Dietary Tribulus Terrestris as a functional food combined with blood flow restriction to enhance the jump performance of basketball athletes: a randomized crossover study by Junhao Kong, Jinda Li, Mingchen Xu, Tao Liu, Zhiyu Xie, Tianhe Li, Yapu Liang

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Effect of Chinese patent medicine Si-Mo-Tang oral liquid for functional dyspepsia: A systematic review and meta-analysis of randomized controlled trials. by Yunxia Hu, Yu Bai, Zhiyun Hua, Jie Yang, Huahui Yang, Wenjun Chen, Junwei Xu, Zhiqiang Zhao

“…A systematic review and meta-analysis of randomized controlled trials (RCTs) were performed to assess the efficacy and adverse effects of SMT for FD.…”
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Effectiveness, Tolerability and Safety of Topical Clobetasol with Oral Hydroxychloroquine versus Topical Clobetasol with NBUVB Phototherapy in Unstable Vitiligo: Investigator Blind... by Dhiman Tarafdar, Indrayudh Sen, Sankha Koley, Biswarup Ray, Pinaki Sarkar, Amrita Sil, Arghyaprasun Ghosh, Nilay K. Das

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Effect of Minimal Individual or Group Enhancement in an eHealth Program on Mental Health, Health Behavior, and Work Ability in Employees With Obesity: Randomized Controlled Trial by Siniriikka A Männistö, Joona Muotka, Laura-Unnukka Suojanen, Raimo Lappalainen, Kirsi H Pietiläinen, Riitta Korpela

“…ObjectiveThis study aimed to explore whether minimal group or individual enhancements could offer additional benefits to an eHealth intervention in relation to mental health, perceived work ability, and health behavior in a sample of occupational health patients with obesity. …”
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The effect of probiotic, prebiotic, and synbiotic supplements on anthropometric measures and respiratory infections in malnourished children: a systematic review and meta-analysis... by Masoumeh Paiandeh, Mahsa Maghalian, Sakineh Mohammad-Alizadeh-Charandabi, Mojgan Mirghafourvand

“…Meta-regression indicated that intervention type, sample size, and follow-up duration were not significant moderators for outcomes related to weight, height, or respiratory infections. …”
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Early formative objective structured clinical examinations for students in the pre-clinical years of medical education: A non-randomized controlled prospective pilot study. by Naïm Ouldali, Enora Le Roux, Albert Faye, Claire Leblanc, François Angoulvant, Diane Korb, Clémence Delcour, Caroline Caula, Delphine Wohrer, Alexis Rybak, Manon Delafoy, Claire Carrié, Marion Strullu, Mehdi Oualha, Romain Levy, Camille Mimoun, Lucie Griffon, Alexandre Nuzzo, Clara Eyraud, Michael Levy, Pierre Ellul

“…A qualitative analysis, using a convenience sample, was conducted by gathering data pertaining to the process through on-site participative observation of the formative OSCE program.…”
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Efficacy of MRI and clinical findings of Lidocaine injection combined with manual therapy in frozen shoulder-A prospective, randomized, single-blinded, sham-controlled trial. by Gopal Nambi, Mshari Alghadier, Elturabi Elsayed Ebrahim, Mudathir Mohamedahmed Eltayeb, Dena Eltabey Sobeh, Osama R Aldhafian, Shahul Hameed Pakkir Mohamed, Naif Nwihadh Alshahrani, Faizan Z Kashoo, Hariraja Muthusamy, Radhakrishnan Unnikrishnan, Alaa Jameel A Albarakati

“…<h4>Study design/ setting</h4>Randomized, single-blinded controlled study conducted at University hospital.…”
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Lifestyle Advice Combined with Personalized Estimates of Genetic or Phenotypic Risk of Type 2 Diabetes, and Objectively Measured Physical Activity: A Randomized Controlled Trial. by Job G Godino, Esther M F van Sluijs, Theresa M Marteau, Stephen Sutton, Stephen J Sharp, Simon J Griffin

“…Key limitations include the recruitment of a sample that may not be representative of the UK population, use of self-reported secondary outcome measures, and a short follow-up period.…”
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Developing a Behavioral Phenotyping Layer for Artificial Intelligence–Driven Predictive Analytics in a Digital Resiliency Course: Protocol for a Randomized Controlled Trial by Trevor van Mierlo, Rachel Fournier, Siu Kit Yeung, Sofiia Lahutina

“…ObjectiveThis 6-arm randomized controlled trial aims to analyze user engagement with randomized tips and to-do lists within a resiliency course tailored for Ukrainian refugees affected by the ongoing humanitarian crisis (Спільна Сила), using the EvolutionHealth.care (V-CC Systems Inc) platform. …”
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A randomized controlled trial for evaluating the effects of an online mindfulness-based intervention for parents of children with attention-deficit/hyperactivity disorder: a study... by Zoe Jiwen Zhang, Herman Hay Ming Lo, Susan M. Bögels, Rebecca Y. M. Cheung, Elsa Ngar-sze Lau, Eric Kam-pui Lee, Siu-Man Ng, Alma Au, Wing Tung Yeung

“…Given the limitations of current online MBI research such as the absence of control groups, small sample sizes, and a low completion rate, this study aims to evaluate the effects of an online family MBI on the outcomes of children with ADHD and their parents. …”
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Adjuvant treatment with Wu-Zi-Yan-Zong formula for abnormal sperm parameters associated with male infertility: a meta-analysis of randomized controlled trials by Feilun Cui, Feilun Cui, Yueshi Zhang, Yu Fan

“…However, further well-designed RCTs with larger sample sizes are necessary to definitively determine the efficacy and safety of the WZYZ formula in treating abnormal sperm parameters associated with male infertility.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/view/CRD42024629510.…”
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The effect of warm saltwater and warm water baths on pain, fatigue, sleep quality, and functional capacity in patients with rheumatoid arthritis: a randomized controlled study✰ by Okşan Aktaş, Ayşe Arikan Dönmez, Sevgisun Kapucu, Muhammet Çinar

“…Methods This three-arm and prospective randomized controlled study fifty-four patients were randomly assigned to three groups (warm salt water: 18; warm water: 18; control: 18). …”
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Comparison of neoadjuvant treatment and surgery first for resectable or borderline resectable pancreatic carcinoma: A systematic review and network meta-analysis of randomized cont... by Lu Huan, Fucai Yu, Ding Cao, Hantao Zhou, Maoling Qin, Yang Cao

“…However, neoadjuvant therapy (NT) seems to increase prognosis of pancreatic carcinoma and come to everyone's attention gradually. Randomized controlled trials offering comparison with the NT are lacking and optimal neoadjuvant treatment regimen still remains uncertain. …”
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Repetitive Transcranial Magnetic Stimulation targeted with MRI based neuro-navigation in major depressive episode: a double-blind, multicenter randomized controlled trial. by Bruno Millet, Ghina Harika-Germaneau, Redwan Maatoug, Florian Naudet, Jean-Michel Reymann, Valérie Turmel, Jean-Marie Batail, Jacques Soulabaille, Nematollah Jaafari, Dominique Drapier

“…Optimization of its efficacy with a neuro-navigation system has been proposed based on a small randomized controlled trial (RCT) supporting a large effect.…”
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The effects of an immersive virtual reality and telemedicine-based multi-component intervention in individuals with subjective cognitive decline: study protocol of a randomized con... by Maria Stefania De Simone, Maria Stefania De Simone, Silvia Zabberoni, Silvia Zabberoni, Alberto Costa, Alberto Costa, Erika Tenaglia, Erika Tenaglia, Gaetano Tieri

“…Our aim is to test the effects of an immersive virtual reality (IVR) and telemedicine-based multi-component intervention, that combines cognitive training and health and lifestyle education program, in individuals with SCD.MethodsTo assess the efficacy of the intervention, a randomized, double-blinded controlled trial will be conducted on a sample of 75 individuals with SCD. …”
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Standard versus double dosing of beta-lactam antibiotics in critically ill patients with sepsis: The BULLSEYE study protocol for a multicenter randomized controlled trial by M. M. B. Horstink, D. R. Geel, C. A. den Uil, P. E. Deetman, H. Endeman, A. Abdulla, T. M. Bosch, W. J. R. Rietdijk, F. W. Thielen, J. J. Haringman, P. van Vliet, T. A. Rijpstra, C. Bethlehem, A. Beishuizen, A. E. Muller, B. C. P. Koch, on behalf of The BULLSEYE investigators

“…Despite anticipated recruitment challenges, its large sample size ensures robust comparability. This pivotal trial could significantly impact sepsis treatment, leading to better clinical outcomes. …”
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Changes in the Brain-Derived Neurotrophic Factor Are Associated with Improvements in Diabetes Risk Factors after Exercise Training in Adolescents with Obesity: The HEARTY Randomize... by Jeremy J. Walsh, Amedeo D’Angiulli, Jameason D. Cameron, Ronald J. Sigal, Glen P. Kenny, Martin Holcik, Steve Doucette, Angela S. Alberga, Denis Prud’homme, Stasia Hadjiyannakis, Katie Gunnell, Gary S. Goldfield

“…This study examined the associations between changes in diabetes risk factors and changes in BDNF levels after 6 months of exercise training in adolescents with obesity. The sample consisted of 202 postpubertal adolescents with obesity (70% females) aged 14–18 years who were randomized to 6 months of aerobic and/or resistance training or nonexercise control. …”
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Association between red blood cell distribution width and genetic risk in patients with rheumatoid arthritis: a prospective cohort study and Mendelian randomization analysis by Mingyang Chen, Jing Lei, Zhenqiu Liu, Renjia Zhao, Yanfeng Jiang, Kelin Xu, Tiejun Zhang, Chen Suo, Xingdong Chen

“…Using previously reported results, we constructed a polygenic risk score for RA to evaluate the joint effects of RDW and RA-related genetic risk. Two-sample mendelian randomization and bayesian colocalization were used to infer the causal relation between them. …”
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Application of Closed Incision Negative Pressure Wound Therapy in Ventral Hernia Repair Surgery Using a Polypropylene Mesh: A Randomized Clinical Trial by Petr Jelinek, Jan Hrubovcak, Radovan Hajovsky, Jan Velicka, Martin Pies

“…<i>Materials and Methods</i>: A randomized study was conducted with 100 patients undergoing ventral hernia repair using a polypropylene mesh. …”
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Tofacitinib Efficacy/Safety in Patients with Ankylosing Spondylitis by Baseline Body Mass Index: A Post Hoc Analysis of Phase 2/3 Trials by Hillary Norton, Paula Sliwinska-Stanczyk, Tomas Hala, Bassel El-Zorkany, Lori Stockert, Rajiv Mundayat, Lisy Wang, Christopher T. Ritchlin

“…This post hoc analysis demonstrates that tofacitinib can be considered as a treatment option for AS, regardless of baseline BMI category; however, interpretation was limited by small sample sizes and differences in sample sizes and baseline characteristics across categories. …”
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