Disability-inclusive graduation programme intervention on social participation among ultra-poor people with disability in North Uganda: a cluster randomized trial by Shanquan Chen, Lena Morgon Banks, Mark T. Carew, Elijah Kipchumba, Calum Davey, Munshi Sulaiman, Hannah Kuper

“…Methods A two-arm, cluster-randomized controlled trial was conducted in four Northern Ugandan districts, involving 96 intervention and 89 control clusters. …”
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The effect of an educational intervention based on a mobile application on women’s knowledge, attitudes, and practices with respect to microplastics and health: a randomized contro... by Zahra Seifi, Fatemeh Zarei, Fazlollah Ahmadi

“…The sample size was calculated via G*Power software to ensure sufficient power (80%), with an alpha level of 0.05, resulting in a 15% dropout rate. …”
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Effects of celery (Apium graveolens) on blood pressure, glycemic and lipid profile in adults: a systematic review and meta-analysis of randomized controlled trials by Dangzhen Liu, Haiyan Zhao, Hong Xu, Jingqing Hu, Jingqing Hu, Jingqing Hu, Jingqing Hu

“…Data were analyzed using either a random-effects model or a fixed-effects model, depending on heterogeneity, and were presented as standardized mean differences (SMDs) with corresponding 95% confidence intervals (CIs). …”
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Cognitive-motor dual-task training on gait and balance in stroke patients: meta-analytic report and trial sequential analysis of randomized clinical trials by Lu Zhang, Jiangping Ma, Xiaoqing Liu, Aiping Jin, Kai Wang, Xiaobing Yin

“…Trial Sequential Analyses demonstrated larger sample sizes are required for confirming our findings. …”
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Glucosafe 2-A new tool for nutritional management and insulin-therapy in the intensive care unit: Randomized controlled study (the Glucosafe 2 protocol). by Aude de Watteville, Ulrike Pielmeier, Mariagrazia Di Marco, Angèle Gayet-Ageron, Nils Siegenthaler, Nicolas Parel, Hannah Wozniak, Steve Primmaz, Jérôme Pugin, Steen Andreassen, Claudia Paula Heidegger

“…<h4>Method and design</h4>This study is an unblinded randomized controlled study with: (1) the intervention group, which uses the GS2 device for nutritional therapy and blood glucose advice until discharge from the ICU or up until 15 days after study enrolment; (2) the control group, which uses standard care according to local ICU protocols. …”
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Phage therapy with nebulized cocktail BX004-A for chronic Pseudomonas aeruginosa infections in cystic fibrosis: a randomized first-in-human trial by Iddo Weiner, Maya Kahan-Hanum, Nufar Buchstab, Lior Zelcbuch, Sharon Navok, Irit Sherman, Julian Nicenboim, Tim Axelrod, Dikla Berko-Ashur, Maya Olshina, Ron Mordoch, Jagoda Jablonska, Tamar Gera-Inbar, Ilya Vainberg-Slutskin, Britny Blumenfeld, Hila Sberro-Livnat, Ayelet Moses, Hadas Nevenzel, Inbal Levy-Saar, Jenia Gold, Meital Goldberg, Nina Tchernorudsky, Noa Ben-Yishay, Tal Cohen, Edith Kario, Inesa Levovich, Roman Safonov, Yaron Tzur, Yulia Zarchin, Vered Lev, Yifat Elharar, Einav Safyon-Gartman, Inbar Gahali-Sass, Sailaja Puttagunta, Xilla Ussery, Regis Vilchez, Urania Rappo, Naomi Zak, Myriam Golembo, Ariel Cohen, Jon Koff, Eitan Kerem, Rotem Sorek, Merav Bassan

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The effect of pomegranate products on glycemic profile in adults: a GRADE- assessed systematic review and dose-response meta-analysis of randomized controlled trials by Fatemeh Mohammadzaheri, Fatemeh Sheikhhossein, Amirhossein Hemmati, Seyed Mojtaba Ghoreishy, Mohsen Mohammadi-Sartang, Farideh Shiraseb, Seyed Ali Keshavarz

“…More RCTs with longer duration and larger sample sizes are needed to confirm these findings.…”
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A Remote Intervention Based on mHealth and Community Health Workers for Antiretroviral Therapy Adherence in People With HIV: Pilot Randomized Controlled Trial by Shivesh Shourya, Jianfang Liu, Sophia McInerney, Trinity Casimir, James Kenniff, Trace Kershaw, David Batey, Rebecca Schnall

“…MethodsThis mixed methods pilot study involved 40 participants with HIV, who were randomly assigned to a control group (n=20, 50%) or the CHAMPS intervention (n=20, 50%) over 3 months. …”
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Physical education exercise improves physical fitness and working memory function: a randomized controlled trial study of Uyghur adolescents in Xinjiang, China by Xiaodi Cai, Yuefeng Liu, Yanhong Li, Zhiqiang Chen

“…The effects of physical education exercise on physical fitness and working memory function of Uyghur adolescents were analyzed. Methods Randomly selected 222 Chinese Xinjiang Uyghur secondary school students were randomly divided into a control group and an exercise intervention group. …”
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Dry needling as an adjunct treatment to multimodal rehabilitation protocol following rotator cuff repair surgery: a preliminary, randomized sham-controlled trial by Faeze Naseri, Mehdi Dadgoo, Mohammadreza Pourahmadi, Morteza Nakhaei Amroodi, Shirin Azizi, Amirhossein Shamsi

“…Future studies should consider different control groups, long-term follow ups, larger sample sizes, and more MTrP-DN sessions to better understand their potential impact. …”
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Antenatal group-based psychoeducation to improve postpartum depression literacy in primary health care institutions in Ethiopia: a cluster randomized controlled trial by Marta Tessema, Muluemebet Abera, Zewdie Birhanu

“…So, this study assessed the effectiveness of antenatal group psychoeducation in improving PPD literacy among pregnant women in Jimma, Ethiopia.MethodsA cluster randomized controlled trial was conducted from 28 March to 1 December 2022 involving 32 non-adjusted health centers that were randomized into two groups (16 health centers for each arm). …”
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Validating the pathogenic mechanism of chronic obstructive pulmonary disease induced by negative emotions via Mendelian randomization and traditional Chinese medicine theory of emo... by Zhiying Wang, Yun Li, Zhixian Zhong, Ling Xu, Yi Zhong, Jian Chen

“…Objective: We employed Mendelian randomization (MR) to test the traditional Chinese medicine (TCM) theory of emotional pathogenesis concept and explore the causal relationship between negative emotions and chronic obstructive pulmonary disease (COPD). …”
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Development and implementation of an “Internet ” integrated service model for antepartum, intrapartum, and postpartum care in maternal and child specialty hospitals: A randomized c... by Chen Shaochuan, He Lianci, Zhang Qiongyue, Wang Xin, Xie Huiqiong, Tan Ying, Feng Xiaohui, Li Huimin

“…Methods Using a convenience sampling method, 100 pregnant and postpartum women from a tertiary maternal and child health hospital in Chengdu, China, were selected as the participants for this study. …”
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Erector spinae plane block versus caudal epidural block in pediatric surgery: a systematic review and meta-analysis of randomized clinical trials by Barbara Bombassaro Masiero, Deivyd Cavalcante, Fatemeh Akbarpoor, Capela António Dicazeco Pascoal, Lubna Al-Sharif, Fellipe Feijó Halfeld, Lucas Cael Azevedo Ramos Bendaham, Patricia Viana, Jesslyn N. Haryianto, Maria Luiza de Souza Rasia, Mariana Copetti de Almeida Cunha, Ana Djulia Tesche, Júlia Caletti Roth de Oliveira, Rafael Arsky Lombardi

“…Methods: We searched PubMed, Embase and Cochrane Central for Randomized Controlled Trials (RCTs) comparing ESPB versus CEB in pediatric patients undergoing abdominal and sub-abdominal surgeries. …”
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Effects of Xiangshao granules on clinical symptoms and serum hormone levels of menopausal syndrome: a systematic review and meta-analysis of randomized controlled trials by Xing Tang, Chengcheng Wang, Yang Liu, Yisha Xu, Shoujin Dong, Min Dai, Chunmei Li, Yan Zhai, Shoujen Lan, Yeayin Yen, Chao Wang, Congcong Yu

“…In the future, multi-center and large sample randomized controlled trials can be conducted for more key clinical indicators to comprehensively analyze the clinical efficacy and applicability of Xiangshao granules in the treatment of MPS.Systematic review registrationhttps://www.crd.york.ac.uk/, identifier CRD42023405228.…”
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Exploring potential causal effects of circulating inflammatory proteins on hematologic malignancies and identifying cross-cancer drug targets: a Mendelian randomization study by Chaoqun Lu, Minghui Wang, Jiang Li, Huajian Xian, Zixuan Huang, Yixin Wang, Shufeng Xie, Wenjie Zhang, YaoYifu Yu, Huijian Zheng, Dan Li, Yuling Zheng, Han Liu, Chunjun Zhao

“…Therefore, it’s necessary to explore the possible causal relationships between specific circulating inflammatory proteins and these malignancies by using a genome-wide association approach.Methods: To evaluate the possible causal effects, we performed a two-sample Mendelian randomization (MR) study. Summary statistics for 91 proteins, sourced from large-scale genome-wide association studies, were integrated with data on 11 hematologic malignancies from the FinnGen consortium. …”
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Disentangling the divergent causal pathways underlying the association between body mass index and bone mineral density: a comprehensive Mendelian randomization study by Xunying Zhao, Lin He, Xueyao Wu, Li Zhang, Jinyu Xiao, Changfeng Xiao, Yang Qu, Jingwei Zhu, Chenjiarui Qin, Deqin Huang, Pengyue Shen, Tao Han, Mengyu Fan, Jiayuan Li, Stephen Burgess, Xia Jiang

“…Methods Leveraging the hitherto largest genome-wide summary statistics, we conducted a two-sample Mendelian randomization (MR) to re-evaluate the effect of genetically predicted BMI on eBMD. …”
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Therapeutic-dose heparin combined with antiplatelets in noncritically ill patients with COVID-19: a secondary analysis of a multiplatform randomized controlled trial by Sylvain A. Lother, Wen Teng, Olawale Ayilara, Brett L. Houston, Barret Rush, Srinivas Murthy, Jose C. Nicolau, Lindsay Bond, Alexis F. Turgeon, John C. Marshall, Jonathan Paul, Judith S. Hochman, Matthew D. Neal, Michael E. Farkouh, Joel Nkosi, Donald S. Houston, Charlotte A. Bradbury, Asher A. Mendelson, Ewan C. Goligher, Allan Garland, Robert Balshaw, Souradet Y. Shaw, Patrick R. Lawler, Yoav Keynan, Ryan Zarychanski

“…After applying inverse probability of treatment weighting, the effective sample size was 60 in the combination group and 652 in the control group. …”
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Safety and efficacy of rotigotine in patients with frontotemporal dementia: a phase 2, double-blind, randomized, placebo-controlled, multicenter trialResearch in context by Giacomo Koch, Martina Assogna, Yasmine Gadola, Antonella Alberici, Francesco Di Lorenzo, Sonia Bonnì, Ilaria Borghi, Emanuele Cerulli Irelli, Lucia Mencarelli, Michele Maiella, Romina Esposito, Elias Paolo Casula, Valentina Pezzopane, Alessia D'Acunto, Francesca Candeo, Matteo Ferraresi, Gisella Guerrera, Luca Battistini, Enrico Premi, Valeria Bracca, Silvia Lucchini, Francesco Bertagna, Pasquale Romano, Andrea Ludovici, Antonio Daniele, Caterina Motta, Clarissa Ferrari, Alessandro Martorana, Barbara Borroni

“…Randomization was centralized and performed using a double-blind covariate-adaptive scheme. …”
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The Effect of compound exercises using the (RANDOM SHOT) device and the electronc goal ln developing the speed of the motor response and the rapid ability of the two goal keepers y... by Diana Haider, Dr. Widad Kadhum

“… The research problem shaped through the entry of complex exercises with the introduction of scientific devices as a Random Shot, and the electronic goal when applying goalkeepers exercises for the national football team for halls. …”
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