Quality of Life in Wilson’s Disease: A Systematic Literature Review by Chakrapani Balijepalli, Kevin Yan, Lakshmi Gullapalli, Stephane Barakat, Helene Chevrou-Severac, Eric Druyts

“…**Discussion:** Although our understanding of the underlying pathophysiology of WD has advanced, and novel therapeutics are on the horizon, our understanding of how WD affects overall QOL remains limited. …”
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Resistant stomach ulcer at Cushing disease: clinical case by N. V. Novozhilov, Yu. O. Shulpekoa, S. V. Mironov, Ye. K. Baranskaya, A. A. Sheptulin, V. T. Ivashkin

“…Hypercorticoidism is one of the causes of treatment-resistant stomach ulcers that is due to increase in gastric secretion and depression of collagen formation under the effect of hydrocortisone. Since 2009 we follow up the patient (female, 47 years old) who for the first time addressed to the doctor with complaints of pain and muscle weakness, mainly — of lower extremities, and also hip, ankle joints pain, which essentially complicated locomotion capacity. …”
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Scoping review: relationship between glucose tolerance and pulmonary decline in cystic fibrosis by Raina Tomoda, Deborah Jane Holmes-Walker

“…For CGM, four studies found inverse associations between %FEV1 and percent predicted forced vital capacity (%FVC) and the number of glucose measurements ≥ 11.0 mmol/L, the percentage of time spent with glucose > 7.8 mmol/L, or the area under the curve > 7.8 mmol/L. Intermediate OGTT values and CGM metrics are associated with lung function decline in CF without diabetes. …”
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Plasma miRNAs in polycystic ovary syndrome drive endometrial cancer progression: insights into molecular pathways and therapeutic targets by Xuedan Lai, Ling Wu, Peihong Lin, Lijiao You, Jianwen Ye

“…Abstract Polycystic ovary syndrome (PCOS) is a known risk factor for uterine endometrial cancer (UCEC), but its underlying mechanisms remain unclear. MicroRNAs (miRNAs) could provide insights into these mechanisms and reveal potential therapeutic targets. …”
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Exploring the epidemiological impact of attractive targeted sugar bait against malaria in combination with standard malaria control by Nima R. Moghaddas, Mohamed M. Traore, Gunter C. Müller, Joseph Wagman, Javan Chanda, Julian Entwistle, Christen M. Fornadel, Thomas S. Churcher

“…Nevertheless, the uncertainty in the relationship between the observed dyed fraction and the true bait-feeding rate, and the underlying biology of mosquito sugar-feeding means that the epidemiological benefit of this new possible intervention remains unclear.…”
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Acute hepatitis of non-specified etiology by Ye. V. Tsyganova, O. O. Znoyko, N. D. Yushchuk, K. R. Dudina, M. G. Isagulyants, N. V. Petrakova, T. V. Petrova, M. I. Mikhaylov

“…Investigation of patients with acute hepatitis of non-specified etiology included clinical, epidemiologic, routine laboratory, serological methods; molecular biological method (RNA of hepatitis A, C, Е, G viruses; DNA of hepatitis B virus, TTV, CMV, EBV, HHV of 1, 2, 6 and 8 types, PV B-19, NV-f – qualitative analysis); method of immunofluorescence (assessment of antimitochondrial and antinuclear antibodies); immunologic methods (laboratory diagnostic methods) – independent assessment of specific antibodies for individual HCV antigens spectrum, including structural and unstructural proteins and compound peptides, representing the whole HCV polyprotein (overall 38 antigens: 34 HCV antigens and 4 control antigens) in blood serum by EIA method; investigation of Т-cellular immune response to HCV antigens by blast-cell lymphocytes transformation method under stimulation by HCV antigens with quantitative evaluation of cytokine secretion; instrumental method – ultrasound investigation of abdominal organs.Conclusions. …”
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Multi-omics reveals that ST6GAL1 promotes colorectal cancer progression through LGALS3BP sialylation by Yuanchao Shi, Zhenzhong Pan, Jingwei Duan, Zexing Wang, Yiliang Fang, Bo Tang, Quanlin Guan

“… ST6 β-galactoside α2,6-sialyltransferase 1 (ST6GAL1), a crucial enzyme for tumor-associated sialic acid modification, has been reported to positively correlate with colorectal cancer (CRC) tumorigenesis; however, the underlying mechanism remains unclear. To elucidate the protumor mechanisms of ST6GAL1, we performed transcriptomic and N-glycoproteomic analyses and in vitro assays. …”
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How prepared is Nigeria digital payment for health workers? A landscape analysis by Folashayo Peter Adeniji, David Ayobami Adewole, Segun Bello, Elizabeth Ekirapa, Juliet Aweko, Vincent Michael Kiberu, Charles Opio, Peter Waiswa, Olufunmilayo Ibitola Fawole

“…Other incentives for digitization of payments were: availability of credible financial institutions, improved financial accountability and transparency, previous experience of under-payment or non-payment of end beneficiaries, to avoid delays in payment and ensure timely retirement of funds. …”
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Associations between nutrient intake and osteoarthritis based on NHANES 1999 to 2018 cross sectional study by Xiaofeng Lv, Xinmin Deng, Rui Lai, Shanshan Liu, Zihao Zou, Xuechun Dai, Yalan Luo, Jian Luo, Ying Li

“…Further research is needed to confirm these findings and clarify the underlying mechanisms.…”
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Perspectives of substance use disorder counselors on the benefits and drawbacks of medications for opioid use disorder by Nicholas C. Cardamone, Rebecca E. Stewart, Kyle M. Kampman, Steven C. Marcus

“…Methods From June to December 2021, we surveyed counselors from publicly-funded SUD treatment agencies under a municipality-wide mandate to offer MOUD to all clients with OUD. …”
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Microbial dysbiosis in periodontitis and peri-implantitis: pathogenesis, immune responses, and therapeutic by Ziwei Cui, Peng Wang, Weiyue Gao

“…Further research is needed to clarify the mechanisms underlying the transition from peri-implant mucositis to peri-implantitis and to optimize prevention and treatment approaches, considering the complex interactions between the microbiome and host immunity.…”
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Cirrhotic cardiomyopathy by S. N. Mammayev, A. M. Karimova, T. E. Il’yasova, A. Sh. Khasayev

“…Disorder of signal conduction from β-adrenoreceptors, calcium channels receptors, decrease of cardiomyocyte membrane fluidity, increase of nitric oxide and carbon monoxide synthesis, elevation of endocannabinoid system activity and many other changes observed at LC, cause development of complex of structural and functional disorders in myocardium, underlying development of CCM. Results of numerous studies showed suppression of contractile response to action of various physiological and pharmacological stimuli, and disorder of diastolic function of the heart, development of electrophysiological, structural and biochemical changes at LC irrespective of its origin. …”
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Efficiency comparison of natural coagulants (Cactus pads and Moringa seeds) for treating textile wastewater (in the case of Kombolcha textile industry) by Getahun Demeke Worku, Shimeles Nigussie Abate

“…The ideal parameters were pH 4, 5 g/l of coagulant, 40 min of mixing time, 2 min of fast mixing at 100 rpm, 40 min of gradual mixing at 40 rpm, and 30 min of settling time. Under these ideal circumstances, 82.33 Moreover, cactus pad powder reduced turbidity by 53.16 %, TDS by 97 %, BOD by 58.75 %, COD by 25.37 %, Conductivity by 60 %, and TSS by 56.33 %. …”
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Preliminary Evaluation of Some Engineering Geological Properties of Soils in the New Yenagoa Town, Bayelsa State, Central Niger Delta by PO Youdeowei, HO Nwankwoala

“…The homogeneous uniformity is an indication of deposition under similar energy conditions. Therefore, adequate attention should be given to the likely physical environmental degradation of river bank failure and liquefaction condition that may evolve as a result of dredging/reclamation work in the area. …”
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The impact of temperature on the shear bond strength of conventional multi-step and self-adhesive orthodontic adhesive systems: an in-vitro study by Grėtė Kazlauskaitė, Rytis Vaitiekūnas, Kristina Lopatienė, Audrius Jutas, Benedikta Palesik, Dalia Smailienė

“…ARI scores were assessed under Carl Zeiss Stemi 2000-CS stereomicroscope with image recording camera AxioCam Mrc5 at ×10 magnification. …”
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HINT1 suppression protects against age-related cardiac dysfunction by enhancing mitochondrial biogenesis by Michio Sato, Tsuyoshi Kadomatsu, Jun Morinaga, Yuya Kinoshita, Daisuke Torigoe, Haruki Horiguchi, Sumio Ohtsuki, Shuji Yamamura, Ryoko Kusaba, Takanori Yamaguchi, Goro Yoshioka, Kimi Araki, Tomohiko Wakayama, Keishi Miyata, Koichi Node, Yuichi Oike

“…Methods: We examined mechanisms underlying age-related cardiac dysfunction using 3- and 24-month-old wild-type mice fed ad libitum or 24-month-old wild-type mice subjected to 70% calorie restriction (CR) starting at 2-month-old. …”
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What made people (more) positive toward the COVID-19 vaccine? Exploring positive and negative deviance perspectives by Mitchell A. M. Matthijssen, Mariëlle Cloin, Florian van Leeuwen, Ien van de Goor, Peter Achterberg

“…The most important barriers and strategies that were identified that could improve vaccination uptake were unrelated to underlying beliefs and worldviews but related to characteristics of the vaccine such as effectiveness and (potential) side-effects. …”
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COVID-19 vaccine uptake in Zimbabwe and Sierra Leone: an application of Health Belief Model constructs by Simon Ssentongo, Alex Muhereza, Morie Mustapha, Ruth Gemi, Dennis Cherian, Rebecca Waugh, Benjamin Crookston, Cougar Hall, Mary Linehan, Hayden Borg, Joshua West

“…This research delves into the underlying factors that influenced these disparities in vaccine acceptance in these two countries, using the Health Belief Model (HBM) and the Theory of Planned Behavior (TPB) as guiding frameworks. …”
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Booster Vaccination against Yellow Fever in Gambian children-(BoVY) -a Phase 3 clinical trial to establish safety and immunogenicity of repeated YF vaccination in healthy Gambian c... by David Jeffries, Caitlin Pley, Beate Kampmann, Mam Nabou Leigh, Julia Strandmark, Ed Clarke, Peter Ndow, Ebrima Kanteh, Amadou Faal, Elishia Roberts

“…Secondary objectives are to characterise the rate of sero-reversion (change from seropositive to seronegative) over a period of 9 months to 8 years following single primary vaccination and to profile the immune response to the booster to explore underlying mechanisms for the longevity of vaccine-induced antibody. …”
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Bioelectric stimulation outperforms brain derived neurotrophic factor in promoting neuronal maturation by María del Pilar Diego-Santiago, María Ujué González, Esther María Zamora Sánchez, Nuria Cortes-Carrillo, Carlos Dotti, Francesc Xavier Guix, Sahba Mobini

“…The neuronal differentiation and maturation of SH-SY5Y cells were tested under several pulsed ES regimes. We identified accumulated charge and effective electric field time as novel criteria for determining optimal ES regimes. …”
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