Immune Microenvironment Characterization and Machine Learning-Guided Identification of Diagnostic Biomarkers for Ulcerative Colitis by Zheng Q, Wang L, Zhang Y, Peng J, Hou J, Wang H, Ma Y, Tang P, Li Y, Li H, Chen Y, Li J, Chen Y

“…Moreover, machine learning models, including Random Forest and Best Subset Selection, were used to construct and validate an optimal diagnostic framework. …”
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Mortality impact, risks, and benefits of general population screening for ovarian cancer: the UKCTOCS randomised controlled trial by Usha Menon, Aleksandra Gentry-Maharaj, Matthew Burnell, Andy Ryan, Jatinderpal K Kalsi, Naveena Singh, Anne Dawnay, Lesley Fallowfield, Alistair J McGuire, Stuart Campbell, Steven J Skates, Mahesh Parmar, Ian J Jacobs

“…Randomisation The trial management system confirmed eligibility and randomly allocated participants using computer-generated random numbers to MMS, USS and C groups in a 1:1:2 ratio. …”
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Effects of Video-Guided Active Breaks on Motor Competence of Schoolchildren with Special Education Needs by Alejandra Robles-Campos, Daniel Reyes-Molina, Karen Kracht-Suazo, Igor Cigarroa, Jaime Cárcamo-Oyarzun, Nicolas Martinez-Lopez, Margarita Perez-Ruiz, Alberto Grao-Cruces, Jorge Mota, Alberto Ruiz-Ariza, Fernando Muñoz Hinrichsen, Guillermo García-Pérez-de-Sevilla, Carlos Celis-Morales, Rafael Zapata-Lamana

“…Methods: A prespecified subanalysis of a multicenter randomized controlled trial was conducted with a sample of 161 schoolchildren (7.8 ± 1.1 years, 32% girls) with special educational needs from five public schools in Chile. …”
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A pilot study of disulfiram for individuals with persistent symptoms despite prior antibiotic treatment for Lyme disease by Mara Kuvaldina, Mara Kuvaldina, Jessica Preston, Jessica Preston, Denise McClellan, Denise McClellan, Martina Pavlicova, Thomas H. Brannagan, Brian A. Fallon, Brian A. Fallon, Brian A. Fallon

“…Efficacy could not be assessed given the small sample size and the lack of a placebo-control group.Clinical trial registrationhttps://clinicaltrials.gov/study/NCT03891667?…”
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Efficacy and safety of telitacicept in systemic lupus erythematosus with lupus nephritis and nephrotic syndrome: a 12-month retrospective cohort study by Min-Ying Liu, Min-Ying Liu, Min-Ying Liu, Liu-Jun Li, Ting Li, Hao-Sen Zhu, Hao-Sen Zhu, Chang-Song Lin, Chang-Song Lin, Chang-Song Lin, Qiang Xu, Qiang Xu, Qiang Xu, Qing-Ping Liu, Qing-Ping Liu, Qing-Ping Liu

“…These practical findings support its potential as a targeted therapy for renal and hematological manifestations of SLE, requiring further validation through randomized controlled trials.…”
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Comparative Analysis of Single-row and Double-row Arthroscopic Shoulder Rotator Cuff Repair: Impacts on Patient-reported Outcomes, Strength, and Range of Motion by Abrar H Mekkamannil, Jeganathan Parthiban, Suresh Perumal, Sanjay A K, Rohit KR

“…The study’s limitations include a small sample size, lack of randomization, and potential confounding factors that may have influenced the outcomes. …”
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Evaluation of Morphological Traits, Yield and Yield Components of Faba Bean (Vicia faba L.) under Different Levels of Chemical Fertilizers in Paddy Fields by Mohammad Rabiee, Sajjad Shaker Kouhi

“…The protein content of samples was determined by the Kejeldahl method. After measurement of the sample total nitrogen by applying factor 6.25, the seed protein content was measured. …”
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Development and evaluation of predictive models for pregnancy risk in UK dairy cows by Matthew Barden, Robert Hyde, Martin Green, Andrew Bradley, Edna Can, Rachel Clifton, Katharine Lewis, Al Manning, Luke O'Grady

“…Data from a convenience sample of 108 dairy herds in the UK were collated, and each herd was randomly allocated, at a ratio of 80:20, to either training or testing datasets. …”
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Potential therapeutic benefits of curcumin in depression or anxiety induced by chronic diseases: a systematic review of mechanistic and clinical evidence by Jiyuan Yuan, Jiyuan Yuan, Jiyuan Yuan, Chao Pi, Hongping Shen, Bi Zhou, Yumeng Wei, Nathupakorn Dechsupa, Ling Zhao, Ling Zhao

“…However, the conclusions should be interpreted with caution due to considerable heterogeneity across studies, limited sample size, variations in curcumin formulations and dosages, and potential publication bias. …”
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Healing through faith: Meeting a chaplain coupled with biblical readings could produce lymphocyte changes that correlate with brain activity (HEALING study) [version 5; peer review... by András Béres, Csaba Aranyi, Miklós Emri, Éva Perpékné Papp, Edit Hörcsik, Márta Kuti, Ferenc Tomanek, Ferenc Nagy, Dániel Fajtai, Pál Bödecs, Péter Szabó, Eszter Vinczen, Bettina Bakos, Renáta Sillinger, Eszter Gál, Hajnalka Kisdeákné, Ágnes Petőfalviné, Dániel Kovács, Gergely Bíró, Tamás Németh, Judit Fodor, Imre Repa, Erzsébet Papp, Antal Szilágyi, Zoltán Szalai, György Nagyéri, Marianna Kiss-Merki

“…No meeting occurred in the randomized control group (n = 19). Blood samples were obtained 30 min prior and 60 min after the meeting to measure white blood cell (WBC) count, interferon-gamma (IFN-γ), immunoglobulin M (IgM), IgA, IgG, and complement 3 (C3). …”
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Modeling Factors Influencing Project Financing Risk by Gholamreza Sharafi, Kiamars Fathi Hafashjani, Faegh Ahmadi

“…The study's statistical population comprises a diverse range of professionals, including experts, senior experts, supervisors, and managers from mining companies within the country under study. From this pool, a sample of 220 individuals was randomly selected to ensure robustness and representativeness in the analysis. …”
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Effectiveness of a brief behavioural intervention on psychological distress among women with a history of gender-based violence in urban Kenya: A randomised clinical trial. by Richard A Bryant, Alison Schafer, Katie S Dawson, Dorothy Anjuri, Caroline Mulili, Lincoln Ndogoni, Phiona Koyiet, Marit Sijbrandij, Jeannette Ulate, Melissa Harper Shehadeh, Dusan Hadzi-Pavlovic, Mark van Ommeren

“…<h4>Conclusions</h4>Among a community sample of women in urban Kenya with a history of GBV, a brief, lay-administered behavioural intervention, compared with EUC, resulted in moderate reductions in psychological distress at 3-month follow-up.…”
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Eficacia del entrenamiento interválico de alta intensidad versus entrenamiento continuo moderado en pacientes con insuficiencia cardiaca crónica con fracción de eyección reducida,... by Albert Collados-Gutiérrez, Lourdes Gutiérrez Vilahú

“…Twelve studies with a total sample of 843 patients were included. The articles analyzed showed that, despite the fact that in most of the RCTs there were no significant differences between the application of HIIT or MICT to improve aerobic capacity, LVEF and QoL, there are some in which the data seem to indicate a benefit in aerobic capacity in the use of HITT vs MICT in patients with CHFrEF. …”
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Abstract 040: Hemorrhagic Conversion Patterns After Transition of Stroke Thrombolysis from Alteplase to Tenecteplase; Real‐World Experience by Mohamad Ezzeldin, Courtney Hill, Eryn Percenti, Ali Kerro, Adam Delora, Juan Santos, Hamza Saei, Lisa Greco, Rime Ezzeldin, Mohammad Elghanem, Yazan Alderazi, Yana Kim, Cathleen Poitevint, Osman Mir

“…Introduction Importance:Tenecteplase (TNK) use is more prevalent as the thrombolytic drug of choice for acute ischemic stroke (AIS), given its ease of use with results from randomized trials showing non‐ inferiority and comparable safety to Alteplase (tPA). …”
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Clima motivacional en Educación Física y actividad físico-deportiva en el tiempo libre en alumnado de España, Costa Rica y México (Motivational climate in physical education and sp... by Pilar Vílchez Conesa, Francisco Ruiz-Juan

“…The objective of present study was to determinate relationship between behavior of practice, level of physical activity on leisure and stages of change according to motivational climate of students on Secondary. Sample consisted of 2168 students randomly selected to participate in a longitudinal study of Costa Rica (423), Mexico (408) and Spain (1337), with 1052 boys, 1037 girls and 79 did not reflect sex, aged between 11 and 16 years (M = 12.49, SD = .81). …”
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Prenatal maternal stress: triangulating evidence for intrauterine exposure effects on birth and early childhood outcomes across multiple approaches by Ingunn Olea Lund, Laurie J. Hannigan, Helga Ask, Adrian D. Askelund, Laura Hegemann, Elizabeth C. Corfield, Robyn E. Wootton, Yasmin I. Ahmadzadeh, George Davey Smith, Tom A. McAdams, Eivind Ystrom, Alexandra Havdahl

“…We assessed associations using four approaches: sibling control analyses, gene-environment interaction analyses, intergenerational Mendelian randomization (MR), and negative control (i.e., postnatal stress) analyses. …”
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A valuable predictive model for optimizing the timing of oocyte retrieval: a retrospective analysis of oocyte retrieval time in 49,961 oocyte pickup (OPU) cycles by Yuting Huang, Zhe Kuang, Xi Shen, Yunhan Nie, Yuqi Zeng, Yali Liu, Li Wang

“…The data from Group 1 was randomly divided into training and validation sets using the "sample" function in R software. …”
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Exploring the genetic associations and causal relationships between antibody responses, immune cells, and various types of breast cancer by Yang Yang, Jiayi Chen, Fuhong Gong, Jingge Miao, Mengping Lin, Ruimin Liu, Chenxi Wang, Fei Ge, Wenlin Chen

“…However, limitations such as GWAS sample size constraints and unclear specific pathophysiological mechanisms need further improvement and validation in future studies.…”
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Analysis of clinical features, prognosis and comprehensive therapeutic strategies in 261 patients with limited-stage esophageal small cell carcinoma by LIU Di, NI Jianjiao, ZHAO Kuaile, XIANG Jiaqing, ZHANG Zhen, ZHANG Junhua

“…Conclusion: This large-sample retrospective study with comprehensive datasets and long-term follow-up demonstrated comparable survival outcomes between radical chemoradiotherapy and radical surgery plus adjuvant chemotherapy for LS-SCEC. …”
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ALDH2 mediates the effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on improving cardiac remodeling by Han Liu, Bingchen Jiang, Rui Hua, Xuehao Liu, Bao Qiao, Xiangxin Zhang, Xilong Liu, Wenjun Wang, Qiuhuan Yuan, Bailu Wang, Shujian Wei, Yuguo Chen

“…Methods Analysis of multiple transcriptomic datasets and two-sample Mendelian randomization were performed to find out the differentially expressed genes between pathological cardiac hypertrophy models (patients) and controls. …”
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