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Dissecting the causal effects of interleukin receptor-related factors and the risk of developing endometriosis: a two-sample Mendelian randomization study
Published 2025-12-01“…This study investigates the causal associations between interleukin receptor-related factors and the development of endometriosis, as their etiology and pathophysiology remain largely unknown. A two-sample Mendelian randomization (MR) approach was employed to analyze genetic variants associated with interleukin receptor related factors as instrumental variables (IVs). …”
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The causal association of cheese intake with type 2 diabetes mellitus: results from a two-sample Mendelian randomization study
Published 2024-05-01“…To evaluate this relationship, we performed a two-sample Mendelian randomization (MR) study. Material and methods Summary cheese intake statistics were obtained from UK Biobank and publicly available genome-wide association studies (GWAS) for type 2 diabetes from IEU OpenGWAS, FinnGen Biobank, EBI GWAS, and Biobank Japan. …”
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Causal relationship between 731 immune cells and the risk of diabetic nephropathy: a two‑sample bidirectional Mendelian randomization study
Published 2024-12-01“…We aimed to further evaluate the causal association between immune cells and DN using bidirectional two-sample Mendelian randomization (MR) analysis.Method The DN data were retrieved from the IEU OpenGWAS Project database, while the data for 731 immune cells were sourced from GWAS summary statistics by Orru ̀ et al. …”
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Causal relationship between Helicobacter pylori infection and IgA nephropathy: a bidirectional two-sample mendelian randomization study
Published 2024-12-01“…In this study, we investigated whether there is a causal relationship and reverse causality between IgAN and H. pylori infection by using a bidirectional two-sample Mendelian randomization (MR) analysis. This study was estimated using inverse variance weighted (IVW), MR-Egger and weighted median methods, with the IVW method having the strongest statistical efficacy. …”
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Coffee Intake, Plasma Caffeine Levels, and Kidney Function: Two-Sample Mendelian Randomization Among East Asian and European Ancestries
Published 2024-04-01“…We aimed to evaluate this causal relationship using two-sample MR among both East Asian and European ancestries and to explore underlying mechanisms using plasma caffeine levels. …”
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Genetic Insights Into Lipid Traits and Lipid-Modifying Drug Targets in Pregnancy Complications: A Two-Sample Mendelian Randomization Study
Published 2025-01-01“…Huijing Shao,1,* Chang Xu,2,* Caihong Zhang,2 Lirong Li,3 Pengfei Wu,4 Zixi Chen,5 Rui Guan2 1Department of Obstetrics and Gynecology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of China; 2Department of Obstetrics and Gynecology, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, People’s Republic of China; 3Department of Traditional Chinese Gynecology, China-Japan Friendship Hospital, Beijing, 100029, People’s Republic of China; 4Department of Obstetrics and Gynecology, Hospital of Obstetrics and Gynecology, Shanghai Medical School, Fudan University, Shanghai, 200080, People’s Republic of China; 5Department of Laboratory Medicine, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, People’s Republic of China*These authors contributed equally to this workCorrespondence: Rui Guan, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Naval Medical University, No. 168 Changhai Road, Yangpu District, Shanghai, 200433, People’s Republic of China, Email cngreen785@163.comBackground: Dyslipidemia is linked to pregnancy complications, but its causal role remains uncertain. This two-sample Mendelian Randomization (MR) study investigated the causal relationship between lipid traits and pregnancy complications and evaluated the impact of lipid-modifying drug targets.Methods: Genetic instruments for lipid traits and targets for lipid-modifying drugs were obtained from the Global Lipids Genetics Consortium. …”
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Elliptical Model-Based Robust Pedestrian Pose Tracking by LiDAR via Bi-Level Moving Horizon Random Sample Consensus
Published 2025-01-01Subjects: Get full text
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A simple way of improving the Bar–Lev, Bobovitch and Boukai Randomized response model
Published 2017-11-01Subjects: Get full text
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An Efficient and Stable Registration Framework for Large Point Clouds at Two Different Moments
Published 2024-11-01Subjects: Get full text
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Adaptive Prediction of a Random Process Using a Sequential Regression Algorithm
Published 2020-01-01Subjects: Get full text
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Causal Associations of Epigenetic Age Acceleration With Stroke and Its Functional Outcome: A Two‐Sample, Two‐Step Mendelian Randomization Study
Published 2025-03-01“…Methods We conducted a two‐sample Mendelian randomization (MR) analysis to explore the causal relationships between epigenetic age and stroke and its outcomes. …”
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Association of Sleep Traits, Physical Activity, and Sedentary Leisure Behavior With Female Reproductive Health: A Two-Sample Mendelian Randomization Analysis
Published 2025-02-01“…Because of this, female reproductive health can be promoted through living habit adjustment.Methods: We used two-sample Mendelian randomization analysis with summary datasets from a genome-wide association study to investigate the causal relationships between sleep traits, sedentary leisure behavior, physical activity, and reproductive health traits in women, calculating odds ratios (ORs) and 95% confidence intervals (CIs). …”
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Enhancing image quality in circular-view photoacoustic tomography using randomized detection points
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