Improvements in Glycemic Control With a Digital Diabetes Logbook: Secondary Analysis of a Randomized Controlled Trial Enriched by Observational, Real-World Data by Dominic Ehrmann, Bernhard Ruch, Michael Mitter, Johanna Kober, Norbert Hermanns, Vanessa Schäfer, Bernhard Kulzer, Stephan Silbermann

“…Long-term analyses revealed a sustained reduction in mean blood glucose over a 12-month period, with a mean decrease of –19.8 mg/dL (95% CI –21.8 to –17.9; P<.001) after 12 months of app use in the total RWD sample. ConclusionsThe secondary analysis of the RCT demonstrated a significant increase in the likelihood of achieving optimal glycemic control after 3 months of using the mySugr logbook. …”
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Comparative effects of kinesiotaping with and without combined chain exercises on pain, range of motion, and quality of life in knee osteoarthritis: a randomized controlled trial by Sobia Maqbool, Hina Gul, Janisar Zainab, Rida Mustafa

“…Thirty-eight patients with Grade II knee OA (Kellgren and Lawrence classification) aged 40–60 years were recruited using a convenience sampling technique and allocated into two groups via the lottery method. …”
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Oral microbiome diversity and composition before and after chemotherapy treatment in pediatric oncology patients by Egle Immonen, Lauri Paulamäki, Hannaleena Piippo, Atte Nikkilä, Liisa Aine, Timo Peltomäki, Olli Lohi, Mataleena Parikka

“…Mucosal swab samples were collected before and after chemotherapy. …”
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Effect of family-centered interventions on self-efficacy of family of patients with low consciousness admitted the intensive care units: A randomized controlled trial by Hadis Biranvand, Mehdi Birjandi, Fateme goudarzi, Heshmatolah Heydari

“…Seventy family members of patients were selected by convenience sampling and were assigned to the intervention (n=28) and control (n=28) groups by stratified random blocks. …”
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Efficacy of hemostasis and gingival retraction of Merocel strip compared with conventional retraction cord utilizing digital gypsum model: a randomized controlled trial by Leen Dannan, Mawia Karkoutly, Jihad Abou Nassar

“…The sample consisted of 122 abutments that were randomly divided into two groups. …”
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Effect of Remimazolam and Propofol on Blood Glucose and Serum Inflammatory Markers in Patients with Type 2 Diabetes: A Clinical Trial with Prospective Randomized Control by Sang Hun Kim, Sang Min Yoon, Ji Hye Ahn, Yoon Ji Choi

“…Seventy-four diabetic patients undergoing general anesthesia were randomly assigned to receive either remimazolam or propofol. …”
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Efficacy of brief cognitive behavior therapy in improving symptoms, functioning, and adherence to treatment in patients with bipolar disorder in remission: A randomized control stu... by Seema Nambiar, Manjula Munivenkatappa, Shyam Sundar Arumugham

“…The sample consisted of 30 patients each in the intervention and Treatment As Usual (TAU) groups selected from the outpatient services of a tertiary mental health hospital. …”
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The effect of video-assisted teaching on nursing students'practice skills and anxiety levels in Range of Motion (ROM) exercises: a randomized controlled study by Seçil Erden Melikoğlu, Burcu Demircan, Yasemin Kıyak Yorulmaz

“…Methods The study sample consisted of 72 first-year nursing students enrolled in the Fundamentals of Nursing course at a university in Istanbul, Turkey. …”
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Effectiveness of face to face and virtual education to promote breast self-examination based on the theory of planned behavior: a randomized controlled trial study by Halime Cheraghalizadeh, Hajar Adib-Rad, Hajar Pasha, Mohammad Chehrazi, Fatemeh Nasiri‑Amiri, Shabnam Omidvar

“…Participants were selected using a random sampling method and were randomly assigned to three groups of 80 each (face to face, virtual, and control). …”
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Bioequivalence Analysis of Ondansetron Hydrochloride Tablets in Healthy Chinese Subjects: A Randomized, Open-Label, Two-Period Crossover Phase I Study by Caiyun Jia, Na Zhao, Haojing Song, Yiting Hu, Yufang Xu, Caihui Guo, Wanjun Bai, Zhanjun Dong

“…Results The geometric mean ratio (GMR) of the maximum observed concentration (C max), the area under the plasma concentration‒time curve (AUC) from time zero to the last sampling time (AUC0–t ), and the AUC from time zero to infinity (AUC0–∞) from the test/reference formulation under fasting conditions were 90.50, 90.43, and 90.25, respectively. …”
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Effects of multisystem exercises on balance, postural stability, mobility, walking speed, and pain in patients with diabetic peripheral neuropathy: a randomized controlled trial by Sidra Khurshid, Aruba Saeed, Muhammad Kashif, Aniqa Nasreen, Huma Riaz

“…A total of 50 participants who met the inclusion criteria were recruited using the nonprobability convenience sampling technique. They were randomly assigned to either a multisystem physical exercise (MPE) group (n = 26) and a conventional exercise group (n = 24). …”
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The effect of patient-centered empowerment program through telenursing on self-management in people with multiple sclerosis: a double-blinded randomized clinical trial by Fateme Bayat, Reza Negarandeh, Shahzad Pashaeypoor

“…Methods The present study was a double-blinded, randomized clinical trial conducted on 90 PwMS attending MS Society using a convenience sampling method with random block allocation. …”
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Exploring the causal role of pathogen-derived antibodies in major urinary and kidney diseases: Insights from generalized summary data-based Mendelian randomization by Haoxiang Huang, Bohong Chen, Cong Feng, Wei Chen, Dapeng Wu

“…This study employs Generalized Summary data-based Mendelian Randomization (GSMR) to explore causal relationships between pathogen-derived antibodies and major urinary and kidney diseases.We conducted a two-sample MR analysis using summary statistics from large-scale Genome-Wide Association Studies (GWAS) to assess associations between 46 pathogen-specific antibodies and seven urinary system diseases. …”
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Autologous fat transplantation prior to permanent expander implant breast reconstruction enhances the outcome after two years: a randomized controlled trial by Anna Lindegren, Inkeri Schultz, Åsa Edsander-Nord, Jacinth Yan, Marie Wickman

“…They also had higher increase in satisfaction with breasts, psychosocial well-being, and sexual well-being when comparing baseline with 2 years postoperatively. This randomized controlled trial indicates benefits of AFT prior to breast reconstruction with expanders, especially on patient reported outcome even if the study sample is small. …”
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Causal relationships between gut microbiota and urothelial carcinoma mediated by inflammatory cytokines and blood cell traits identified through Mendelian randomization analysis by Xipeng Wu, Wenda Zou, Ziwei Liu

“…This study aimed to investigate the causal relationship between gut microbiota and three types of urothelial carcinoma (renal pelvic cancer [RPC], urothelial carcinoma [UC], and bladder cancer [BC]), and to explore potential underlying mechanisms. Methods Two-sample Mendelian randomization (MR) analysis was conducted using GWAS data to identify gut microbiota-associated SNPs and evaluate their causal effects on the three cancers. …”
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Genetic insights and therapeutic avenues: unraveling the role of polyunsaturated fatty acids as mediators between hypothyroidism and Von Willebrand disease through Mendelian random... by Wenting Zhou, Rui He, Ruwei Ou

“…In this study, we used a Mendelian randomization study to analyze the causal relationship between Hypothyroidism and VWD and to investigate whether polyunsaturated fatty acids mediate the effects of Hypothyroidism on VWD.MethodsUsing a large publicly available genome-wide association study of predominantly European ancestry to obtain data on Hypothyroidism, VWD, and PUFA, we conducted a two-sample Mendelian randomization study to assess the causal relationship between Hypothyroidism and VWD and assess the potential role of Polyunsaturated fatty acids in mediating the causal pathway between Hypothyroidism and VWD. …”
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Effects of high-intensity exercise on rehabilitation of patients after stroke: a systematic review and meta-analysis of randomized controlled trials with high quality by Shuang Li, Yuchang Dou, Hong Li

“…RCTs with sample size of ≥50 individuals were included. Primary outcomes assessed were the Six-Minute Walking Test (6MWT), Ten-Meter Walk Test (10MWT), VO2peak, Berg Balance Scale (BBS), Timed Up and Go test (TUG), and Montreal Cognitive Assessment (MoCA). …”
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High-concentrated platelet-rich plasma (PRP) versus placebo in osteoarthritis in the thumb base: study protocol for an assessor-blinded randomized controlled trial by Johanna von Kieseritzky, Maria Wilcke

“…With a planned sample size of 90 patients recruited from the Department of Hand Surgery at Södersjukhuset, Stockholm, the study will assess pain relief and functional improvement at 3, 6, and 12 months post-injection. …”
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A comparative study of machine learning algorithms for fall detection in technology-based healthcare system: Analyzing SVM, KNN, decision tree, random forest, LSTM, and CNN by Afuan Lasmedi, Isnanto R. Rizal

“…The research utilizes a dataset consisting of 1,428 training samples and 573 testing samples, evaluated using a 10-fold cross-validation technique. …”
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Effects of transcranial direct current stimulation (tDCS) associated with balance training in individuals with Parkinson's: Study protocol for a randomized clinical trial by Raynara Fonseca dos Santos, Guilherme Peixoto Tinoco Areas, Fernando Zanela da Silva Areas, Pedro Porto Alegre Baptista, Ayrles Silva Gonçalves Barbosa Mendonça, Renato Campos Freire Junior

“…In the PG, tDCS was applied in sham mode, with the same electrode positioning and the same number of sessions as the EG. The sample compared 34 individuals with PD (EG: 17; PG: 17).Cerebellar tDCS associated with balance training may help improve postural control and balance in walkers with Parkinson's Disease. …”
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