Assessing Walkability in Sulaimani City Center by Roza Abdullatif Radha, Rozhen Kamal Mohammed-Amin, Alan Faraydoon Ali

“…Since walkability character can be contextual and affected by different socio-economic and environmental factors and dynamics, systematic and comprehensive assessment of under-researched environments and city centers are essential. …”
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Leveraging the Aspects of Knowledge, Attitude, and Practice as an Alternative to Prevent Detrimental Impacts of Stunting by Novia Luthviatin, Ninna Rohmawati, Dwi Martiana Wati, Jihan Darmaningtyas, Yessinia Hanatha Pasha

“…Background: The prevalence of stunting in Indonesia is recorded at 21.6% among children under five, while the WHO target for 2025 is less than 14%. …”
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Finger roots (Uvaria chemea) and African greenheart (Cylicodiscus gabunensis): Alternative potent therapy to sildenafil in erectile dysfunction by Etukudo Okon Jimmy, Grace Edet Bassey, Abijah Ekwere, Udoh Idorenyin Umoh, Adeyemi Fatai Odetayo, Udoh Nsikan Malachy

“…Further investigations are necessary to elucidate the underlying mechanisms of action, determine optimal dosages, and evaluate the long-term safety profiles of these herbal extracts for potential human applications.…”
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Dose-dependent effects of hydroquinone on liver injury and lipid dysregulation based on SCD1/AMPK signaling pathway in C57BL/6 mice by Lijun Zou, Fen Lin, Jinying Wen, Jinyu Huang, Yue Tan, Hui Huang, Gonghua Hu

“…We administered HQ at doses of 0, 12.5, 25.0, and 50.0 mg/kg over a period of 13 weeks, followed by biochemical analyses, RNA sequencing, and Western blotting to elucidate the underlying mechanisms. Our findings indicated that lower doses of HQ (12.5 and 25.0 mg/kg) led to lipid accumulation in the liver, accompanied by increased liver TG and serum TC. …”
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Association between living arrangements, social support, and depression among middle-aged and older adults: a mediation analysis from the CHARLS survey by Fenghua Jin, Yixuan Hu

“…Causal mediation analysis under a counterfactual framework was employed to evaluate the mediation effect of social support in the association between living arrangements and depression, which was performed by fitting two logistic regression models. …”
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Human microbiome, applied to clinical practice by V. T. Ivashkin, K. V. Ivashkin

“…The model of bacterial involvement in colorectal cancer progression is under study. Besides, the increasing attention of doctors and scientists is attracted to the issue intestinal microflora changes at antibiotic treatment. …”
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Fingertip traumatic amputations in children. Treatment with semiocclusive foil dressings-preliminary results by Dimitar Trizlov, Dimitar Raykov, Stoyan Ivanov, Ivan Trizlov

“… Introduction: Traumatic fingertip amputations in childhood constitute 2% of all hand injuries in individuals under the age of 14. These injuries have a significant impact on the psychological and emotional well-being of both the children and their parents. …”
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GEOPOLITICAL VARIATION IN THE REPORTAGE OF SECURITY BY THE NATION AND DAILY TRUST NEWSPAPERS (2010-2020): A PROGNOSIS by M. M. NURUDDEN, M. M. NURUDDEN

“… This study explores the geopolitical trajectory in the reportage of security issues in Nigeria by The Nation and Daily Trust newspapers between 2010 and 2020.The two national dailies have within the period under study engaged reckless reportage of insecurity news in the geopolitics of information dissemination, which endangers the lives of many innocent Nigerians in order to favour their states of operation and deepen acceptability in their constituencies, hence promoting unhealthy Northern and Southern dichotomy to the detriment of national security. …”
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Gingival fibroblast suppress the osteogenesis process mediated by bone substitute materials via WNT/β-catenin signaling pathway in vitro and in vivo by Guanqi Liu, Jiahui Lin, Xiaoyan Chen, Runheng Liu

“…This study aimed to investigate the impact of gingival fibroblasts on the osteogenic differentiation of MSCs in the presence of BSMs and to elucidate the underlying mechanisms, focusing on the WNT/β-catenin signaling pathway.MethodsGingival fibroblasts and BSMs co-culture conditioned medium was used to culture MMSCs, and the expression and activity of alkaline phosphatase (ALP), as well as osteogenic and fibrogenic gene and protein expression, were evaluated. …”
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Myocardial functional recovery following durable ventricular assist device in children by Bhavikkumar Langanecha, Osami Honjo, Alyssa Power, Oshri Zaulan, Christoph Haller, Kristen George, Linda Fazari, Andrea Maurich, David Chiasson, Aamir Jeewa

“…Of those, 7 of 9 (77%) were under 2 years of age and 6 of 9 (67%) were supported for >90 days. …”
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Association of systemic vitamin D on the course of dengue virus infection in adults: a single-centre dengue cohort study at a large institution in Singapore by Sapna P Sadarangani, Htet Lin Htun, Weiping Ling, Robert Hawkins, Tsin Wen Yeo, Laura Rivino, Paul A MacAry, Yee-Sin Leo

“…Further studies investigating the underlying immune mechanisms and effects on the vascular endothelium are needed.…”
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Enhanced CO2 Capture Performance Using Methyl Diethanolamine-functionalized Silica Gels: Assessing CO2 Capture Capacity by Petpitcha Boonmatoon, Pacharapol Nokpho, Pornpote Piumsomboon, Benjapon Chalermsinsuwan

“…They provide several benefits, such as high adsorption capacity under dry conditions at ambient temperature, along with low energy requirements for regeneration. …”
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Squamous Cell Carcinoma of Nasofacial Groove by Tamajit Sau, Saumitra Kumar, Ankita Atin Mukherjee, Debalina Mazumdar

“…Surgical excision was done under general anaesthesia. Gross examination  showed predominantly solid and grey mass. …”
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SARS-CoV-2 ORF3a accessory protein is a water-permeable channel that induces lysosome swelling by Antonio Michelucci, Luigi Sforna, Riccardo Focaia, Maria Vittoria Leonardi, Angela Di Battista, Giorgia Rastelli, Simone Vespa, Simona Boncompagni, Manlio Di Cristina, Luigi Catacuzzeno

“…However, the mechanism underlying this process remains unclear. While seminal studies suggested ORF3a being a cation-selective channel (i.e., viroporin), recent works disproved this conclusion. …”
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Humanising nanotoxicology: replacement of animal-derived products in the application of integrated approaches to testing and assessment of nanomaterial inhalation hazard by Roma Fraser, Keira Campbell, Pawel Pokorski, Eve MacKinnon, Katie McAllister, Karla B. Neves, Fiona Murphy

“…Significant differences in acellular NM reactivity and dramatic changes in A549 cell growth rates and responses to NMs were observed under different media conditions. Our findings demonstrate that variations in experimental setup can fundamentally impact NM hazard assessment, influencing the interpretation of results within specific assays and across tiered testing strategies. …”
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Disorders of Adipose Tissue and Lipodystrophies: Causes, Consequences, and Treatment Perspectives by Rosińska Kamila Rosińska, Ewelina Justyna Janicka, Julia Natalia Skibicka, Monika Niedźwiedzka, Mateusz Rosiński

“…OBJECTIVE: This study aims to analyze the pathophysiology, diagnosis, and treatment of lipodystrophies, particularly focusing on congenital, acquired, and HIV-associated forms. It explores the underlying metabolic mechanisms, diagnostic challenges, and current and future therapeutic approaches, including metreleptin and other strategies. …”
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Feasibility and safety of zero-fluoro, “apron-less” approach to repeat pulmonary vein isolation procedures using radiofrequency energy after initial cryoballoon ablation by Vedran Velagic, Vedran Pasara, Ivan Prepolec, Andrija Nekic, Zvonimir Katic, Davor Milicic

“…Repeat procedures were performed under conscious sedation and with intracardiac echo (ICE) and 3D mapping system - without the use of fluoroscopy and lead aprons. …”
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Estimating wolf abundance with unverified methods by Adrian Treves, Francisco J. Santiago-Ávila

“…Verification will require independent replication and unbiased tests at multiple scales in multiple habitats under different human-induced mortality rates and rigorous independent review before the new methods are considered reliable.…”
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The OXT rs6133010 variant modulates susceptibility to psychiatric symptoms during withdrawal in patients with alcohol dependence by Guanghui Shen, Wei Wang, Yuyu Wu, Xinguang Luo, Kexin Wang, Yu-Hsin Chen, Yimin Kang, Yanlong Liu, Fan Wang, Li Chen

“…Path analysis unveiled the underlying mechanism of OXT symptom regulation. Conclusion This study presents novel evidence that OXT rs6133010 specifically modulates psychiatric symptoms in AD. …”
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Blood-based biomarkers suggest prolonged axonal Injury following pediatric mild traumatic brain injury by Andrew R. Mayer, Tracey V. Wick, Jessica R. McQuaid, Masen L. Boucher, Andrew B. Dodd, Cidney R. Robertson-Benta, Harm J. van der Horn, Erik B. Erhardt, Robert E. Sapien, Rawan Tarawneh, Rebekah Mannix

“…Abstract Pediatric mild traumatic brain injury (pmTBI) affects millions of youth annually but underlying pathophysiology and time for physiological recovery remains unknown. …”
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