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2541
NSUN2 knockdown ameliorates hepatic glucose and lipid metabolism disorders in type 2 diabetes mellitus through the Inhibition of ACSL6 m5C methylation
Published 2025-07-01“…Quantitative real-time PCR was performed to assess m5C-associated gene expression in HFD-fed mice and NSUN2 levels in clinical samples. …”
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2542
Uncovering glycolysis-driven molecular subtypes in diabetic nephropathy: a WGCNA and machine learning approach for diagnostic precision
Published 2025-01-01“…An unsupervised consensus clustering of DN samples from the same dataset was conducted based on differentially expressed GRGs. …”
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2543
Fitting Quality of NMR Relaxation Data to Differentiate Asphalt Binders
Published 2024-10-01“…Two batches of PG 64-22 asphalt binder, along with samples of PG 76-22 and 94-10 binders, were investigated. …”
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2544
Inflammatory breast cancer: High incidence of GCC haplotypes (−1082A/G, −819T/C, and −592A/C) in the interleukin-10 gene promoter correlates with over-expression of interleukin-10...
Published 2017-07-01“…We found co-dominant effect as the best inheritance model (in the three studied single nucleotide polymorphisms in non–inflammatory breast cancer and inflammatory breast cancer samples), and we didn’t identify any association between single nucleotide polymorphisms genotypes and breast cancer prognostic factors. …”
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2545
Understanding Debt Dynamics: The Role of Financial Literacy, Income, and Lifestyle with Gender as a Moderating Variable
Published 2024-12-01“…The population in this research is all people in the province of West Java. Samples were collected using the Accidental Sampling technique, and statistical testing tools using Structural Equation Modeling (SEM) with SmartPLS software. …”
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2546
The CD163 + tissue-infiltrating macrophages regulate ferroptosis in thyroid-associated ophthalmopathy orbital fibroblasts via the TGF-β/Smad2/3 signaling pathway
Published 2025-04-01“…Single-cell sequencing of six human tissue samples further analyzed changes in cellular subpopulations within the TAO microenvironment.Additionally, a co-culture model of CD163 + macrophages and TAO orbital fibroblasts, along with an in vitro TGF-β1-induced orbital fibroblast (OF) model, was constructed to validate the role of the TGF-β1/SMAD2/3 axis in ferroptosis regulation. …”
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2547
Blood and urine early treatment response biomarkers in HIV-associated disseminated tuberculosis
Published 2025-04-01“…Objectives: We describe the changes in bacillary load during early treatment using quantitative and semi-quantitative measures of Mycobacterium tuberculosis in blood and urine. …”
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2548
A comparative analysis of service quality and student perceptions in Kyrgyzstan’s higher education institutions
Published 2025-12-01“…This study investigates the quality of higher education through student satisfaction, utilizing the ServQual model to assess gaps between student expectations and perceptions of educational services. …”
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2549
Dual U-Net with multi-task attention for automated eyelid curvature quantification
Published 2025-07-01“…In segmentation tasks, the proposed AtDU-Net model achieved an IoU of 0.979 and a Dice coefficient of 0.989. …”
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2550
Determination of chlorothalonil and its metabolite 4-hydroxychlorothalonil residues in animal-derived food by ultra-high performance liquid chromatography-tandem mass spectrometry
Published 2024-09-01“…The anion multiple reaction monitoring model (MRM) of atmospheric pressure chemical ionization source (APCI) was used for the determination, and the matrix matching external standard method was used for quantitative determination.ResultsThe linear relationships of chlorothalonil and 4-hydroxychlorothalonil were good in the range of 5~500 μg/L, and the limits of quantitation were 0.005 mg/kg. …”
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2551
Irisin: An influential perspective on the protective effect of metformin on aortic and cardiac aging in rats
Published 2025-03-01“…The predictive value of irisin for the effects of metformin on cardiac and aortic aging in an aged rat model was evaluated by quantitative and histological confirmation. …”
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2552
The Factors Affecting the Development of Advertising through Social Media to Influence the Sport Product Customers’ Behavior Intentions
Published 2024-02-01“…Sampling was also purposeful and accessible. The study tool was a semi-structured interview and a researcher-made questionnaire derived. …”
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2553
The potential role of biomarkers CD28 and PF4 in the pathogenesis of idiopathic pulmonary fibrosis and their impact on the prognosis: an immune microenvironment analysis
Published 2025-06-01“…Subsequently, key module genes closely associated with IPF samples were selected using Weighted Gene Co-expression Network Analysis (WGCNA). …”
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2554
Research on Intelligent Diagnosis of Corrosion in the Operation and Maintenance Stage of Steel Structure Engineering Based on U-Net Attention
Published 2024-12-01“…Leveraging a dataset of steel plate corrosion images with known grades, we train an Inception v3 corrosion classification model. Transfer learning techniques are then applied to determine the corrosion grade of each filtered window, culminating in a weighted average to estimate the overall corrosion grade of the target component. …”
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2555
Impact of Social Structure Characteristics of High School and University Students Playing Fencing Sports on Collective Efficacy and Goal Orientation
Published 2022-04-01“…This study uses a descriptive (survey) research model based on quantitative observation. The research is limited to fencing athletes who are active in licensed, high school, and university education in 2020-2021 Academic Year. …”
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2556
Types of Attributive Constructions in Middle English Poetry
Published 2025-04-01“…The most frequent type of attributive construction is the model in which the role of the attribute is performed by the adjective (37 %). …”
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2557
ASSERTIVE BEHAVIOUR AND SELF ESTEEM AMONG ADOLESCENT GIRLS
Published 2017-01-01“…To study the effectiveness of assertiveness training on self esteem and assertive behavior among adolescent girls of selected government schools, investigator developed a conceptual framework based on the Nola Pander's Health Promotion Model. The research approach adopted for the present study is a quantitative approach and the design selected was a quasi-experimental design (non equivalent pre test post test control group). …”
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2558
Medical narrative competency, empathy, and self-efficacy among senior medical undergraduates in China: a cross-sectional analysis
Published 2025-07-01“…Methods This study employed a quantitative cross-sectional design and enrolled 434 full-time senior medical undergraduates at a university in Chongqing, China, through convenience sampling. …”
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2559
Epimedin B protects against bone loss and inflammation in diabetic osteoporosis rats by regulating OPG/RANKL pathway
Published 2025-04-01“…In this study, our goal is to investigate the functions and underlying mechanisms of EB in the progression of DOP. Methods A DOP rat model was established via a high-fat diet combined with intraperitoneal injection of streptozotocin (STZ). …”
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2560
Driving Sustainability Performance in Hotels Through Green Digital Leadership and Circular Economy: The Moderating Role of Hotel Green Efficacy
Published 2025-05-01“…Participants were recruited using a stratified sampling method to ensure sectoral representation. …”
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