Functional analysis of heterozygous variants in the SALL1 gene in 2 children with Townes-Brocks syndrome with FSGS by Rong Liang, Bixia Zheng, Chunli Wang, Sanlong Zhao, Wei Zhou, Ying Chen, Ruochen Che

“…Abstract Background To investigate the functional characteristics of heterozygous variants in the SALL1 gene in two children with Townes-Brocks syndrome (TBS), as well as the underlying mechanisms leading to chronic kidney disease. …”
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Effect of remote ischemic preconditioning on perioperative neurocognitive disorder in elderly patients undergoing major surgery and associated genetic variant analysis: a randomize... by Feifei Xu, Tingting Liu, Huiqing Liu, Jiao Deng, Shan He, Zhihong Lu, Haopeng Zhang, Hailong Dong

“…Methods From August 2020, 250 patients scheduled for major surgeries under general anesthesia were screened and 120 patients were randomly assigned to the control group or the RIPC group. …”
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Investigating the Implications of COVID-19 on PM2.5 in Pakistan by Hassaan Sipra, Faheem Aslam, Jabir Hussain Syed, Tahir Mumtaz Awan

“…Furthermore, a varying impact of COVID-19 is found on the strength of multifractality of PM2.5 under consideration. Drastic, significant change is found on the efficiency of air quality in Lahore before and during COVID-19 periods. …”
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Study on the potential diagnostic value of metabolomics changes in different biological fluids for aspiration pneumonia by Lianghui Chen, Yazhen Chen, Fansen Lin, Jianbao Wang, Hongzhi Gao, Yuqi Liu

“…DHEAS was found to be negatively correlated with the Acute Physiology and Chronic Health Evaluation II (APACHE II) (r = − 0.619, p = 0.005) in BALF sample. The area under curve (AUC) values showed that these molecules could serve as effective biomarkers for AP. …”
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Ecological corridor design for ecoclimatic regulation: Species as eco-engineers by Lirong Wu, Matteo Convertino

“…A key question remains about which interconnected areas to protect and restore under the set goals. This study proposes a multi-scale Ecological CORRidor design framework and model (ECORR) for ecoclimatic regulation. …”
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Diagnostic performance of digital breast tomosynthesis (DBT) versus digital mammography (DM) in a population clinically referred for breast imaging – a retrospective cohort study by Naomi Noguchi, Farzaneh Boroumand, Katy Bell, Margaret Pooley, Aileen Zeng, Lauren Arnold, Armando Teixeira-Pinto, Nehmat Houssami

“…Primary outcome was area under receiver operating characteristic curve (AUC-ROC). …”
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Response of Runoff and Sediment Yield from Maize Slope Farmland in Karst Areas to Slope Gradient by WU Guangqin, DAI Quanhou, WANG Yong, DING Pengwei, YAO Yiwen

“…[Methods] Taking the karst maize slope in Guizhou Province as the research object, the artificial simulated rainfall test method was used to investigate the effects of different slopes (5°, 10°, 15°, 20°, 25°) on the runoff and sediment yield patterns of various hydrological pathways under the same rainfall intensity (60 mm/h). [Results] (1) Surface runoff and sediment yield showed a very significant positive correlation with slope gradient at the level of 0.01 (p<0.01). …”
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Design of a Medium Scale Ambient PM2.5 Cleaning System by Sheng-Chieh Chen, Qingfeng Cao, Thomas H. Kuehn, Charles Lo, Manoranjan Sahu, Yelia S. Mayya, David Y. H. Pui

“…The experiments showed that the filter service life is expected to be 2 and 6 months for the prefilter and final filter, respectively, under total suspended particulate and PM2.5 concentrations of 600 and 300 (µg m−3, respectively. …”
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Green remediation of lead (pb) from Pb-toxic soil by combined use of silicon nanomaterials and leguminous Lens culinaris L. plants by Tayyaba Naz, Muhammad Mazhar Iqbal, Bilal Raza, Muhammad Asad Mubeen, Muhammad Ather Nadeem, Abdullah Ahmed Al-Ghamdi, Mohamed S Elshikh, Muhammad Rizwan, Rashid Iqbal

“…Lentil variety Punjab Masoor 2020 was examined under normal and Pb toxic conditions as affected by applied Si and nano-Si. …”
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Plasma Iron Levels at Early Breast Cancer Diagnosis Are Associated With Development of Secondary Metastases: A Single-Center Retrospective Cohort Study by Jasmine De Troy, Sarah-Maria Fendt, Sigrid Hatse, Patrick Neven, Ann Smeets, Annouschka Laenen, Hans Wildiers

“…Further research is needed to understand the underlying mechanisms and to explore the potential of iron-targeted therapies.…”
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Advances in the carbon-ceramic composites oxidation and ablation resistance: A review by Anna Didenko, Alexey Astapov

“…The focus of this study is on the behavior of Cf/UHTC, Cf/C–UHTC, Cf/SiC–UHTC, and Cf/C–SiC–UHTC composites under thermochemical interaction with oxidizing gas flows. …”
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EEG alpha/beta features as a biomarker for quantifying pain in patients with lumbar disk herniation by Rumei Li, Wanqi Shao, Shumei Zhao, Lingli Wang, Chao Yu, Lanying Liu, Kuiying Yin

“…This study aimed to analyze the EEG changes in patients with lumbar disk herniation (LDH) under traditional Chinese medicine small needle knife and to further explore the feasibility of EEG as an indicator of pain assessment in patients with LDH.MethodsThis study conducted resting-state electroencephalography on 20 patients with LDH before and after treatment and on 20 healthy controls, respectively. …”
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Assessment of Reductions in Emission-driven Air Pollution during the Beijing Olympic Games, Shanghai World Expo, Guangzhou Asian Games and Wuhan COVID-19 Lockdown by Ying Li, Haoxiang Xu

“…The emission-driven pollution reduction was largest in the Wuhan COVID-19 lockdown (64% NO2, 54% PM2.5 reductions), followed by Beijing Olympics (42% PM2.5, 31% NO2 reductions), The Wuhan COVID-19 impact on air quality improvement is not as effective as expected especially for O3, which implies the difficulty of air quality attainment under normal, non-lockdown days. Comparison of these events show that shutdown or emission control measures applied to industries and power plants were generally benefit for PM2.5, SO2 and NO2 reduction, while those applied to on-road traffic control are less-effective for reducing NO2 and not works for the mean O3 reduction. …”
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Assessing the Role of Emergency Physicians in Medical Clearance: Predictors of Diagnosing Psychiatric Illness in the Emergency Department – A Retrospective Cross-sectional Study by Ibrahim Khamis Abdullah Almamari, Darpanarayan Hazra, Awatif K. Alsarrai Al-Alawi

“…The majority (335 patients, 92.8%) were diagnosed with primary psychiatric illnesses, while 26 patients (7.2%) had underlying medical conditions contributing to their symptoms. …”
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Cohort profile: Born in Wales—a birth cohort with maternity, parental and child data linkage for life course research in Wales, UK by Amrita Bandyopadhyay, Sarah Davies, Michaela James, Sinead Brophy, Sam Dredge, Hope Jones, Mike J Seaborne, Natasha L Kennedy, Adele Battaglia

“…When considering age distribution, 26.8% of children are under the age of 5, while 63.2% fall within the age range of 5–11.Future plans Born in Wales will expand by 30 000 new births annually in Wales (in NCCHD), while including follow-up data of children and parents already in the database. …”
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Improvement of surgical treatment of an acute biliary pancreatitis at elderly and senile patients by V. I. Midlenko, A. L. Charyshkin, O. V. Midlenko, I. I. Midlenko, V. Yu. Shchegolev

“…The second group (54 patients) was operated through miniaccess with the help of «Generalpurpose frame wound retractor», of them 34 patients with large Hartmann pouch adherent to biliary tracts, were operated by the proposed method (patent of the Russian Federation #2358663 under application #2008103639, priority 30.01.08; registered on 20.06.2009; bulletin #17). …”
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Maternal exposure to deltamethrin during pregnancy and lactation impairs hippocampal learning and memory function of male offspring by ferroptosis by Shasha Huang, Wanqi Li, Dengke Wang, Huiwen Feng, Bo Wang, Xinyu Dong, Wei Zhao, Dan Liu, Yuan Wang

“…In vitro,we selected HT-22 cells to be exposed to DM under the intervention of ferrostatin-1 and pifithrin-α. …”
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Diabetes and tuberculosis: a systematic review and meta-analyis of mendelian randomization evidence by Ivaan Pitua, Raafidha Raizudheen, Mark Muyanja, Joseph Nyero, Morrish Okello Obol

“…Future MR studies should include diverse populations to enhance generalizability and explore genetic mechanisms underlying this association.…”
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Using new control strategies to improve the effectiveness and efficiency of the hybrid power system based on the battery storage system by Karima Boutaghane, Habib Benbouhenni, Nedjoua Bennecib, Ilhami Colak, Z. M. S. Elbarbary, Saad F. Al-Gahtani

“…The HES was realized using MATLAB, where the competence is tested under different work scenarios. The results showed excellent efficacy of the designed control and were compared with conventional control. …”
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Shramahara Mahakasya, a traditional polyherbal formulation, induces anti-anxiety activity in hippocampal neurons by effectuating SOD2-mediated protection against oxidative stress by Saakshi Saini, Viney Kumar, Swati Haldar, Samrat Chauhan, Pratibha Demiwal, Souvik Ghosh, Sumeet Gupta, Debabrata Sircar, Bidhan Mahajon, Partha Roy

“…The anxiolytic activity of SM (50 and 100 mg/kg) was assessed in a caffeine (50 mg/kg) induced anxiety model of Sprague Dawley rats. The possible underlying mechanisms for the neuroprotective and anxiolytic activities of SM were explored through biochemical assays and brain histology. …”
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