Elucidating genetic variability between randomly bred domestic cats and Persian domestic cats from different geographical locations using microsatellite markers by Shirin Mahmoodi, Ali Hojabr Rajeoni, Mehrshad Zeinolabedini, Arash Javanmard, Mohammad Hossein Banabazi

“…Conclusions On this basis, we conclude that randomly bred domestic cats have a higher level of diversity than Persian domestic cats. …”
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A scalable mental health intervention for depressive symptoms: evidence from a randomized controlled trial and large-scale real-world studies by Jianjie Xu, Zhuo Rachel Han, Xiangxi Lv, Lu Chen, Ningning Mao, Mengyu Miranda Gao, Hanyi Zhang, Yueqin Hu, Shaozheng Qin, James J. Gross, Zhanjun Zhang

“…E-mental health interventions offer promising population-level solutions, yet few are grounded in theory or tested on large samples. This study utilizes an innovative e-mental health intervention based on the Extended Process Model of Emotion Regulation and examines the effectiveness of this theory-based intervention across a randomized controlled trial (RCT, N = 187; Chinese Clinical Trial Registry: ChiCTR2400081964; registration date: March 18th, 2024) and two extensive real-world studies (N study 2 = 11,554, N study 3 = 44,018) conducted with adults in China. …”
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Digital subtraction analysis after application of silver diamine fluoride on early proximal caries lesions: a 12-month randomized controlled trial by Rinrada Pirompak, Chutima Trairatvorakul, Suchaya Pornprasertsuk-Damrongsri, Thipawan Tharapiwattananon, Pornkawee Charoenlarp, Ratichanok Nantanee

“…Two active non-cavitated proximal caries lesions in different quadrants of each participant were randomly sampled and allocated to a test (38% SDF) and a control group (deionized water). …”
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Impact of a Plant Sterol Food Supplement on Eryptotic and Associated Cardiometabolic Parameters: A Randomized Placebo-Controlled Trial in Statin-Treated Patients by Diego Miedes, Raquel Ortega-Luna, Sonia Broseta, Sergio Martínez-Hervás, Ángeles Álvarez-Ribelles, Víctor Collado-Díaz, Antonio Cilla, Amparo Alegría

“…Blood samples were extracted before (T0) and after (T1) a 6-week treatment, and erythrocytes were isolated for biochemical determination, phosphatidylserine externalization (EPHS), cell size and reduced glutathione (GSH) analyses, and endothelium adhesion evaluation. …”
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COMPARATIVE ANALYSIS OF EFFECTIVENESS AND SAFETY OF PHYTO- AND ANTIBIOTIC THERAPY OF ACUTE BRONCHITIS IN CHILDREN: RESULTS OF A MULTICENTER DOUBLE BLIND RANDOMIZED CLINICAL TRIAL by L. S. Namazova-Baranova, M. S. Kotlyarova, Yu. V. Rovenskaya, V. P. Vavilova, G. A. Novik, O. P. Kovtun, N. I. Aver'yanova, A. N. Galustyan, N. A. Il'enkova, A. I. Safina, Yu. V. Lobzin, M. A. Snovskaya

“…The level of procalcitonin (PCT) – a bacterial inflammation marker – was measured retrospectively in the blood samples of all the children obtained at inclusion to the study. …”
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Short-Term Effects of Kefir-Fermented Milk Consumption on Bone Mineral Density and Bone Metabolism in a Randomized Clinical Trial of Osteoporotic Patients. by Min-Yu Tu, Hsiao-Ling Chen, Yu-Tang Tung, Chao-Chih Kao, Fu-Chang Hu, Chuan-Mu Chen

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Investigating the effects of watson-based education on depressive symptoms, hope, and pain in cancer patients undergoing chemotherapy: a randomized controlled clinical trial by Fateme Rajabi, Mostafa Bijani, Mohammad Mehdi Naghizade, Leila Nikrouz

“…A total of 120 randomly selected patients were assigned to two intervention groups (n = 60) and a control group (n = 60). …”
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Urine TIMP2.IGFBP7 Reflects Kidney Injury After Moderate Volume Paracentesis in Patients With Ascites: A Randomized Control Study by Anuchit Suksamai, Sanpolpai Khaoprasert, Amnart Chaiprasert, Sakkarin Chirapongsathorn

“…Serial urine samples were analyzed for TIMP2. IGFBP7 concentration before and after paracentesis. …”
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Acute Effect of a Protein Supplement on Targeted Plasma Amino Acid Profile among Healthy Asian Indians: A Randomized Controlled Trial by Ammu Kurien, Nidhi Sharma, Madhavi Marathe, Nandan Joshi, Sumithra Selvam, Sarita Devi, Sucharita Sambashivaiah

“…In this double-blind, randomized, crossover study, 20 healthy Indian adults were randomized to receive the test protein supplement (treatment arm, n = 10) or placebo (control arm, n = 10) with milk, after overnight fasting. …”
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Effects of spinal versus general anesthesia on serum oxidative stress markers and cytokine release after abdominal hysterectomy: a non-randomized trial by Morteza Hashemian, Shahrzad Sahebdad-Khabisi, Zahra Honarvar, Zohreh Torabinejad, Hosein Taravati, Fatemeh Doost Mohammadi, Ladan Amirkhosravi

“…A single-blinded, non-randomized controlled trial was conducted on forty-two patients (American Society of Anesthesiologists (ASA) class I and II) undergoing abdominal hysterectomy. …”
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Druggable genome-wide Mendelian randomization integrating GWAS and eQTL/pQTL data identifies targets for lung squamous cell carcinoma by Shizhao Cheng, Hao Zhang, Zhenliang Shi, Daqiang Sun

“…Druggable genome-wide Mendelian randomization (MR) was conducted to discover LUSC-related targets using expression quantitative trait loci (eQTL) and protein QTL (pQTL) in the ieu_b_4953 dataset and finngen dataset. …”
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Effects of green coffee supplementation on paraoxonase-1 activity and malondialdehyde levels in Iranian women with polycystic ovary syndrome: a randomized clinical trial by Azam Ildarabadi, Marzieh Vahid-Dastjerdi, Mina Ghorbanpour, Ahmad Mousavi, Mehrnoush Meshkani, Mirsaeed Yekaninejad, Ahmad Saedisomeolia

“…Participants were randomly assigned to either the intervention or control group. …”
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Bioequivalence Study of Two Oral Methocarbamol Formulations in Healthy Subjects Under Fasting Conditions: A Randomized, Open-Label, Crossover Clinical Trial by Ana Ascaso-del-Rio, Paola Camargo-Mamani, Inmaculada Gilaberte, Mónica Díez-Hochleitner, Leonor Laredo-Velasco, Teresa Iglesias-Hernangómez, María Rosario Salas-Butrón, Laura Galán Caballero, Iván Alejandro Díaz-Rengifo, Carla Pérez-Ingidua, Emilio Vargas-Castrillón, Antonio Portolés-Pérez

“…To evaluate the pharmacokinetic profile, blood samples were collected at nineteen time points after dosing. …”
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Circuit training intervention for cognitive function, gut microbiota, and aging control: study protocol for a longitudinal, open-label randomized controlled trial by Keishi Soga, Michio Takahashi, Akari Uno, Takamitsu Sinada, Kentaro Oba, Keisei Kawashima, Yasuko Tatewaki, Taizen Nakase, Yasuyuki Taki

“…Methods A total of fifty-one participants will be randomly assigned to either the circuit training or waitlist control group. …”
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The Synergistic Effect of Intradialytic Concurrent Training and Melatonin Supplementation on Oxidative Stress and Inflammation in Hemodialysis Patients: A Double-Blind Randomized C... by Houssem Marzougui, Imen Ben Dhia, Ines Mezghani, Rami Maaloul, Salma Toumi, Khawla Kammoun, Mohamed Nejib Chaabouni, Fatma Ayadi, Mohamed Ben Hmida, Mouna Turki, Omar Hammouda

“…Methods: Thirty-two HD patients were randomly assigned to three groups: Exercise (EX)-MEL, EX-Placebo (PLA), and Control (C)-PLA. …”
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Effects of community action on animal vaccination uptake, antimicrobial usage, and farmers’ wellbeing in Ghana: study protocol for a cluster-randomized controlled trial by Francis Sena Nuvey, Günther Fink, Jan Hattendorf, Daniel T. Haydon, Gilbert Fokou, Kennedy Kwasi Addo, Jakob Zinsstag, Clemence Esse-Dibby, Bassirou Bonfoh

“…Clusters will be randomized with equal probability to treatment and control (23 communities each). …”
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SIGLEC1 has the potential to be an immune-related prognostic indicator in colon adenocarcinoma: a study based on transcriptomic data and Mendelian randomization analysis by Jue Gu, Yaxuan Wang, Hui Zhang, Haijuan Gu, Haixia Zhu

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Effects of Short-Term Traffic-Related Air Pollution Exposure on Nasal Microbiome in Young Healthy Adults: A Randomized Crossover Controlled Trial by Luwei Qin, Jingqi Pan, Demin Feng, Bingqing Yu, Shunyu Li, Xingyu Liu, Yuefei Jin, Shenshen Zhu, Weidong Wu, Wenjie Yang

“…Both groups were fully exposed to either a park environment or a road environment with high traffic volume. Nasal mucus samples were collected from the participants at the end of the trial, and then 16SrRNA sequencing was performed to analyze the differences in compositional structure and diversity of the nasal microbiome when volunteers were exposed to different levels of TRAP. …”
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Gut microbiota and metabolic responses to a 12-week caloric restriction combined with strength and HIIT training in patients with obesity: a randomized trial by Libuša Nechalová, Viktor Bielik, Ivan Hric, Miriam Babicová, Eva Baranovičová, Marián Grendár, Juraj Koška, Adela Penesová

“…Metagenomic sequencing of the V3-V4 region of the 16S rDNA gene from fecal samples allowed for gut microbiota classification. …”
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Can Milk-Derived Calcium Permeate Attenuate Loss of Bone Mineral Density in Postmenopausal Women? The 12 mo RENEW Randomized Intervention Study by Inge Tetens, Sidse Ida Ingemann Rasmussen, Mai Østerø Cramon, Caroline Filskov Petersen, Sadime Basak Kisi Kaki, Mette Friberg Hitz

“…Methods: A 12-month randomized controlled double-blinded multi-center intervention trial was conducted with healthy postmenopausal women with adequate vitamin D status. …”
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