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2701
Analyzing and predicting short-term substance use behaviors of persons who use drugs in the great plains of the U.S.
Published 2024-01-01“…All predictive models were evaluated by computing the (averaged) Area under the Receiver Operating Characteristic curve (AUROC) and Area under the Precision-Recall curve (AUPR) on multiple distinct sets of hold-out sample.…”
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2702
Porphyromonas gingivalis outer membrane vesicles augments proliferation and metastasis of oral squamous cell carcinoma cells
Published 2025-05-01“…The purpose of this study was to establish the clinical relationship between P. gingivalis and OSCC based on clinical samples. Further, the effect of P. gingivalis OMVs on OSCC was observed with cell model in vitro, and the possible molecular mechanism was discussed. …”
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2703
Exogenous TSG-6 treatment alleviates DSS-induced colitis in mice by modulating Pou2f3 and promoting tuft cells differentiation
Published 2025-04-01“…The effects of TSG-6 on colonic inflammation and intestinal barrier function were investigated. Label-free quantitative proteomic analysis was performed on intestinal samples to explore the mechanism and therapeutic target of TSG-6. …”
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2704
LC-MS/MS-Based Concurrent Quantification of Cannabidiol and Melatonin in Mouse Plasma to Elucidate Complex PK Interactions
Published 2024-11-01“…</i> Pharmacokinetic parameters were calculated using a non-compartmental model and analyzed to investigate the interactions of CBD with MT. …”
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2705
Assessment of polyvinylpyrrolidone vinyl acetate effect on quercetin properties in binary solid dispersion prepared by hot melt extrussion
Published 2025-03-01“…In order to study the mentioned problem, we decided to use quercetin as model compound with extremely low water solubility and dissolution in gastrointestinal (GI) tract media. …”
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2706
Increased Co-Expression of PD-L1 and CTLA-4 Predicts Poor Overall Survival in Patients with Acute Myeloid Leukemia Following Allogeneic Hematopoietic Stem Cell Transplantation
Published 2025-01-01“…This study aims to investigate the significance of the alteration of IC co-expression for evaluating the prognosis of AML patients following allogeneic hematopoietic stem cell transplantation (allo-HSCT).Patients and Methods: Quantitative real-time PCR (qRT-PCR) data of bone marrow (BM) samples from 62 de novo AML patients, including 37 patients who received allo-HSCT and 25 patients who received chemotherapy only, were used for prognostic analysis.Results: High expression of PD-1, PD-L1, PD-L2, CTLA-4, and LAG-3 was associated with poor overall survival (OS) in AML patients receiving allo-HSCT, while the expression levels of PD-1, PD-L2, CTLA-4, and LAG-3, other than PD-L1, were not significantly correlated with OS in AML patients receiving chemotherapy. …”
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2707
Identification Exploring the Mechanism and Clinical Validation of Mitochondrial Dynamics-Related Genes in Membranous Nephropathy Based on Mendelian Randomization Study and Bioinfor...
Published 2025-06-01“…A nomogram model exhibited exceptional diagnostic performance (area under the curve [AUC] = 1). …”
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2708
Multidimensional Comprehensive Evaluation Method for Sonar Detection Efficiency Based on Dynamic Spatiotemporal Interactions
Published 2025-06-01“…We introduce a Markov chain model to guide the Monte Carlo sampling; it helps to specify the uncertain situations by constructing a high-fidelity target motion trajectory database. …”
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2709
Screening of endoplasmic reticulum stress characteristic genes and immune infiltration manifestations in chronic obstructive pulmonary disease
Published 2024-07-01“…Immunoinfiltration analysis showed that COPD samples were highly correlated with a variety of immune cell infiltrations. …”
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2710
Kinetics Study of (Se80Te20)100–xCdx Glassy Alloy by Differential Thermal Analysis Using Non-Isothermal Technique
Published 2011-01-01“…A comparison of various quantitative methods to assess the level of stability of the glassy material in the above mentioned system is presented. …”
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2711
Advice on better utilization of validation data to adjust odds ratios for differential exposure misclassification (recall bias)
Published 2025-07-01“…Plummer M. rjags: Bayesian Graphical Models using MCMC. R package version 4-16 ed2024. 12. …”
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2712
Syntactic Analysis of Spatial Structure Characteristics of Traditional Villages Along the Yellow River in Western Shanxi Province
Published 2025-05-01“…Secondly, based on the angular segment analysis method, a cross-star model is constructed to explore the accessibility and structural degree of the foreground and background networks of the village samples. …”
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2713
AFF3 is a Prognostic Biomarker Correlated with Immune Infiltrates in Triple-Negative Breast Cancer
Published 2023-08-01“…Twenty-five paired primary TNBC tumor tissues and adjacent non-tumorous tissues were collected from patients at Jiangxi Cancer Hospital (Nanchang, China). Quantitative real-time polymerase chain reaction (qRT-PCR) and western blotting were performed to assess the mRNA and protein expression of AFF3 in these samples. …”
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2714
Sensitivity analysis of the lithospheric magnetic field at satellite altitude: the effects of the inducing field and the shape of the magnetic lithosphere
Published 2025-05-01“…We expect the formulae and conclusions of this study to be a valuable tool for the quantitative interpretation of the Earth’s global lithospheric magnetic field, through an inverse or forward modelling approach.…”
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2715
Identification and validation of key biomarkers associated with immune and oxidative stress for preeclampsia by WGCNA and machine learning
Published 2025-03-01“…Diagnostic potential of candidate biomarkers was quantitatively assessed through ROC curve modeling. Additionally, we constructed a miRNA - gene regulatory network for the identified diagnostic genes and predicted potential candidate drugs. …”
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2716
Soil quality assessment of a Semi-arid region using fuzzy logic and analytic hierarchy process technique: case study of Semnan Province's Telobin
Published 2017-09-01“…Soil samples were analyzed for its physical and chemical soil properties and incorporated to topographical characteristics for further analysis. …”
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2717
Analysis of the distribution and persistence of organophosphorus pesticides malathion and diazinon in herbal plants
Published 2024-09-01“…Stinging nettle, that grows everywhere, exclusively cultivated marigolds, and valerian were selected as model plants. All of the plants were divided into three equal groups. …”
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2718
Internet and telephone intervention to support patients discontinuing long-term antidepressants in primary care: the REDUCE research programme including RCT
Published 2025-07-01“…The results may not generalise to an unselected sample of people on long-term antidepressants, including people at greater risk of relapse. …”
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2719
Radiomics-Based Machine Learning for Determining Amplification Status in Childhood Neuroblastoma: A Systematic Review and Meta-Analysis
Published 2025-07-01“…This systematic review and meta-analysis aimed to quantitatively evaluate the diagnostic accuracy of radiomics-based machine learning models for determining MYCN amplification in neuroblastoma and to critically assess the methodological quality of the included studies. …”
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2720
Optimization of composition and technology for tablets containing aspen bark extract
Published 2015-04-01“…The relationship between the studied factors and parameters of tablets’ regression models has been described. As a result tablets containing aspen bark extractwith mentioned above formula match necessary pharmaco-technological parameters of State Pharmacopoeia of Ukraine. …”
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