Microglia TRPC1 SUMOylation drives neuroinflammation after stroke by modulating NLRP3 activity via increasing TRPC1 interaction with ARRB2 by Huinan Zhang, Xinzhe Du, Tian Gao, Xing Wang, Huifeng Zhang, Manyang Yu, Jing Huang

“…Microglial canonical transient receptor potential channel 1 (TRPC1) has been proposed to influence neuroinflammation after cerebral ischemia and reperfusion injury (CIRI), however, the underlying mechanism remains poorly understood. This study demonstrates that TRPC1 is modified by small ubiquitin-related modifier (SUMO)ylation. …”
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Characteristics of PM and PAHs Emitted from Oil-fired Process by Ming Wei Chang, Minh Man Trinh, Chian Kou Lien, Moo Been Chang

“…The results show that the NO concentration (90 ppm) emitted from the oil-fired boiler at low loading was lower than that of the high loading (176 ppm) while SO2 concentrations are close under two loading conditions. In terms of particulate matter, the concentrations of FPM, FPM2.5, and CPM measured in the stack at low loading were 0.2, 0.1, and 51.2 mg Nm−3, respectively. …”
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Jilin Province of China, 1949–1979: History of Regional and Demographic Development by Svetlana B. Makeeva

“…The paper shall consider some peculiar features of economic processes in the evolution of Jilin Province from 1949 to 1979; identify key trends in ethnic, urban/spatial, and migration processes; determine the causes and consequences of high fertility, low mortality, and a younger age population structure in Jilin Province during the period under review. Materials and methods. The article employs quite a variety of sources on China’s historical demography: population censuses, statistical collections, materials of five-year plans. …”
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Predictors of 7-day symptomatic hemorrhagic transformation in patients with acute ischemic stroke and proposal of a novel screening tool: A retrospective cohort study by Mehmet Muzaffer Islam, Cemrenur Uygun, Melike Delipoyraz, Merve Osoydan Satici, Servan Kurt, Enis Ademoglu, Serkan Emre Eroglu

“…Mechanical thrombectomy, atrial fibrillation, and diabetes mellitus were the independent predictors (P < 0.001, P = 0.003, P = 0.006, respectively). The mean area under the curve of the receiver operating characteristics of the model was 0.916 (95% confidence interval [CI] = 0.876–0.957). …”
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Cardiovascular disease risk prediction by Framingham risk score in women with polycystic ovary syndrome by Mina Amiri, Maryam Mousavi, Mahsa Noroozzadeh, Fereidoun Azizi, Fahimeh Ramezani Tehrani

“…Model accuracy was evaluated using the C-statistic, while discrimination and calibration were assessed via the ROC curve, area under the ROC curve (AUC) statistics, and the Hosmer- Lemeshow test. …”
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Proteomics unveil candidate biomarkers and pathogenesis of subacute thyroiditis by Litong Ran, Xiufei Liu, Yongfeng Tian, Jiaran Zhu, Zhengyuan Gong, Qiao Qiao, Xin Jiang, Yuren Wang, Guojun Yang, Hongting Zheng, Yi Zheng, Hua Qu

“…The results revealed that each factor demonstrated an area under the curve score above 0.8. Thus, these high-abundance proteins can potentially serve as biomarkers for SAT diagnosis and outcome prediction. …”
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Are there benefits of culture-based detection of Mycobacterium avium spp paratuberculosis over histopathology? by Motlatso T. Hlokwe, Nomawethu S. Masina, Boitumelo Letsoko, Sewellyn C. Davey, Anita L. Michel

“…The current work assessed the diagnostic value of the VersaTREK automated liquid culture system in isolating Mycobacterium avium subspecies paratuberculosis (MAP) from faecal and intestinal tissue samples from ovine under South African conditions and compared it with the current method of choice, histopathological examination. …”
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Outcome of Excision with Primary Midline Closure for Sacrococcygeal Pilonidal Sinus Disease by Bahzad Waso Hamad

“…This is a retrospective study with telephone contact and review of 36 patients operated for Sacrococcygeal pilonidal sinus disease from January 2011 through January 2016 under care of one consultant surgeon (the Author) in Public and Private Hospitals in Rania, Sulaimani, Iraq. …”
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DEEP STRUCTURE, TECTONIC EVOLUTION AND HYDROCARBON POTENTIAL OF THE KALAMIT SWELL (NORTHWESTERN SHELF OF THE BLACK SEA) ACCORDING TO DENSITY MODELING DATA by M.V. Kozlenko, Yu.V. Kozlenko

“…The sublatitudinal North Crimean region of the Baikalides and the greenschist belt of the Moesian Plate in the NW-SW direction developed under the influence of separate tectonic impulses, as they were delimited by a sharply unconformable meridional syncline zone in the middle part of the swell. …”
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Immediate and Intermediate-Term Outcomes of Infants With Transposition of Great Arteries Who Underwent Balloon Atrial Septostomy in Sudan by Sulafa K. M. Ali, Amna Elsheikh, Mohammed Abdulrahman Alhassan

“…Pre-BAS median oxygen saturation was 48 (Interquartile Range (IQR) 40–60%). BAS was performed under fluoroscopy and echocardiography guidance with immediate success achieved in 98% of patients. …”
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Impoundments facilitate upstream invasion and introgression: Case studies of fluvial black basses (Micropterus spp.) in the southeastern USA. by Andrew T Taylor, Michael D Tringali, James M Long

“…Introgression rates also varied markedly across the species pairs studied-from very little introgression to the onset of hybrid swarming-illustrating the importance of underlying eco-evolutionary mechanisms such as habitat alteration, propagule pressure, and reproductive isolation. …”
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A parametric study of polymer-enhanced CO2 injection in a light-oil reservoir using full-physics simulation by Rapheephan Laochamroonvorapongse, Falan Srisuriyachai, Jirawat Chewaroungroaj

“…Abstract This study aims to assess the performance of polymer-enhanced CO2 injection in a light-oil reservoir under various reservoir geometries, parameters, and polymer properties. …”
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Classification of risk for transmission of vaccine-preventable diseases in Brazilian municipalities: comparative analysis before and after the national movement for vaccination and... by Ana Catarina de Melo Araújo, Thales Philipe Rodrigues da Silva, Janaina Fonseca Almeida Souza, Krishna Mara Rodrigues Freire, Fernanda Penido Matozinhos, Eder Gatti Fernandes

“…Methods This is an epidemiological, ecological study using secondary data on vaccination coverage, dropout rates, and homogeneity of vaccination coverage (HCV) for ten immunobiologicals recommended for children under 2 years of age. The study aims to compare the years 2022 and 2023 in Brazil. …”
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The Predictive Value of the Pentraxin 3 Concentration in Cumulus Cell Culture Media for the Embryo Implantation by Tulay Irez, Yavuz Sahin, Eduard Malik, Onur Guralp

“…There was no pregnancy under the cut-off value of 60 ng/mL, whereby seven women had good quality grade 1 oocytes according to the traditional morphological criteria. …”
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Image-based anomaly detection in low-light industrial environments with feature enhancement by Dinh-Cuong Hoang, Phan Xuan Tan, Anh-Nhat Nguyen, Son-Anh Bui, Ta Huu Anh Duong, Tuan-Minh Huynh, Duc-Manh Nguyen, Viet-Anh Trinh, Quang-Huy Ha, Nguyen Dinh Bao Long, Duc-Thanh Tran, Xuan-Tung Dinh, Van-Hiep Duong, Tran Thi Thuy Trang

“…In this paper, we present DarkAD, a novel end-to-end approach specifically designed to address the difficulties of anomaly detection under low-light conditions. Our framework features a Dark-Aware Feature Adapter (DAFA), which enhances feature extraction by integrating two key modules: Frequency-based Feature Enhancement (FFE) and Illumination-aware Feature Enhancement (IFE). …”
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Associations and potential epigenetic changes between air pollution and osteoarthritis risk and survival: Insights from a prospective cohort study by Jing Qian, Jiahao Zhu, Yifan Wang, Ruoqi Dai, Jingyou Miao, Ye Yang, Wenxia Zhao, Jing Wang, Lilu Ding, Dan Zhou, Min Yu, Yingjun Li

“…Conclusion: Long-term exposure to air pollution was associated with an increased risk of OA in the population and poorer survival outcomes for OA patients, with epigenetic changes in GDF5 potentially playing a role in the underlying mechanisms.…”
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Designing multi-function rapid right angle set slurry compositions for a high pressure-high temperature well by Pooria Kianoush, Mostafa Gomar, Nasser Keshavarz Faraj Khah, Seyednooroldin Hosseini, Ali Kadkhodaie, Shahaab Varkouhi

“…The designed slurry achieved an API fluid loss of 4.5 cc and 15 cc, transition times (30BC to 70BC) under 1 minute, with compressive strengths of 25.29 MPa and 35.44 MPa, respectively, compared to ordinary slurries that typically exhibited fluid losses greater than 50 cc and lower strengths. …”
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Oversized cells activate global proteasome-mediated protein degradation to maintain cell size homeostasis by Shixuan Liu, Ceryl Tan, Chloe Melo-Gavin, Miriam B Ginzberg, Ron Blutrich, Nish Patel, Michael Rape, Kevin G Mark, Ran Kafri

“…Here, we quantified global rates of protein synthesis and degradation in cells of varying sizes, both under unperturbed conditions and in response to perturbations that trigger size-dependent compensatory growth slowdown. …”
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Combined morphology and radiomics of intravoxel incoherent movement as a predictive model for the pathologic complete response before neoadjuvant chemotherapy in patients with brea... by Yunyan Zheng, Hui Zhang, Huijian Chen, Yang Song, Ping Lu, Mingping Ma, Mengbo Lin, Muzhen He

“…The performance evaluation of the nomogram involved the area under the receiver operating characteristic curve (AUC), a decision curve analysis, and the calibration slope.ResultsIn an assessment for predicting pCR, the radiomics model displayed an AUC of 0.778 and 0.703 for the training and testing cohorts, respectively. …”
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A missense variant in the SOX5 gene (c.221C > T) is associated with intellectual disability by Xiujuan Yang, Zhongzhi Gan, Xiaoling Guo, Xiang Huang, Juan Liu, Yingchun Zheng, Xiaoqiang Zhou, Jingli Lian, Yue Liu, Tingting Yang, Chao Li, Fenying Chen, Fei He, Xiangmin Xu, Yasi Zhou, Qian Liu, Xingkun Yang, Fu Xiong

“…Results A previously identified missense variant (c.221C > T) in the SOX5 gene was determined to be the underlying cause of intellectual disability in a Chinese family. …”
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