Albuminuria and Mental Illness Risk: Results From National Health and Nutrition Examination Survey 2005–2018 and Mendelian Randomization Analyses by Yangyang Wang, Sen Li

“…Weighted multivariable‐adjusted logistic regression, subgroup analysis, interaction tests, and restricted cubic spline (RCS) were conducted to assess the correlation between albuminuria and the risk of mental illness (depression). Subsequently, two‐sample Mendelian randomization analyses were performed to investigate the relationship between albuminuria and various mental illnesses (anxiety disorder, persistent delusional disorder, schizophrenia, schizotypal personality disorder, panic disorder, post‐traumatic stress disorder [PTSD], obsessive‐compulsive disorder, bipolar I disorder, bipolar II disorder, depression, autism, social anxiety disorder). …”
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Relation between the global burden of disease and randomized clinical trials conducted in Latin America published in the five leading medical journals. by Pablo Perel, J Jaime Miranda, Zulma Ortiz, Juan Pablo Casas

“…We analyzed the relationship between the global burden of disease and Randomized Clinical Trials (RCTs) conducted in Latin America that were published in the five leading medical journals.…”
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Polycystic ovary syndrome and risk of pregnancy-induced hypertension, gestational diabetes mellitus, and preeclampsia: a Bayesian Mendelian randomization study by Chunxiao Dang, Shaoting Wang, Pengfei Liu, Jinxing Liu, Xiao Yu, Leizuo Zhao, Tingting Xu, Mei Liu

“…Objective To investigate the causal association of polycystic ovary syndrome with pregnancy-induced hypertension (PIH), gestational diabetes mellitus (GDM), and preeclampsia (PEC) using two-sample Mendelian randomization (MR). Methods GWSA data from European populations were collected and causal analyses of PCOS (N = 113238) with PIH (N = 123579/118990), GDM (N = 123579/116363), and PEC (N = 123579/118291) were performed using mainly inverse variance weighted (IVW) method, along with Bayesian analysis to improve the accuracy of the results. …”
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The effect of biologically oriented and subgingival horizontal preparation techniques on periodontal health: A double-blind randomized controlled clinical trial by Alkhedhairi Mohammad, Shebin Abraham, Alarami Nada

“…The teeth were randomly allocated for the preparation techniques. …”
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Photobiomodulation Therapy Plus Usual Care Is Better than Usual Care Alone for Plantar Fasciitis: A Randomized Controlled Trial by Ann K Ketz, Juanita Anders, Judy Orina, Betty Garner, Misty Hull, Nicholas Koreerat, Jeff Sorensen, Candice Turner, James Johnson

“… # Study Design Prospective, randomized controlled clinical trial # Methods A convenience sample of adults with PF were randomly assigned to one of three groups: (1) usual care, (2) usual care plus nine doses of PBMT with 25W output power over three weeks, or (3) usual care plus nine doses of PBMT with 10W output power over three weeks. …”
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Ascertaining the Effectiveness of Strength-Aerobic Combined Exercise in Improving Body Composition among Obese Women: A Randomized Controlled Trial by Bhekti Lestari, Adi Pranoto, Agus Hariyanto, Ghana Firsta Yosika, Gigih Siantoro, Laily Mita Andriana, Raymond Ivano Avandi, Sherry Iris Zalillah, Eva Ferdita Yuhantini

“…The data analysis techniques used were the paired sample t-test, with a significance level of 95%. …”
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Impact of phone call intervention on glycemic control in diabetes patients: a systematic review and meta-analysis of randomized, controlled trials. by Naeti Suksomboon, Nalinee Poolsup, Yuu Lay Nge

“…However, telephone intervention may still have potential benefits especially for low-and middle-income countries; thus further large sample size and well-controlled studies are needed to evaluate the impact of the intervention.…”
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Investigating the effect of online narrative therapy on the genital self-image and sexual satisfaction of infertile women: a randomized controlled trial by Fatemeh Shahriari, Armin Firoozi, Marzieh Azizi, Narges Moslemyzadeh, Abolfazl Hossein Nataj, Soghra Khani

“…The present study aimed to determine the effect of online narrative therapy on the genital self-image and sexual satisfaction of infertile women. Methods This randomized controlled trial was conducted with 64 women with infertility, who were selected through the convenience sampling method from gynaecologists with infertility fellowship and family physician clinics. …”
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Distinct pathway-based effects of blood pressure and body mass index on cardiovascular traits: comparison of novel Mendelian randomization approaches by Genevieve M. Leyden, Maria K. Sobczyk, Tom G. Richardson, Tom R. Gaunt

“…Additionally, we assessed the likelihood that estimates observed for partitioned exposures could emerge by chance using random SNP sampling. Results Our pathway-partitioned findings suggest the causal relationship between systolic BP and heart disease is predominantly driven by vessel over renal pathways. …”
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Transcranial direct current stimulation associated with physical exercise can help smokers to quit smoking: a randomized controlled trial by Giselma Alcantara da Silva, Lucas Chagas Silva, Euclides Maurício Trindade Filho, Mayara Vieira Damasceno, Kátia Monte-Silva, Adriana Ximenes-da-Silva

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Efficiency of Repetitive Transcranial Direct Current Stimulation of the Dorsolateral Prefrontal Cortex in Disorders of Consciousness: A Randomized Sham-Controlled Study by Min Wu, Yamei Yu, Lunjie Luo, Yuehao Wu, Jian Gao, Xiangming Ye, Benyan Luo

“…However, future studies with large sample sizes are needed to confirm these findings. …”
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The Effect of Foot Reflexology Massage on Anxiety and Physiological Indices in Patients under CABG Surgery: A Randomized Placebo-Controlled Trial by Majid Pourshaikhian, Negar Pourvakhshoori, Mehri Shahidi, Saman Maroufizadeh, Mohammad Taghi Moghadamnia

“…Materials & Methods A sample of 120 patients who underwent CABG surgery was randomly assigned to three groups as follows: The intervention group (foot reflexology massage), the control group (no intervention), and the placebo group (superficial foot massage). …”
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Genetic evidence of bidirectional mendelian randomization study on the causality between gut microbiome and respiratory diseases contributes to gut-lung axis by Xiaoqing Zhou, Shuyan Shen, Zhen Wang

“…The causal link between the gut microbiome and respiratory illnesses was then estimated using a Two-sample Mendelian randomization (MR) analysis, including the inverse-variance weighted (IVW), weighted median, MR-Egger, simple mode, and weighted mode. …”
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Breakfast skipping is linked to a higher risk of major depressive disorder and the role of gut microbes: a mendelian randomization study by Xingzhi Guo, Wei Li, Chen Hou, Rui Li

“…Further efforts with a large sample size are warranted to clarify the findings.…”
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Advanced Practice Nurse Intervention Versus Usual Care for Hypertension Control: A Pilot Open‐Label Randomized Controlled Trial by Juliette Vay‐Demouy, Hélène Lelong, Jacques Blacher

“…The APN intervention consisted of an in‐depth therapeutic education and an assessment of therapeutic strategies with adjustments if needed. The study sample included 437 participants (n = 229 in the experimental group; n = 208 in the “usual care” group). …”
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Genetic Insights Into the Role of Cathepsins in Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis: Evidence From Mendelian Randomization Study by Yanhong Jiang, Wenhui Fan, Yaxin Li, Hua Xue

“…Methods We conducted a two‐sample bidirectional Mendelian randomization (MR) study using publicly available data from genome‐wide association study (GWAS) to assess the causal associations between 10 cathepsins and three neurodegenerative diseases, including AD, PD, and ALS. …”
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Efficacy of a theory-based and tailored mHealth intervention promoting walking behavior: a preliminary randomized controlled trial by Roberta Adorni, Francesco Zanatta, Silvia Serino, Maria Elide Vanutelli, Daniela Caso, Marco D’Addario, Patrizia Steca

“…This study evaluated the efficacy of an ad-hoc developed mobile health (mHealth) intervention, which adopts a theory-based and tailored communication approach and targets walking behavior change. A convenience sample of physically inactive adults (n = 193) participated in a 30-day randomized trial. …”
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Impact of an exercise program combined with dietary advice on avoiding insulin prescription in women with gestational diabetes: a randomized controlled trial by Michel Boulvain, Véronique Othenin-Girard, François R. Jornayvaz, Bengt Kayser

“…Low adherence to the intervention, a small sample size, and the short duration of the program may explain the lack of observed benefit. …”
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Educational attainment, body mass index, and smoking as mediators in kidney disease risk: a two-step Mendelian randomization study by Lei Zhang, Baiyu Feng, Zhiwen Liu, Yu Liu

“…This study aims to assess the causal relationship between EA and KD and quantify the mediation effects of modifiable risk factors using a Mendelian randomization (MR) approach.Methods We performed a two-sample MR analysis utilizing summary statistics from large-scale European genome-wide association studies (GWAS). …”
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Independent effects of mental health disorders on breast cancer and their mediating factors: evidence from NHANES and two-step Mendelian randomization by Kang Ma, Xueyan Mao, Hongkai Zhuang, Cheng Long, Bo Chen

“…The independent effects of depression, panic, and anxiety on BC were estimated through two-sample multivariable MR. Furthermore, 23 possible mediators of the connection were assessed and mediated proportions were computed using two-step MR. …”
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