien-Ting Li, Bingnan Gu, Peng Wang

“…In this study, we focus on evaluating our 3D linkage mathematical model by performing DNA mixing experiments and a case study using multiple rAAV samples. Particularly, we rigorously tested our algorithms by conducting experiments involving the mixing of seven DNA fragments to represent various AAV viral genome populations, including 3 single partials, 3 double partials, and 1 full-length genomes. …”
Get full text

Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: an observational study of 17,345 persons. by Krista Fischer, Johannes Kettunen, Peter Würtz, Toomas Haller, Aki S Havulinna, Antti J Kangas, Pasi Soininen, Tõnu Esko, Mari-Liis Tammesoo, Reedik Mägi, Steven Smit, Aarno Palotie, Samuli Ripatti, Veikko Salomaa, Mika Ala-Korpela, Markus Perola, Andres Metspalu

“…<h4>Methods and findings</h4>106 candidate biomarkers were quantified by nuclear magnetic resonance spectroscopy of non-fasting plasma samples from a random subset of the Estonian Biobank (n = 9,842; age range 18-103 y; 508 deaths during a median of 5.4 y of follow-up). …”
Get full text

Predictive performance and uncertainty analysis of ensemble models in gully erosion susceptibility assessment by Congtan Liu, Haoming Fan, Yixuan Wang

“…A total of 25 Geo-Environmental Factors (GEFs) were selected to build datasets, supplemented by a gully inventory map comprising 823 gullies, resulting in 12,946 samples of both gully and non-gully occurrences. 3 ensemble methods including probability mean (PM), Probability Weighted Mean (PWM), and Probability Empirical Weighted Mean (PEWM) were used. …”
Get full text