Synthetic Dataset Generation Method for Object Detection by Ningning Zhou, Tong Li

“…Abstract To address the high construction cost of datasets for object detection, particularly in industrial application scenarios where sufficient sample images cannot be obtained from the Internet due to the specialized nature and diversity of objects and their working environments, this paper proposes a method to automatically generate synthetic datasets and train object detection models on them. …”
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The effectiveness of online Eye Movement Desensitization and Reprocessing 2.0 Group Protocol on post-traumatic stress disorders symptoms, depression, anxiety, and stress in individ... by Alişan Burak Yasar, İbrahim Gundogmus, Derin Kubilay, Görkem Alban Tunca, Ersin Uygun, Zeynep Zat Çiftçi, Önder Kavakcı, Önder Kavakcı

“…This study aims to investigate the efficacy of the online EMDR 2.0 Group Protocol(EMDR 2.0 GP) versus Improving Mental Health Training for Primary Care Residents(mhGAP) on individuals with a history of traffic accidents in a controlled way.MethodsIn this randomized-controlled study sample includes volunteers who were involved in traffic accidents and were given the randomized online EMDR 2.0 GP and mhGAP Stress management module. …”
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Causal relationship analysis of MRI measurements of major human internal organs and liver disease by Huanyu Wu, Danjing Zhou, Jinggang Zhu, Jianchun Tu

“…Abstract Background This study aimed to explore the causal association between imaging measurement indicators of major internal organs and liver lesions using a two-sample Mendelian randomization (MR) method. Methods Data from the UK Biobank and GWAS Catalog platform were used to select single nucleotide polymorphisms (SNPs) associated with MRI or derived measurement results of various organ indicators as genetic instrumental variables. …”
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Identification of 7-HOCA as a Potential Biomarker in Glioblastoma: Evidence from Genome-Wide Association Study and Clinical Validation by Zhao Z, Xing N, Sun G

“…Concurrently, GBM was designated as the outcome. A two-sample bidirectional MR study was conducted to investigate the potential association. …”
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Genetically predicted immune cells mediate the association between gut microbiota and autoimmune liver diseases by Jikang Zhang, Yiqi Hu, Jin Xu, Hua Shao, Qingping Zhu, Hao Si

“…This study utilizes the Mendelian Randomization (MR) method to investigate the causal relationships among gut microbiota, immune cells, and AILDs.MethodsInitially, we conducted a two-sample MR analysis to predict the causal relationships among 412 gut microbiota, 731 immune phenotypes, and AILDs. …”
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The effect of isoflurane versus propofol-based total intravenous anesthesia on hemodynamic stability, intraoperative blood loss, surgical field quality, recovery characteristics, a... by Alireza Abdi, Behzad Imani, Mohsen Zarei, Sajjad Abdolmaleki, Shirdel Zandi, Roya Najafi Vosough

“…A total of sixty-six patients were randomly assigned to two groups—Isoflurane and TIVA—using a convenience sampling method. …”
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Integrating plasma circulating protein-centered multi-omics to identify potential therapeutic targets for Parkinsonian cognitive disorders by Tayier Tuersong, Yu Xuan Yong, Yan Chen, Pei Shan Li, Samire Shataer, Munire Shataer, Liang Ying Ma, Xin Ling Yang

“…As no effective treatment exists, this study aimed to find potential drug targets for PD cognitive disorders. Methods Two-sample Mendelian randomization (MR) and transcriptome analysis were used to identify PD biomarkers. …”
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Dissecting immune-mediated pathways in rheumatoid arthritis: A multivariate mediation analysis of antibodies and circulating proteins by Jingmin Niu, Pingxin Zhang, Wei Liu, Song Sun, Yingkai Zhang, Jinghao Sang, Jialin Yang, Qin Zhang, Limin Chai

“…This study investigates the causal relationships between antibody immune responses, plasma circulating proteins, and the development of RA using Mendelian Randomization (MR) analysis; A two-sample and multivariate MR analysis was conducted to explore the mediating causal relationship between 46 antibody immune responses and RA through 4,907 plasma circulating proteins. …”
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Causal relationships between alterations in shear stress-related genes and aneurysmal subarachnoid hemorrhage by Xiaoxin Wu, Yuanyuan Dai, Xingyang Niu, Minghao Zhang, Jiaoxing Li, Yi Xie, Wenli Sheng, Fei Ye

“…An integrative analysis of genome-wide association study data for aSAH with eQTLs was conducted using bidirectional two-sample Mendelian randomization (MR) to identify SS-related genes causally linked to aSAH. …”
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Novel insights into the association between genetically proxied inhibition of proprotein convertase subtilisin/kexin type 9 and risk of sarcopenia by Hongyan Jiang, Lulu Li, Xue Zhang, Jia He, Chuanhuai Chen, Ruimin Sun, Ying Chen, Lijuan Xia, Lei Wen, Yunxiang Chen, Junxiu Liu, Lijiang Zhang, Wanqiang Lv

“…Methods We performed a two‐sample Mendelian randomization (MR) study to investigate the causal association between the use of genetically proxied lipid‐lowering drugs (including statins, ezetimibe, and PCSK9 inhibitors, which use low‐density lipoprotein as a biomarker), and sarcopenia risk. …”
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Bioinformatics‑Based Analysis Reveals Diagnostic Biomarkers and Immune Landscape in Atopic Dermatitis by Yang M, Zhang X, Zhou C, Du Y, Zhou M, Zhang W

“…This study aimed to investigate key differentially expressed genes (DEGs) in AD and their association with immune cell infiltration patterns.Methods: The GSE32924 dataset comprises gene expression data from 25 AD samples and 8 control samples. Differential expression analysis was performed using the R package limma. …”
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Clinical effects of Bifidobacterium Longum Subsp. Infantis YLGB-1496 on children with respiratory symptoms by Pin Li, Uma Mageswary, Adli Ali, Fahisham Taib, Thai Hau Koo, Azianey Yusof, Hua Jiang, Hanglian Lan, Weilian Hung, Min-Tze Liong, Yumei Zhang

“…ObjectivesThis study aimed to examine the effects of Bifidobacterium longum subsp. infantis YLGB-1496 (B. infantis YLGB-1496) on the frequency of respiratory illness symptoms and immunity profiles among toddlers.MethodsIn this double-blind, randomized, placebo-controlled, 12-week intervention study, toddlers with at least 2 respiratory illness symptoms were randomly assigned into the probiotic (YLGB-1496) or placebo group at a 1:1 ratio. …”
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The Ancova model for comparing two groups: a tutorial emphasizing statistical distribution theory by Wolf Schwarz

“…I suggest that these issues are best addressed and settled in the context of the underlying exact sampling distribution theory since significance statements, effect size estimates, and statistical power all derive directly from the statistical sampling distribution theory implied by the Ancova model. …”
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Does Multiple Intravenous Tranexamic Acid Doses in Patients Undergoing Total Knee Arthroplasty using Kinematic Alignment without Tourniquet Application show any Difference in Blood... by Farhan Ahmed, Gautam Chatterji, Udit Agrawal, K S Ankitha, Sourav Shukla

“…Further research with larger sample sizes is needed to confirm these findings and explore optimal strategies for blood management in TKA.…”
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Combined posterior superior alveolar and anterior middle superior alveolar nerve blocks with labial infiltration versus nerve blocks alone for pain management in minimally invasive... by Ting-Ting Cai, Jia-Qi Zhang, Meng-Ran Han, Yong-Wei Fu

“…Despite clinical promise, the small sample size limits generalizability, necessitating multicenter trials to validate efficacy and broader applicability. …”
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Exploring potential drug−drug interactions between masculinizing hormone therapy and oral pre‐exposure prophylaxis (F/TDF and F/TAF) among transgender men (iMACT study): a randomiz... by Akarin Hiransuthikul, Narukjaporn Thammajaruk, Stephen Kerr, Rena Janamnuaysook, Siriporn Nonenoy, Piranun Hongchookiat, Rapee Trichavaroj, Yardpiroon Tawon, Jakkrapatara Boonruang, Nipat Teeratakulpisarn, Tim R. Cressey, Peter L. Anderson, Nittaya Phanuphak, the iMACT study team

“…Pharmacokinetic (PK) sampling was conducted at weeks 4 and 12 to assess the impact of PrEP on MHT and at weeks 12 and 16 to evaluate the impact of MHT on PrEP. …”
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Shared Genetic Links Between Nonalcoholic Fatty Liver Disease and Coronary Artery Disease by Hua Di, Shouhao Wang, Chengan Xu, Qiaoqiao Yin, Keyang Xu, Wei Zheng

“…Following this, MAGMA gene set enrichment analysis was conducted to assess the biological significance of these pleiotropic genes. Finally, a two-sample two-way Mendelian randomization (MR) analysis was performed to evaluate causal relationships between NAFLD and CAD. …”
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Exploring the Causal Effect of Mitochondrial DNA Copy Number on Obstructive Sleep Apnea by Ping Ji, Yujiang Fan, Junling Li, Zhaoan Deng, Guofu Zhang, Jianbin Du

“…Method We investigated the causal relationship between mtDNA copy number and OSA based on public genome‐wide association study data utilizing a two‐sample Mendelian randomization (MR) analysis and also explored the mediating role of immune cells between the two using a mediator MR analysis. …”
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Causal Associations Between Chronic Obstructive Pulmonary Disease and Common Comorbidities: Evidence from Comprehensive Genetic Methods by Ji J, Zhao Q, Yuan J, Yuan Z, Gao N

“…Therefore, causal relationships between diseases need to be explored by means of causal inference methods.Materials and Methods: Genetic correlation and two-sample Mendelian randomization (MR) analysis were explored to assess the causal relationship between exposures and outcomes with the genome-wide association studies (GWAS) dataset. …”
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Efficacy and safety of danshen class injections in the treatment of coronary heart disease: a network meta-analysis by Shuang Dai, Yukun Ding, Jianbo Guo, Xian Wang

“…Overall, DSDFSY and DSCXQ show better performance in clinical efficacy evaluation and regulation of inflammatory markers, while DH exhibits a more stable effect in regulating oxidative stress. However, larger sample sizes and high-quality RCTs are still necessary to further compare the various DSCIs.Systematic Review Registration[PROSPERO], identifier [CRD42024548928].…”
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