Effect of immunonutrition during concurrent chemoradiotherapy on acute oral mucositis in head and neck cancer patients: A prospective randomized study. by Pooriwat Muangwong, Tharatorn Tungkasamit, Vatanyu Samakgarn, Ausareeya Chumachote, Kittikun Kittidachanan, Imjai Chitapanarux

“…Further research with larger sample sizes, compliance monitoring, and optimized supplementation protocols is warranted to better understand the potential benefits of IN.…”
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Comparison of an AI Chatbot With a Nurse Hotline in Reducing Anxiety and Depression Levels in the General Population: Pilot Randomized Controlled Trial by Chen Chen, Kok Tai Lam, Ka Man Yip, Hung Kwan So, Terry Yat Sang Lum, Ian Chi Kei Wong, Jason C Yam, Celine Sze Ling Chui, Patrick Ip

“…MethodsThis study was a pilot randomized controlled trial conducted from October 2022 to March 2023, involving 124 participants allocated randomly (1:1 ratio) into the AI chatbot and nurse hotline groups. …”
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Taurolidine lock solutions for the prevention of catheter-related bloodstream infections: a systematic review and meta-analysis of randomized controlled trials. by Yong Liu, An-Qiang Zhang, Lin Cao, Hong-Tao Xia, Jun-Jie Ma

“…Data were combined using random-effects models owing to significant clinical heterogeneity.…”
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A daily positive work reflection intervention for psychological distress among Chinese nurses: a pilot randomized controlled trial by Li Zhang, Jian Xiao, Anao Zhang, Hui Zhang

“…The study used a convenience sample which led to a concern of external generalizability, and the study had limited evaluation of long-term change.…”
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The Effect of Educational Religious Intervention on Improving Life Expectancy in Cancer Patients Undergoing Chemotherapy: A Randomized Controlled Clinical Trial by Mehran Naghibeiranvand, Razia Mohseni, Ghazal Shafieian

“…Materials and Methods: The present clinical trial study was conducted on 128 patients with cancer undergoing chemotherapy referred to the oncology unit of a teaching hospital in Khorramabad, Iran. After selecting the sample size, the patients were randomly divided into intervention and control groups. …”
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Acute Effects of Dry Needling on Myofascial Trigger Points in the Triceps Surae of Ballet Dancers: A Pilot Randomized Controlled Trial by Jennifer A Janowski, Deanna M L Phelan-Smith, Maria N Kroat Brady, Kelsey L Michels, Alexandra H Timm, Nicole M Boucher, Kedron D Casteen, David Village, Mark D Sleeper

“…. # Study Design Randomized, double-blinded pilot study # Methods Professional ballet dancers that fit inclusion and exclusion criteria (n=11) were randomly assigned to an experimental or control group. …”
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The impact of lymphocyte count on male erectile dysfunction with clinical validations and its potential metabolic mechanisms through mendelian randomization analysis by Haoyang Dong, Yong Liu, Dong Di, Tingsong Bian

“…This article uses Mendelian randomization (MR) to analyze the causal relationship between clinical indicators and ED, and explores the potential metabolic mechanisms involved.Method Two-sample MR analysis was performed to analyze the causal relationships between 1,400 metabolites and clinical data and ED for revealing its potential metabolic mechanisms using GWAS (Genome-wide association studies) data. …”
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The association between primary frozen shoulder and serum lipids may be overestimated: evidence based on retrospective observational studies and Mendelian randomization by Yongchao Zhang, Wenhao Fan, Yichang Wang, Tengjing Dong, Deding Liu, Yiming Shao

“…We investigated the association between serum lipids and primary frozen shoulder by retrospective analysis and two-sample Mendelian randomization (MR) methods.MethodsThis retrospective observational study included 284 patients with primary frozen shoulder diagnosed from October 2020 to October 2023 at four centers as the experimental group. …”
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Effects of Intrinsic Foot Muscle Training in Improving Stability in Multiple Sclerosis Patients: A Single-Blind Randomized Clinical Trial by Daniel García-García, Jorge Juan Alvarado-Omenat, Rocío Llamas-Ramos, Marta Morais-Quintanilla, Inés Llamas-Ramos

“…<b>Methodology</b>: A randomized single-blind clinical trial was conducted using a sample of multiple sclerosis patients divided into a control group (CG) and an intervention group (IG). …”
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Maternal smoking around birth as a risk factor for offspring chronic obstructive pulmonary disease: Evidence from Mendelian randomization by Qiliang Jian, Huyan Huo, Fangxiang Mu, Fang Wang

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At-Home Immersive Virtual Reality Exergames to Reduce Cardiometabolic Risk Among Office Workers: Protocol for a Randomized Controlled Trial by Jing Zhao, Akitomo Yasunaga, Andrew T Kaczynski, Hyuntae Park, Yufeng Luo, Jiuling Li, Ai Shibata, Kaori Ishii, Shohei Yano, Koichiro Oka, Mohammad Javad Koohsari

“…A total of 120 Chinese office workers, engaging in less than 150 minutes per week of moderate to vigorous intensity physical activity, will be recruited via a convenience sampling method. The participants, who will be tested over a 12-week period, will be randomly assigned to one of three groups: (1) the VR exergame intervention group, (2) the regular physical activity control group, and (3) the nonexercise control group. …”
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Missingness matters: a secondary analysis of thromboelastography measurements from a recent prehospital randomized tranexamic acid clinical trial by Bellal Joseph, Raminder Nirula, Brian J Eastridge, Jason L Sperry, Joshua B Brown, Matthew D Neal, Gary A Vercruysse, Jack K Donohue, Nidhi Iyanna, John M Lorence, Frances X Guyette, Terence O'Keeffe

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The modular approach to therapy for youths with anxiety, depression, trauma, and conduct problems (MATCH): results from the Norwegian randomized-controlled trial by Silje S. Hukkelberg, Torbjørn Torsheim, Kristin Berg Nordahl, Görel E. Bringedal, Sivarajan Rajah, Kristine Amlund Hagen, John Kjøbli, Kristian Rognstad, Ana M. Ugueto, Sarah Kate Bearman, John Weisz

“…MATCH has, however, never been evaluated in a Nordic context, and the present study aimed to fill this gap. Methods A sample of 121 Norwegian youths (M age = 9.83, 58.7% boys) was randomly assigned to MATCH (n = 73) or treatment as usual (TAU, n = 48). …”
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The effects of mediterranean and Persian diet on sexual function and semen parameters quality among infertile men: a randomized controlled trial by Ali Ghasemi, Amir Mohammad Jaladat, Mohammad Hossein Sharifi, Ali Tavakoli, Haleh Ghaem, Abdolreza Haghpanah

“…Further studies with larger sample sizes and longer durations are needed for conclusive results.…”
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Diet and Physical Activity Intervention in Normal Weight Obesity Population Base on Smartphone App: Protocol for a Randomized Controlled Trial by Liu G, Yang K, Wang C, Yang J

“…The secondary outcomes include changes in measures of anthropometry, blood glucose, insulin, lipids and uric acid between the baseline and 12 weeks of intervention. A sample size of 200 subjects with normal BMI and glucose abnormality confirmed by oral glucose tolerance test will be recruited. …”
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Movimente program: effectiveness and moderators of a cluster-randomized controlled trial on self-reported physical activity among Brazilian adolescents by Jaqueline Aragoni da Silva, Kelly Samara da Silva, Bruno Gonçalves Galdino da Costa, Marcus Vinicius Veber Lopes, Jo Salmon

“…Design The Movimente Program was a cluster randomized controlled trial conducted at six elementary schools in southern Brazil in 2017. …”
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Comparative study of cabergoline and hydroxychloroquine to prevent ovarian hyperstimulation syndrome (OHSS) in PCOS patients: a pilot randomized clinical trial by Elnaz Salari, Negar Ajabi Ardehjani, Ladan Kashani, Kasra Jafari, Ashraf Moini

“…Materials and methods This double-blind, parallel, and randomized clinical trial was performed from April to June 2024. …”
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Increase in Strength After Multimodal Pain Management Concept in Patients with Cervical Radiculopathy—A Non-Randomized, Uncontrolled Clinical Trial by Gerd Zirkl, Jens Schaumburger, Matthias Gehentges, Moritz Kaiser

“…<i>Materials and Methods</i>: This non-randomized, uncontrolled, prospective clinical study initially included 35 patients, but 10 were excluded due to incomplete data, resulting in a final sample of 25 patients (14 women and 11 men, aged 42 to 84 years) with cervical radiculopathy who underwent a multimodal pain management program at a specialized orthopedic clinic. …”
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Feasibility, Acceptability, and Potential Effects of a Digital Oral Anticancer Agent Intervention: Protocol for a Pilot Randomized Controlled Trial by Saima Ahmed, Christine Maheu, Walter Gotlieb, Gerald Batist, Carmen G Loiselle

“…ResultsData collection was completed by December 2023 with a final sample size of 41. Results are expected to be published in 2025. …”
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Effects of Tactile Sensory Stimulation Training of the Trunk and Sole on Standing Balance Ability in Older Adults: A Randomized Controlled Trial by Toshiaki Tanaka, Yusuke Maeda, Takahiro Miura

“…Future studies should assess long-term effects and explore optimal training duration with larger sample sizes.…”
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